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T Waves Flat by ECG Finding

MedGen UID:
418086
•Concept ID:
C2348640
•
Finding
Synonyms: T Waves Flat; T Waves Flat by EKG Finding

Definition

An electrocardiographic finding in which the T wave appears decreased in amplitude. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVT Waves Flat by ECG Finding

Recent clinical studies

Etiology

Anatomical considerations and clinical interpretation of the 12-lead ECG in the prone position: a prospective multicentre study.
Romero J, Garcia M, Diaz JC, Gabr M, Rodriguez-Taveras J, Braunstein ED, Purkayastha S, Gamero MT, Alviz I, Marín J, Aristizábal J, Reynbakh O, Peralta AO, Duque M, Dave KP, Rodriguez D, Nino C, Briceno D, Velasco A, Ferrick K, Slipczuk L, Natale A, Di Biase L
Europace 2023 Feb 8;25(1):175-184. doi: 10.1093/europace/euac099. PMID: 36196043Free PMC Article
Prognostic significance of flat T-waves in the lateral leads in general population.
Holkeri A, Eranti A, Haukilahti MAE, Kerola T, Kenttä TV, Noponen K, Seppänen T, Rissanen H, Heliövaara M, Knekt P, Junttila MJ, Huikuri HV, Aro AL
J Electrocardiol 2021 Nov-Dec;69:105-110. Epub 2021 Oct 9 doi: 10.1016/j.jelectrocard.2021.10.001. PMID: 34656915
Coronary Sinus Activation and ECG Characteristics of Roof-Dependent Left Atrial Flutter After Pulmonary Vein Isolation.
Casado Arroyo R, Laţcu DG, Maeda S, Kubala M, Santangeli P, Garcia FC, Enache B, Eljamili M, Hayashi T, Zado ES, Saoudi N, Marchlinski FE
Circ Arrhythm Electrophysiol 2018 Jun;11(6):e005948. doi: 10.1161/CIRCEP.117.005948. PMID: 29858383
The algorithmic performance of J-Tpeak for drug safety clinical trial.
Chien SC, Gregg RE
J Electrocardiol 2017 Nov-Dec;50(6):762-768. Epub 2017 Aug 15 doi: 10.1016/j.jelectrocard.2017.08.018. PMID: 28942951
Athlete's heart electrocardiogram mimicking hypertrophic cardiomyopathy.
Pelliccia A, Maron BJ
Curr Cardiol Rep 2001 Mar;3(2):147-51. doi: 10.1007/s11886-001-0042-9. PMID: 11177673

Diagnosis

Action potential morphology affects T-wave symmetry (simulation study).
Arteyeva NV, Komarov IA, Azarov JE
J Electrocardiol 2023 Nov-Dec;81:237-243. Epub 2023 Oct 12 doi: 10.1016/j.jelectrocard.2023.10.004. PMID: 37844373
Coronary Sinus Activation and ECG Characteristics of Roof-Dependent Left Atrial Flutter After Pulmonary Vein Isolation.
Casado Arroyo R, Laţcu DG, Maeda S, Kubala M, Santangeli P, Garcia FC, Enache B, Eljamili M, Hayashi T, Zado ES, Saoudi N, Marchlinski FE
Circ Arrhythm Electrophysiol 2018 Jun;11(6):e005948. doi: 10.1161/CIRCEP.117.005948. PMID: 29858383
The algorithmic performance of J-Tpeak for drug safety clinical trial.
Chien SC, Gregg RE
J Electrocardiol 2017 Nov-Dec;50(6):762-768. Epub 2017 Aug 15 doi: 10.1016/j.jelectrocard.2017.08.018. PMID: 28942951
The development and validation of an easy to use automatic QT-interval algorithm.
Hermans BJM, Vink AS, Bennis FC, Filippini LH, Meijborg VMF, Wilde AAM, Pison L, Postema PG, Delhaas T
PLoS One 2017;12(9):e0184352. Epub 2017 Sep 1 doi: 10.1371/journal.pone.0184352. PMID: 28863167Free PMC Article
Athlete's heart electrocardiogram mimicking hypertrophic cardiomyopathy.
Pelliccia A, Maron BJ
Curr Cardiol Rep 2001 Mar;3(2):147-51. doi: 10.1007/s11886-001-0042-9. PMID: 11177673

Therapy

T-wave morphology abnormalities in the STREAM stage 1 trial.
Hughes G, Young WJ, Bern H, Crook A, Lambiase PD, Goodall RL, Nunn AJ, Meredith SK
Expert Opin Drug Saf 2024 Apr;23(4):469-476. Epub 2024 Mar 10 doi: 10.1080/14740338.2024.2322116. PMID: 38462751
Coronary Sinus Activation and ECG Characteristics of Roof-Dependent Left Atrial Flutter After Pulmonary Vein Isolation.
Casado Arroyo R, Laţcu DG, Maeda S, Kubala M, Santangeli P, Garcia FC, Enache B, Eljamili M, Hayashi T, Zado ES, Saoudi N, Marchlinski FE
Circ Arrhythm Electrophysiol 2018 Jun;11(6):e005948. doi: 10.1161/CIRCEP.117.005948. PMID: 29858383
The algorithmic performance of J-Tpeak for drug safety clinical trial.
Chien SC, Gregg RE
J Electrocardiol 2017 Nov-Dec;50(6):762-768. Epub 2017 Aug 15 doi: 10.1016/j.jelectrocard.2017.08.018. PMID: 28942951
The development and validation of an easy to use automatic QT-interval algorithm.
Hermans BJM, Vink AS, Bennis FC, Filippini LH, Meijborg VMF, Wilde AAM, Pison L, Postema PG, Delhaas T
PLoS One 2017;12(9):e0184352. Epub 2017 Sep 1 doi: 10.1371/journal.pone.0184352. PMID: 28863167Free PMC Article
Relation of electrocardiographic left ventricular hypertrophy with and without T-wave changes to systemic blood pressure, body mass, and serum lipids and blood glucose levels in Japanese men.
Ichihara Y, Sugino M, Hattori R, Anno T, Mizuno Y, Yokoi M, Kondo T, Hirai M, Kawamura T
Am J Cardiol 1997 Sep 15;80(6):730-5. doi: 10.1016/s0002-9149(97)00504-3. PMID: 9315578

