U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Osteoarthritis, spine

MedGen UID:
389941
•Concept ID:
C2350242
•
Disease or Syndrome
Synonyms: Osteoarthritis of Spine; Osteoarthritis of the Spine; Osteoarthritis, Spinal; Osteoarthritis, Spine; Spinal Osteoarthritis; Spine Osteoarthritis
SNOMED CT: Spinal osteoarthritis (68859000); Osteoarthritis of spine (8847002); OA - Osteoarthritis of the spine (8847002); OA - Osteoarthritis of spine (8847002)
 
Monarch Initiative: MONDO:0006630

Definition

A degenerative joint disease involving the spine. It is characterized by progressive deterioration of the spinal articular cartilage (cartilage, articular), usually with hardening of the subchondral bone and outgrowth of bone spurs (osteophyte). [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOsteoarthritis, spine

Professional guidelines

PubMed

Comparison of lifetime incremental cost:utility ratios of surgery relative to failed medical management for the treatment of hip, knee and spine osteoarthritis modelled using 2-year postsurgical values.
Tso P, Walker K, Mahomed N, Coyte PC, Rampersaud YR
Can J Surg 2012 Jun;55(3):181-90. doi: 10.1503/cjs.033910. PMID: 22630061Free PMC Article
Clinical utility of spine bone density in elderly women.
Schneider DL, Bettencourt R, Barrett-Connor E
J Clin Densitom 2006 Jul-Sep;9(3):255-60. doi: 10.1016/j.jocd.2006.04.116. PMID: 16931341Free PMC Article

Recent clinical studies

Etiology

Association between clinical findings and the presence of lumbar spine osteoarthritis imaging features: A systematic review.
Chamoro M, de Luca K, Ozbulut O, Oei EHG, Vleggeert-Lankamp CLA, Koes BW, Bierma-Zeinstra SMA, Chiarotto A
Osteoarthritis Cartilage 2023 Sep;31(9):1158-1175. Epub 2023 May 6 doi: 10.1016/j.joca.2023.04.014. PMID: 37150286
Association between sleep duration and osteoarthritis and their prevalence in Koreans: A cross-sectional study.
Cho Y, Jung B, Lee YJ, Kim MR, Kim EJ, Sung WS, Ha IH
PLoS One 2020;15(4):e0230481. Epub 2020 Apr 27 doi: 10.1371/journal.pone.0230481. PMID: 32339178Free PMC Article
PNF and manual therapy treatment results of patients with cervical spine osteoarthritis.
Maicki T, Bilski J, Szczygieł E, Trąbka R
J Back Musculoskelet Rehabil 2017 Sep 22;30(5):1095-1101. doi: 10.3233/BMR-169718. PMID: 28946528Free PMC Article
Osteoarthritis and joint replacements of the lower limb and spine in ex-professional soccer players: A systematic review.
Lohkamp M, Kromer TO, Schmitt H
Scand J Med Sci Sports 2017 Oct;27(10):1038-1049. Epub 2017 Mar 29 doi: 10.1111/sms.12846. PMID: 28150871
Low back pain and lumbar spine osteoarthritis: how are they related?
Goode AP, Carey TS, Jordan JM
Curr Rheumatol Rep 2013 Feb;15(2):305. doi: 10.1007/s11926-012-0305-z. PMID: 23307577Free PMC Article

