U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ehrlich tumor carcinoma

MedGen UID:
40103
•Concept ID:
C0007125
•
Experimental Model of Disease; Neoplastic Process
Synonyms: Ascites Tumor, Ehrlich; Carcinoma, Ehrlich Tumor; Ehrlich Ascites Tumor; Ehrlich Tumor Carcinoma; Tumor, Ehrlich Ascites
 
Monarch Initiative: MONDO:0006739

Definition

A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEhrlich tumor carcinoma

Professional guidelines

PubMed

A Promising Platform of Magnetic Nanofluid and Ultrasonic Treatment for Cancer Hyperthermia Therapy: In Vitro and in Vivo Study.
Shalaby T, Gawish A, Hamad H
Ultrasound Med Biol 2021 Mar;47(3):651-665. Epub 2021 Jan 7 doi: 10.1016/j.ultrasmedbio.2020.11.023. PMID: 33353784
Enhanced anticancer activity of combined treatment of imatinib and dipyridamole in solid Ehrlich carcinoma-bearing mice.
El-Sisi AE, Sokar SS, Ibrahim HA, Abu-Risha SE
Naunyn Schmiedebergs Arch Pharmacol 2020 Jun;393(6):1113-1129. Epub 2020 Jan 16 doi: 10.1007/s00210-019-01803-2. PMID: 31950222
Solid Ehrlich tumor growth treatment by magnetic waves.
Ali FM, El Gebaly RH, El Hag MA, Rohaim AM
Technol Health Care 2011;19(6):455-67. doi: 10.3233/THC-2011-0649. PMID: 22129946

Recent clinical studies

Etiology

Immune Stimulating Outcome of Chrysin and γ-Irradiation via Apoptotic Activation Against Solid Ehrlich Carcinoma Bearing Mice.
El Bakary NM, Alsharkawy AZ, Shouaib ZA, Barakat EMS
Integr Cancer Ther 2022 Jan-Dec;21:15347354221096668. doi: 10.1177/15347354221096668. PMID: 35543434Free PMC Article
Anticancer Effects of New Ceramides Isolated from the Red Sea Red Algae Hypnea musciformis in a Model of Ehrlich Ascites Carcinoma: LC-HRMS Analysis Profile and Molecular Modeling.
Elhady SS, Habib ES, Abdelhameed RFA, Goda MS, Hazem RM, Mehanna ET, Helal MA, Hosny KM, Diri RM, Hassanean HA, Ibrahim AK, Eltamany EE, Abdelmohsen UR, Ahmed SA
Mar Drugs 2022 Jan 10;20(1) doi: 10.3390/md20010063. PMID: 35049918Free PMC Article
The effect of antioxidants in Ehrlich Ascites Cancer.
Yılmaz S, Tokpınar A, Eroğlu E, Ateş Ş, Zahid R, Avnioğlu S, Bozkurt Ö, Nisari M
Cell Mol Biol (Noisy-le-grand) 2021 Sep 29;67(2):20-24. doi: 10.14715/cmb/2021.67.2.4. PMID: 34817342
Anti-cancer activity of two novel heterocyclic compounds through modulation of VEGFR and miR-122 in mice bearing Ehrlich ascites carcinoma.
Hazem RM, Mohamed AA, Ghareb N, Mehanna ET, Mesbah NM, Abo-Elmatty DM, Elgawish MS
Eur J Pharmacol 2021 Feb 5;892:173747. Epub 2020 Nov 21 doi: 10.1016/j.ejphar.2020.173747. PMID: 33232730
Enhanced anticancer activity of combined treatment of imatinib and dipyridamole in solid Ehrlich carcinoma-bearing mice.
El-Sisi AE, Sokar SS, Ibrahim HA, Abu-Risha SE
Naunyn Schmiedebergs Arch Pharmacol 2020 Jun;393(6):1113-1129. Epub 2020 Jan 16 doi: 10.1007/s00210-019-01803-2. PMID: 31950222

