Full Report

Format

Full Report
Summary (Text)
Summary (XML)

Send to:

Choose Destination

File
Clipboard
Collections

Dermatitis

MedGen UID:: 4233
•Concept ID:: C0011603
•: Disease or Syndrome

Synonym:	Dermatitides
SNOMED CT:	Dermatitis (703938007)

Definition

An inflammatory process affecting the skin. Signs include red rash, itching, and blister formation. Representative examples are contact dermatitis, atopic dermatitis, and seborrheic dermatitis. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDermatitis

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Skin disorder
        Dermatitis
        Acanthosis nigricans
        Familial acanthosis nigricans
        Acne vulgaris
        Acne conglobata
        Aggravated Acne
        Acneiform dermatitis
        Epidermal Growth Factor Receptor Inhibitor-Induced Acneiform Lesion
        Acrodermatitis
        Acute generalized exanthematous pustulosis
        Allergic contact dermatitis caused by Arnica
        Atopic eczema
        Dermatitis, atopic
        Dermatitis, atopic, 2
        Dermatitis, atopic, 3
        Dermatitis, atopic, 4
        Dermatitis, atopic, 5
        Dermatitis, atopic, 6
        Dermatitis, atopic, 7
        Dermatitis, atopic, 8
        Dermatitis, atopic, 9
        Late onset atopic dermatitis
        Bullous dermatosis
        Cercarial Dermatitis
        Contact dermatitis
        Allergic contact dermatitis
        Photoallergic dermatitis
        Toxicodendron dermatitis
        Irritant dermatitis
        Diaper rash
        Phototoxic dermatitis
        Occupational dermatitis
        Contact dermatitis due to alkali
        Contact dermatitis due to dichromate
        Dermatitis caused by ingested food
        Dermatitis due to Unspecified Substance Taken Internally
        Dermatitis herpetiformis
        Dermatophytosis
        Dermatophytosis of groin and perianal area
        Dermatophytosis of scalp or beard
        Dermatosis papulosa nigra
        Eczematoid dermatitis
        Dyshidrosis
        Nummular eczema
        Perioral eczema
        Seborrheic dermatitis
        Generalized seborrheic dermatitis
        Stasis dermatitis
        Eruption due to drug
        Drug rash with eosinophilia and systemic symptoms
        Allergy to penicillin
        Anticonvulsant Hypersensitivity Syndrome
        Erythema nodosum
        Hand-foot syndrome
        Hand-foot syndrome in sickle cell anemia
        Nicolau Syndrome
        Serum sickness
        Stevens-Johnson syndrome
        Erythroderma
        Congenital exfoliative erythroderma
        Granulomatous dermatitis
        Herpes simplex dermatitis
        Herpes zoster dermatitis
        Herpes zoster with dermatitis of eyelid
        Hydroa vacciniforme
        Immune Checkpoint Inhibitor-Induced Dermatitis
        Intertrigo
        Tinea cruris
        Lichen planus
        Atrophic lichen planus
        Bullous lichen planus
        Hypertrophic lichen planus
        Oral lichen planus
        Lichen sclerosus et atrophicus
        Vulvar lichen sclerosus
        Neurodermatitis
        Palmoplantar pustulosis
        Perioral dermatitis
        Pityriasis capitis
        Pityriasis rosea
        Porphyria cutanea tarda
        Familial porphyria cutanea tarda
        Hepatoerythropoietic porphyria
        Sporadic porphyria cutanea tarda
        Psoriasiform dermatitis
        Psoriasis
        Psoriatic arthritis
        Psoriasis-related juvenile idiopathic arthritis
        Radiation-Recall Dermatitis
        Spongiotic dermatitis
        Urticaria
        Angioedema
        Hereditary angioneurotic edema
        Chronic idiopathic urticaria
        Chronic urticaria
        Darier sign
        Neutrophilic urticarial dermatosis
        Physical urticaria
        Aquagenic urticaria
        Cold urticaria
        Dermatographic urticaria
        Solar urticaria
        Vibratory urticaria
        Vitiligo
        Progressive vitiligo

Professional guidelines

PubMed

International consensus statement on allergy and rhinology: Allergic rhinitis - 2023.

