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Benign carotid body paraganglioma

MedGen UID:
396868
•Concept ID:
C2698359
•
Neoplastic Process
Synonyms: Benign Carotid Body Paraganglioma; benign carotid body paraganglioma; Benign Chemodectoma; benign chemodectoma; carotid body paraganglioma, benign; chemodectoma, benign; Non-Metastatic Carotid Body Paraganglioma
 
Monarch Initiative: MONDO:0006104

Definition

A paraganglioma that arises from and is confined to the carotid body. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign carotid body paraganglioma

Professional guidelines

PubMed

Treatment of Head and Neck Paragangliomas.
Hu K, Persky MS
Cancer Control 2016 Jul;23(3):228-41. doi: 10.1177/107327481602300306. PMID: 27556663
Diagnosis and management of multiple paragangliomas of the head and neck.
Szymańska A, Szymański M, Czekajska-Chehab E, Gołąbek W, Szczerbo-Trojanowska M
Eur Arch Otorhinolaryngol 2015 Aug;272(8):1991-9. Epub 2014 Jun 12 doi: 10.1007/s00405-014-3126-z. PMID: 24920325Free PMC Article
Paragangliomas of the head and neck: diagnosis and treatment.
Boedeker CC, Ridder GJ, Schipper J
Fam Cancer 2005;4(1):55-9. doi: 10.1007/s10689-004-2154-z. PMID: 15883711

Recent clinical studies

Etiology

Long-Term Outcomes of Patients With Carotid and Aortic Body Tumors.
Verghis NM, Brown JA, Yousef S, Aranda-Michel E, Serna-Gallegos D, Levenson J, Ogami T, Diaz-Castrillon C, Thoma F, Singh M, Sultan I
Am J Cardiol 2023 Jul 15;199:78-84. Epub 2023 May 31 doi: 10.1016/j.amjcard.2023.05.003. PMID: 37262989
Surgical outcomes and factors associated with malignancy in carotid body tumors.
Zhang W, Liu F, Hou K, Shu X, Chen B, Wang L, Guo D, Fu W
J Vasc Surg 2021 Aug;74(2):586-591. Epub 2021 Feb 4 doi: 10.1016/j.jvs.2020.12.097. PMID: 33548423
Simple and complex carotid paragangliomas. Three decades of experience and literature review.
Lozano FS, Muñoz A, de Las Heras JA, González-Porras JR
Head Neck 2020 Dec;42(12):3538-3550. Epub 2020 Aug 19 doi: 10.1002/hed.26421. PMID: 32812684
Carotid Body Tumors: A Case Series and Review of the Literature.
Darouassi Y, Alaoui M, Mliha Touati M, Al Maghraoui O, En-Nouali A, Bouaity B, Ammar H
Ann Vasc Surg 2017 Aug;43:265-271. Epub 2017 May 3 doi: 10.1016/j.avsg.2017.03.167. PMID: 28478173
Etiopathogenesis and clinical presentation of carotid body tumors.
Baysal BE, Myers EN
Microsc Res Tech 2002 Nov 1;59(3):256-61. doi: 10.1002/jemt.10200. PMID: 12384970

Diagnosis

Simple and complex carotid paragangliomas. Three decades of experience and literature review.
Lozano FS, Muñoz A, de Las Heras JA, González-Porras JR
Head Neck 2020 Dec;42(12):3538-3550. Epub 2020 Aug 19 doi: 10.1002/hed.26421. PMID: 32812684
Acquired Vascular Tumors of the Head and Neck.
Persky M, Tran T
Otolaryngol Clin North Am 2018 Feb;51(1):255-274. Epub 2017 Oct 27 doi: 10.1016/j.otc.2017.09.015. PMID: 29106888
Carotid Body Tumors: A Case Series and Review of the Literature.
Darouassi Y, Alaoui M, Mliha Touati M, Al Maghraoui O, En-Nouali A, Bouaity B, Ammar H
Ann Vasc Surg 2017 Aug;43:265-271. Epub 2017 May 3 doi: 10.1016/j.avsg.2017.03.167. PMID: 28478173
Carotid body paraganglioma.
Manzoor T, Ahmed B, Najam A, Ayub Z
J Coll Physicians Surg Pak 2009 Aug;19(8):523-5. PMID: 19651019
Paragangliomas of the head and neck: diagnosis and treatment.
Boedeker CC, Ridder GJ, Schipper J
Fam Cancer 2005;4(1):55-9. doi: 10.1007/s10689-004-2154-z. PMID: 15883711

