U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Reactive arthritis

MedGen UID:
39047
•Concept ID:
C0085435
•
Disease or Syndrome
Synonyms: Reiter syndrome; Reiter's syndrome
SNOMED CT: Post-bacterial arthropathy (129133005); Reactive arthritis (201736002); Post-infective arthritis (239783001); Post-infective arthropathy (239783001); Arthritis occurring after infection (239783001)
Modes of inheritance:
Non-Mendelian inheritance
MedGen UID:
109109
•Concept ID:
C0600599
•
Genetic Function
Source: Orphanet
A mode of inheritance that depends on genetic determinants in more than one gene.
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Non-Mendelian inheritance (Orphanet)
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0017376
Orphanet: ORPHA29207

Definition

A rare spondyloarthritis characterized by acute or chronic sterile synovitis with or without extra-articular manifestations, becoming manifest after an infection. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReactive arthritis

Professional guidelines

PubMed

Reactive arthritis following COVID-19 current evidence, diagnosis, and management strategies.
Migliorini F, Bell A, Vaishya R, Eschweiler J, Hildebrand F, Maffulli N
J Orthop Surg Res 2023 Mar 15;18(1):205. doi: 10.1186/s13018-023-03651-6. PMID: 36922870Free PMC Article
Evaluation and Management of Septic Arthritis and its Mimics in the Emergency Department.
Long B, Koyfman A, Gottlieb M
West J Emerg Med 2019 Mar;20(2):331-341. Epub 2018 Dec 6 doi: 10.5811/westjem.2018.10.40974. PMID: 30881554Free PMC Article
Hepatitis A: clinical manifestations and management.
Jeong SH, Lee HS
Intervirology 2010;53(1):15-9. Epub 2010 Jan 5 doi: 10.1159/000252779. PMID: 20068336

Recent clinical studies

Etiology

Spondyloarthritides.
Taitt HA, Balakrishnan R
Immunol Allergy Clin North Am 2023 Aug;43(3):593-612. doi: 10.1016/j.iac.2022.10.001. PMID: 37394262
Reactive Arthritis Update: Spotlight on New and Rare Infectious Agents Implicated as Pathogens.
Zeidler H, Hudson AP
Curr Rheumatol Rep 2021 Jul 1;23(7):53. doi: 10.1007/s11926-021-01018-6. PMID: 34196842Free PMC Article
Understanding the Pathogenesis of Spondyloarthritis.
Sharip A, Kunz J
Biomolecules 2020 Oct 20;10(10) doi: 10.3390/biom10101461. PMID: 33092023Free PMC Article
Post-Streptococcal Reactive Arthritis.
Bawazir Y, Towheed T, Anastassiades T
Curr Rheumatol Rev 2020;16(1):2-8. doi: 10.2174/1573397115666190808110337. PMID: 31393253
Spondyloarthritis.
Dougados M, Baeten D
Lancet 2011 Jun 18;377(9783):2127-37. doi: 10.1016/S0140-6736(11)60071-8. PMID: 21684383

Diagnosis

Spondyloarthritides.
Taitt HA, Balakrishnan R
Immunol Allergy Clin North Am 2023 Aug;43(3):593-612. doi: 10.1016/j.iac.2022.10.001. PMID: 37394262
Reactive Arthritis Update: Spotlight on New and Rare Infectious Agents Implicated as Pathogens.
Zeidler H, Hudson AP
Curr Rheumatol Rep 2021 Jul 1;23(7):53. doi: 10.1007/s11926-021-01018-6. PMID: 34196842Free PMC Article
Post-Streptococcal Reactive Arthritis.
Bawazir Y, Towheed T, Anastassiades T
Curr Rheumatol Rev 2020;16(1):2-8. doi: 10.2174/1573397115666190808110337. PMID: 31393253
Reactive arthritis: update 2018.
García-Kutzbach A, Chacón-Súchite J, García-Ferrer H, Iraheta I
Clin Rheumatol 2018 Apr;37(4):869-874. Epub 2018 Feb 17 doi: 10.1007/s10067-018-4022-5. PMID: 29455267
Reactive Arthritis.
Schmitt SK
Infect Dis Clin North Am 2017 Jun;31(2):265-277. Epub 2017 Mar 11 doi: 10.1016/j.idc.2017.01.002. PMID: 28292540

Therapy

Post-Streptococcal Reactive Arthritis.
Bawazir Y, Towheed T, Anastassiades T
Curr Rheumatol Rev 2020;16(1):2-8. doi: 10.2174/1573397115666190808110337. PMID: 31393253
Evaluation and Management of Septic Arthritis and its Mimics in the Emergency Department.
Long B, Koyfman A, Gottlieb M
West J Emerg Med 2019 Mar;20(2):331-341. Epub 2018 Dec 6 doi: 10.5811/westjem.2018.10.40974. PMID: 30881554Free PMC Article
Reactive Arthritis.
Schmitt SK
Infect Dis Clin North Am 2017 Jun;31(2):265-277. Epub 2017 Mar 11 doi: 10.1016/j.idc.2017.01.002. PMID: 28292540
Traveler's Diarrhea.
Giddings SL, Stevens AM, Leung DT
Med Clin North Am 2016 Mar;100(2):317-30. doi: 10.1016/j.mcna.2015.08.017. PMID: 26900116Free PMC Article
Spondyloarthritides.
Baraliakos X, Braun J
Best Pract Res Clin Rheumatol 2011 Dec;25(6):825-42. doi: 10.1016/j.berh.2011.11.006. PMID: 22265264