Diagnosis

Biodistribution and antitumoral effect of long-circulating and pH-sensitive liposomal cisplatin administered in Ehrlich tumor-bearing mice.
Araújo JG, Mota Ld, Leite EA, Maroni Lde C, Wainstein AJ, Coelho LG, Savassi-Rocha PR, Pereira MT, de Carvalho AT, Cardoso VN, De Oliveira MC
Exp Biol Med (Maywood) 2011 Jul;236(7):808-15. Epub 2011 Jun 17 doi: 10.1258/ebm.2011.011038. PMID: 21685237
Growth inhibition and pro-apoptotic activity of violacein in Ehrlich ascites tumor.
Bromberg N, Dreyfuss JL, Regatieri CV, Palladino MV, Durán N, Nader HB, Haun M, Justo GZ
Chem Biol Interact 2010 Jun 7;186(1):43-52. Epub 2010 Apr 21 doi: 10.1016/j.cbi.2010.04.016. PMID: 20416285
Photochemical and phototoxic activity of berberine on murine fibroblast NIH-3T3 and Ehrlich ascites carcinoma cells.
Jantová S, Letasiová S, Brezová V, Cipák L, Lábaj J
J Photochem Photobiol B 2006 Dec 1;85(3):163-76. Epub 2006 Aug 14 doi: 10.1016/j.jphotobiol.2006.07.001. PMID: 16905326
Membrane lipid composition and cellular function.
Spector AA, Yorek MA
J Lipid Res 1985 Sep;26(9):1015-35. PMID: 3906008
Na+ + K+ + 2Cl- cotransport in animal cells--its role in volume regulation.
Geck P, Pfeiffer B
Ann N Y Acad Sci 1985;456:166-82. doi: 10.1111/j.1749-6632.1985.tb14862.x. PMID: 2418724

Therapy

The effect of antioxidants in Ehrlich Ascites Cancer.
Yılmaz S, Tokpınar A, Eroğlu E, Ateş Ş, Zahid R, Avnioğlu S, Bozkurt Ö, Nisari M
Cell Mol Biol (Noisy-le-grand) 2021 Sep 29;67(2):20-24. doi: 10.14715/cmb/2021.67.2.4. PMID: 34817342
What are the immune responses during the growth of Ehrlich's tumor in ascitic and solid form?
Feitosa IB, Mori B, Teles CBG, Costa AGD
Life Sci 2021 Jan 1;264:118578. Epub 2020 Oct 13 doi: 10.1016/j.lfs.2020.118578. PMID: 33058910
Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice.
Medhat AM, Azab KS, Said MM, El Fatih NM, El Bakary NM
Tumour Biol 2017 Oct;39(10):1010428317728480. doi: 10.1177/1010428317728480. PMID: 29022496
Anticancer activity of salicin and fenofibrate.
Sabaa M, ELFayoumi HM, Elshazly S, Youns M, Barakat W
Naunyn Schmiedebergs Arch Pharmacol 2017 Oct;390(10):1061-1071. Epub 2017 Jul 21 doi: 10.1007/s00210-017-1407-y. PMID: 28733879
Anticancer activity of gallic acid template-based benzylidene indanone derivative as microtubule destabilizer.
Singh A, Fatima K, Srivastava A, Khwaja S, Priya D, Singh A, Mahajan G, Alam S, Saxena AK, Mondhe DM, Luqman S, Chanda D, Khan F, Negi AS
Chem Biol Drug Des 2016 Nov;88(5):625-634. Epub 2016 Aug 6 doi: 10.1111/cbdd.12805. PMID: 27495835

