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B lymphoblastic leukemia lymphoma with hyperdiploidy

MedGen UID:
397154
Concept ID:
C2698311
Neoplastic Process
Synonyms: B Lymphoblastic Leukemia/Lymphoma with Hyperdiploidy; B-Lymphoblastic Leukemia/Lymphoma with Hyperdiploidy; B-lymphoblastic leukemia/lymphoma with hyperdiploidy
SNOMED CT: B lymphoblastic leukemia lymphoma with hyperdiploidy (450953000); B lymphoblastic leukemia lymphoma with hyperdiploidy (838346000)
 
Monarch Initiative: MONDO:0035943
Orphanet: ORPHA585936

Definition

A precursor lymphoid neoplasm composed of B-lymphoblasts which contain more than 50 and usually less than 66 chromosomes. It has a favorable clinical outcome. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • B lymphoblastic leukemia lymphoma with hyperdiploidy

Professional guidelines

PubMed

Malecka A, Hennig M, Jaworski R, Irga-Jaworska N
J Pediatr Hematol Oncol 2023 Jan 1;45(1):e4-e8. Epub 2022 Oct 19 doi: 10.1097/MPH.0000000000002579. PMID: 36598962
Al-Sudairy R, Al-Nasser A, Alsultan A, Al Ahmari A, Abosoudah I, Al-Hayek R, Al-Harbi T, Al-Manjomi F, Al-Harbi M, Al-Ghamdi H, Al-Shahrani M, Belgaumi AF
Pediatr Blood Cancer 2014 Jan;61(1):74-80. Epub 2013 Aug 12 doi: 10.1002/pbc.24584. PMID: 23940019
Gaynon PS
Hematol Oncol Clin North Am 1990 Oct;4(5):915-36. PMID: 2262485

Recent clinical studies

Etiology

Lee SHR, Ashcraft E, Yang W, Roberts KG, Gocho Y, Rowland L, Inaba H, Karol SE, Jeha S, Crews KR, Mullighan CG, Relling MV, Evans WE, Cheng C, Yang JJ, Pui CH
J Clin Oncol 2023 Dec 10;41(35):5422-5432. Epub 2023 Sep 20 doi: 10.1200/JCO.23.00880. PMID: 37729596Free PMC Article
Davis K, Sheikh T, Aggarwal N
Semin Diagn Pathol 2023 May;40(3):202-215. Epub 2023 Apr 9 doi: 10.1053/j.semdp.2023.04.003. PMID: 37120350
Chen Z, Sun Y, Xie W, Wang SA, Hu S, Li S, Tang Z, Toruner G, Medeiros LJ, Tang G
Cancer Med 2019 Aug;8(9):4093-4099. Epub 2019 Jun 7 doi: 10.1002/cam4.2255. PMID: 31173486Free PMC Article
Teachey DT, Pui CH
Lancet Oncol 2019 Mar;20(3):e142-e154. doi: 10.1016/S1470-2045(19)30031-2. PMID: 30842058Free PMC Article
Li JF, Dai YT, Lilljebjörn H, Shen SH, Cui BW, Bai L, Liu YF, Qian MX, Kubota Y, Kiyoi H, Matsumura I, Miyazaki Y, Olsson L, Tan AM, Ariffin H, Chen J, Takita J, Yasuda T, Mano H, Johansson B, Yang JJ, Yeoh AE, Hayakawa F, Chen Z, Pui CH, Fioretos T, Chen SJ, Huang JY
Proc Natl Acad Sci U S A 2018 Dec 11;115(50):E11711-E11720. Epub 2018 Nov 28 doi: 10.1073/pnas.1814397115. PMID: 30487223Free PMC Article

