U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Acrospiromas

MedGen UID:
404704
•Concept ID:
C2718092
•
Neoplastic Process
Synonyms: Acrospiroma; Hidradenoma; Hidradenomas; Spiradenoma; Spiradenomas

Definition

A rare cutaneous tumor of apocrine or eccrine SWEAT GLAND origin. It is most commonly found on the extremities and is usually benign. It appears as a solitary nodule or cyst and may be solid or produce a watery discharge. It is related to POROMA except in acrospiroma it does not involve the epidermis. There is no indication that heredity or external agents cause these tumors. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcrospiromas

Recent clinical studies

Etiology

Mitotic figures in sweat gland adenomas.
Cooper PH
J Cutan Pathol 1987 Feb;14(1):10-4. doi: 10.1111/j.1600-0560.1987.tb00121.x. PMID: 3558913
The significance of atypical nuclear changes in benign eccrine acrospiromas: a clinical and pathological study of 18 cases.
Mambo NC
J Cutan Pathol 1984 Feb;11(1):35-44. doi: 10.1111/j.1600-0560.1984.tb00347.x. PMID: 6321571
Sweat gland carcinomas in children.
Chow CW, Campbell PE, Burry AF
Cancer 1984 Mar 1;53(5):1222-7. doi: 10.1002/1097-0142(19840301)53:5<1222::aid-cncr2820530533>3.0.co;2-a. PMID: 6318962

Diagnosis

Cytokeratin 5/6 immunostaining in cutaneous adnexal neoplasms and metastatic adenocarcinoma.
Plumb SJ, Argenyi ZB, Stone MS, De Young BR
Am J Dermatopathol 2004 Dec;26(6):447-51. doi: 10.1097/00000372-200412000-00001. PMID: 15618924
Malignant eccrine acrospiroma with metastasis to the parotid.
Holden B, Colome-Grimmer M, Savage C, Stierman K, Pou AM
Ear Nose Throat J 2002 May;81(5):352-5. PMID: 12025008
Assessment of cellular proliferation of eccrine acrospiromas and eccrine sweat gland carcinomas by AgNOR counting and immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) and Ki-67.
Ansai S, Koseki S, Hozumi Y, Kondo S
Clin Exp Dermatol 1995 Jan;20(1):27-34. doi: 10.1111/j.1365-2230.1995.tb01278.x. PMID: 7671392
Microcystic adnexal carcinoma. An immunohistochemical comparison with other cutaneous appendage tumors.
Wick MR, Cooper PH, Swanson PE, Kaye VN, Sun TT
Arch Dermatol 1990 Feb;126(2):189-94. doi: 10.1001/archderm.126.2.189. PMID: 1689137

Prognosis

Assessment of cellular proliferation of eccrine acrospiromas and eccrine sweat gland carcinomas by AgNOR counting and immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) and Ki-67.
Ansai S, Koseki S, Hozumi Y, Kondo S
Clin Exp Dermatol 1995 Jan;20(1):27-34. doi: 10.1111/j.1365-2230.1995.tb01278.x. PMID: 7671392
The significance of atypical nuclear changes in benign eccrine acrospiromas: a clinical and pathological study of 18 cases.
Mambo NC
J Cutan Pathol 1984 Feb;11(1):35-44. doi: 10.1111/j.1600-0560.1984.tb00347.x. PMID: 6321571

Clinical prediction guides

Assessment of cellular proliferation of eccrine acrospiromas and eccrine sweat gland carcinomas by AgNOR counting and immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) and Ki-67.
Ansai S, Koseki S, Hozumi Y, Kondo S
Clin Exp Dermatol 1995 Jan;20(1):27-34. doi: 10.1111/j.1365-2230.1995.tb01278.x. PMID: 7671392
Mitotic figures in sweat gland adenomas.
Cooper PH
J Cutan Pathol 1987 Feb;14(1):10-4. doi: 10.1111/j.1600-0560.1987.tb00121.x. PMID: 3558913

Supplemental Content

Table of contents

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...