Prognosis

Electrocardiogram Fiducial Point Detector Using a Bilateral Filter and Symmetrical Point-Filter Structure.
Bae TW, Kwon KK, Kim KH
Int J Environ Res Public Health 2021 Oct 14;18(20) doi: 10.3390/ijerph182010792. PMID: 34682541Free PMC Article
Prognostic significance of flat T-waves in the lateral leads in general population.
Holkeri A, Eranti A, Haukilahti MAE, Kerola T, Kenttä TV, Noponen K, Seppänen T, Rissanen H, Heliövaara M, Knekt P, Junttila MJ, Huikuri HV, Aro AL
J Electrocardiol 2021 Nov-Dec;69:105-110. Epub 2021 Oct 9 doi: 10.1016/j.jelectrocard.2021.10.001. PMID: 34656915
Pseudo-sawtooth pattern on amplitude-integrated electroencephalography in neonatal hypoxic-ischemic encephalopathy.
Tanaka M, Kidokoro H, Kubota T, Fukasawa T, Okai Y, Sakaguchi Y, Ito Y, Yamamoto H, Ohno A, Nakata T, Negoro T, Okumura A, Kato T, Watanabe K, Takahashi Y, Natsume J
Pediatr Res 2020 Feb;87(3):529-535. Epub 2019 Sep 7 doi: 10.1038/s41390-019-0567-5. PMID: 31493771
Coronary Sinus Activation and ECG Characteristics of Roof-Dependent Left Atrial Flutter After Pulmonary Vein Isolation.
Casado Arroyo R, Laţcu DG, Maeda S, Kubala M, Santangeli P, Garcia FC, Enache B, Eljamili M, Hayashi T, Zado ES, Saoudi N, Marchlinski FE
Circ Arrhythm Electrophysiol 2018 Jun;11(6):e005948. doi: 10.1161/CIRCEP.117.005948. PMID: 29858383
Isolated negative T waves as independent predictors of short-term and long-term coronary heart disease mortality in men free of manifest heart disease in the Seven Countries Study.
Rautaharju PM, Menotti A, Blackburn H, Parapid B, Kircanski B
J Electrocardiol 2012 Nov-Dec;45(6):717-22. Epub 2012 Sep 8 doi: 10.1016/j.jelectrocard.2012.07.006. PMID: 22964131

Clinical prediction guides

Anatomical considerations and clinical interpretation of the 12-lead ECG in the prone position: a prospective multicentre study.
Romero J, Garcia M, Diaz JC, Gabr M, Rodriguez-Taveras J, Braunstein ED, Purkayastha S, Gamero MT, Alviz I, Marín J, Aristizábal J, Reynbakh O, Peralta AO, Duque M, Dave KP, Rodriguez D, Nino C, Briceno D, Velasco A, Ferrick K, Slipczuk L, Natale A, Di Biase L
Europace 2023 Feb 8;25(1):175-184. doi: 10.1093/europace/euac099. PMID: 36196043Free PMC Article
Electrocardiogram Fiducial Point Detector Using a Bilateral Filter and Symmetrical Point-Filter Structure.
Bae TW, Kwon KK, Kim KH
Int J Environ Res Public Health 2021 Oct 14;18(20) doi: 10.3390/ijerph182010792. PMID: 34682541Free PMC Article
Prognostic significance of flat T-waves in the lateral leads in general population.
Holkeri A, Eranti A, Haukilahti MAE, Kerola T, Kenttä TV, Noponen K, Seppänen T, Rissanen H, Heliövaara M, Knekt P, Junttila MJ, Huikuri HV, Aro AL
J Electrocardiol 2021 Nov-Dec;69:105-110. Epub 2021 Oct 9 doi: 10.1016/j.jelectrocard.2021.10.001. PMID: 34656915
The development and validation of an easy to use automatic QT-interval algorithm.
Hermans BJM, Vink AS, Bennis FC, Filippini LH, Meijborg VMF, Wilde AAM, Pison L, Postema PG, Delhaas T
PLoS One 2017;12(9):e0184352. Epub 2017 Sep 1 doi: 10.1371/journal.pone.0184352. PMID: 28863167Free PMC Article
Athlete's heart electrocardiogram mimicking hypertrophic cardiomyopathy.
Pelliccia A, Maron BJ
Curr Cardiol Rep 2001 Mar;3(2):147-51. doi: 10.1007/s11886-001-0042-9. PMID: 11177673

Recent systematic reviews

Evaluation of the QT interval in patients with drug-induced QT prolongation and torsades de pointes.
Krisai P, Vlachos K, Ramirez FD, Nakatani Y, Nakashima T, Takagi T, Kamakura T, Surget E, André C, Cheniti G, Welte N, Chauvel R, Tixier R, Duchateau J, Pambrun T, Derval N, Hocini M, Jaïs P, Haïssaguerre M, Sacher F
J Cardiovasc Electrophysiol 2020 Oct;31(10):2696-2701. Epub 2020 Jul 28 doi: 10.1111/jce.14687. PMID: 32700358

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