Wise SK, Damask C, Roland LT, Ebert C, Levy JM, Lin S, Luong A, Rodriguez K, Sedaghat AR, Toskala E, Villwock J, Abdullah B, Akdis C, Alt JA, Ansotegui IJ, Azar A, Baroody F, Benninger MS, Bernstein J, Brook C, Campbell R, Casale T, Chaaban MR, Chew FT, Chambliss J, Cianferoni A, Custovic A, Davis EM, DelGaudio JM, Ellis AK, Flanagan C, Fokkens WJ, Franzese C, Greenhawt M, Gill A, Halderman A, Hohlfeld JM, Incorvaia C, Joe SA, Joshi S, Kuruvilla ME, Kim J, Klein AM, Krouse HJ, Kuan EC, Lang D, Larenas-Linnemann D, Laury AM, Lechner M, Lee SE, Lee VS, Loftus P, Marcus S, Marzouk H, Mattos J, McCoul E, Melen E, Mims JW, Mullol J, Nayak JV, Oppenheimer J, Orlandi RR, Phillips K, Platt M, Ramanathan M Jr, Raymond M, Rhee CS, Reitsma S, Ryan M, Sastre J, Schlosser RJ, Schuman TA, Shaker MS, Sheikh A, Smith KA, Soyka MB, Takashima M, Tang M, Tantilipikorn P, Taw MB, Tversky J, Tyler MA, Veling MC, Wallace D, Wang Y, White A, Zhang L
Int Forum Allergy Rhinol 2023 Apr;13(4):293-859. Epub 2023 Mar 6 doi: 10.1002/alr.23090. PMID: 36878860

Scabies: Epidemiology, Diagnosis, and Treatment.

Sunderkötter C, Wohlrab J, Hamm H
Dtsch Arztebl Int 2021 Oct 15;118(41):695-704. doi: 10.3238/arztebl.m2021.0296. PMID: 34615594 Free PMC Article

Atopic Dermatitis: Diagnosis and Treatment.

Frazier W, Bhardwaj N
Am Fam Physician 2020 May 15;101(10):590-598. PMID: 32412211

See all (2825)

Recent clinical studies

Etiology

Atopic dermatitis endotypes: knowledge for personalized medicine.

Kim J, Ahn K
Curr Opin Allergy Clin Immunol 2022 Jun 1;22(3):153-159. Epub 2022 Feb 11 doi: 10.1097/ACI.0000000000000820. PMID: 35152229

From Emollients to Biologicals: Targeting Atopic Dermatitis.

Salvati L, Cosmi L, Annunziato F
Int J Mol Sci 2021 Sep 26;22(19) doi: 10.3390/ijms221910381. PMID: 34638722 Free PMC Article

Irritant Contact Dermatitis.

Bains SN, Nash P, Fonacier L
Clin Rev Allergy Immunol 2019 Feb;56(1):99-109. doi: 10.1007/s12016-018-8713-0. PMID: 30293200

Patch Testing Pearls.

Uyesugi BA, Sheehan MP
Clin Rev Allergy Immunol 2019 Feb;56(1):110-118. doi: 10.1007/s12016-018-8715-y. PMID: 30269296

Common spongiotic dermatoses.

Gru AA, Salavaggione AL
Semin Diagn Pathol 2017 May;34(3):226-236. Epub 2017 Feb 10 doi: 10.1053/j.semdp.2017.02.002. PMID: 28237387

See all (19114)

Diagnosis

Contact Dermatitis: Classifications and Management.

Li Y, Li L
Clin Rev Allergy Immunol 2021 Dec;61(3):245-281. Epub 2021 Jul 15 doi: 10.1007/s12016-021-08875-0. PMID: 34264448

Mimics of Dermatitis.

Bailiff OA, Mowad CM
Immunol Allergy Clin North Am 2021 Aug;41(3):493-515. doi: 10.1016/j.iac.2021.04.009. PMID: 34225903

Skin allergy.

Zuberbier T, Werfel T
Curr Opin Allergy Clin Immunol 2017 Aug;17(4):262. doi: 10.1097/ACI.0000000000000383. PMID: 28622170

Common spongiotic dermatoses.

