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del(12p13)

MedGen UID:
419167
•Concept ID:
C2931806
•
Cell or Molecular Dysfunction
Synonyms: Deletion 12p13; Monosomy 12p13

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVdel(12p13)

Recent clinical studies

Etiology

Heterogeneous chromosome 12p deletion is an independent adverse prognostic factor and resistant to bortezomib-based therapy in multiple myeloma.
Li F, Xu Y, Deng P, Yang Y, Sui W, Jin F, Hao M, Li Z, Zang M, Zhou D, Gu Z, Ru K, Wang J, Cheng T, Qiu L
Oncotarget 2015 Apr 20;6(11):9434-44. doi: 10.18632/oncotarget.3319. PMID: 25831238Free PMC Article

Diagnosis

Heterogeneous chromosome 12p deletion is an independent adverse prognostic factor and resistant to bortezomib-based therapy in multiple myeloma.
Li F, Xu Y, Deng P, Yang Y, Sui W, Jin F, Hao M, Li Z, Zang M, Zhou D, Gu Z, Ru K, Wang J, Cheng T, Qiu L
Oncotarget 2015 Apr 20;6(11):9434-44. doi: 10.18632/oncotarget.3319. PMID: 25831238Free PMC Article
Prognostic significance of copy-number alterations in multiple myeloma.
Avet-Loiseau H, Li C, Magrangeas F, Gouraud W, Charbonnel C, Harousseau JL, Attal M, Marit G, Mathiot C, Facon T, Moreau P, Anderson KC, Campion L, Munshi NC, Minvielle S
J Clin Oncol 2009 Sep 20;27(27):4585-90. Epub 2009 Aug 17 doi: 10.1200/JCO.2008.20.6136. PMID: 19687334Free PMC Article

Therapy

Heterogeneous chromosome 12p deletion is an independent adverse prognostic factor and resistant to bortezomib-based therapy in multiple myeloma.
Li F, Xu Y, Deng P, Yang Y, Sui W, Jin F, Hao M, Li Z, Zang M, Zhou D, Gu Z, Ru K, Wang J, Cheng T, Qiu L
Oncotarget 2015 Apr 20;6(11):9434-44. doi: 10.18632/oncotarget.3319. PMID: 25831238Free PMC Article

Prognosis

Heterogeneous chromosome 12p deletion is an independent adverse prognostic factor and resistant to bortezomib-based therapy in multiple myeloma.
Li F, Xu Y, Deng P, Yang Y, Sui W, Jin F, Hao M, Li Z, Zang M, Zhou D, Gu Z, Ru K, Wang J, Cheng T, Qiu L
Oncotarget 2015 Apr 20;6(11):9434-44. doi: 10.18632/oncotarget.3319. PMID: 25831238Free PMC Article
Prognostic significance of copy-number alterations in multiple myeloma.
Avet-Loiseau H, Li C, Magrangeas F, Gouraud W, Charbonnel C, Harousseau JL, Attal M, Marit G, Mathiot C, Facon T, Moreau P, Anderson KC, Campion L, Munshi NC, Minvielle S
J Clin Oncol 2009 Sep 20;27(27):4585-90. Epub 2009 Aug 17 doi: 10.1200/JCO.2008.20.6136. PMID: 19687334Free PMC Article

Clinical prediction guides

Prognostic significance of copy-number alterations in multiple myeloma.
Avet-Loiseau H, Li C, Magrangeas F, Gouraud W, Charbonnel C, Harousseau JL, Attal M, Marit G, Mathiot C, Facon T, Moreau P, Anderson KC, Campion L, Munshi NC, Minvielle S
J Clin Oncol 2009 Sep 20;27(27):4585-90. Epub 2009 Aug 17 doi: 10.1200/JCO.2008.20.6136. PMID: 19687334Free PMC Article

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