Diagnosis

Lee SHR, Ashcraft E, Yang W, Roberts KG, Gocho Y, Rowland L, Inaba H, Karol SE, Jeha S, Crews KR, Mullighan CG, Relling MV, Evans WE, Cheng C, Yang JJ, Pui CH
J Clin Oncol 2023 Dec 10;41(35):5422-5432. Epub 2023 Sep 20 doi: 10.1200/JCO.23.00880. PMID: 37729596Free PMC Article
Panuciak K, Nowicka E, Mastalerczyk A, Zawitkowska J, Niedźwiecki M, Lejman M
Int J Mol Sci 2023 May 15;24(10) doi: 10.3390/ijms24108764. PMID: 37240110Free PMC Article
Davis K, Sheikh T, Aggarwal N
Semin Diagn Pathol 2023 May;40(3):202-215. Epub 2023 Apr 9 doi: 10.1053/j.semdp.2023.04.003. PMID: 37120350
Bomken S, Enshaei A, Schwalbe EC, Mikulasova A, Dai Y, Zaka M, Fung KTM, Bashton M, Lim H, Jones L, Karataraki N, Winterman E, Ashby C, Attarbaschi A, Bertrand Y, Bradtke J, Buldini B, Burke GAA, Cazzaniga G, Gohring G, De Groot-Kruseman HA, Haferlach C, Nigro LL, Parihar M, Plesa A, Seaford E, Sonneveld E, Strehl S, Van der Velden VHJ, Rand V, Hunger SP, Harrison CJ, Bacon CM, Van Delft FW, Loh ML, Moppett J, Vormoor J, Walker BA, Moorman AV, Russell LJ
Haematologica 2023 Mar 1;108(3):717-731. doi: 10.3324/haematol.2021.280557. PMID: 35484682Free PMC Article
Li JF, Dai YT, Lilljebjörn H, Shen SH, Cui BW, Bai L, Liu YF, Qian MX, Kubota Y, Kiyoi H, Matsumura I, Miyazaki Y, Olsson L, Tan AM, Ariffin H, Chen J, Takita J, Yasuda T, Mano H, Johansson B, Yang JJ, Yeoh AE, Hayakawa F, Chen Z, Pui CH, Fioretos T, Chen SJ, Huang JY
Proc Natl Acad Sci U S A 2018 Dec 11;115(50):E11711-E11720. Epub 2018 Nov 28 doi: 10.1073/pnas.1814397115. PMID: 30487223Free PMC Article

Therapy

Lee SHR, Ashcraft E, Yang W, Roberts KG, Gocho Y, Rowland L, Inaba H, Karol SE, Jeha S, Crews KR, Mullighan CG, Relling MV, Evans WE, Cheng C, Yang JJ, Pui CH
J Clin Oncol 2023 Dec 10;41(35):5422-5432. Epub 2023 Sep 20 doi: 10.1200/JCO.23.00880. PMID: 37729596Free PMC Article
Bomken S, Enshaei A, Schwalbe EC, Mikulasova A, Dai Y, Zaka M, Fung KTM, Bashton M, Lim H, Jones L, Karataraki N, Winterman E, Ashby C, Attarbaschi A, Bertrand Y, Bradtke J, Buldini B, Burke GAA, Cazzaniga G, Gohring G, De Groot-Kruseman HA, Haferlach C, Nigro LL, Parihar M, Plesa A, Seaford E, Sonneveld E, Strehl S, Van der Velden VHJ, Rand V, Hunger SP, Harrison CJ, Bacon CM, Van Delft FW, Loh ML, Moppett J, Vormoor J, Walker BA, Moorman AV, Russell LJ
Haematologica 2023 Mar 1;108(3):717-731. doi: 10.3324/haematol.2021.280557. PMID: 35484682Free PMC Article
Teachey DT, Pui CH
Lancet Oncol 2019 Mar;20(3):e142-e154. doi: 10.1016/S1470-2045(19)30031-2. PMID: 30842058Free PMC Article
Yen HJ, Chen SH, Chang TY, Yang CP, Lin DT, Hung IJ, Lin KH, Chen JS, Hsiao CC, Chang TT, Chang TK, Peng CT, Lin MT, Jaing TH, Liu HC, Jou ST, Lu MY, Cheng CN, Sheen JM, Chiou SS, Hung GY, Wu KH, Yeh TC, Wang SC, Chen RL, Chang HH, Yang YL, Chen SH, Cheng SN, Chang YH, Chen BW, Hsieh YL, Huang FL, Ho WL, Wang JL, Chang CY, Chao YH, Lin PC, Chen YC, Liao YM, Lin TH, Shih LY, Liang DC
Pediatr Blood Cancer 2017 Oct;64(10) Epub 2017 Apr 24 doi: 10.1002/pbc.26557. PMID: 28436581
Moorman AV
Haematologica 2016 Apr;101(4):407-16. doi: 10.3324/haematol.2015.141101. PMID: 27033238Free PMC Article

