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Catastrophic Illness

MedGen UID:
40139
•Concept ID:
C0007397
•
Disease or Syndrome
Synonyms: Catastrophic Illnesses; Illness, Catastrophic; Illnesses, Catastrophic

Definition

An acute or prolonged illness usually considered to be life-threatening or with the threat of serious residual disability. Treatment may be radical and is frequently costly. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCatastrophic Illness

Professional guidelines

PubMed

Gonadotropin-releasing hormone agonist treatment and ischemic heart disease among female patients with breast cancer: A cohort study.
Chou YS, Wang CC, Hsu LF, Chuang PH, Cheng CF, Li NH, Chen CC, Chen CL, Lai YJ, Yen YF
Cancer Med 2023 Mar;12(5):5536-5544. Epub 2022 Oct 28 doi: 10.1002/cam4.5390. PMID: 36305849Free PMC Article
Primary Sjogren's syndrome and the risk of acute pancreatitis: a nationwide cohort study.
Chang CC, Chang YS, Wang SH, Lin SY, Chen YH, Chen JH
BMJ Open 2017 Aug 11;7(8):e014807. doi: 10.1136/bmjopen-2016-014807. PMID: 28801391Free PMC Article
End-of-life decision making by adolescents, parents, and healthcare providers in pediatric oncology: research to evidence-based practice guidelines.
Hinds PS, Oakes L, Furman W, Quargnenti A, Olson MS, Foppiano P, Srivastava DK
Cancer Nurs 2001 Apr;24(2):122-34; quiz 135-6. doi: 10.1097/00002820-200104000-00007. PMID: 11318260

Recent clinical studies

Etiology

Eculizumab use in catastrophic antiphospholipid syndrome (CAPS): Descriptive analysis from the "CAPS Registry".
López-Benjume B, Rodríguez-Pintó I, Amigo MC, Erkan D, Shoenfeld Y, Cervera R, Espinosa G; on behalf the CAPS Registry Project Group/European Forum on Antiphospholipid Antibodies
Autoimmun Rev 2022 Apr;21(4):103055. Epub 2022 Jan 24 doi: 10.1016/j.autrev.2022.103055. PMID: 35085802
Physical multimorbidity, health service use, and catastrophic health expenditure by socioeconomic groups in China: an analysis of population-based panel data.
Zhao Y, Atun R, Oldenburg B, McPake B, Tang S, Mercer SW, Cowling TE, Sum G, Qin VM, Lee JT
Lancet Glob Health 2020 Jun;8(6):e840-e849. doi: 10.1016/S2214-109X(20)30127-3. PMID: 32446349Free PMC Article
Preventing and managing catastrophic bleeding during extracorporeal circulation.
Karkouti K, Ho LTS
Hematology Am Soc Hematol Educ Program 2018 Nov 30;2018(1):522-529. doi: 10.1182/asheducation-2018.1.522. PMID: 30504353Free PMC Article
How to avoid catastrophic events on the ward.
Bein B, Seewald S, Gräsner JT
Best Pract Res Clin Anaesthesiol 2016 Jun;30(2):237-45. Epub 2016 May 3 doi: 10.1016/j.bpa.2016.04.003. PMID: 27396810
Treatment of catastrophic antiphospholipid syndrome.
Kazzaz NM, McCune WJ, Knight JS
Curr Opin Rheumatol 2016 May;28(3):218-27. doi: 10.1097/BOR.0000000000000269. PMID: 26927441Free PMC Article

Diagnosis

The rheumatology/hematology interface: CAPS and MAS diagnosis and management.
Gansner JM, Berliner N
Hematology Am Soc Hematol Educ Program 2018 Nov 30;2018(1):313-317. doi: 10.1182/asheducation-2018.1.313. PMID: 30504326Free PMC Article
The diagnosis and clinical management of the catastrophic antiphospholipid syndrome: A comprehensive review.
Cervera R, Rodríguez-Pintó I, Espinosa G
J Autoimmun 2018 Aug;92:1-11. Epub 2018 May 18 doi: 10.1016/j.jaut.2018.05.007. PMID: 29779928
Treatment of catastrophic antiphospholipid syndrome.
Kazzaz NM, McCune WJ, Knight JS
Curr Opin Rheumatol 2016 May;28(3):218-27. doi: 10.1097/BOR.0000000000000269. PMID: 26927441Free PMC Article
Catastrophic antiphospholipid syndrome.
Vora SK, Asherson RA, Erkan D
J Intensive Care Med 2006 May-Jun;21(3):144-59. doi: 10.1177/0885066606287041. PMID: 16672637
Cerebrospinal fluid.
Jerrard DA, Hanna JR, Schindelheim GL
J Emerg Med 2001 Aug;21(2):171-8. doi: 10.1016/s0736-4679(01)00360-2. PMID: 11489408