Diagnosis

Cervical spinal gout.
Jeong W, Yoo JR
Lancet Rheumatol 2023 Jul;5(7):e426. Epub 2022 Nov 2 doi: 10.1016/S2665-9913(22)00306-X. PMID: 38251554
Association between clinical findings and the presence of lumbar spine osteoarthritis imaging features: A systematic review.
Chamoro M, de Luca K, Ozbulut O, Oei EHG, Vleggeert-Lankamp CLA, Koes BW, Bierma-Zeinstra SMA, Chiarotto A
Osteoarthritis Cartilage 2023 Sep;31(9):1158-1175. Epub 2023 May 6 doi: 10.1016/j.joca.2023.04.014. PMID: 37150286
PNF and manual therapy treatment results of patients with cervical spine osteoarthritis.
Maicki T, Bilski J, Szczygieł E, Trąbka R
J Back Musculoskelet Rehabil 2017 Sep 22;30(5):1095-1101. doi: 10.3233/BMR-169718. PMID: 28946528Free PMC Article
Osteoarthritis and joint replacements of the lower limb and spine in ex-professional soccer players: A systematic review.
Lohkamp M, Kromer TO, Schmitt H
Scand J Med Sci Sports 2017 Oct;27(10):1038-1049. Epub 2017 Mar 29 doi: 10.1111/sms.12846. PMID: 28150871
Spine osteoarthritis.
Laplante BL, DePalma MJ
PM R 2012 May;4(5 Suppl):S28-36. doi: 10.1016/j.pmrj.2012.03.005. PMID: 22632699

Therapy

Effects of complex spa therapy in patients with osteoarthritis of the spine receiving treatments in health resorts in south-eastern Poland.
Zwolińska J, Gąsior M
Sci Rep 2022 Aug 29;12(1):14663. doi: 10.1038/s41598-022-18046-6. PMID: 36038633Free PMC Article
Efficiency of proteolytic enzymes in treating lumbar spine osteoarthritis (low back pain) patients and its effects on liver and kidney enzymes.
Naeem H, Naqvi SN, Perveen R, Ishaque F, Bano R, Abrar H, Arsalan A, Malik N
Pak J Pharm Sci 2020 Jan;33(1(Supplementary)):371-378. PMID: 32122870
Relationship of joint hypermobility with low Back pain and lumbar spine osteoarthritis.
Goode AP, Cleveland RJ, Schwartz TA, Nelson AE, Kraus VB, Hillstrom HJ, Hannan MT, Flowers P, Renner JB, Jordan JM, Golightly YM
BMC Musculoskelet Disord 2019 Apr 9;20(1):158. doi: 10.1186/s12891-019-2523-2. PMID: 30967130Free PMC Article
Relationship between hormone replacement therapy and spinal osteoarthritis: a nationwide health survey analysis of the elderly Korean population.
Park JH, Hong JY, Han K, Han SW, Chun EM
BMJ Open 2017 Nov 9;7(11):e018063. doi: 10.1136/bmjopen-2017-018063. PMID: 29127229Free PMC Article
PNF and manual therapy treatment results of patients with cervical spine osteoarthritis.
Maicki T, Bilski J, Szczygieł E, Trąbka R
J Back Musculoskelet Rehabil 2017 Sep 22;30(5):1095-1101. doi: 10.3233/BMR-169718. PMID: 28946528Free PMC Article

Prognosis

Predictors of Lumbar Spine Degeneration and Low Back Pain in the Community: The Johnston County Osteoarthritis Project.
Goode AP, Cleveland RJ, George SZ, Schwartz TA, Kraus VB, Renner JB, Gracely RH, DeFrate LE, Hu D, Jordan JM, Golightly YM
Arthritis Care Res (Hoboken) 2022 Oct;74(10):1659-1666. Epub 2022 Jun 28 doi: 10.1002/acr.24643. PMID: 33973412Free PMC Article
Clinical and radiographic features of spinal osteoarthritis predict long-term persistence and severity of back pain in older adults.
van den Berg R, Chiarotto A, Enthoven WT, de Schepper E, Oei EHG, Koes BW, Bierma-Zeinstra SMA
Ann Phys Rehabil Med 2022 Jan;65(1):101427. Epub 2020 Aug 27 doi: 10.1016/j.rehab.2020.07.010. PMID: 32798770
Association between sleep duration and osteoarthritis and their prevalence in Koreans: A cross-sectional study.
Cho Y, Jung B, Lee YJ, Kim MR, Kim EJ, Sung WS, Ha IH
PLoS One 2020;15(4):e0230481. Epub 2020 Apr 27 doi: 10.1371/journal.pone.0230481. PMID: 32339178Free PMC Article
PNF and manual therapy treatment results of patients with cervical spine osteoarthritis.
Maicki T, Bilski J, Szczygieł E, Trąbka R
J Back Musculoskelet Rehabil 2017 Sep 22;30(5):1095-1101. doi: 10.3233/BMR-169718. PMID: 28946528Free PMC Article
Hip-spine syndrome: A cadaveric analysis between osteoarthritis of the lumbar spine and hip joints.
Weinberg DS, Gebhart JJ, Liu RW
Orthop Traumatol Surg Res 2017 Sep;103(5):651-656. Epub 2017 May 31 doi: 10.1016/j.otsr.2017.05.010. PMID: 28578098

