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Gonococcal urethritis

MedGen UID:
42278
•Concept ID:
C0018078
•
Disease or Syndrome
Synonyms: gc urethritis; Gonococcal Urethritis; gonococcal urethritis; Inflammation of urethra caused by Neisseria gonorrhoeae
SNOMED CT: Gonococcal urethritis (236682002); Inflammation of urethra caused by Neisseria gonorrhoeae (236682002)
 
Monarch Initiative: MONDO:0020971

Definition

Inflammation of the urethra secondary to infection with Neisseria gonorrhoeae; this infection is spread through sexual contact. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGonococcal urethritis

Professional guidelines

PubMed

2021 European guideline on the management of Mycoplasma genitalium infections.
Jensen JS, Cusini M, Gomberg M, Moi H, Wilson J, Unemo M
J Eur Acad Dermatol Venereol 2022 May;36(5):641-650. Epub 2022 Feb 19 doi: 10.1111/jdv.17972. PMID: 35182080
2016 European guideline on the management of non-gonococcal urethritis published.
Moi H, Horner PJ
Euro Surveill 2016 Jun 2;21(22) doi: 10.2807/1560-7917.ES.2016.21.22.30248. PMID: 27277944
Treatment regimens in non-gonococcal urethritis.
Carter N, Horner P
Sex Transm Infect 2015 Jun;91(4):244. doi: 10.1136/sextrans-2014-051837. PMID: 25990780

Recent clinical studies

Etiology

2023 Korean Association of Urogenital Tract Infection and Inflammation guidelines for gonococcal infection.
Yang HJ, Lee HM, Lee SJ, Choi JB, Bae S, Jung JH, Kang TW, Hwang EC
Investig Clin Urol 2024 Jan;65(1):1-8. doi: 10.4111/icu.20230265. PMID: 38197745Free PMC Article
2021 European guideline on the management of Mycoplasma genitalium infections.
Jensen JS, Cusini M, Gomberg M, Moi H, Wilson J, Unemo M
J Eur Acad Dermatol Venereol 2022 May;36(5):641-650. Epub 2022 Feb 19 doi: 10.1111/jdv.17972. PMID: 35182080
Mycoplasma genitalium: A Review.
Gnanadurai R, Fifer H
Microbiology (Reading) 2020 Jan;166(1):21-29. doi: 10.1099/mic.0.000830. PMID: 31329090
Gonococcal urethritis.
Harrison WO
Urol Clin North Am 1984 Feb;11(1):45-53. PMID: 6231755
Prepubertal gonorrhea.
Meek JM, Askari A, Belman AB
J Urol 1979 Oct;122(4):532-4. doi: 10.1016/s0022-5347(17)56495-2. PMID: 480500

Diagnosis

2021 European guideline on the management of Mycoplasma genitalium infections.
Jensen JS, Cusini M, Gomberg M, Moi H, Wilson J, Unemo M
J Eur Acad Dermatol Venereol 2022 May;36(5):641-650. Epub 2022 Feb 19 doi: 10.1111/jdv.17972. PMID: 35182080
Mycoplasma genitalium: A Review.
Gnanadurai R, Fifer H
Microbiology (Reading) 2020 Jan;166(1):21-29. doi: 10.1099/mic.0.000830. PMID: 31329090
Adenovirus-associated paraphimosis.
Pollack A, Varma R
Int J STD AIDS 2019 Jul;30(8):825-827. Epub 2019 May 9 doi: 10.1177/0956462419842448. PMID: 31072279
Non-gonococcal urethritis.
Perkins MJ, Decker CF
Dis Mon 2016 Aug;62(8):274-9. Epub 2016 Apr 20 doi: 10.1016/j.disamonth.2016.03.011. PMID: 27107783
Sexually transmitted diphtheria.
Berger A, Lensing C, Konrad R, Huber I, Hogardt M, Sing A
Sex Transm Infect 2013 Mar;89(2):100-1. Epub 2012 May 23 doi: 10.1136/sextrans-2011-050418. PMID: 22628666

Therapy

2021 European guideline on the management of Mycoplasma genitalium infections.
Jensen JS, Cusini M, Gomberg M, Moi H, Wilson J, Unemo M
J Eur Acad Dermatol Venereol 2022 May;36(5):641-650. Epub 2022 Feb 19 doi: 10.1111/jdv.17972. PMID: 35182080
Mycoplasma genitalium: A Review.
Gnanadurai R, Fifer H
Microbiology (Reading) 2020 Jan;166(1):21-29. doi: 10.1099/mic.0.000830. PMID: 31329090
Adenovirus-associated paraphimosis.
Pollack A, Varma R
Int J STD AIDS 2019 Jul;30(8):825-827. Epub 2019 May 9 doi: 10.1177/0956462419842448. PMID: 31072279
Development potential of rifalazil.
Rothstein DM, Hartman AD, Cynamon MH, Eisenstein BI
Expert Opin Investig Drugs 2003 Feb;12(2):255-71. doi: 10.1517/13543784.12.2.255. PMID: 12556219
Gonococcal tysonitis.
Abdul Gaffoor PM
Postgrad Med J 1986 Sep;62(731):869-70. doi: 10.1136/pgmj.62.731.869. PMID: 3809080Free PMC Article

