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Vulvar basaloid squamous cell carcinoma

MedGen UID:
384496
Concept ID:
C2211850
Neoplastic Process
Synonyms: Vulvar Basaloid Carcinoma; vulvar basaloid carcinoma; Vulvar Basaloid Squamous Cell Carcinoma; vulvar basaloid squamous cell carcinoma
 
Monarch Initiative: MONDO:0004090

Definition

A squamous cell carcinoma that arises from the vulva and is characterized by the presence of nests of malignant basaloid cells with a scant amount of cytoplasm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulvar basaloid squamous cell carcinoma

Professional guidelines

PubMed

Heller DS, Day T, Allbritton JI, Scurry J, Radici G, Welch K, Preti M; ISSVD Difficult Pathologic Diagnoses Committee
J Low Genit Tract Dis 2021 Jan 1;25(1):57-70. doi: 10.1097/LGT.0000000000000572. PMID: 33105449Free PMC Article
de Sanjosé S, Alemany L, Ordi J, Tous S, Alejo M, Bigby SM, Joura EA, Maldonado P, Laco J, Bravo IG, Vidal A, Guimerà N, Cross P, Wain GV, Petry KU, Mariani L, Bergeron C, Mandys V, Sica AR, Félix A, Usubutun A, Seoud M, Hernández-Suárez G, Nowakowski AM, Wilson G, Dalstein V, Hampl M, Kasamatsu ES, Lombardi LE, Tinoco L, Alvarado-Cabrero I, Perrotta M, Bhatla N, Agorastos T, Lynch CF, Goodman MT, Shin HR, Viarheichyk H, Jach R, Cruz MO, Velasco J, Molina C, Bornstein J, Ferrera A, Domingo EJ, Chou CY, Banjo AF, Castellsagué X, Pawlita M, Lloveras B, Quint WG, Muñoz N, Bosch FX; HPV VVAP study group
Eur J Cancer 2013 Nov;49(16):3450-61. Epub 2013 Jul 22 doi: 10.1016/j.ejca.2013.06.033. PMID: 23886586

Recent clinical studies

Etiology

Milliken S, May J, Sanderson PA, Congiu MA, D'Oria O, Golia D'Augè T, Caruso G, DI Donato V, Benedetti Panici P, Giannini A
Minerva Obstet Gynecol 2021 Apr;73(2):160-165. Epub 2020 Dec 11 doi: 10.23736/S2724-606X.20.04743-7. PMID: 33306289
Heller DS, Day T, Allbritton JI, Scurry J, Radici G, Welch K, Preti M; ISSVD Difficult Pathologic Diagnoses Committee
J Low Genit Tract Dis 2021 Jan 1;25(1):57-70. doi: 10.1097/LGT.0000000000000572. PMID: 33105449Free PMC Article
Jenkins TM, Mills AM
Semin Diagn Pathol 2021 Jan;38(1):27-36. Epub 2020 Sep 6 doi: 10.1053/j.semdp.2020.09.006. PMID: 32948383
Watkins JC
Surg Pathol Clin 2019 Jun;12(2):249-261. Epub 2019 Apr 5 doi: 10.1016/j.path.2019.01.001. PMID: 31097103
Velazquez EF, Chaux A, Cubilla AL
Semin Diagn Pathol 2012 May;29(2):96-102. doi: 10.1053/j.semdp.2011.08.009. PMID: 22641959

Diagnosis

Heller DS, Day T, Allbritton JI, Scurry J, Radici G, Welch K, Preti M; ISSVD Difficult Pathologic Diagnoses Committee
J Low Genit Tract Dis 2021 Jan 1;25(1):57-70. doi: 10.1097/LGT.0000000000000572. PMID: 33105449Free PMC Article
Jenkins TM, Mills AM
Semin Diagn Pathol 2021 Jan;38(1):27-36. Epub 2020 Sep 6 doi: 10.1053/j.semdp.2020.09.006. PMID: 32948383
Day T, Marzol A, Pagano R, Jaaback K, Scurry J
J Low Genit Tract Dis 2020 Oct;24(4):392-398. doi: 10.1097/LGT.0000000000000569. PMID: 32976294Free PMC Article
Watkins JC
Surg Pathol Clin 2019 Jun;12(2):249-261. Epub 2019 Apr 5 doi: 10.1016/j.path.2019.01.001. PMID: 31097103
Rakislova N, Saco A, Sierra A, Del Pino M, Ordi J
Adv Anat Pathol 2017 Jul;24(4):201-214. doi: 10.1097/PAP.0000000000000155. PMID: 28590952