Gru AA, Salavaggione AL
Semin Diagn Pathol 2017 May;34(3):226-236. Epub 2017 Feb 10 doi: 10.1053/j.semdp.2017.02.002. PMID: 28237387

Contact dermatitis.

Klaus MV, Wieselthier JS
Am Fam Physician 1993 Sep 15;48(4):629-32. PMID: 8379492

See all (23432)

Therapy

Systemic treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials.

Chu AWL, Wong MM, Rayner DG, Guyatt GH, Díaz Martinez JP, Ceccacci R, Zhao IX, McMullen E, Srivastava A, Wang J, Wen A, Wang FC, Brignardello-Petersen R, Izcovich A, Oykhman P, Wheeler KE, Wang J, Spergel JM, Singh JA, Silverberg JI, Ong PY, O'Brien M, Martin SA, Lio PA, Lind ML, LeBovidge J, Kim E, Huynh J, Greenhawt M, Gardner DD, Frazier WT, Ellison K, Chen L, Capozza K, De Benedetto A, Boguniewicz M, Smith Begolka W, Asiniwasis RN, Schneider LC, Chu DK
J Allergy Clin Immunol 2023 Dec;152(6):1470-1492. Epub 2023 Sep 9 doi: 10.1016/j.jaci.2023.08.029. PMID: 37678577

Efficacy and Safety of Upadacitinib in Patients With Moderate to Severe Atopic Dermatitis: Analysis of Follow-up Data From the Measure Up 1 and Measure Up 2 Randomized Clinical Trials.

Simpson EL, Papp KA, Blauvelt A, Chu CY, Hong HC, Katoh N, Calimlim BM, Thyssen JP, Chiou AS, Bissonnette R, Stein Gold LF, Wegzyn C, Hu X, Liu M, Liu J, Tenorio AR, Chu AD, Guttman-Yassky E
JAMA Dermatol 2022 Apr 1;158(4):404-413. doi: 10.1001/jamadermatol.2022.0029. PMID: 35262646 Free PMC Article

Topical finasteride for male and female pattern hair loss: Is it a safe and effective alternative?

Gupta AK, Talukder M
J Cosmet Dermatol 2022 May;21(5):1841-1848. Epub 2022 Mar 14 doi: 10.1111/jocd.14895. PMID: 35238144

Role of nutritional supplements in selected dermatological disorders: A review.

Sardana K, Sachdeva S
J Cosmet Dermatol 2022 Jan;21(1):85-98. Epub 2021 Sep 26 doi: 10.1111/jocd.14436. PMID: 34564936

Systematic review of treatments for atopic eczema.

Hoare C, Li Wan Po A, Williams H
Health Technol Assess 2000;4(37):1-191. PMID: 11134919 Free PMC Article

See all (33698)

Prognosis

Global epidemiology of atopic dermatitis: a comprehensive systematic analysis and modelling study.

Tian J, Zhang D, Yang Y, Huang Y, Wang L, Yao X, Lu Q
Br J Dermatol 2023 Dec 20;190(1):55-61. doi: 10.1093/bjd/ljad339. PMID: 37705227

Increased risk of osteoarthritis in patients with atopic disease.

Baker MC, Sheth K, Lu R, Lu D, von Kaeppler EP, Bhat A, Felson DT, Robinson WH
Ann Rheum Dis 2023 Jun;82(6):866-872. Epub 2023 Mar 27 doi: 10.1136/ard-2022-223640. PMID: 36987654 Free PMC Article

Erythroderma (exfoliative dermatitis). Part 1: underlying causes, clinical presentation and pathogenesis.

Tso S, Satchwell F, Moiz H, Hari T, Dhariwal S, Barlow R, Forbat E, Randeva H, Tan YT, Ilchyshyn A, Kwok MM, Barber TM, Thind C, Tso ACY
Clin Exp Dermatol 2021 Aug;46(6):1001-1010. Epub 2021 May 1 doi: 10.1111/ced.14625. PMID: 33639006

Atopic dermatitis.

Mounsey SJ, Agius E
Br J Hosp Med (Lond) 2017 Dec 2;78(12):C183-C187. doi: 10.12968/hmed.2017.78.12.C183. PMID: 29240493

Diagnosis and management of contact dermatitis.