Prognosis

A case of chronic bacterial prostatitis due to Mycoplasma genitalium.
Rossotti R, Travi G, Bana NB, Orcese C, Puoti M
Sex Transm Infect 2023 Dec;99(8):571-573. Epub 2023 Nov 14 doi: 10.1136/sextrans-2023-055935. PMID: 37963760
2021 European guideline on the management of Mycoplasma genitalium infections.
Jensen JS, Cusini M, Gomberg M, Moi H, Wilson J, Unemo M
J Eur Acad Dermatol Venereol 2022 May;36(5):641-650. Epub 2022 Feb 19 doi: 10.1111/jdv.17972. PMID: 35182080
Periurethral abscess complicating gonococcal urethritis: case report and literature review.
Kenfak-Foguena A, Zarkik Y, Wisard M, Praz V, Darling KE, Jaton-Ogay K, Jichlinski P, Cavassini M
Infection 2010 Dec;38(6):497-500. Epub 2010 Sep 3 doi: 10.1007/s15010-010-0050-z. PMID: 20814714
Gonococcal urethritis.
Harrison WO
Urol Clin North Am 1984 Feb;11(1):45-53. PMID: 6231755
Comparison of erythromycin base and estolate in gonococcal urethritis.
Brown ST, Pedersen HB, Holmes KK
JAMA 1977 Sep 26;238(13):1371-3. PMID: 408522

Clinical prediction guides

Clinical profile and co-infections of urethritis in males.
Bellinato F, Maurelli M, Gisondi P, Lleo Fernandez M, Girolomoni G
Ital J Dermatol Venerol 2021 Dec;156(6):681-685. Epub 2021 Jan 11 doi: 10.23736/S2784-8671.20.06773-5. PMID: 33423450
Male non-gonococcal urethritis: From microbiological etiologies to demographic and clinical features.
Ito S, Hanaoka N, Shimuta K, Seike K, Tsuchiya T, Yasuda M, Yokoi S, Nakano M, Ohnishi M, Deguchi T
Int J Urol 2016 Apr;23(4):325-31. Epub 2016 Feb 4 doi: 10.1111/iju.13044. PMID: 26845624
Treatment of uncomplicated gonococcal urethritis in men with two dosages of ciprofloxacin.
Tegelberg-Stassen MJ, van der Hoek JC, Mooi L, Wagenvoort JH, van Joost T, Michel MF, Stolz E
Eur J Clin Microbiol 1986 Apr;5(2):244-6. doi: 10.1007/BF02013999. PMID: 2941291
Urethritis due to Chlamydia trachomatis.
Vaughan-Jackson JD, Dunlop EM, Darougar S, Treharne JD, Taylor-Robinson D
Br J Vener Dis 1977 Jun;53(3):180-3. doi: 10.1136/sti.53.3.180. PMID: 871894Free PMC Article
The use of trimethoprim-sulfamethoxazole in gonococcal infections.
Austin TW, Holmes KK
Can Med Assoc J 1975 Jun 14;112(13 Spec No):37-9. PMID: 805648Free PMC Article

Recent systematic reviews

Association of mycoplasma with prostate cancer: A systematic review and meta-analysis.
Tantengco OAG, Aquino IMC, de Castro Silva M, Rojo RD, Abad CLR
Cancer Epidemiol 2021 Dec;75:102021. Epub 2021 Sep 10 doi: 10.1016/j.canep.2021.102021. PMID: 34517226
Management of Urethritis: Is It Still the Time for Empirical Antibiotic Treatments?
Bartoletti R, Wagenlehner FME, Bjerklund Johansen TE, Köves B, Cai T, Tandogdu Z, Bonkat G
Eur Urol Focus 2019 Jan;5(1):29-35. Epub 2018 Oct 11 doi: 10.1016/j.euf.2018.10.006. PMID: 30318465
The effectiveness of gentamicin in the treatment of Neisseria gonorrhoeae: a systematic review.
Hathorn E, Dhasmana D, Duley L, Ross JD
Syst Rev 2014 Sep 19;3:104. doi: 10.1186/2046-4053-3-104. PMID: 25239090Free PMC Article
Strategies for partner notification for sexually transmitted infections, including HIV.
Ferreira A, Young T, Mathews C, Zunza M, Low N
Cochrane Database Syst Rev 2013 Oct 3;2013(10):CD002843. doi: 10.1002/14651858.CD002843.pub2. PMID: 24092529Free PMC Article
Improved effectiveness of partner notification for patients with sexually transmitted infections: systematic review.
Trelle S, Shang A, Nartey L, Cassell JA, Low N
BMJ 2007 Feb 17;334(7589):354. doi: 10.1136/bmj.39079.460741.7C. PMID: 17237298Free PMC Article

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