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TSH producing pituitary tumor

MedGen UID:
391700
•Concept ID:
C2362538
•
Neoplastic Process
Synonyms: thyroid stimulating hormone producing neoplasm of pituitary; thyroid stimulating hormone producing neoplasm of pituitary gland; thyroid stimulating hormone producing neoplasm of the pituitary; thyroid stimulating hormone producing neoplasm of the pituitary gland; thyroid stimulating hormone producing pituitary gland neoplasm; thyroid stimulating hormone producing pituitary gland tumor; thyroid stimulating hormone producing pituitary gland tumour; thyroid stimulating hormone producing pituitary neoplasm; thyroid stimulating hormone producing pituitary tumor; thyroid stimulating hormone producing pituitary tumour; thyroid stimulating hormone producing tumor; thyroid stimulating hormone producing tumor of pituitary; thyroid stimulating hormone producing tumor of pituitary gland; thyroid stimulating hormone producing tumor of the pituitary; thyroid stimulating hormone producing tumor of the pituitary gland; thyroid stimulating hormone producing tumour; thyroid stimulating hormone producing tumour of pituitary; thyroid stimulating hormone producing tumour of pituitary gland; thyroid stimulating hormone producing tumour of the pituitary; thyroid stimulating hormone producing tumour of the pituitary gland; thyroid stimulating hormone secreting neoplasm of pituitary; thyroid stimulating hormone secreting neoplasm of pituitary gland; thyroid stimulating hormone secreting neoplasm of the pituitary; thyroid stimulating hormone secreting neoplasm of the pituitary gland; thyroid stimulating hormone secreting pituitary gland neoplasm; thyroid stimulating hormone secreting pituitary gland tumor; thyroid stimulating hormone secreting pituitary gland tumour; thyroid stimulating hormone secreting pituitary neoplasm; thyroid stimulating hormone secreting pituitary tumor; thyroid stimulating hormone secreting pituitary tumour; thyroid stimulating hormone secreting tumor of pituitary; thyroid stimulating hormone secreting tumor of pituitary gland; thyroid stimulating hormone secreting tumor of the pituitary; thyroid stimulating hormone secreting tumor of the pituitary gland; thyroid stimulating hormone secreting tumour of pituitary; thyroid stimulating hormone secreting tumour of pituitary gland; thyroid stimulating hormone secreting tumour of the pituitary; thyroid stimulating hormone secreting tumour of the pituitary gland; thyrotropin producing pituitary gland neoplasm; thyrotropin-secreting pituitary adenoma; TSH producing neoplasm of pituitary; TSH producing neoplasm of pituitary gland; TSH producing neoplasm of the pituitary; TSH producing neoplasm of the pituitary gland; TSH producing pituitary gland neoplasm; TSH producing pituitary gland tumor; TSH producing pituitary gland tumour; TSH producing pituitary neoplasm; TSH producing tumor of pituitary; TSH producing tumor of pituitary gland; TSH producing tumor of the pituitary; TSH producing tumor of the pituitary gland; TSH producing tumour of pituitary; TSH producing tumour of pituitary gland; TSH producing tumour of the pituitary; TSH producing tumour of the pituitary gland; TSH secreting neoplasm of pituitary; TSH secreting neoplasm of pituitary gland; TSH secreting neoplasm of the pituitary; TSH secreting neoplasm of the pituitary gland; TSH secreting pituitary gland neoplasm; TSH secreting pituitary gland tumor; TSH secreting pituitary gland tumour; TSH secreting pituitary neoplasm; TSH secreting pituitary tumor; TSH secreting pituitary tumour; TSH secreting tumor of pituitary; TSH secreting tumor of pituitary gland; TSH secreting tumor of the pituitary; TSH secreting tumor of the pituitary gland; TSH secreting tumour of pituitary; TSH secreting tumour of pituitary gland; TSH secreting tumour of the pituitary; TSH secreting tumour of the pituitary gland; TSH-oma; TSH-producing pituitary gland neoplasm; TSH-producing pituitary gland tumor; TSH-producing pituitary gland tumour
 
