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Sick Newborn

MedGen UID:
417237
•Concept ID:
C2825562
•
Finding

Definition

A neonate that is unwell. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSick Newborn

Professional guidelines

PubMed

Expert consensus statement 'Neonatologist-performed Echocardiography (NoPE)'-training and accreditation in UK.
Singh Y, Gupta S, Groves AM, Gandhi A, Thomson J, Qureshi S, Simpson JM
Eur J Pediatr 2016 Feb;175(2):281-7. Epub 2015 Sep 12 doi: 10.1007/s00431-015-2633-2. PMID: 26362538
Diagnosis and management of hypotension in neonates.
Farrugia R, Rojas H, Rabe H
Future Cardiol 2013 Sep;9(5):669-79. doi: 10.2217/fca.13.59. PMID: 24020669
Withholding or withdrawal of life sustaining treatment for newborn infants.
Aladangady N, de Rooy L
Early Hum Dev 2012 Feb;88(2):65-9. Epub 2012 Jan 17 doi: 10.1016/j.earlhumdev.2012.01.002. PMID: 22261290

Recent clinical studies

Etiology

Neonatal inpatient dataset for small and sick newborn care in low- and middle-income countries: systematic development and multi-country operationalisation with NEST360.
Cross JH, Bohne C, Ngwala SK, Shabani J, Wainaina J, Dosunmu O, Kassim I, Penzias RE, Tillya R, Gathara D, Zimba E, Ezeaka VC, Odedere O, Chiume M, Salim N, Kawaza K, Lufesi N, Irimu G, Tongo OO, Malla L, Paton C, Day LT, Oden M, Richards-Kortum R, Molyneux EM, Ohuma EO, Lawn JE; with NEST360 Neonatal Inpatient Dataset Learning Group
BMC Pediatr 2023 Nov 15;23(Suppl 2):567. doi: 10.1186/s12887-023-04341-2. PMID: 37968588Free PMC Article
Use of human milk and fortification in the NICU.
Adamkin DH
J Perinatol 2023 May;43(5):551-559. Epub 2022 Oct 18 doi: 10.1038/s41372-022-01532-0. PMID: 36257977
Prophylactic postnatal corticosteroids: Early hydrocortisone.
Baud O, Watterberg KL
Semin Fetal Neonatal Med 2019 Jun;24(3):202-206. Epub 2019 Apr 20 doi: 10.1016/j.siny.2019.04.007. PMID: 31043325
Introduction to neonatologist-performed echocardiography.
Groves AM, Singh Y, Dempsey E, Molnar Z, Austin T, El-Khuffash A, de Boode WP; European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE)
Pediatr Res 2018 Jul;84(Suppl 1):1-12. doi: 10.1038/s41390-018-0076-y. PMID: 30072808Free PMC Article
Perinatal galactose metabolism.
Kliegman RM, Sparks JW
J Pediatr 1985 Dec;107(6):831-41. doi: 10.1016/s0022-3476(85)80173-6. PMID: 3906069

Diagnosis

Neonatal inpatient dataset for small and sick newborn care in low- and middle-income countries: systematic development and multi-country operationalisation with NEST360.
Cross JH, Bohne C, Ngwala SK, Shabani J, Wainaina J, Dosunmu O, Kassim I, Penzias RE, Tillya R, Gathara D, Zimba E, Ezeaka VC, Odedere O, Chiume M, Salim N, Kawaza K, Lufesi N, Irimu G, Tongo OO, Malla L, Paton C, Day LT, Oden M, Richards-Kortum R, Molyneux EM, Ohuma EO, Lawn JE; with NEST360 Neonatal Inpatient Dataset Learning Group
BMC Pediatr 2023 Nov 15;23(Suppl 2):567. doi: 10.1186/s12887-023-04341-2. PMID: 37968588Free PMC Article
The healthy and sick newborn.
Stanton BF
Pediatr Clin North Am 2015 Apr;62(2):xiii. Epub 2015 Feb 26 doi: 10.1016/j.pcl.2015.01.002. PMID: 25836714
Diagnosis and management of hypotension in neonates.
Farrugia R, Rojas H, Rabe H
Future Cardiol 2013 Sep;9(5):669-79. doi: 10.2217/fca.13.59. PMID: 24020669
Lysosomal storage disorders in the newborn.
Staretz-Chacham O, Lang TC, LaMarca ME, Krasnewich D, Sidransky E
Pediatrics 2009 Apr;123(4):1191-207. doi: 10.1542/peds.2008-0635. PMID: 19336380Free PMC Article
Platelet disorders in newborn infants: diagnosis and management.
Blanchette VS, Rand ML
Semin Perinatol 1997 Feb;21(1):53-62. doi: 10.1016/s0146-0005(97)80020-1. PMID: 9190034

