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Papillary carcinoma

MedGen UID:
40105
•Concept ID:
C0007133
•
Neoplastic Process
Synonyms: Carcinoma, Papillary; Carcinomas, Papillary; Papillary Carcinoma; Papillary Carcinomas
SNOMED CT: Papillary carcinoma (25910003)
 
Monarch Initiative: MONDO:0006509

Definition

A malignant epithelial neoplasm characterized by a papillary growth pattern. A papillary carcinoma may be composed of glandular cells (papillary adenocarcinoma), squamous cells (papillary squamous cell carcinoma), or transitional cells (papillary transitional cell carcinoma). Bladder carcinoma is a representative example of papillary transitional cell carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPapillary carcinoma

Professional guidelines

PubMed

The Diagnosis and Treatment of Ampullary Carcinoma.
Walter D, Schnitzbauer AA, Schulze F, Trojan J
Dtsch Arztebl Int 2023 Oct 27;120(43):729-735. doi: 10.3238/arztebl.m2023.0195. PMID: 37656482Free PMC Article
Differential Diagnosis of Benign and Malignant Breast Papillary Neoplasms on MRI With Non-mass Enhancement.
Zhou J, Li M, Liu D, Sheng F, Cai J
Acad Radiol 2023 Sep;30 Suppl 2:S127-S132. Epub 2023 Mar 9 doi: 10.1016/j.acra.2023.02.010. PMID: 36906443
Thyroid Carcinoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
Haddad RI, Bischoff L, Ball D, Bernet V, Blomain E, Busaidy NL, Campbell M, Dickson P, Duh QY, Ehya H, Goldner WS, Guo T, Haymart M, Holt S, Hunt JP, Iagaru A, Kandeel F, Lamonica DM, Mandel S, Markovina S, McIver B, Raeburn CD, Rezaee R, Ridge JA, Roth MY, Scheri RP, Shah JP, Sipos JA, Sippel R, Sturgeon C, Wang TN, Wirth LJ, Wong RJ, Yeh M, Cassara CJ, Darlow S
J Natl Compr Canc Netw 2022 Aug;20(8):925-951. doi: 10.6004/jnccn.2022.0040. PMID: 35948029

Recent clinical studies

Etiology

Papillary lesions of the breast - review and practical issues.
Ni Y, Tse GM
Semin Diagn Pathol 2022 Sep;39(5):344-354. Epub 2022 Jun 11 doi: 10.1053/j.semdp.2022.06.001. PMID: 35718581
Papillary Neoplasms of the Breast: Diagnostic Features and Molecular Insights.
Ross DS, D'Alfonso TM
Surg Pathol Clin 2022 Mar;15(1):133-146. Epub 2022 Jan 31 doi: 10.1016/j.path.2021.11.009. PMID: 35236629
Molecular analysis of encapsulated papillary carcinoma of the breast with and without invasion.
Schwartz CJ, Boroujeni AM, Khodadadi-Jamayran A, Heguy A, Snuderl M, Jour G, Cotzia P, Darvishian F
Hum Pathol 2021 May;111:67-74. Epub 2021 Mar 3 doi: 10.1016/j.humpath.2021.02.005. PMID: 33667422
Neuroendocrine Tumors of the Breast.
Visscher DW, Yasir S
Endocr Pathol 2017 Jun;28(2):121-127. doi: 10.1007/s12022-017-9477-4. PMID: 28389994
Follicular carcinoma.
Franssila KO, Ackerman LV, Brown CL, Hedinger CE
Semin Diagn Pathol 1985 May;2(2):101-22. PMID: 3843689

