U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Vaginismus

MedGen UID:
412150
Concept ID:
C2004487
Disease or Syndrome; Finding
Synonyms: Colpospasm; Myalgia of pelvic floor; myalgia of pelvic floor; Pelvic floor myalgia; Spasm of vaginal muscles at intercourse; Vaginal spasm; vaginismus; Vaginospasm; Vulvismus
SNOMED CT: Vaginospasm (79012001); Colpospasm (79012001); Vulvismus (79012001); Vaginal spasm (79012001); Spasm of vaginal muscles at intercourse (79012001)
 
HPO: HP:0030017
Monarch Initiative: MONDO:0021723

Definition

Recurrent or persistent involuntary spasms of the musculature of the outer third of the vagina that interferes with vaginal penetration, and which causes personal distress. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Padoa A, McLean L, Morin M, Vandyken C
Sex Med Rev 2021 Jan;9(1):76-92. Epub 2020 Jul 4 doi: 10.1016/j.sxmr.2020.04.002. PMID: 32631813
Wallace SL, Miller LD, Mishra K
Curr Opin Obstet Gynecol 2019 Dec;31(6):485-493. doi: 10.1097/GCO.0000000000000584. PMID: 31609735
Lahaie MA, Boyer SC, Amsel R, Khalifé S, Binik YM
Womens Health (Lond) 2010 Sep;6(5):705-19. doi: 10.2217/whe.10.46. PMID: 20887170

Recent clinical studies

Etiology

Schreiter S, Mascarell-Maricic L, Rakitzis O, Volkmann C, Kaminski J, Daniels MA
Dtsch Arztebl Int 2023 Nov 24;120(47):797-803. doi: 10.3238/arztebl.m2023.0208. PMID: 37732500Free PMC Article
Unlubilgin E, Tetik S, Aksoy I, Yuksel D, Tekin OM
J Sex Med 2021 Oct;18(10):1752-1758. Epub 2021 Aug 18 doi: 10.1016/j.jsxm.2021.07.005. PMID: 34417127
Tetik S, Yalçınkaya Alkar Ö
J Sex Med 2021 Sep;18(9):1555-1570. Epub 2021 Aug 6 doi: 10.1016/j.jsxm.2021.07.004. PMID: 34366265
Hill DA, Taylor CA
Am Fam Physician 2021 May 15;103(10):597-604. PMID: 33983001
Melnik T, Hawton K, McGuire H
Cochrane Database Syst Rev 2012 Dec 12;12(12):CD001760. doi: 10.1002/14651858.CD001760.pub2. PMID: 23235583Free PMC Article

Diagnosis

Tetik S, Yalçınkaya Alkar Ö
J Sex Med 2021 Sep;18(9):1555-1570. Epub 2021 Aug 6 doi: 10.1016/j.jsxm.2021.07.004. PMID: 34366265
Hill DA, Taylor CA
Am Fam Physician 2021 May 15;103(10):597-604. PMID: 33983001
Dias-Amaral A, Marques-Pinto A
Rev Bras Ginecol Obstet 2018 Dec;40(12):787-793. Epub 2018 Nov 14 doi: 10.1055/s-0038-1675805. PMID: 30428492Free PMC Article
Shah M, Hoffstetter S
Obstet Gynecol Clin North Am 2014 Sep;41(3):453-64. Epub 2014 Jul 9 doi: 10.1016/j.ogc.2014.05.005. PMID: 25155125
Lahaie MA, Boyer SC, Amsel R, Khalifé S, Binik YM
Womens Health (Lond) 2010 Sep;6(5):705-19. doi: 10.2217/whe.10.46. PMID: 20887170