Prognosis

Lee SHR, Ashcraft E, Yang W, Roberts KG, Gocho Y, Rowland L, Inaba H, Karol SE, Jeha S, Crews KR, Mullighan CG, Relling MV, Evans WE, Cheng C, Yang JJ, Pui CH
J Clin Oncol 2023 Dec 10;41(35):5422-5432. Epub 2023 Sep 20 doi: 10.1200/JCO.23.00880. PMID: 37729596Free PMC Article
Panuciak K, Nowicka E, Mastalerczyk A, Zawitkowska J, Niedźwiecki M, Lejman M
Int J Mol Sci 2023 May 15;24(10) doi: 10.3390/ijms24108764. PMID: 37240110Free PMC Article
Haas OA, Borkhardt A
Leukemia 2022 Dec;36(12):2769-2783. Epub 2022 Oct 20 doi: 10.1038/s41375-022-01720-z. PMID: 36266323Free PMC Article
Chen Z, Sun Y, Xie W, Wang SA, Hu S, Li S, Tang Z, Toruner G, Medeiros LJ, Tang G
Cancer Med 2019 Aug;8(9):4093-4099. Epub 2019 Jun 7 doi: 10.1002/cam4.2255. PMID: 31173486Free PMC Article
Li JF, Dai YT, Lilljebjörn H, Shen SH, Cui BW, Bai L, Liu YF, Qian MX, Kubota Y, Kiyoi H, Matsumura I, Miyazaki Y, Olsson L, Tan AM, Ariffin H, Chen J, Takita J, Yasuda T, Mano H, Johansson B, Yang JJ, Yeoh AE, Hayakawa F, Chen Z, Pui CH, Fioretos T, Chen SJ, Huang JY
Proc Natl Acad Sci U S A 2018 Dec 11;115(50):E11711-E11720. Epub 2018 Nov 28 doi: 10.1073/pnas.1814397115. PMID: 30487223Free PMC Article

Clinical prediction guides

Niaz H, Malik HS, Mahmood R, Mehmood A, Nisar U, Jalil S
J Ayub Med Coll Abbottabad 2022 Oct-Dec;34(Suppl 1)(4):S909-S912. doi: 10.55519/JAMC-04-S4-10449. PMID: 36550642
Kulis J, Sędek Ł, Słota Ł, Perkowski B, Szczepański T
Genes (Basel) 2022 Jul 31;13(8) doi: 10.3390/genes13081374. PMID: 36011285Free PMC Article
Ramos-Muntada M, Trincado JL, Blanco J, Bueno C, Rodríguez-Cortez VC, Bataller A, López-Millán B, Schwab C, Ortega M, Velasco P, Blanco ML, Nomdedeu J, Ramírez-Orellana M, Minguela A, Fuster JL, Cuatrecasas E, Camós M, Ballerini P, Escherich G, Boer J, DenBoer M, Hernández-Rivas JM, Calasanz MJ, Cazzaniga G, Harrison CJ, Menéndez P, Molina O
Mol Oncol 2022 Aug;16(16):2899-2919. Epub 2022 Jul 19 doi: 10.1002/1878-0261.13276. PMID: 35726693Free PMC Article
Klairmont MM, Zhou Y, Cheng C, Pui CH, Jeha S, Gruber TA, Liu Y, Inaba H, Choi JK
Mod Pathol 2021 Nov;34(11):2050-2054. Epub 2021 Jun 19 doi: 10.1038/s41379-021-00853-3. PMID: 34148065Free PMC Article
Moorman AV
Haematologica 2016 Apr;101(4):407-16. doi: 10.3324/haematol.2015.141101. PMID: 27033238Free PMC Article

Recent systematic reviews

Illarregi U, Telleria J, Bilbao-Aldaiturriaga N, Lopez-Lopez E, Ballesteros J, Martin-Guerrero I, Gutierrez-Camino A
Int J Oncol 2022 May;60(5) Epub 2022 Apr 8 doi: 10.3892/ijo.2022.5348. PMID: 35419612

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