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Papillomatosis, florid, of nipple

MedGen UID:
401492
•Concept ID:
C1868647
•
Neoplastic Process
Synonyms: Erosive adenomatosis of the nipple; Florid papillomatosis; Florid papillomatosis of the nipple
 
Monarch Initiative: MONDO:0008189
OMIM®: 167950

Definition

A rare benign neoplasm that arises in the area of the nipple. Clinically, it usually presents as a tender erythematous crusting lesion with hardening of the nipple. Morphologically, there is proliferation of ducts lined with epithelial and myoepithelial cells and focal erosion of the epidermis. [from MONDO]

Clinical features

From HPO
Abnormality of the skin
MedGen UID:
1845238
•Concept ID:
C5848159
•
Anatomical Abnormality
An abnormality of the skin.
See: Feature record | Search on this feature

Professional guidelines

PubMed

Erosive adenomatosis of the nipple: histology, immunohistology, and differential diagnosis.
Diaz NM, Palmer JO, Wick MR
Mod Pathol 1992 Mar;5(2):179-84. PMID: 1574495

Recent clinical studies

Etiology

Management of nipple adenomas during pregnancy: a case report.
Combi F, Palma E, Montorsi G, Gambini A, Segattini S, Papi S, Andreotti A, Tazzioli G
Int Breastfeed J 2023 Mar 21;18(1):19. doi: 10.1186/s13006-023-00554-4. PMID: 36945004Free PMC Article
Florid papillomatosis of the nipple.
Dinesh BJ, Hayati F, Azizan N, Abdul Rashid NF
BMJ Case Rep 2019 Sep 18;12(9) doi: 10.1136/bcr-2019-231516. PMID: 31537599Free PMC Article
Erosive adenomatosis of the nipple in an eight-year-old girl.
Albers SE, Barnard M, Thorner P, Krafchik BR
J Am Acad Dermatol 1999 May;40(5 Pt 2):834-7. doi: 10.1053/jd.1999.v40.a95510. PMID: 10321629

Diagnosis

Nipple Ultrasound: A Pictorial Essay.
Chiorean A, Pintican RM, Szep M, Feier D, Rogojan L, Fetica B, Dindelegan G, Vlad B, Duma M
Korean J Radiol 2020 Aug;21(8):955-966. doi: 10.3348/kjr.2019.0831. PMID: 32677380Free PMC Article
Erythematous eroded plaque on the left nipple in a 75-year-old woman.
Alvarez-Veliz S, Majluf-Caceres P, González-Bombardiére S
Indian J Dermatol Venereol Leprol 2019 May-Jun;85(3):307-309. doi: 10.4103/ijdvl.IJDVL_446_17. PMID: 30058561
Mammary and extramammary Paget's disease.
Lopes Filho LL, Lopes IM, Lopes LR, Enokihara MM, Michalany AO, Matsunaga N
An Bras Dermatol 2015 Mar-Apr;90(2):225-31. doi: 10.1590/abd1806-4841.20153189. PMID: 25830993Free PMC Article
Erosive adenomatosis of the nipple.
Cosechen MS, Wojcik AS, Piva FM, Werner B, Serafini SZ
An Bras Dermatol 2011 Jul-Aug;86(4 Suppl 1):S17-20. doi: 10.1590/s0365-05962011000700003. PMID: 22068761
Erosive adenomatosis of the nipple.
Smith EJ, Kron SD, Gross PR
Arch Dermatol 1970 Sep;102(3):330-2. PMID: 4318454

Therapy

5-Aminolevulinic acid induced photodynamic therapy (ALA-PDT) for erosive adenomatosis of the nipple: A case report.
Zhou X, Zheng M, Zou Y, Wang J, Zhang L, Yin R
Photodiagnosis Photodyn Ther 2021 Sep;35:102387. Epub 2021 Jun 7 doi: 10.1016/j.pdpdt.2021.102387. PMID: 34107318
Recurrent syringomatous adenoma of the nipple following a misdiagnosis: A case report.
Abeciunas V, Jurgaitis K, Jakutis N
Niger J Clin Pract 2020 Sep;23(9):1324-1327. doi: 10.4103/njcp.njcp_1_20. PMID: 32913175

Prognosis

Mammary and extramammary Paget's disease.
Lopes Filho LL, Lopes IM, Lopes LR, Enokihara MM, Michalany AO, Matsunaga N
An Bras Dermatol 2015 Mar-Apr;90(2):225-31. doi: 10.1590/abd1806-4841.20153189. PMID: 25830993Free PMC Article
Erosive adenomatosis of the nipple.
Cosechen MS, Wojcik AS, Piva FM, Werner B, Serafini SZ
An Bras Dermatol 2011 Jul-Aug;86(4 Suppl 1):S17-20. doi: 10.1590/s0365-05962011000700003. PMID: 22068761

Clinical prediction guides

Erosive adenomatosis of the nipple.
Bourlond J, Bourlond-Reinert L
Dermatology 1992;185(4):319-24. doi: 10.1159/000247483. PMID: 1477435

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