U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fox-Fordyce disease

MedGen UID:
42092
Concept ID:
C0016632
Disease or Syndrome
Synonyms: Fox-Fordyce syndrome; Miliaria, apocrine
SNOMED CT: Fox-Fordyce disease (65038009); Apocrine miliaria (65038009); Fox Fordyce disease (65038009)
 
Monarch Initiative: MONDO:0006553

Definition

A chronic inflammatory skin disorder characterized by pruritic papular eruptions in areas with apocrine glands. It usually affects the axillae bilaterally. There is rupture of the apocrine ducts resulting in inflammation and formation of the papular skin lesions. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFox-Fordyce disease

Professional guidelines

PubMed

Salloum A, Bouferraa Y, Bazzi N, Bou Zerdan M, Abi Chebl J, Chu T, Bachour J, Benedetto A
J Cosmet Dermatol 2022 Feb;21(2):482-500. Epub 2021 Apr 18 doi: 10.1111/jocd.14135. PMID: 33817950
Klager S, Kumar MG
Pediatr Dermatol 2021 Jul;38(4):950-951. Epub 2021 Jun 1 doi: 10.1111/pde.14552. PMID: 34060125
Pinkus H
JAMA 1973 Feb 19;223(8):924. doi: 10.1001/jama.1973.03220080054025. PMID: 4739247

Recent clinical studies

Etiology

Alikhan A, Gorouhi F, Zargari O
Pediatr Dermatol 2010 Mar-Apr;27(2):162-5. doi: 10.1111/j.1525-1470.2010.01102.x. PMID: 20537067
Kamada A, Saga K, Jimbow K
J Am Acad Dermatol 2003 Mar;48(3):453-5. doi: 10.1067/mjd.2003.93. PMID: 12637930
Pasricha JS, Nayyar KC
Dermatologica 1973;147(4):271-3. doi: 10.1159/000251880. PMID: 4780778

Diagnosis

Salloum A, Bouferraa Y, Bazzi N, Bou Zerdan M, Abi Chebl J, Chu T, Bachour J, Benedetto A
J Cosmet Dermatol 2022 Feb;21(2):482-500. Epub 2021 Apr 18 doi: 10.1111/jocd.14135. PMID: 33817950
Yang CS, Teeple M, Muglia J, Robinson-Bostom L
Clin Dermatol 2016 May-Jun;34(3):335-43. Epub 2016 Feb 11 doi: 10.1016/j.clindermatol.2016.02.005. PMID: 27265071
Brau Javier CN, Morales A, Sanchez JL
Int J Dermatol 2012 Nov;51(11):1313-8. doi: 10.1111/j.1365-4632.2011.05236.x. PMID: 23067079
Kao PH, Hsu CK, Lee JY
J Dermatol 2009 Sep;36(9):485-90. doi: 10.1111/j.1346-8138.2009.00689.x. PMID: 19712275
Helm TN, Chen PW
Cutis 2002 May;69(5):335, 342. PMID: 12041809

Therapy

Mallat F, Chaaya C, Aoun M, Soutou B, Helou J
J Cutan Med Surg 2023 Jul-Aug;27(4):375-387. Epub 2023 Jun 5 doi: 10.1177/12034754231174852. PMID: 37272371
Salloum A, Bouferraa Y, Bazzi N, Bou Zerdan M, Abi Chebl J, Chu T, Bachour J, Benedetto A
J Cosmet Dermatol 2022 Feb;21(2):482-500. Epub 2021 Apr 18 doi: 10.1111/jocd.14135. PMID: 33817950
Sammour R, Nasser S, Debahy N, El Habr C
J Eur Acad Dermatol Venereol 2016 Sep;30(9):1578-82. Epub 2016 May 2 doi: 10.1111/jdv.13680. PMID: 27135989
Yost J, Robinson M, Meehan SA
Dermatol Online J 2012 Dec 15;18(12):28. PMID: 23286818
Shackelton J, English JC 3rd
J Pediatr Adolesc Gynecol 2011 Jun;24(3):108-9. doi: 10.1016/j.jpag.2011.03.005. PMID: 21751451

Prognosis

Salloum A, Bouferraa Y, Bazzi N, Bou Zerdan M, Abi Chebl J, Chu T, Bachour J, Benedetto A
J Cosmet Dermatol 2022 Feb;21(2):482-500. Epub 2021 Apr 18 doi: 10.1111/jocd.14135. PMID: 33817950
Yang CS, Teeple M, Muglia J, Robinson-Bostom L
Clin Dermatol 2016 May-Jun;34(3):335-43. Epub 2016 Feb 11 doi: 10.1016/j.clindermatol.2016.02.005. PMID: 27265071
Kamada A, Saga K, Jimbow K
J Am Acad Dermatol 2003 Mar;48(3):453-5. doi: 10.1067/mjd.2003.93. PMID: 12637930
Pasricha JS, Nayyar KC
Dermatologica 1973;147(4):271-3. doi: 10.1159/000251880. PMID: 4780778

Clinical prediction guides

Mallat F, Chaaya C, Aoun M, Soutou B, Helou J
J Cutan Med Surg 2023 Jul-Aug;27(4):375-387. Epub 2023 Jun 5 doi: 10.1177/12034754231174852. PMID: 37272371
Yang CS, Teeple M, Muglia J, Robinson-Bostom L
Clin Dermatol 2016 May-Jun;34(3):335-43. Epub 2016 Feb 11 doi: 10.1016/j.clindermatol.2016.02.005. PMID: 27265071
Kassuga LE, Medrado MM, Chevrand NS, Salles Sde A, Vilar EG
An Bras Dermatol 2012 Mar-Apr;87(2):329-31. doi: 10.1590/s0365-05962012000200029. PMID: 22570049
Tetzlaff MT, Evans K, DeHoratius DM, Weiss R, Cotsarelis G, Elenitsas R
Arch Dermatol 2011 May;147(5):573-6. doi: 10.1001/archdermatol.2011.103. PMID: 21576577
Shimizu H
Bull Pharm Res Inst 1966 Jan;60:7-13. PMID: 6012859

Recent systematic reviews

Salloum A, Bouferraa Y, Bazzi N, Bou Zerdan M, Abi Chebl J, Chu T, Bachour J, Benedetto A
J Cosmet Dermatol 2022 Feb;21(2):482-500. Epub 2021 Apr 18 doi: 10.1111/jocd.14135. PMID: 33817950

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...