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Poroma

MedGen UID:
404005
Concept ID:
C2717981
Neoplastic Process
Synonyms: Poromas; Poromatoses; Poromatosis
 
HPO: HP:0031405

Definition

A benign, well circumscribed sweat gland neoplasm with eccrine or apocrine differentiation. It usually presents as a solitary, dome-shaped papule, nodule, or plaque on acral sites. It is characterized by a proliferation of uniform basaloid cells in the dermis and it is associated with the presence of focal ductal and cystic structures [NCIT:C27273]. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPoroma

Conditions with this feature

SchC6pf-Schulz-Passarge syndrome
MedGen UID:
347366
Concept ID:
C1857069
Disease or Syndrome
Schopf-Schulz-Passarge syndrome (SSPS) is an autosomal recessive disorder characterized by a constellation of multiple eyelid cysts, hypodontia, hypotrichosis, palmoplantar hyperkeratosis, and onychodystrophy (summary by Mallaiah and Dickinson, 2001).

Professional guidelines

PubMed

Schukow C, McCalmont TH, Surprenant D, Yang HH
Am J Dermatopathol 2023 Oct 1;45(10):728-730. Epub 2023 Jul 28 doi: 10.1097/DAD.0000000000002503. PMID: 37506277
Takayama R, Ansai S, Ishiwata T, Yamamoto T, Matsuda Y, Naito Z, Kawana S
Am J Dermatopathol 2014 Aug;36(8):655-60. doi: 10.1097/DAD.0b013e31828b6bbf. PMID: 23656908
Aslan F, Demirkesen C, Cağatay P, Tüzüner N
J Cutan Pathol 2006 Aug;33(8):531-8. doi: 10.1111/j.1600-0560.2006.00466.x. PMID: 16919026

Recent clinical studies

Etiology

Kneiber D, Cassarino DS
Am J Dermatopathol 2022 May 1;44(5):e51-e53. doi: 10.1097/DAD.0000000000002123. PMID: 35120031
Kawaguchi M, Kato H, Imada H, Miyazaki T, Matsuyama K, Seishima M, Matsuo M
J Comput Assist Tomogr 2021 May-Jun 01;45(3):447-451. doi: 10.1097/RCT.0000000000001146. PMID: 33797441
Ha DL, Lee GW, Shin K, Kim HS, Ko HC, Kim BS, Kim MB
J Cutan Med Surg 2021 Mar-Apr;25(2):142-149. Epub 2020 Sep 3 doi: 10.1177/1203475420952432. PMID: 32880198
Ogawa T, Donizy P, Wu CL, Cornejo KM, Ryś J, Hoang MP
Am J Dermatopathol 2020 Sep;42(9):629-640. doi: 10.1097/DAD.0000000000001548. PMID: 32833736
Sawaya JL, Khachemoune A
Int J Dermatol 2014 Sep;53(9):1053-61. Epub 2014 Apr 2 doi: 10.1111/ijd.12448. PMID: 24697501

Diagnosis

Kervarrec T, Frouin E, Collin C, Tallet A, Tallegas M, Pissaloux D, Tirode F, Guyétant S, Samimi M, Gaboriaud P, Touzé A, Schrama D, Houben R, Tabareau-Delalande F, Neuhart A, de la Fouchardière A, Osio A, Cavelier-Balloy B, Laurent-Roussel S, Sohier P, Cyprien T, Balme B, Belzung F, Jullie ML, Cribier B, Battistella M, Macagno N
Histopathology 2023 May;82(6):885-898. Epub 2023 Feb 22 doi: 10.1111/his.14874. PMID: 36720791
Rao EM, Knackstedt TJ
Int J Dermatol 2022 Jul;61(7):812-820. Epub 2021 Sep 8 doi: 10.1111/ijd.15893. PMID: 34494261
Kumar P, Das A, Das PC
Indian J Dermatol Venereol Leprol 2020 Nov-Dec;86(6):681-682. doi: 10.4103/ijdvl.IJDVL_924_18. PMID: 31249214
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149
McCalmont TH
J Cutan Pathol 2014 Feb;41(2):78-80. doi: 10.1111/cup.12291. PMID: 24460880

