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Venous thoracic outlet syndrome

MedGen UID:
408326
Concept ID:
C1956396
Disease or Syndrome
Synonym: Venous Thoracic Outlet Syndrome
SNOMED CT: Venous thoracic outlet syndrome (25981000119102); Paget Schrotter disease (25981000119102); Venous cervical rib syndrome (25981000119102); Effort subclavian vein thrombosis (25981000119102)
 
Monarch Initiative: MONDO:0018165
Orphanet: ORPHA357131

Definition

A form of thoracic outlet syndrome that manifests as unilateral (rarely bilateral) arm pain and cyanosis. The disease occurs in young adults, usually after excessive arm activity. The characteristic symptoms, caused by venous obstruction, are arm swelling, cyanosis and pain. Repetitive arm motion and compression of the subclavian vein in the neck (between the clavicle and the first rib) leads to scar tissue that can predispose to thrombosis due to narrowing of vessels. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVenous thoracic outlet syndrome

Professional guidelines

PubMed

Cook JR, Thompson RW
Thorac Surg Clin 2021 Feb;31(1):27-44. doi: 10.1016/j.thorsurg.2020.08.012. PMID: 33220769
Expert Panels on Vascular Imaging, Thoracic Imaging, and Neurological Imaging, Zurkiya O, Ganguli S, Kalva SP, Chung JH, Shah LM, Majdalany BS, Bykowski J, Carter BW, Chandra A, Collins JD, Gunn AJ, Kendi AT, Khaja MS, Liebeskind DS, Maldonado F, Obara P, Sutphin PD, Tong BC, Vijay K, Corey AS, Kanne JP, Dill KE
J Am Coll Radiol 2020 May;17(5S):S323-S334. doi: 10.1016/j.jacr.2020.01.029. PMID: 32370976
Cai TY, Rajendran S, Saha P, Dubenec S
Phlebology 2020 Aug;35(7):461-471. Epub 2020 Feb 6 doi: 10.1177/0268355519898920. PMID: 32028850

Recent clinical studies

Etiology

Illig KA, Gober L
J Vasc Surg Venous Lymphat Disord 2022 Mar;10(2):514-526. Epub 2021 Aug 2 doi: 10.1016/j.jvsv.2021.07.011. PMID: 34352421
Yuen HLA, Tran H, Chunilal S
Semin Thromb Hemost 2021 Sep;47(6):677-691. Epub 2021 May 10 doi: 10.1055/s-0041-1725116. PMID: 33971684
Khan O, Marmaro A, Cohen DA
Postgrad Med 2021 Aug;133(sup1):3-10. Epub 2021 Mar 8 doi: 10.1080/00325481.2021.1892390. PMID: 33618595
Cai TY, Rajendran S, Saha P, Dubenec S
Phlebology 2020 Aug;35(7):461-471. Epub 2020 Feb 6 doi: 10.1177/0268355519898920. PMID: 32028850
Kim TI, Sarac TP, Orion KC
Ann Vasc Surg 2019 Jan;54:118-122. Epub 2018 Sep 11 doi: 10.1016/j.avsg.2018.08.077. PMID: 30217714

Diagnosis

Yuen HLA, Tran H, Chunilal S
Semin Thromb Hemost 2021 Sep;47(6):677-691. Epub 2021 May 10 doi: 10.1055/s-0041-1725116. PMID: 33971684
Khan O, Marmaro A, Cohen DA
Postgrad Med 2021 Aug;133(sup1):3-10. Epub 2021 Mar 8 doi: 10.1080/00325481.2021.1892390. PMID: 33618595
Cook JR, Thompson RW
Thorac Surg Clin 2021 Feb;31(1):27-44. doi: 10.1016/j.thorsurg.2020.08.012. PMID: 33220769
Hussain MA, Aljabri B, Al-Omran M
Semin Thorac Cardiovasc Surg 2016 Spring;28(1):151-7. Epub 2015 Oct 28 doi: 10.1053/j.semtcvs.2015.10.008. PMID: 27568153
Moore R, Wei Lum Y
Vasc Med 2015 Apr;20(2):182-9. doi: 10.1177/1358863X14568704. PMID: 25832605

Therapy

Illig KA, Gober L
J Vasc Surg Venous Lymphat Disord 2022 Mar;10(2):514-526. Epub 2021 Aug 2 doi: 10.1016/j.jvsv.2021.07.011. PMID: 34352421
Hoexum F, Jongkind V, Coveliers HM, Yeung KK, Wisselink W
Vascular 2022 Apr;30(2):217-224. Epub 2021 Apr 9 doi: 10.1177/1708538121997332. PMID: 33832359
Cai TY, Rajendran S, Saha P, Dubenec S
Phlebology 2020 Aug;35(7):461-471. Epub 2020 Feb 6 doi: 10.1177/0268355519898920. PMID: 32028850
Madden N, Calligaro KD, Dougherty MJ, Maloni K, Troutman DA
J Vasc Surg Venous Lymphat Disord 2019 Nov;7(6):839-844. Epub 2019 Aug 27 doi: 10.1016/j.jvsv.2019.05.012. PMID: 31471278
Feugier P, Chevalier JM
Acta Chir Belg 2005 May-Jun;105(3):256-64. doi: 10.1080/00015458.2005.11679713. PMID: 16018517

Prognosis

Illig KA, Gober L
J Vasc Surg Venous Lymphat Disord 2022 Mar;10(2):514-526. Epub 2021 Aug 2 doi: 10.1016/j.jvsv.2021.07.011. PMID: 34352421
Illig KA, Rodriguez-Zoppi E
Thorac Surg Clin 2021 Feb;31(1):11-17. doi: 10.1016/j.thorsurg.2020.09.001. PMID: 33220767
Kim TI, Sarac TP, Orion KC
Ann Vasc Surg 2019 Jan;54:118-122. Epub 2018 Sep 11 doi: 10.1016/j.avsg.2018.08.077. PMID: 30217714
Moore R, Wei Lum Y
Vasc Med 2015 Apr;20(2):182-9. doi: 10.1177/1358863X14568704. PMID: 25832605
Feugier P, Chevalier JM
Acta Chir Belg 2005 May-Jun;105(3):256-64. doi: 10.1080/00015458.2005.11679713. PMID: 16018517

Clinical prediction guides

Illig KA, Gober L
J Vasc Surg Venous Lymphat Disord 2022 Mar;10(2):514-526. Epub 2021 Aug 2 doi: 10.1016/j.jvsv.2021.07.011. PMID: 34352421
Khan O, Marmaro A, Cohen DA
Postgrad Med 2021 Aug;133(sup1):3-10. Epub 2021 Mar 8 doi: 10.1080/00325481.2021.1892390. PMID: 33618595
Kim TI, Sarac TP, Orion KC
Ann Vasc Surg 2019 Jan;54:118-122. Epub 2018 Sep 11 doi: 10.1016/j.avsg.2018.08.077. PMID: 30217714
Hussain MA, Aljabri B, Al-Omran M
Semin Thorac Cardiovasc Surg 2016 Spring;28(1):151-7. Epub 2015 Oct 28 doi: 10.1053/j.semtcvs.2015.10.008. PMID: 27568153
Moore R, Wei Lum Y
Vasc Med 2015 Apr;20(2):182-9. doi: 10.1177/1358863X14568704. PMID: 25832605

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