Clinical prediction guides

Association between clinical findings and the presence of lumbar spine osteoarthritis imaging features: A systematic review.
Chamoro M, de Luca K, Ozbulut O, Oei EHG, Vleggeert-Lankamp CLA, Koes BW, Bierma-Zeinstra SMA, Chiarotto A
Osteoarthritis Cartilage 2023 Sep;31(9):1158-1175. Epub 2023 May 6 doi: 10.1016/j.joca.2023.04.014. PMID: 37150286
Are serum thyroid hormone, parathormone, calcium, and vitamin D levels associated with lumbar spine degeneration? A cross-sectional observational clinical study.
Ekşi MŞ, Orhun Ö, Demir YN, Kara M, Berikol G, Özcan-Ekşi EE
Eur Spine J 2023 May;32(5):1561-1574. Epub 2023 Mar 28 doi: 10.1007/s00586-023-07673-w. PMID: 36976340
Clinical and radiographic features of spinal osteoarthritis predict long-term persistence and severity of back pain in older adults.
van den Berg R, Chiarotto A, Enthoven WT, de Schepper E, Oei EHG, Koes BW, Bierma-Zeinstra SMA
Ann Phys Rehabil Med 2022 Jan;65(1):101427. Epub 2020 Aug 27 doi: 10.1016/j.rehab.2020.07.010. PMID: 32798770
Association between sleep duration and osteoarthritis and their prevalence in Koreans: A cross-sectional study.
Cho Y, Jung B, Lee YJ, Kim MR, Kim EJ, Sung WS, Ha IH
PLoS One 2020;15(4):e0230481. Epub 2020 Apr 27 doi: 10.1371/journal.pone.0230481. PMID: 32339178Free PMC Article
TBS result is not affected by lumbar spine osteoarthritis.
Kolta S, Briot K, Fechtenbaum J, Paternotte S, Armbrecht G, Felsenberg D, Glüer CC, Eastell R, Roux C
Osteoporos Int 2014 Jun;25(6):1759-64. Epub 2014 Apr 1 doi: 10.1007/s00198-014-2685-6. PMID: 24687386

Recent systematic reviews

Association between clinical findings and the presence of lumbar spine osteoarthritis imaging features: A systematic review.
Chamoro M, de Luca K, Ozbulut O, Oei EHG, Vleggeert-Lankamp CLA, Koes BW, Bierma-Zeinstra SMA, Chiarotto A
Osteoarthritis Cartilage 2023 Sep;31(9):1158-1175. Epub 2023 May 6 doi: 10.1016/j.joca.2023.04.014. PMID: 37150286
Osteoarthritis and joint replacements of the lower limb and spine in ex-professional soccer players: A systematic review.
Lohkamp M, Kromer TO, Schmitt H
Scand J Med Sci Sports 2017 Oct;27(10):1038-1049. Epub 2017 Mar 29 doi: 10.1111/sms.12846. PMID: 28150871
Prevalence of osteoarthritis in former elite athletes: a systematic overview of the recent literature.
Gouttebarge V, Inklaar H, Backx F, Kerkhoffs G
Rheumatol Int 2015 Mar;35(3):405-18. Epub 2014 Jul 19 doi: 10.1007/s00296-014-3093-0. PMID: 25037899

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...