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Papulopustular Rash

MedGen UID:
388569
Concept ID:
C2609319
Sign or Symptom

Definition

Skin eruption consisting of papules and pustules, most often appearing in the face, scalp, and upper trunk. It is usually caused by corticosteroids or epidermal growth factor receptor inhibitors. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPapulopustular Rash

Professional guidelines

PubMed

Nowaczyk J, Fret K, Kaminska-Winciorek G, Rudnicka L, Czuwara J
Anticancer Drugs 2023 Sep 1;34(8):942-948. Epub 2023 Jan 24 doi: 10.1097/CAD.0000000000001494. PMID: 36708507Free PMC Article
Tohyama M, Hamada M, Harada D, Kozuki T, Nogami N, Monden N, Kajiwara T, Nishina T
J Dermatol 2020 Feb;47(2):121-127. Epub 2019 Dec 5 doi: 10.1111/1346-8138.15170. PMID: 31803963
Hofheinz RD, Segaert S, Safont MJ, Demonty G, Prenen H
Crit Rev Oncol Hematol 2017 Jun;114:102-113. Epub 2017 Apr 11 doi: 10.1016/j.critrevonc.2017.03.032. PMID: 28477738

Recent clinical studies

Etiology

Saadet ED, Tek I
Int J Dermatol 2022 Dec;61(12):1519-1526. Epub 2022 Jul 22 doi: 10.1111/ijd.16361. PMID: 35867950
Yalici-Armagan B, Ayanoglu BT, Demirdag HG
Cutan Ocul Toxicol 2019 Sep;38(3):261-266. Epub 2019 May 7 doi: 10.1080/15569527.2019.1594874. PMID: 31010330
Hofheinz RD, Segaert S, Safont MJ, Demonty G, Prenen H
Crit Rev Oncol Hematol 2017 Jun;114:102-113. Epub 2017 Apr 11 doi: 10.1016/j.critrevonc.2017.03.032. PMID: 28477738
Cignola S, Gonella S, Alessandra B, Palese A
Eur J Oncol Nurs 2016 Feb;20:133-9. Epub 2015 Jul 15 doi: 10.1016/j.ejon.2015.07.003. PMID: 26187661
Bergman H, Walton T, Del Bel R, Seki JT, Rafii A, Xu W, Koren G, Shear N, Krzyzanowska MK, Howell D, Liu G
J Am Acad Dermatol 2014 Oct;71(4):754-9. Epub 2014 Jul 29 doi: 10.1016/j.jaad.2014.06.011. PMID: 25085331

Diagnosis

Finazzi A, Cosentini R
N Engl J Med 2023 Mar 9;388(10):e30. Epub 2023 Mar 4 doi: 10.1056/NEJMicm2209759. PMID: 36876757
Nowaczyk J, Fret K, Kaminska-Winciorek G, Rudnicka L, Czuwara J
Anticancer Drugs 2023 Sep 1;34(8):942-948. Epub 2023 Jan 24 doi: 10.1097/CAD.0000000000001494. PMID: 36708507Free PMC Article
Tohyama M, Hamada M, Harada D, Kozuki T, Nogami N, Monden N, Kajiwara T, Nishina T
J Dermatol 2020 Feb;47(2):121-127. Epub 2019 Dec 5 doi: 10.1111/1346-8138.15170. PMID: 31803963
Yalici-Armagan B, Ayanoglu BT, Demirdag HG
Cutan Ocul Toxicol 2019 Sep;38(3):261-266. Epub 2019 May 7 doi: 10.1080/15569527.2019.1594874. PMID: 31010330
Lacouture ME, Boerner SA, Lorusso PM
Clin Lung Cancer 2006 Dec;8 Suppl 1:S36-42. doi: 10.3816/clc.2006.s.012. PMID: 17239289

Therapy

Tohyama M, Hamada M, Harada D, Kozuki T, Nogami N, Monden N, Kajiwara T, Nishina T
J Dermatol 2020 Feb;47(2):121-127. Epub 2019 Dec 5 doi: 10.1111/1346-8138.15170. PMID: 31803963
Annunziata MC, De Stefano A, Fabbrocini G, Leo S, Marchetti P, Romano MC, Romano I
Clin Drug Investig 2019 Sep;39(9):825-834. doi: 10.1007/s40261-019-00811-7. PMID: 31264159
Yalici-Armagan B, Ayanoglu BT, Demirdag HG
Cutan Ocul Toxicol 2019 Sep;38(3):261-266. Epub 2019 May 7 doi: 10.1080/15569527.2019.1594874. PMID: 31010330
Eaby-Sandy B, Lynch K
Semin Oncol Nurs 2014 Aug;30(3):147-54. doi: 10.1016/j.soncn.2014.06.001. PMID: 25085026
Lacouture ME, Boerner SA, Lorusso PM
Clin Lung Cancer 2006 Dec;8 Suppl 1:S36-42. doi: 10.3816/clc.2006.s.012. PMID: 17239289

Prognosis

Nowaczyk J, Fret K, Kaminska-Winciorek G, Rudnicka L, Czuwara J
Anticancer Drugs 2023 Sep 1;34(8):942-948. Epub 2023 Jan 24 doi: 10.1097/CAD.0000000000001494. PMID: 36708507Free PMC Article
Tohyama M, Hamada M, Harada D, Kozuki T, Nogami N, Monden N, Kajiwara T, Nishina T
J Dermatol 2020 Feb;47(2):121-127. Epub 2019 Dec 5 doi: 10.1111/1346-8138.15170. PMID: 31803963
Bergman H, Walton T, Del Bel R, Seki JT, Rafii A, Xu W, Koren G, Shear N, Krzyzanowska MK, Howell D, Liu G
J Am Acad Dermatol 2014 Oct;71(4):754-9. Epub 2014 Jul 29 doi: 10.1016/j.jaad.2014.06.011. PMID: 25085331
Li T, Perez-Soler R
Target Oncol 2009 Apr;4(2):107-19. Epub 2009 May 19 doi: 10.1007/s11523-009-0114-0. PMID: 19452131
Peréz-Soler R, Saltz L
J Clin Oncol 2005 Aug 1;23(22):5235-46. doi: 10.1200/JCO.2005.00.6916. PMID: 16051966

Clinical prediction guides

Tohyama M, Hamada M, Harada D, Kozuki T, Nogami N, Monden N, Kajiwara T, Nishina T
J Dermatol 2020 Feb;47(2):121-127. Epub 2019 Dec 5 doi: 10.1111/1346-8138.15170. PMID: 31803963
Sanmartín O
Curr Probl Dermatol 2018;53:93-104. Epub 2017 Nov 7 doi: 10.1159/000479198. PMID: 29131041
Cignola S, Gonella S, Alessandra B, Palese A
Eur J Oncol Nurs 2016 Feb;20:133-9. Epub 2015 Jul 15 doi: 10.1016/j.ejon.2015.07.003. PMID: 26187661
Lacouture ME, Boerner SA, Lorusso PM
Clin Lung Cancer 2006 Dec;8 Suppl 1:S36-42. doi: 10.3816/clc.2006.s.012. PMID: 17239289
Peréz-Soler R, Saltz L
J Clin Oncol 2005 Aug 1;23(22):5235-46. doi: 10.1200/JCO.2005.00.6916. PMID: 16051966

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