Therapy

Shah M, Hoffstetter S
Obstet Gynecol Clin North Am 2014 Sep;41(3):453-64. Epub 2014 Jul 9 doi: 10.1016/j.ogc.2014.05.005. PMID: 25155125
Melnik T, Hawton K, McGuire H
Cochrane Database Syst Rev 2012 Dec 12;12(12):CD001760. doi: 10.1002/14651858.CD001760.pub2. PMID: 23235583Free PMC Article
Lahaie MA, Boyer SC, Amsel R, Khalifé S, Binik YM
Womens Health (Lond) 2010 Sep;6(5):705-19. doi: 10.2217/whe.10.46. PMID: 20887170
McGuire H, Hawton K
Cochrane Database Syst Rev 2003;(1):CD001760. doi: 10.1002/14651858.CD001760. PMID: 12535412
McGuire H, Hawton K
Cochrane Database Syst Rev 2001;(2):CD001760. doi: 10.1002/14651858.CD001760. PMID: 11406006

Prognosis

Zwickl S, Burchill L, Wong AFQ, Leemaqz SY, Cook T, Angus LM, Eshin K, Elder CV, Grover SR, Zajac JD, Cheung AS
LGBT Health 2023 Apr;10(3):179-190. Epub 2023 Jan 4 doi: 10.1089/lgbt.2022.0187. PMID: 36603056Free PMC Article
Banaei M, Kariman N, Ozgoli G, Nasiri M
Reprod Health 2021 Oct 18;18(1):210. doi: 10.1186/s12978-021-01260-2. PMID: 34663378Free PMC Article
Bokaie M, Bostani Khalesi Z
J Sex Marital Ther 2019;45(8):667-672. Epub 2019 Jun 20 doi: 10.1080/0092623X.2019.1610126. PMID: 31007150
Kadir ZS, Sidi H, Kumar J, Das S, Midin M, Baharuddin N
Curr Drug Targets 2018;19(8):916-926. doi: 10.2174/1389450118666170222153908. PMID: 28228081
Reissing ED, Binik YM, Khalifé S
J Nerv Ment Dis 1999 May;187(5):261-74. doi: 10.1097/00005053-199905000-00001. PMID: 10348080

Clinical prediction guides

Krishnappa P, Manfredi C, Jayaramaiah S, Ditonno F, Matippa P, Shah R, Moncada I
J Sex Med 2023 Dec 22;21(1):20-28. doi: 10.1093/jsxmed/qdad146. PMID: 37952223
Banaei M, Kariman N, Ozgoli G, Nasiri M, Roozbeh N, Zare F
J Sex Med 2023 Feb 27;20(3):298-312. doi: 10.1093/jsxmed/qdac049. PMID: 36755511
Unlubilgin E, Tetik S, Aksoy I, Yuksel D, Tekin OM
J Sex Med 2021 Oct;18(10):1752-1758. Epub 2021 Aug 18 doi: 10.1016/j.jsxm.2021.07.005. PMID: 34417127
Tetik S, Yalçınkaya Alkar Ö
J Sex Med 2021 Sep;18(9):1555-1570. Epub 2021 Aug 6 doi: 10.1016/j.jsxm.2021.07.004. PMID: 34366265
Farnam F, Janghorbani M, Merghati-Khoei E, Raisi F
Int J Impot Res 2014 Nov-Dec;26(6):230-4. Epub 2014 May 15 doi: 10.1038/ijir.2014.16. PMID: 24830673

Recent systematic reviews

Pope R, Lee MH, Myers A, Song J, Abou Ghayda R, Kim JY, Hong SH, Lee SB, Koyanagi A, Jacob L, Smith L, Shin JI
J Sex Med 2022 Nov;19(11):1616-1624. Epub 2022 Sep 15 doi: 10.1016/j.jsxm.2022.07.011. PMID: 36115787
Tetik S, Yalçınkaya Alkar Ö
J Sex Med 2021 Sep;18(9):1555-1570. Epub 2021 Aug 6 doi: 10.1016/j.jsxm.2021.07.004. PMID: 34366265
Melnik T, Hawton K, McGuire H
Cochrane Database Syst Rev 2012 Dec 12;12(12):CD001760. doi: 10.1002/14651858.CD001760.pub2. PMID: 23235583Free PMC Article
McGuire H, Hawton K
Cochrane Database Syst Rev 2003;(1):CD001760. doi: 10.1002/14651858.CD001760. PMID: 12535412
McGuire H, Hawton K
Cochrane Database Syst Rev 2001;(2):CD001760. doi: 10.1002/14651858.CD001760. PMID: 11406006

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...