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Laryngeal Hemorrhage, CTCAE

MedGen UID:
406760
•Concept ID:
C1881362
•
Finding

Definition

A disorder characterized by bleeding from the larynx. [from NCI]

Recent clinical studies

Etiology

Predicting acute severe toxicity for head and neck squamous cell carcinomas by combining dosimetry with a radiosensitivity biomarker: a pilot study.
Deneuve S, Bastogne T, Duclos M, Mirjolet C, Bois P, Bachmann P, Nokovitch L, Roux PE, Girodet D, Poupart M, Zrounba P, Claude L, Ferella L, Iacovelli NA, Foray N, Rancati T, Pereira S
Tumori 2023 Apr;109(2):173-185. Epub 2022 May 16 doi: 10.1177/03008916221078061. PMID: 35578746
Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma.
Wise-Draper TM, Gulati S, Palackdharry S, Hinrichs BH, Worden FP, Old MO, Dunlap NE, Kaczmar JM, Patil Y, Riaz MK, Tang A, Mark J, Zender C, Gillenwater AM, Bell D, Kurtzweil N, Mathews M, Allen CL, Mierzwa ML, Casper K, Jandarov R, Medvedovic M, Lee JJ, Harun N, Takiar V, Gillison M
Clin Cancer Res 2022 Apr 1;28(7):1345-1352. doi: 10.1158/1078-0432.CCR-21-3351. PMID: 35338369Free PMC Article
Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy.
Margalit DN, Schoenfeld JD, Rawal B, Haddad RI, Catalano PJ, Goguen LA, Chau NG, Rabinowits G, Lorch JH, Annino DJ, Tishler RB
Oral Oncol 2017 Oct;73:160-165. Epub 2017 Sep 8 doi: 10.1016/j.oraloncology.2017.08.012. PMID: 28939070
Whole-Field Sequential Intensity-Modulated Radiotherapy for Local-Regional Advanced Head-and-Neck Squamous Cell Carcinoma.
Refaat T, Choi M, Thomas TO, Bacchus I, Agulnik M, Pelzer HJ, Mellott AL, Rademaker AW, Liu D, Sathiaseelan V, Mittal BB
Am J Clin Oncol 2015 Dec;38(6):588-94. doi: 10.1097/COC.0000000000000001. PMID: 24136140Free PMC Article

Therapy

Phase II Clinical Trial of Neoadjuvant and Adjuvant Pembrolizumab in Resectable Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma.
Wise-Draper TM, Gulati S, Palackdharry S, Hinrichs BH, Worden FP, Old MO, Dunlap NE, Kaczmar JM, Patil Y, Riaz MK, Tang A, Mark J, Zender C, Gillenwater AM, Bell D, Kurtzweil N, Mathews M, Allen CL, Mierzwa ML, Casper K, Jandarov R, Medvedovic M, Lee JJ, Harun N, Takiar V, Gillison M
Clin Cancer Res 2022 Apr 1;28(7):1345-1352. doi: 10.1158/1078-0432.CCR-21-3351. PMID: 35338369Free PMC Article
Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy.
Margalit DN, Schoenfeld JD, Rawal B, Haddad RI, Catalano PJ, Goguen LA, Chau NG, Rabinowits G, Lorch JH, Annino DJ, Tishler RB
Oral Oncol 2017 Oct;73:160-165. Epub 2017 Sep 8 doi: 10.1016/j.oraloncology.2017.08.012. PMID: 28939070
Whole-Field Sequential Intensity-Modulated Radiotherapy for Local-Regional Advanced Head-and-Neck Squamous Cell Carcinoma.
Refaat T, Choi M, Thomas TO, Bacchus I, Agulnik M, Pelzer HJ, Mellott AL, Rademaker AW, Liu D, Sathiaseelan V, Mittal BB
Am J Clin Oncol 2015 Dec;38(6):588-94. doi: 10.1097/COC.0000000000000001. PMID: 24136140Free PMC Article

Prognosis

Predicting acute severe toxicity for head and neck squamous cell carcinomas by combining dosimetry with a radiosensitivity biomarker: a pilot study.
Deneuve S, Bastogne T, Duclos M, Mirjolet C, Bois P, Bachmann P, Nokovitch L, Roux PE, Girodet D, Poupart M, Zrounba P, Claude L, Ferella L, Iacovelli NA, Foray N, Rancati T, Pereira S
Tumori 2023 Apr;109(2):173-185. Epub 2022 May 16 doi: 10.1177/03008916221078061. PMID: 35578746
Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy.
Margalit DN, Schoenfeld JD, Rawal B, Haddad RI, Catalano PJ, Goguen LA, Chau NG, Rabinowits G, Lorch JH, Annino DJ, Tishler RB
Oral Oncol 2017 Oct;73:160-165. Epub 2017 Sep 8 doi: 10.1016/j.oraloncology.2017.08.012. PMID: 28939070

Clinical prediction guides

Predicting acute severe toxicity for head and neck squamous cell carcinomas by combining dosimetry with a radiosensitivity biomarker: a pilot study.
Deneuve S, Bastogne T, Duclos M, Mirjolet C, Bois P, Bachmann P, Nokovitch L, Roux PE, Girodet D, Poupart M, Zrounba P, Claude L, Ferella L, Iacovelli NA, Foray N, Rancati T, Pereira S
Tumori 2023 Apr;109(2):173-185. Epub 2022 May 16 doi: 10.1177/03008916221078061. PMID: 35578746
Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy.
Margalit DN, Schoenfeld JD, Rawal B, Haddad RI, Catalano PJ, Goguen LA, Chau NG, Rabinowits G, Lorch JH, Annino DJ, Tishler RB
Oral Oncol 2017 Oct;73:160-165. Epub 2017 Sep 8 doi: 10.1016/j.oraloncology.2017.08.012. PMID: 28939070

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