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Anaplastic Plasmacytoma

MedGen UID:
419825
•Concept ID:
C2931517
•
Neoplastic Process
Synonyms: Anaplastic skeletal plasmacytoma (type); Anaplastic solitary extramedullary plasmacytoma of the cecum (type); Extramedullary anaplastic plasmacytoma (type); Plasmacytoma anaplastic

Definition

A plasmacytoma characterized by the presence of malignant plasma cells with anaplastic features. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnaplastic Plasmacytoma

Professional guidelines

PubMed

Differential diagnosis of malignant lymphomas and related disorders by specific pattern of expression of immunophenotypic markers revealed by multiparameter flow cytometry (Review).
Weisberger J, Wu CD, Liu Z, Wong JY, Melamed MR, Darzynkiewicz Z, Gorczyca W
Int J Oncol 2000 Dec;17(6):1165-77. doi: 10.3892/ijo.17.6.1165. PMID: 11078802

Recent clinical studies

Etiology

Epstein-Barr virus-associated high-grade anaplastic plasmacytoma in a renal transplant patient.
Papadaki HA, Stefanaki K, Kanavaros P, Katonis P, Papastathi H, Valatas W, Stylianoy K, Eliopoulos GD
Leuk Lymphoma 2000 Jan;36(3-4):411-5. doi: 10.3109/10428190009148863. PMID: 10674914
Primary spinal epidural manifestation of malignant lymphoma.
Schwechheimer K, Hashemian A, Ott G, Müller-Hermelink HK
Histopathology 1996 Sep;29(3):265-9. doi: 10.1111/j.1365-2559.1996.tb01401.x. PMID: 8884356
Plasma cell myeloma in patients who are HIV-positive.
Kumar S, Kumar D, Schnadig VJ, Selvanayagam P, Slaughter DP
Am J Clin Pathol 1994 Nov;102(5):633-9. doi: 10.1093/ajcp/102.5.633. PMID: 7942629

Diagnosis

Plasmacytoma of the Head and Neck: Case Series and Review of the Literature.
Lamb MM, Zeatoun A, Stack TJ, Kim S, Albastoni S, Singer B, Klatt-Cromwell C, Senior BA, Kimple AJ, Thorp BD
ORL J Otorhinolaryngol Relat Spec 2023;85(4):231-237. Epub 2023 Jun 26 doi: 10.1159/000530946. PMID: 37364541
Rare case of anaplastic plasmacytoma in the sinonasal tract.
Xing MH, Shaari AL, Beute JE, Mundi N, Matloob A, Khorsandi AS, Wisdom G, Urken ML
Head Neck 2021 Oct;43(10):E46-E50. Epub 2021 Jul 17 doi: 10.1002/hed.26818. PMID: 34272912
Anaplastic plasmacytoma: a rare tumor presenting as a pathological fracture in a younger adult.
Morris RW, Kumar V, Saad AG
Skeletal Radiol 2018 Jul;47(7):995-1001. Epub 2018 Jan 31 doi: 10.1007/s00256-018-2884-x. PMID: 29388036
Primary spinal epidural manifestation of malignant lymphoma.
Schwechheimer K, Hashemian A, Ott G, Müller-Hermelink HK
Histopathology 1996 Sep;29(3):265-9. doi: 10.1111/j.1365-2559.1996.tb01401.x. PMID: 8884356
Plasma cell myeloma in patients who are HIV-positive.
Kumar S, Kumar D, Schnadig VJ, Selvanayagam P, Slaughter DP
Am J Clin Pathol 1994 Nov;102(5):633-9. doi: 10.1093/ajcp/102.5.633. PMID: 7942629

Therapy

Brain necrosis after permanent low-activity iodine-125 implants: case report and review of toxicity from focal radiation.
Bampoe J, Nag S, Leung P, Laperriere N, Bernstein M
Brain Tumor Pathol 2000;17(3):139-45. doi: 10.1007/BF02484285. PMID: 11310921
Epstein-Barr virus-associated high-grade anaplastic plasmacytoma in a renal transplant patient.
Papadaki HA, Stefanaki K, Kanavaros P, Katonis P, Papastathi H, Valatas W, Stylianoy K, Eliopoulos GD
Leuk Lymphoma 2000 Jan;36(3-4):411-5. doi: 10.3109/10428190009148863. PMID: 10674914

Prognosis

Plasmacytoma of the Head and Neck: Case Series and Review of the Literature.
Lamb MM, Zeatoun A, Stack TJ, Kim S, Albastoni S, Singer B, Klatt-Cromwell C, Senior BA, Kimple AJ, Thorp BD
ORL J Otorhinolaryngol Relat Spec 2023;85(4):231-237. Epub 2023 Jun 26 doi: 10.1159/000530946. PMID: 37364541
Rare case of anaplastic plasmacytoma in the sinonasal tract.
Xing MH, Shaari AL, Beute JE, Mundi N, Matloob A, Khorsandi AS, Wisdom G, Urken ML
Head Neck 2021 Oct;43(10):E46-E50. Epub 2021 Jul 17 doi: 10.1002/hed.26818. PMID: 34272912
Retroperitoneal extramedullary anaplastic plasmacytoma masquerading as sarcoma: Report of a case with an unusual presentation and imprint smears.
Khayyata S, Bentley G, Fregene TA, Al-Abbadi M
Acta Cytol 2007 May-Jun;51(3):434-6. doi: 10.1159/000325761. PMID: 17536549
Chronic idiopathic myelofibrosis terminating in extramedullary anaplastic plasmacytoma.
Liu ML, Kallakury B, Kessler C, Hartmann DP, Azumi N, Ozdemirli M
Leuk Lymphoma 2006 Feb;47(2):315-22. doi: 10.1080/10428190500286358. PMID: 16321864
Brain necrosis after permanent low-activity iodine-125 implants: case report and review of toxicity from focal radiation.
Bampoe J, Nag S, Leung P, Laperriere N, Bernstein M
Brain Tumor Pathol 2000;17(3):139-45. doi: 10.1007/BF02484285. PMID: 11310921

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