Therapy

The quest for optimum oxygenation during newborn delivery room resuscitation: Is it the baby or is it us?
Sotiropoulos JX, Vento M, Saugstad OD, Oei JL
Semin Perinatol 2022 Oct;46(6):151622. Epub 2022 May 21 doi: 10.1016/j.semperi.2022.151622. PMID: 35725654
Prophylactic postnatal corticosteroids: Early hydrocortisone.
Baud O, Watterberg KL
Semin Fetal Neonatal Med 2019 Jun;24(3):202-206. Epub 2019 Apr 20 doi: 10.1016/j.siny.2019.04.007. PMID: 31043325
Ethics of drug studies in the newborn.
Ward RM, Sherwin CM
Paediatr Drugs 2015 Feb;17(1):37-42. doi: 10.1007/s40272-014-0099-8. PMID: 25354989
How should we manage pain in ventilated neonates?
Menon G, McIntosh N
Neonatology 2008;93(4):316-23. Epub 2008 Jun 5 doi: 10.1159/000121458. PMID: 18525216
Thrombocytopenia in the newborn.
Ramasethu J
Curr Hematol Rep 2004 Mar;3(2):134-42. PMID: 14965490

Prognosis

Investment case for small and sick newborn care in Tanzania: systematic analyses.
Kamuyu R, Tarus A, Bundala F, Msemo G, Shamba D, Paul C, Tillya R, Murless-Collins S, Oden M, Richards-Kortum R, Powell-Jackson T, Kumar MB, Salim N, Lawn JE
BMC Pediatr 2023 Dec 14;23(Suppl 2):632. doi: 10.1186/s12887-023-04414-2. PMID: 38098013Free PMC Article
Ending Preventable Neonatal Deaths: Multicountry Evidence to Inform Accelerated Progress to the Sustainable Development Goal by 2030.
Lawn JE, Bhutta ZA, Ezeaka C, Saugstad O
Neonatology 2023;120(4):491-499. Epub 2023 May 16 doi: 10.1159/000530496. PMID: 37231868Free PMC Article
Reducing newborn mortality in the Asia-Pacific region: Quality hospital services and community-based care.
Milner KM, Duke T, Bucens I
J Paediatr Child Health 2013 Jul;49(7):511-8. Epub 2013 May 28 doi: 10.1111/jpc.12249. PMID: 23713996
An update on ECMO.
Tulenko DR
Neonatal Netw 2004 Jul-Aug;23(4):11-8. doi: 10.1891/0730-0832.23.4.11. PMID: 15317374
Perinatal galactose metabolism.
Kliegman RM, Sparks JW
J Pediatr 1985 Dec;107(6):831-41. doi: 10.1016/s0022-3476(85)80173-6. PMID: 3906069

Clinical prediction guides

Neonatal inpatient dataset for small and sick newborn care in low- and middle-income countries: systematic development and multi-country operationalisation with NEST360.
Cross JH, Bohne C, Ngwala SK, Shabani J, Wainaina J, Dosunmu O, Kassim I, Penzias RE, Tillya R, Gathara D, Zimba E, Ezeaka VC, Odedere O, Chiume M, Salim N, Kawaza K, Lufesi N, Irimu G, Tongo OO, Malla L, Paton C, Day LT, Oden M, Richards-Kortum R, Molyneux EM, Ohuma EO, Lawn JE; with NEST360 Neonatal Inpatient Dataset Learning Group
BMC Pediatr 2023 Nov 15;23(Suppl 2):567. doi: 10.1186/s12887-023-04341-2. PMID: 37968588Free PMC Article
Quality of care assessment for small and sick newborns and young infants in Pakistan: findings from a cross-sectional study.
Pradhan NA, Ali SA, Roujani S, Ali A, Hussain SS, Rizwan S, Ariff S, Saleem S, Siddiqi S
BMC Pediatr 2022 Jan 29;22(1):68. doi: 10.1186/s12887-022-03108-5. PMID: 35093035Free PMC Article
Neonatalogist-performed echography in neonatology: a Tunisian experience.
Chioukh FZ, Khemis T, Bahri J, Chaabane A, Hamdi S, Maatouk F, Néffati E, Boughzéla E, Kortas C, Ben Ameur K, Monastiri K
Tunis Med 2019 Jan;97(1):122-127. PMID: 31535703
Efficacy and acceptability of an "App on sick newborn care" in physicians from newborn units.
Prakash V, Thukral A, Sankar MJ, Agarwal RK, Paul VK, Deorari AK
BMC Med Educ 2016 Mar 8;16:84. doi: 10.1186/s12909-016-0579-3. PMID: 26956397Free PMC Article
Pharmacology of diuretics in the newborn.
Chemtob S, Kaplan BS, Sherbotie JR, Aranda JV
Pediatr Clin North Am 1989 Oct;36(5):1231-50. doi: 10.1016/s0031-3955(16)36766-9. PMID: 2677940

Recent systematic reviews

Higher versus lower amino acid intake in parenteral nutrition for newborn infants.
Osborn DA, Schindler T, Jones LJ, Sinn JK, Bolisetty S
Cochrane Database Syst Rev 2018 Mar 5;3(3):CD005949. doi: 10.1002/14651858.CD005949.pub2. PMID: 29505664Free PMC Article

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