Usatine RP, Riojas M
Am Fam Physician 2010 Aug 1;82(3):249-55. PMID: 20672788

See all (7744)

Clinical prediction guides

Counting the Burden: Atopic Dermatitis and Health-related Quality of Life.

Ali F, Vyas J, Finlay AY
Acta Derm Venereol 2020 Jun 9;100(12):adv00161. doi: 10.2340/00015555-3511. PMID: 32412644 Free PMC Article

The Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD): The development and reliability testing of a novel clinical outcome measurement instrument for the severity of atopic dermatitis.

Simpson E, Bissonnette R, Eichenfield LF, Guttman-Yassky E, King B, Silverberg JI, Beck LA, Bieber T, Reich K, Kabashima K, Seyger M, Siegfried E, Stingl G, Feldman SR, Menter A, van de Kerkhof P, Yosipovitch G, Paul C, Martel P, Dubost-Brama A, Armstrong J, Chavda R, Frey S, Joubert Y, Milutinovic M, Parneix A, Teixeira HD, Lin CY, Sun L, Klekotka P, Nickoloff B, Dutronc Y, Mallbris L, Janes JM, DeLozier AM, Nunes FP, Paller AS
J Am Acad Dermatol 2020 Sep;83(3):839-846. Epub 2020 Apr 25 doi: 10.1016/j.jaad.2020.04.104. PMID: 32344071

European S2k Guideline on Chronic Pruritus.

Weisshaar E, Szepietowski JC, Dalgard FJ, Garcovich S, Gieler U, Giménez-Arnau AM, Lambert J, Leslie T, Mettang T, Misery L, Şavk E, Streit M, Tschachler E, Wallengren J, Ständer S
Acta Derm Venereol 2019 Apr 1;99(5):469-506. doi: 10.2340/00015555-3164. PMID: 30931482

The grenz zone.

Abbas O, Mahalingam M
Am J Dermatopathol 2013 Feb;35(1):83-91. doi: 10.1097/DAD.0b013e31824feb4e. PMID: 23348142

Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis.

Dermatology 1993;186(1):23-31. doi: 10.1159/000247298. PMID: 8435513

See all (12143)

Recent systematic reviews

Systemic Immunomodulatory Treatments for Atopic Dermatitis: Update of a Living Systematic Review and Network Meta-analysis.

Drucker AM, Morra DE, Prieto-Merino D, Ellis AG, Yiu ZZN, Rochwerg B, Di Giorgio S, Arents BWM, Burton T, Spuls PI, Schmitt J, Flohr C
JAMA Dermatol 2022 May 1;158(5):523-532. doi: 10.1001/jamadermatol.2022.0455. PMID: 35293977 Free PMC Article

Comparative efficacy and safety of systemic therapies used in moderate-to-severe atopic dermatitis: a systematic literature review and network meta-analysis.

Silverberg JI, Thyssen JP, Fahrbach K, Mickle K, Cappelleri JC, Romero W, Cameron MC, Myers DE, Clibborn C, DiBonaventura M
J Eur Acad Dermatol Venereol 2021 Sep;35(9):1797-1810. Epub 2021 Jun 12 doi: 10.1111/jdv.17351. PMID: 33991374 Free PMC Article

Perioral dermatitis: Diagnosis, proposed etiologies, and management.

Searle T, Ali FR, Al-Niaimi F
J Cosmet Dermatol 2021 Dec;20(12):3839-3848. Epub 2021 Mar 16 doi: 10.1111/jocd.14060. PMID: 33751778

Prevalence and Incidence of Atopic Dermatitis: A Systematic Review.

Bylund S, Kobyletzki LB, Svalstedt M, Svensson Å
Acta Derm Venereol 2020 Jun 9;100(12):adv00160. doi: 10.2340/00015555-3510. PMID: 32412646 Free PMC Article

Seborrhoeic dermatitis of the scalp.

Naldi L, Diphoorn J
BMJ Clin Evid 2015 May 27;2015 PMID: 26016669 Free PMC Article

See all (858)

MedGen

National Center for Biotechnology Information