Therapy

Day T, Otton G, Jaaback K, Weigner J, Scurry J
J Low Genit Tract Dis 2018 Apr;22(2):159-165. doi: 10.1097/LGT.0000000000000384. PMID: 29470358Free PMC Article
Toby M, Conway K, Sethi G, Lewis F
Int J STD AIDS 2016 Dec;27(14):1253-1256. Epub 2015 Oct 14 doi: 10.1177/0956462415611513. PMID: 26472432
Shiozaki T, Tabata T, Toriyabe K, Motohashi T, Kondo E, Tanida K, Okugawa T, Sagawa N
Int J Clin Oncol 2011 Oct;16(5):610-2. Epub 2011 Jan 21 doi: 10.1007/s10147-010-0180-4. PMID: 21249413
Sun Y, Hildesheim A, Brinton LA, Nasca PC, Trimble CL, Kurman RJ, Viscidi RP, Shah KV
Gynecol Oncol 1996 Nov;63(2):200-3. doi: 10.1006/gyno.1996.0306. PMID: 8910627

Prognosis

Milliken S, May J, Sanderson PA, Congiu MA, D'Oria O, Golia D'Augè T, Caruso G, DI Donato V, Benedetti Panici P, Giannini A
Minerva Obstet Gynecol 2021 Apr;73(2):160-165. Epub 2020 Dec 11 doi: 10.23736/S2724-606X.20.04743-7. PMID: 33306289
Jenkins TM, Mills AM
Semin Diagn Pathol 2021 Jan;38(1):27-36. Epub 2020 Sep 6 doi: 10.1053/j.semdp.2020.09.006. PMID: 32948383
Watkins JC
Surg Pathol Clin 2019 Jun;12(2):249-261. Epub 2019 Apr 5 doi: 10.1016/j.path.2019.01.001. PMID: 31097103
Rakislova N, Saco A, Sierra A, Del Pino M, Ordi J
Adv Anat Pathol 2017 Jul;24(4):201-214. doi: 10.1097/PAP.0000000000000155. PMID: 28590952
Del Pino M, Rodriguez-Carunchio L, Ordi J
Histopathology 2013 Jan;62(1):161-75. Epub 2012 Nov 27 doi: 10.1111/his.12034. PMID: 23190170

Clinical prediction guides

Stolnicu S, Allison D, Praiss AM, Tessier-Cloutier B, Momeni Boroujeni A, Flynn J, Iasonos A, Serrette R, Hoang L, Patrichi A, Terinte C, Pesci A, Mateoiu C, Lastra RR, Kiyokawa T, Ali-Fehmi R, Kheil M, Oliva E, Devins KM, Abu-Rustum NR, Soslow RA
Am J Surg Pathol 2023 Dec 1;47(12):1376-1389. Epub 2023 Sep 13 doi: 10.1097/PAS.0000000000002122. PMID: 37702216Free PMC Article
Milliken S, May J, Sanderson PA, Congiu MA, D'Oria O, Golia D'Augè T, Caruso G, DI Donato V, Benedetti Panici P, Giannini A
Minerva Obstet Gynecol 2021 Apr;73(2):160-165. Epub 2020 Dec 11 doi: 10.23736/S2724-606X.20.04743-7. PMID: 33306289
Day T, Marzol A, Pagano R, Jaaback K, Scurry J
J Low Genit Tract Dis 2020 Oct;24(4):392-398. doi: 10.1097/LGT.0000000000000569. PMID: 32976294Free PMC Article
Santos M, Landolfi S, Olivella A, Lloveras B, Klaustermeier J, Suárez H, Alòs L, Puig-Tintoré LM, Campo E, Ordi J
Am J Surg Pathol 2006 Nov;30(11):1347-56. doi: 10.1097/01.pas.0000213251.82940.bf. PMID: 17063073
Frisch M, Fenger C, van den Brule AJ, Sørensen P, Meijer CJ, Walboomers JM, Adami HO, Melbye M, Glimelius B
Cancer Res 1999 Feb 1;59(3):753-7. PMID: 9973228

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