Prognosis

Reactive Arthritis.
Schmitt SK
Infect Dis Clin North Am 2017 Jun;31(2):265-277. Epub 2017 Mar 11 doi: 10.1016/j.idc.2017.01.002. PMID: 28292540
Reactive arthritis.
Hannu T
Best Pract Res Clin Rheumatol 2011 Jun;25(3):347-57. doi: 10.1016/j.berh.2011.01.018. PMID: 22100285
Seronegative spondyloarthritis.
Zochling J, Smith EU
Best Pract Res Clin Rheumatol 2010 Dec;24(6):747-56. doi: 10.1016/j.berh.2011.02.002. PMID: 21665123
Hepatitis A: clinical manifestations and management.
Jeong SH, Lee HS
Intervirology 2010;53(1):15-9. Epub 2010 Jan 5 doi: 10.1159/000252779. PMID: 20068336
Reactive arthritis.
Kwiatkowska B, Filipowicz-Sosnowska A
Pol Arch Med Wewn 2009 Jan-Feb;119(1-2):60-5. PMID: 19341180

Clinical prediction guides

Reactive arthritis before and after the onset of the COVID-19 pandemic.
Bekaryssova D, Yessirkepov M, Zimba O, Gasparyan AY, Ahmed S
Clin Rheumatol 2022 Jun;41(6):1641-1652. Epub 2022 Mar 5 doi: 10.1007/s10067-022-06120-3. PMID: 35247132Free PMC Article
EULAR points to consider for the diagnosis and management of rheumatic immune-related adverse events due to cancer immunotherapy with checkpoint inhibitors.
Kostine M, Finckh A, Bingham CO, Visser K, Leipe J, Schulze-Koops H, Choy EH, Benesova K, Radstake TRDJ, Cope AP, Lambotte O, Gottenberg JE, Allenbach Y, Visser M, Rusthoven C, Thomasen L, Jamal S, Marabelle A, Larkin J, Haanen JBAG, Calabrese LH, Mariette X, Schaeverbeke T
Ann Rheum Dis 2021 Jan;80(1):36-48. Epub 2020 Apr 23 doi: 10.1136/annrheumdis-2020-217139. PMID: 32327425Free PMC Article
Hepatitis A: clinical manifestations and management.
Jeong SH, Lee HS
Intervirology 2010;53(1):15-9. Epub 2010 Jan 5 doi: 10.1159/000252779. PMID: 20068336
Synovitis score: discrimination between chronic low-grade and high-grade synovitis.
Krenn V, Morawietz L, Burmester GR, Kinne RW, Mueller-Ladner U, Muller B, Haupl T
Histopathology 2006 Oct;49(4):358-64. doi: 10.1111/j.1365-2559.2006.02508.x. PMID: 16978198
Reactive arthritis.
Toivanen A, Toivanen P
Best Pract Res Clin Rheumatol 2004 Oct;18(5):689-703. doi: 10.1016/j.berh.2004.05.008. PMID: 15454127

Recent systematic reviews

COVID-associated arthritis after severe and non-severe COVID-19: A systematic review.
Zarpoosh M, Amirian P
Immun Inflamm Dis 2023 Oct;11(10):e1035. doi: 10.1002/iid3.1035. PMID: 37904701Free PMC Article
Autoimmune disorders caused by intravesical bacillus Calmette-Guerine treatment: A systematic review.
Anis O, Yogev D, Dotan A, Tsur AM, David P, Vishnevskia Dai V, Laufer M, Dotan Z, Shoenfeld Y
Autoimmun Rev 2023 Jun;22(6):103329. Epub 2023 Apr 13 doi: 10.1016/j.autrev.2023.103329. PMID: 37061015
Reactive arthritis following COVID-19 current evidence, diagnosis, and management strategies.
Migliorini F, Bell A, Vaishya R, Eschweiler J, Hildebrand F, Maffulli N
J Orthop Surg Res 2023 Mar 15;18(1):205. doi: 10.1186/s13018-023-03651-6. PMID: 36922870Free PMC Article
Reactive Arthritis following Bacillus Calmette-Guerin Therapy for Bladder Cancer: a Systematic Literature Review.
Abdelghani KB, Nacef L, Miladi S, Sellami M, Ouenniche K, Souabni L, Kassab S, Chekili S, Fazaa A, Laatar A
Curr Rheumatol Rep 2021 Apr 28;23(6):39. doi: 10.1007/s11926-021-01004-y. PMID: 33913026
Global Prevalence of Spondyloarthritis: A Systematic Review and Meta-Regression Analysis.
Stolwijk C, van Onna M, Boonen A, van Tubergen A
Arthritis Care Res (Hoboken) 2016 Sep;68(9):1320-31. Epub 2016 Jul 27 doi: 10.1002/acr.22831. PMID: 26713432

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...