Prognosis

Nerve growth factor from cobra venom inhibits the growth of Ehrlich tumor in mice.
Osipov AV, Terpinskaya TI, Kryukova EV, Ulaschik VS, Paulovets LV, Petrova EA, Blagun EV, Starkov VG, Utkin YN
Toxins (Basel) 2014 Feb 26;6(3):784-95. doi: 10.3390/toxins6030784. PMID: 24577582Free PMC Article
Cytotoxic and antitumor effects of brucine on Ehrlich ascites tumor and human cancer cell line.
Agrawal SS, Saraswati S, Mathur R, Pandey M
Life Sci 2011 Aug 1;89(5-6):147-58. Epub 2011 Jun 13 doi: 10.1016/j.lfs.2011.05.020. PMID: 21684292
Antitumor and cytotoxic effects of Phyllanthus polyphyllus on Ehrlich ascites carcinoma and human cancer cell lines.
Rajkapoor B, Sankari M, Sumithra M, Anbu J, Harikrishnan N, Gobinath M, Suba V, Balaji R
Biosci Biotechnol Biochem 2007 Sep;71(9):2177-83. Epub 2007 Sep 7 doi: 10.1271/bbb.70149. PMID: 17827693
Induction of cytogenetic damage in human lymphocytes in vitro and of antineoplastic effects in Ehrlich ascites tumor cells in vivo treated by methotrexate, hyperthermia and/or caffeine.
Maskaleris T, Lialiaris T, Triantaphyllidis C
Mutat Res 1998 Dec 3;422(2):229-36. doi: 10.1016/s0027-5107(98)00198-5. PMID: 9838133
Membrane lipid composition and cellular function.
Spector AA, Yorek MA
J Lipid Res 1985 Sep;26(9):1015-35. PMID: 3906008

Clinical prediction guides

Anticancer Effects of New Ceramides Isolated from the Red Sea Red Algae Hypnea musciformis in a Model of Ehrlich Ascites Carcinoma: LC-HRMS Analysis Profile and Molecular Modeling.
Elhady SS, Habib ES, Abdelhameed RFA, Goda MS, Hazem RM, Mehanna ET, Helal MA, Hosny KM, Diri RM, Hassanean HA, Ibrahim AK, Eltamany EE, Abdelmohsen UR, Ahmed SA
Mar Drugs 2022 Jan 10;20(1) doi: 10.3390/md20010063. PMID: 35049918Free PMC Article
Qa-2 expression levels is related with tumor-infiltrating lymphocytes profile during solid Ehrlich tumor development.
da Silva IL, Veloso ES, Gonçalves INN, Braga AD, Lopes MTP, Cassali GD, Quintanilla M, Simões RT, Ferreira E
Biomed Pharmacother 2017 Aug;92:750-756. Epub 2017 Jun 4 doi: 10.1016/j.biopha.2017.05.135. PMID: 28591688
Eutirucallin: A Lectin with Antitumor and Antimicrobial Properties.
Palharini JG, Richter AC, Silva MF, Ferreira FB, Pirovani CP, Naves KSC, Goulart VA, Mineo TWP, Silva MJB, Santiago FM
Front Cell Infect Microbiol 2017;7:136. Epub 2017 Apr 25 doi: 10.3389/fcimb.2017.00136. PMID: 28487845Free PMC Article
Cytotoxic and antitumor effects of brucine on Ehrlich ascites tumor and human cancer cell line.
Agrawal SS, Saraswati S, Mathur R, Pandey M
Life Sci 2011 Aug 1;89(5-6):147-58. Epub 2011 Jun 13 doi: 10.1016/j.lfs.2011.05.020. PMID: 21684292
Membrane lipid composition and cellular function.
Spector AA, Yorek MA
J Lipid Res 1985 Sep;26(9):1015-35. PMID: 3906008

Recent systematic reviews

What are the immune responses during the growth of Ehrlich's tumor in ascitic and solid form?
Feitosa IB, Mori B, Teles CBG, Costa AGD
Life Sci 2021 Jan 1;264:118578. Epub 2020 Oct 13 doi: 10.1016/j.lfs.2020.118578. PMID: 33058910

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...