Monarch Initiative: MONDO:0003837

Definition

An adenoma or carcinoma of the anterior lobe of the pituitary gland that produces thyrotropin. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTSH producing pituitary tumor

Professional guidelines

PubMed

Surgical treatment and outcome of TSH-producing pituitary adenomas.
Rotermund R, Riedel N, Burkhardt T, Matschke J, Schmidt NO, Aberle J, Flitsch J
Acta Neurochir (Wien) 2017 Jul;159(7):1219-1226. Epub 2017 Feb 15 doi: 10.1007/s00701-017-3105-4. PMID: 28204898
Pituitary tumor management in pregnancy.
Araujo PB, Vieira Neto L, Gadelha MR
Endocrinol Metab Clin North Am 2015 Mar;44(1):181-97. Epub 2014 Nov 4 doi: 10.1016/j.ecl.2014.10.015. PMID: 25732654
Pituitary tumors: diagnosis and treatment.
Croughs RJ
Anticancer Drugs 1992 Dec;3(6):555-65. doi: 10.1097/00001813-199212000-00001. PMID: 1288725

Recent clinical studies

Etiology

Circadian and pulsatile TSH secretion under physiological and pathophysiological conditions.
Brabant G, Prank K, Ranft U, Bergmann P, Schuermeyer T, Hesch RD, von zur Mühlen A
Horm Metab Res Suppl 1990;23:12-7. PMID: 2210627

Diagnosis

Concomitant Graves hyperthyroidism with thyrotrophin-secreting pituitary adenoma.
Lee MT, Wang CY
South Med J 2010 Apr;103(4):347-9. doi: 10.1097/SMJ.0b013e3181d3ce93. PMID: 20224487
A plurihormonal TSH-producing pituitary tumor of monoclonal origin in a patient with hypothyroidism.
Ma W, Ikeda H, Watabe N, Kanno M, Yoshimoto T
Horm Res 2003;59(5):257-61. doi: 10.1159/000070227. PMID: 12714791
TSH producing pituitary tumor: biochemical diagnosis and long-term medical management with octreotide.
Chayen SD, Gross D, Makhoul O, Glaser B
Horm Metab Res 1992 Jan;24(1):34-8. doi: 10.1055/s-2007-1003247. PMID: 1612557

Therapy

TSH producing pituitary tumor: biochemical diagnosis and long-term medical management with octreotide.
Chayen SD, Gross D, Makhoul O, Glaser B
Horm Metab Res 1992 Jan;24(1):34-8. doi: 10.1055/s-2007-1003247. PMID: 1612557
Effect of a long-acting somatostatin analogue (SMS 201-995) on a growth hormone and thyroid stimulating hormone-producing pituitary tumor.
Hirasawa R, Hashimoto K, Makino S, Suemaru S, Takao T, Ota Z, Hoshida Y, Yoshino T, Akagi T
Acta Med Okayama 1991 Apr;45(2):107-15. doi: 10.18926/AMO/32184. PMID: 1867112

Prognosis

Concomitant Graves hyperthyroidism with thyrotrophin-secreting pituitary adenoma.
Lee MT, Wang CY
South Med J 2010 Apr;103(4):347-9. doi: 10.1097/SMJ.0b013e3181d3ce93. PMID: 20224487

Clinical prediction guides

Heterogeneity of human luteinizing hormone in pituitary tumor homogenates and cell incubates.
van Ginkel LA, Somers HH, Loeber JG
J Endocrinol Invest 1995 Apr;18(4):258-64. doi: 10.1007/BF03347810. PMID: 7560806
TSH producing pituitary tumor: biochemical diagnosis and long-term medical management with octreotide.
Chayen SD, Gross D, Makhoul O, Glaser B
Horm Metab Res 1992 Jan;24(1):34-8. doi: 10.1055/s-2007-1003247. PMID: 1612557

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