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Glaucoma 1, open angle, O(GLC1O)

MedGen UID:
416515
•Concept ID:
C2751294
•
Disease or Syndrome
Synonym: GLC1O
 
Gene (location): NTF4 (19q13.33)
 
Monarch Initiative: MONDO:0013134
OMIM®: 613100

Definition

Any open-angle glaucoma in which the cause of the disease is a mutation in the NTF4 gene. [from MONDO]

Clinical features

From HPO
Open-angle glaucoma
MedGen UID:
6611
•Concept ID:
C0017612
•
Disease or Syndrome
A type of glaucoma defined by an open, normal appearing anterior chamber angle and raised intraocular pressure,
See: Feature record | Search on this feature

Professional guidelines

PubMed

Evaluation of genetic association of the INK4 locus with primary open angle glaucoma in East Indian population.
Vishal M, Sharma A, Kaurani L, Chakraborty S, Ray J, Sen A, Mukhopadhyay A, Ray K
Sci Rep 2014 May 30;4:5115. doi: 10.1038/srep05115. PMID: 24875940Free PMC Article

Curated

UK NICE Guideline NG81, Glaucoma: diagnosis and management

Recent clinical studies

Therapy

Clinical Assessment of Lamina Cribrosa Curvature in Eyes with Primary Open-Angle Glaucoma.
Kim YW, Jeoung JW, Kim DW, Girard MJ, Mari JM, Park KH, Kim DM
PLoS One 2016;11(3):e0150260. Epub 2016 Mar 10 doi: 10.1371/journal.pone.0150260. PMID: 26963816Free PMC Article
Hemorrhagic descemet membrane detachment after classic canaloplasty.
Brandao LM, Orgul S, Grieshaber MC
Klin Monbl Augenheilkd 2014 Apr;231(4):348-50. Epub 2014 Apr 25 doi: 10.1055/s-0034-1368273. PMID: 24771165

Prognosis

Hemorrhagic descemet membrane detachment after classic canaloplasty.
Brandao LM, Orgul S, Grieshaber MC
Klin Monbl Augenheilkd 2014 Apr;231(4):348-50. Epub 2014 Apr 25 doi: 10.1055/s-0034-1368273. PMID: 24771165

Clinical prediction guides

Lack of Association Between Polymorphism rs4986791 in TLR4 and Primary Open-Angle Glaucoma in a Saudi Cohort.
Mousa A, Kondkar AA, Al-Obeidan SA, Azad TA, Sultan T, Osman EA, Abu-Amero KK
Genet Test Mol Biomarkers 2016 Sep;20(9):556-9. Epub 2016 Aug 15 doi: 10.1089/gtmb.2016.0095. PMID: 27526043
Molecular Analysis of NOTCH2 in Patients with Primary Open-Angle Glaucoma.
Jakobsson C, Kheir V, Munier FL, Schorderet DF
Klin Monbl Augenheilkd 2015 Apr;232(4):427-31. Epub 2015 Apr 22 doi: 10.1055/s-0035-1545781. PMID: 25902091
Evaluation of genetic association of the INK4 locus with primary open angle glaucoma in East Indian population.
Vishal M, Sharma A, Kaurani L, Chakraborty S, Ray J, Sen A, Mukhopadhyay A, Ray K
Sci Rep 2014 May 30;4:5115. doi: 10.1038/srep05115. PMID: 24875940Free PMC Article
Hemorrhagic descemet membrane detachment after classic canaloplasty.
Brandao LM, Orgul S, Grieshaber MC
Klin Monbl Augenheilkd 2014 Apr;231(4):348-50. Epub 2014 Apr 25 doi: 10.1055/s-0034-1368273. PMID: 24771165

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2022
      UK NICE Guideline NG81, Glaucoma: diagnosis and management

    Consumer resources

    Reviews

    Related information

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      Clinical tests in GTR
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      Research tests in GTR
    • MeSH
      Related Medical Subject Headings
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    • OMIM(Genes)
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    • PMC Articles
      Related information in PubMed Central Links
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