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Fascioliasis

MedGen UID:
41969
Concept ID:
C0015652
Disease or Syndrome
Synonyms: Fasciola Infection; Fasciola Infections; Fascioliases; Infection, Fasciola; Infections, Fasciola
SNOMED CT: Infection by Fasciola (111922007); Fascioliasis (111922007); Infection caused by Fasciola (111922007)
 
Monarch Initiative: MONDO:0004668

Definition

A parasitic infection that is caused by liver flukes, usually Fasciola hepatica, of sheep, goats, and cattle. Humans become infected by eating uncooked, infested aquatic vegetation (classically watercress). Adult flukes inhabit the bile ducts, gallbladder, and occasionally ectopic sites. Symptoms arise secondary to inflammatory response or obstruction. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFascioliasis

Professional guidelines

PubMed

Marcos L, Maco V, Terashima A
Expert Rev Anti Infect Ther 2021 Jul;19(7):817-823. Epub 2020 Dec 14 doi: 10.1080/14787210.2021.1858798. PMID: 33267701
Gandhi P, Schmitt EK, Chen CW, Samantray S, Venishetty VK, Hughes D
Trans R Soc Trop Med Hyg 2019 Dec 1;113(12):797-804. doi: 10.1093/trstmh/trz093. PMID: 31638149Free PMC Article
Webb CM, Cabada MM
Curr Opin Infect Dis 2018 Oct;31(5):409-414. doi: 10.1097/QCO.0000000000000482. PMID: 30113327

Recent clinical studies

Etiology

Wszelaki S, Podobiński P, Środoń K
J Appl Toxicol 2023 Dec;43(12):1778-1792. Epub 2023 Apr 1 doi: 10.1002/jat.4466. PMID: 36987554
Thakare R, Dasgupta A, Chopra S
Drugs Today (Barc) 2019 Dec;55(12):743-752. doi: 10.1358/dot.2019.55.12.3058861. PMID: 31942877
Ai L, Chen JX, Cai YC, Lu Y, Chu YH, Chen SH, Li H, Song P, Chen MX, Zhou XN
Acta Trop 2019 Aug;196:180-188. Epub 2019 May 8 doi: 10.1016/j.actatropica.2019.05.007. PMID: 31077642
Bergquist R, Brattig NW, Chimbari MJ, Zinsstag J, Utzinger J
Acta Trop 2017 Nov;175:1-8. Epub 2017 Jul 18 doi: 10.1016/j.actatropica.2017.07.015. PMID: 28733024
Dietrich CF, Kabaalioglu A, Brunetti E, Richter J
Z Gastroenterol 2015 Apr;53(4):285-90. Epub 2015 Apr 10 doi: 10.1055/s-0034-1385728. PMID: 25860578

Diagnosis

Lalrinkima H, Lalchhandama C, Jacob SS, Raina OK, Lallianchhunga MC
Exp Parasitol 2021 Mar;222:108066. Epub 2021 Jan 12 doi: 10.1016/j.exppara.2021.108066. PMID: 33444570
Siles-Lucas M, Becerro-Recio D, Serrat J, González-Miguel J
Res Vet Sci 2021 Jan;134:27-35. Epub 2020 Oct 17 doi: 10.1016/j.rvsc.2020.10.011. PMID: 33278757
Ai L, Chen JX, Cai YC, Lu Y, Chu YH, Chen SH, Li H, Song P, Chen MX, Zhou XN
Acta Trop 2019 Aug;196:180-188. Epub 2019 May 8 doi: 10.1016/j.actatropica.2019.05.007. PMID: 31077642
Harrington D, Lamberton PHL, McGregor A
Lancet Gastroenterol Hepatol 2017 Sep;2(9):680-689. doi: 10.1016/S2468-1253(17)30111-5. PMID: 28786389
Saba R, Korkmaz M, Inan D, Mamikoğlu L, Turhan O, Günseren F, Cevikol C, Kabaalioğlu A
Clin Microbiol Infect 2004 May;10(5):385-7. doi: 10.1111/j.1469-0691.2004.00820.x. PMID: 15113313