Therapy

Nguyen K, Kim G, Chiu M
Dermatol Online J 2019 Nov 15;25(11) PMID: 32045152
Fujii K, Aochi S, Takeshima C, Ohtsuka M, Hamada T, Asagoe K, Aoyama Y, Morizane S, Iwatsuki K
Acta Derm Venereol 2012 Nov;92(6):687-90. doi: 10.2340/00015555-1279. PMID: 22294042
Maraga S, Plüss B, Schöpflin S, Sie A, Iga J, Ousari M, Yala S, Meier G, Reeder JC, Mueller I
P N G Med J 2011 Mar-Jun;54(1-2):35-47. PMID: 23763037
Brown CW Jr, Dy LC
Dermatol Ther 2008 Nov-Dec;21(6):433-8. doi: 10.1111/j.1529-8019.2008.00243.x. PMID: 19076620
Langbein L, Cribier B, Schirmacher P, Praetzel-Wunder S, Peltre B, Schweizer J
Br J Dermatol 2008 Sep;159(3):633-45. Epub 2008 Jul 19 doi: 10.1111/j.1365-2133.2008.08746.x. PMID: 18647305

Prognosis

Kervarrec T, Pissaloux D, Tirode F, de la Fouchardière A, Sohier P, Frouin E, Hamard A, Houben R, Schrama D, Barlier A, Cribier B, Battistella M, Macagno N
Histopathology 2024 Jan;84(2):266-278. Epub 2023 Aug 23 doi: 10.1111/his.15023. PMID: 37609771
Koblinski JE, Ahrns HT, Morse MJ, Seiverling EV
J Am Podiatr Med Assoc 2022 Mar 16;112(1) doi: 10.7547/20-184. PMID: 36459055
Ogawa T, Donizy P, Wu CL, Cornejo KM, Ryś J, Hoang MP
Am J Dermatopathol 2020 Sep;42(9):629-640. doi: 10.1097/DAD.0000000000001548. PMID: 32833736
Le NS, Janik S, Liu DT, Grasl S, Faisal M, Pammer J, Schickinger-Fischer B, Hamzavi JS, Seemann R, Erovic BM
Head Neck 2020 Sep;42(9):2644-2659. Epub 2020 Apr 21 doi: 10.1002/hed.26178. PMID: 32314845
Karadag AS, Parish LC, Lambert WC
Skinmed 2017;15(2):91-92. Epub 2017 Apr 1 PMID: 28528600

Clinical prediction guides

Kervarrec T, Frouin E, Collin C, Tallet A, Tallegas M, Pissaloux D, Tirode F, Guyétant S, Samimi M, Gaboriaud P, Touzé A, Schrama D, Houben R, Tabareau-Delalande F, Neuhart A, de la Fouchardière A, Osio A, Cavelier-Balloy B, Laurent-Roussel S, Sohier P, Cyprien T, Balme B, Belzung F, Jullie ML, Cribier B, Battistella M, Macagno N
Histopathology 2023 May;82(6):885-898. Epub 2023 Feb 22 doi: 10.1111/his.14874. PMID: 36720791
Plotzke JM, Adams DJ, Harms PW
Histopathology 2022 Jan;80(1):166-183. doi: 10.1111/his.14441. PMID: 34197659
Ha DL, Lee GW, Shin K, Kim HS, Ko HC, Kim BS, Kim MB
J Cutan Med Surg 2021 Mar-Apr;25(2):142-149. Epub 2020 Sep 3 doi: 10.1177/1203475420952432. PMID: 32880198
Ogawa T, Donizy P, Wu CL, Cornejo KM, Ryś J, Hoang MP
Am J Dermatopathol 2020 Sep;42(9):629-640. doi: 10.1097/DAD.0000000000001548. PMID: 32833736
Zaballos P, Gómez-Martín I, Martin JM, Bañuls J
Dermatol Clin 2018 Oct;36(4):397-412. Epub 2018 Aug 16 doi: 10.1016/j.det.2018.05.007. PMID: 30201149

Recent systematic reviews

Rao EM, Knackstedt TJ
Int J Dermatol 2022 Jul;61(7):812-820. Epub 2021 Sep 8 doi: 10.1111/ijd.15893. PMID: 34494261

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