Therapy

Preventing and managing catastrophic bleeding during extracorporeal circulation.
Karkouti K, Ho LTS
Hematology Am Soc Hematol Educ Program 2018 Nov 30;2018(1):522-529. doi: 10.1182/asheducation-2018.1.522. PMID: 30504353Free PMC Article
The diagnosis and clinical management of the catastrophic antiphospholipid syndrome: A comprehensive review.
Cervera R, Rodríguez-Pintó I, Espinosa G
J Autoimmun 2018 Aug;92:1-11. Epub 2018 May 18 doi: 10.1016/j.jaut.2018.05.007. PMID: 29779928
Treatment of catastrophic antiphospholipid syndrome.
Kazzaz NM, McCune WJ, Knight JS
Curr Opin Rheumatol 2016 May;28(3):218-27. doi: 10.1097/BOR.0000000000000269. PMID: 26927441Free PMC Article
Acute liver failure.
Pathikonda M, Munoz SJ
Ann Hepatol 2010 Jan-Mar;9(1):7-14. PMID: 20308717
Catastrophic antiphospholipid syndrome.
Cervera R, Asherson RA, Font J
Rheum Dis Clin North Am 2006 Aug;32(3):575-90. doi: 10.1016/j.rdc.2006.05.002. PMID: 16880085

Prognosis

Preventing and managing catastrophic bleeding during extracorporeal circulation.
Karkouti K, Ho LTS
Hematology Am Soc Hematol Educ Program 2018 Nov 30;2018(1):522-529. doi: 10.1182/asheducation-2018.1.522. PMID: 30504353Free PMC Article
CAPS Registry.
Cervera R
Lupus 2012 Jun;21(7):755-7. doi: 10.1177/0961203312436866. PMID: 22635223
Acute liver failure.
Pathikonda M, Munoz SJ
Ann Hepatol 2010 Jan-Mar;9(1):7-14. PMID: 20308717
Catastrophic antiphospholipid syndrome.
Vora SK, Asherson RA, Erkan D
J Intensive Care Med 2006 May-Jun;21(3):144-59. doi: 10.1177/0885066606287041. PMID: 16672637
Catastrophic antiphospholipid syndrome.
Asherson RA, Cervera R
Curr Rheumatol Rep 2003 Oct;5(5):395-400. doi: 10.1007/s11926-003-0031-7. PMID: 12967527

Clinical prediction guides

Defining catastrophic brain injury in children leading to coma and disorders of consciousness and the scope of the problem.
LaRovere KL, Tasker RC
Curr Opin Pediatr 2020 Dec;32(6):750-758. doi: 10.1097/MOP.0000000000000951. PMID: 33009124
Preventing and managing catastrophic bleeding during extracorporeal circulation.
Karkouti K, Ho LTS
Hematology Am Soc Hematol Educ Program 2018 Nov 30;2018(1):522-529. doi: 10.1182/asheducation-2018.1.522. PMID: 30504353Free PMC Article
Catastrophic antiphospholipid syndrome: an update.
Espinosa G, Rodríguez-Pintó I, Cervera R
Panminerva Med 2017 Sep;59(3):254-268. Epub 2017 May 8 doi: 10.23736/S0031-0808.17.03324-9. PMID: 28488841
How to avoid catastrophic events on the ward.
Bein B, Seewald S, Gräsner JT
Best Pract Res Clin Anaesthesiol 2016 Jun;30(2):237-45. Epub 2016 May 3 doi: 10.1016/j.bpa.2016.04.003. PMID: 27396810
Catastrophic pediatric sports injuries.
Luckstead EF, Patel DR
Pediatr Clin North Am 2002 Jun;49(3):581-91. doi: 10.1016/s0031-3955(02)00006-8. PMID: 12119866

Recent systematic reviews

Palliative and end-of-life care needs, experiences, and preferences of LGBTQ+ individuals with serious illness: A systematic mixed-methods review.
Rosa WE, Roberts KE, Braybrook D, Harding R, Godwin K, Mahoney C, Mathew S, Atkinson TM, Banerjee SC, Haviland K, Hughes TL, Walters CB, Parker PA
Palliat Med 2023 Apr;37(4):460-474. Epub 2022 Dec 7 doi: 10.1177/02692163221124426. PMID: 36475950Free PMC Article
Catastrophic health expenditure in sub-Saharan Africa: systematic review and meta-analysis.
Eze P, Lawani LO, Agu UJ, Acharya Y
Bull World Health Organ 2022 May 1;100(5):337-351J. Epub 2022 Apr 4 doi: 10.2471/BLT.21.287673. PMID: 35521041Free PMC Article
Financial Protection Indexes and the Iranian Health Transformation Plan: A Systematic Review.
Darvishi B, Behzadifar M, Ghanbari MK, Ehsanzadeh SJ, Bakhtiari A, Behzadifar M, Azari S, Bragazzi NL
Yale J Biol Med 2021 Sep;94(3):465-476. Epub 2021 Sep 30 PMID: 34602884Free PMC Article
Tools to Promote Shared Decision Making in Serious Illness: A Systematic Review.
Austin CA, Mohottige D, Sudore RL, Smith AK, Hanson LC
JAMA Intern Med 2015 Jul;175(7):1213-21. doi: 10.1001/jamainternmed.2015.1679. PMID: 25985438Free PMC Article
Thromboprophylaxis and obstetric management of the antiphospholipid syndrome.
Espinosa G, Cervera R
Expert Opin Pharmacother 2009 Mar;10(4):601-14. doi: 10.1517/14656560902772302. PMID: 19284363

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