Therapy

Chai JY, Jung BK, Hong SJ
Korean J Parasitol 2021 Jun;59(3):189-225. Epub 2021 Jun 21 doi: 10.3347/kjp.2021.59.3.189. PMID: 34218593Free PMC Article
Ekpanyapong S, Reddy KR
Gastroenterol Clin North Am 2020 Jun;49(2):379-410. doi: 10.1016/j.gtc.2020.01.009. PMID: 32389369
Mas-Coma S, Valero MA, Bargues MD
Adv Exp Med Biol 2014;766:77-114. doi: 10.1007/978-1-4939-0915-5_4. PMID: 24903364
Saba R, Korkmaz M, Inan D, Mamikoğlu L, Turhan O, Günseren F, Cevikol C, Kabaalioğlu A
Clin Microbiol Infect 2004 May;10(5):385-7. doi: 10.1111/j.1469-0691.2004.00820.x. PMID: 15113313
Osman M, Lausten SB, El-Sefi T, Boghdadi I, Rashed MY, Jensen SL
Dig Surg 1998;15(4):287-96. doi: 10.1159/000018640. PMID: 9845601

Prognosis

Mas-Coma S, Bargues MD, Valero MA
Parasitology 2018 Nov;145(13):1665-1699. Epub 2018 Jul 11 doi: 10.1017/S0031182018000914. PMID: 29991363
Lupi O, Downing C, Lee M, Bravo F, Giglio P, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):947-57; quiz 957-8. doi: 10.1016/j.jaad.2014.11.035. PMID: 26568338
Lupi O, Downing C, Lee M, Pino L, Bravo F, Giglio P, Sethi A, Klaus S, Sangueza OP, Fuller C, Mendoza N, Ladizinski B, Woc-Colburn L, Tyring SK
J Am Acad Dermatol 2015 Dec;73(6):929-44; quiz 945-6. doi: 10.1016/j.jaad.2014.11.034. PMID: 26568337
Mas-Coma S, Agramunt VH, Valero MA
Adv Parasitol 2014;84:27-149. doi: 10.1016/B978-0-12-800099-1.00002-8. PMID: 24480313
Osman M, Lausten SB, El-Sefi T, Boghdadi I, Rashed MY, Jensen SL
Dig Surg 1998;15(4):287-96. doi: 10.1159/000018640. PMID: 9845601

Clinical prediction guides

Leerapun A, Puasripun S, Kijdamrongthum P, Thongsawat S
Hepatol Int 2021 Jun;15(3):804-811. Epub 2021 Apr 17 doi: 10.1007/s12072-021-10180-z. PMID: 33866512
Corral-Ruiz GM, Sánchez-Torres LE
Acta Trop 2020 Oct;210:105548. Epub 2020 Jun 4 doi: 10.1016/j.actatropica.2020.105548. PMID: 32505597
Cabada MM, White AC Jr
Curr Opin Infect Dis 2012 Oct;25(5):518-22. doi: 10.1097/QCO.0b013e3283567b7e. PMID: 22744320
Mera y Sierra R, Agramunt VH, Cuervo P, Mas-Coma S
Parasit Vectors 2011 Jun 11;4:104. doi: 10.1186/1756-3305-4-104. PMID: 21663691Free PMC Article
García-Rodriguez JA, Martin Sánchez AM, Fernández Gorostarzu JM, García Luis EJ
Eur J Epidemiol 1985 Jun;1(2):121-6. doi: 10.1007/BF00141804. PMID: 3916096

Recent systematic reviews

Qian MB, Patel C, Palmeirim MS, Wang X, Schindler C, Utzinger J, Zhou XN, Keiser J
Lancet Microbe 2022 Aug;3(8):e616-e624. Epub 2022 Jun 10 doi: 10.1016/S2666-5247(22)00026-X. PMID: 35697047
Dermauw V, Muchai J, Al Kappany Y, Fajardo Castaneda AL, Dorny P
PLoS One 2021;16(12):e0261166. Epub 2021 Dec 9 doi: 10.1371/journal.pone.0261166. PMID: 34882738Free PMC Article
Taghipour A, Zaki L, Rostami A, Foroutan M, Ghaffarifar F, Fathi A, Abdoli A
Infect Dis (Lond) 2019 Nov-Dec;51(11-12):785-792. Epub 2019 Sep 11 doi: 10.1080/23744235.2019.1663362. PMID: 31507248
Bahmaninejad P, Abdi J, Valizadeh R
Infect Disord Drug Targets 2019;19(1):30-35. doi: 10.2174/1871526518666180816102040. PMID: 30113004
Xia J, Jiang SC, Peng HJ
PLoS One 2015;10(7):e0132673. Epub 2015 Jul 17 doi: 10.1371/journal.pone.0132673. PMID: 26186510Free PMC Article

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