Diagnosis

Differential Diagnosis of Benign and Malignant Breast Papillary Neoplasms on MRI With Non-mass Enhancement.
Zhou J, Li M, Liu D, Sheng F, Cai J
Acad Radiol 2023 Sep;30 Suppl 2:S127-S132. Epub 2023 Mar 9 doi: 10.1016/j.acra.2023.02.010. PMID: 36906443
Papillary lesions of the breast - review and practical issues.
Ni Y, Tse GM
Semin Diagn Pathol 2022 Sep;39(5):344-354. Epub 2022 Jun 11 doi: 10.1053/j.semdp.2022.06.001. PMID: 35718581
Papillary neoplasms of the breast-reviewing the spectrum.
Tay TKY, Tan PH
Mod Pathol 2021 Jun;34(6):1044-1061. Epub 2021 Jan 18 doi: 10.1038/s41379-020-00732-3. PMID: 33462367
Molecular genetics and diagnosis of thyroid cancer.
Nikiforov YE, Nikiforova MN
Nat Rev Endocrinol 2011 Aug 30;7(10):569-80. doi: 10.1038/nrendo.2011.142. PMID: 21878896
Papillary thyroid carcinoma variants.
Lloyd RV, Buehler D, Khanafshar E
Head Neck Pathol 2011 Mar;5(1):51-6. Epub 2011 Jan 8 doi: 10.1007/s12105-010-0236-9. PMID: 21221869Free PMC Article

Therapy

Checkpoint inhibitors in metastatic papillary renal cell carcinoma.
de Vries-Brilland M, McDermott DF, Suárez C, Powles T, Gross-Goupil M, Ravaud A, Flippot R, Escudier B, Albigès L
Cancer Treat Rev 2021 Sep;99:102228. Epub 2021 May 20 doi: 10.1016/j.ctrv.2021.102228. PMID: 34111642
Papillary thyroid microcarcinoma: optimal management versus overtreatment.
Walgama E, Sacks WL, Ho AS
Curr Opin Oncol 2020 Jan;32(1):1-6. doi: 10.1097/CCO.0000000000000595. PMID: 31633497
Effect of Intravesical Instillation of Gemcitabine vs Saline Immediately Following Resection of Suspected Low-Grade Non-Muscle-Invasive Bladder Cancer on Tumor Recurrence: SWOG S0337 Randomized Clinical Trial.
Messing EM, Tangen CM, Lerner SP, Sahasrabudhe DM, Koppie TM, Wood DP Jr, Mack PC, Svatek RS, Evans CP, Hafez KS, Culkin DJ, Brand TC, Karsh LI, Holzbeierlein JM, Wilson SS, Wu G, Plets M, Vogelzang NJ, Thompson IM Jr
JAMA 2018 May 8;319(18):1880-1888. doi: 10.1001/jama.2018.4657. PMID: 29801011Free PMC Article
Uterine papillary serous carcinoma.
Moore KN, Fader AN
Clin Obstet Gynecol 2011 Jun;54(2):278-91. doi: 10.1097/GRF.0b013e318218c755. PMID: 21508697
Thyroid carcinoma.
Weber T, Schilling T, Büchler MW
Curr Opin Oncol 2006 Jan;18(1):30-5. doi: 10.1097/01.cco.0000198975.36368.d3. PMID: 16357561

Prognosis

Extent of Surgery and the Prognosis of Unilateral Papillary Thyroid Microcarcinoma.
Zhao H, Cui L
Front Endocrinol (Lausanne) 2021;12:655608. Epub 2021 Jun 16 doi: 10.3389/fendo.2021.655608. PMID: 34220708Free PMC Article
Active Surveillance as First-Line Management of Papillary Microcarcinoma.
Ito Y, Miyauchi A
Annu Rev Med 2019 Jan 27;70:369-379. Epub 2018 Sep 19 doi: 10.1146/annurev-med-051517-125510. PMID: 30230964
Prognostic value of lymph node ratio in metastatic papillary thyroid carcinoma.
Mansour J, Sagiv D, Alon E, Talmi Y
J Laryngol Otol 2018 Jan;132(1):8-13. Epub 2017 Nov 10 doi: 10.1017/S0022215117002250. PMID: 29122022
Pediatric Thyroid Microcarcinoma.
Lerner J, Goldfarb M
Ann Surg Oncol 2015 Dec;22(13):4187-92. Epub 2015 Apr 9 doi: 10.1245/s10434-015-4546-8. PMID: 25854844
Pediatric thyroid cancer.
Chaukar DA, Rangarajan V, Nair N, Dcruz AK, Nadkarni MS, Pai PS, Mistry RC
J Surg Oncol 2005 Nov 1;92(2):130-3. doi: 10.1002/jso.20339. PMID: 16231375