Therapy

Preoperative Embolization Of Carotid Body Tumours: Yes Or No?
Soares T, Dias P, Sampaio S, Teixeira J
Port J Card Thorac Vasc Surg 2023 Jan 14;29(4):27-30. doi: 10.48729/pjctvs.206. PMID: 36640293
Surgical outcomes and factors associated with malignancy in carotid body tumors.
Zhang W, Liu F, Hou K, Shu X, Chen B, Wang L, Guo D, Fu W
J Vasc Surg 2021 Aug;74(2):586-591. Epub 2021 Feb 4 doi: 10.1016/j.jvs.2020.12.097. PMID: 33548423
Carotid body tumor: a 25-year experience.
Metheetrairut C, Chotikavanich C, Keskool P, Suphaphongs N
Eur Arch Otorhinolaryngol 2016 Aug;273(8):2171-9. Epub 2015 Aug 2 doi: 10.1007/s00405-015-3737-z. PMID: 26233244
Management of carotid body tumors and familial paragangliomas: review of 30 years' experience.
Unlü Y, Becit N, Ceviz M, Koçak H
Ann Vasc Surg 2009 Sep-Oct;23(5):616-20. doi: 10.1016/j.avsg.2009.06.014. PMID: 19747612
Carotid body tumors.
Dent TL, Thompson NW, Fry WJ
Surgery 1976 Sep;80(3):365-72. PMID: 960003

Prognosis

Treatment of relapses of benign latero-cervical pathology: a narrative literature review.
Meliante PG, Colizza A, Ralli M, Minni A, Angeletti D, Cambria F, de Vincentiis M
Acta Otorhinolaryngol Ital 2023 Apr;43(Suppl 1):S76-S83. doi: 10.14639/0392-100X-suppl.1-43-2023-10. PMID: 37698104Free PMC Article
Surgical outcomes and factors associated with malignancy in carotid body tumors.
Zhang W, Liu F, Hou K, Shu X, Chen B, Wang L, Guo D, Fu W
J Vasc Surg 2021 Aug;74(2):586-591. Epub 2021 Feb 4 doi: 10.1016/j.jvs.2020.12.097. PMID: 33548423
Distinct features of malignant carotid body tumors and surgical techniques for challengeable lesions: a case series of 11 patients.
Gu G, Wang Y, Liu B, Chen Y, Shao J, Li F, Wu X, Cui L, Lu X, Liu C, Guan H, Gao Z, Feng G, Zheng Y
Eur Arch Otorhinolaryngol 2020 Mar;277(3):853-861. Epub 2019 Dec 5 doi: 10.1007/s00405-019-05740-x. PMID: 31807890
Carotid Body Tumors: A Case Series and Review of the Literature.
Darouassi Y, Alaoui M, Mliha Touati M, Al Maghraoui O, En-Nouali A, Bouaity B, Ammar H
Ann Vasc Surg 2017 Aug;43:265-271. Epub 2017 May 3 doi: 10.1016/j.avsg.2017.03.167. PMID: 28478173
Management of carotid body tumors and familial paragangliomas: review of 30 years' experience.
Unlü Y, Becit N, Ceviz M, Koçak H
Ann Vasc Surg 2009 Sep-Oct;23(5):616-20. doi: 10.1016/j.avsg.2009.06.014. PMID: 19747612

Clinical prediction guides

Treatment of relapses of benign latero-cervical pathology: a narrative literature review.
Meliante PG, Colizza A, Ralli M, Minni A, Angeletti D, Cambria F, de Vincentiis M
Acta Otorhinolaryngol Ital 2023 Apr;43(Suppl 1):S76-S83. doi: 10.14639/0392-100X-suppl.1-43-2023-10. PMID: 37698104Free PMC Article
Carotid Body Tumors: A Case Series and Review of the Literature.
Darouassi Y, Alaoui M, Mliha Touati M, Al Maghraoui O, En-Nouali A, Bouaity B, Ammar H
Ann Vasc Surg 2017 Aug;43:265-271. Epub 2017 May 3 doi: 10.1016/j.avsg.2017.03.167. PMID: 28478173
Carotid body paragangliomas and matrix metalloproteinases.
Serra R, Grande R, Gallelli L, Rende P, Scarcello E, Buffone G, Caliò FG, Gasbarro V, Amato B, de Franciscis S
Ann Vasc Surg 2014 Oct;28(7):1665-70. Epub 2014 Apr 2 doi: 10.1016/j.avsg.2014.03.022. PMID: 24704048
Clinical, histopathologic, and radiographic indicators of malignancy in head and neck paragangliomas.
Chapman DB, Lippert D, Geer CP, Edwards HD, Russell GB, Rees CJ, Browne JD
Otolaryngol Head Neck Surg 2010 Oct;143(4):531-7. Epub 2010 Aug 16 doi: 10.1016/j.otohns.2010.05.031. PMID: 20869564
Management of carotid body tumors and familial paragangliomas: review of 30 years' experience.
Unlü Y, Becit N, Ceviz M, Koçak H
Ann Vasc Surg 2009 Sep-Oct;23(5):616-20. doi: 10.1016/j.avsg.2009.06.014. PMID: 19747612

Recent systematic reviews

Stereotactic radiosurgery for head and neck paragangliomas: a systematic review and meta-analysis.
Fatima N, Pollom E, Soltys S, Chang SD, Meola A
Neurosurg Rev 2021 Apr;44(2):741-752. Epub 2020 Apr 21 doi: 10.1007/s10143-020-01292-5. PMID: 32318920
Ancient schwannoma mimicking a carotid body tumor A case report and review of the literature.
Garbuglio R, Turchino D, Giribono AM, Viviani E, Ferrante L, Sodo M, Del Guercio L, Bracale UM
Ann Ital Chir 2020 Jan 20;9 PMID: 31957705

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