Clinical prediction guides

Artificial Intelligence in Thyroid Fine Needle Aspiration Biopsies.
Kezlarian B, Lin O
Acta Cytol 2021;65(4):324-329. Epub 2020 Dec 16 doi: 10.1159/000512097. PMID: 33326953Free PMC Article
Thyroid Tumors You Don't Want to Miss.
Wong KS, Barletta JA
Surg Pathol Clin 2019 Dec;12(4):901-919. doi: 10.1016/j.path.2019.08.008. PMID: 31672297
Updates in Thyroid Cytology.
Nishino M, Krane JF
Surg Pathol Clin 2018 Sep;11(3):467-487. doi: 10.1016/j.path.2018.05.002. PMID: 30190135
Development and Validation of a Multi-institutional Preoperative Nomogram for Predicting Grade of Dysplasia in Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas: A Report from The Pancreatic Surgery Consortium.
Attiyeh MA, Fernández-Del Castillo C, Al Efishat M, Eaton AA, Gönen M, Batts R, Pergolini I, Rezaee N, Lillemoe KD, Ferrone CR, Mino-Kenudson M, Weiss MJ, Cameron JL, Hruban RH, D'Angelica MI, DeMatteo RP, Kingham TP, Jarnagin WR, Wolfgang CL, Allen PJ
Ann Surg 2018 Jan;267(1):157-163. doi: 10.1097/SLA.0000000000002015. PMID: 28079542Free PMC Article
Variants of Papillary Thyroid Carcinoma: Multiple Faces of a Familiar Tumor.
Sak SD
Turk Patoloji Derg 2015;31 Suppl 1:34-47. doi: 10.5146/tjpath.2015.01313. PMID: 26177316

Recent systematic reviews

Global incidence and prevalence of differentiated thyroid cancer in childhood: systematic review and meta-analysis.
Moleti M, Aversa T, Crisafulli S, Trifirò G, Corica D, Pepe G, Cannavò L, Di Mauro M, Paola G, Fontana A, Calapai F, Cannavò S, Wasniewska M
Front Endocrinol (Lausanne) 2023;14:1270518. Epub 2023 Sep 19 doi: 10.3389/fendo.2023.1270518. PMID: 37795368Free PMC Article
Risk and Prognostic Factors for BRAF(V600E) Mutations in Papillary Thyroid Carcinoma.
Wei X, Wang X, Xiong J, Li C, Liao Y, Zhu Y, Mao J
Biomed Res Int 2022;2022:9959649. Epub 2022 May 18 doi: 10.1155/2022/9959649. PMID: 35647194Free PMC Article
Assessment of Radiofrequency Ablation for Papillary Microcarcinoma of the Thyroid: A Systematic Review and Meta-analysis.
van Dijk SPJ, Coerts HI, Gunput STG, van Velsen EFS, Medici M, Moelker A, Peeters RP, Verhoef C, van Ginhoven TM
JAMA Otolaryngol Head Neck Surg 2022 Apr 1;148(4):317-325. doi: 10.1001/jamaoto.2021.4381. PMID: 35142816Free PMC Article
Hobnail variant of papillary thyroid carcinoma: a systematic review and meta-analysis.
Donaldson LB, Yan F, Morgan PF, Kaczmar JM, Fernandes JK, Nguyen SA, Jester RL, Day TA
Endocrine 2021 Apr;72(1):27-39. Epub 2020 Oct 6 doi: 10.1007/s12020-020-02505-z. PMID: 33025563Free PMC Article
Differentiated Thyroid Cancer-Treatment: State of the Art.
Schmidbauer B, Menhart K, Hellwig D, Grosse J
Int J Mol Sci 2017 Jun 17;18(6) doi: 10.3390/ijms18061292. PMID: 28629126Free PMC Article

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