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Seasonal allergy

MedGen UID:
42335
•Concept ID:
C0018621
•
Disease or Syndrome
Synonym: Seasonal allergic rhinitis
SNOMED CT: Seasonal allergy (444316004); Allergic rhinitis caused by pollens (21719001); Allergic rhinitis caused by pollen (21719001); Pollinosis (21719001); Allergy to pollen (300910009); Hay fever (21719001); Hayfever (21719001); Spasmodic rhinorrhea (367498001); Seasonal allergic rhinitis (367498001)
 
HPO: HP:0012395
Monarch Initiative: MONDO:0005324

Definition

An allergy experienced at a particular time of year when trees or grasses pollinate and elicit an allergic reaction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSeasonal allergy

Professional guidelines

PubMed

Targeted Delivery of Montelukast for the Treatment of Alzheimer's Disease.
Datusalia AK, Singh G, Yadav N, Gaun S, Manik M, Singh RK
CNS Neurol Disord Drug Targets 2022;21(10):913-925. doi: 10.2174/1871527320666210902163756. PMID: 34477536
Which is more effective for as-needed treatment of seasonal allergy symptoms: intranasal corticosteroids or oral antihistamines?
Frantz J
J Fam Pract 2002 Mar;51(3):281. PMID: 11978243

Recent clinical studies

Etiology

Pearls and pitfalls of over-the-counter nasal sprays for seasonal allergy.
Hong E, Lewis P, Sheridan D
Nursing 2024 Oct 1;54(10):44-47. Epub 2024 Sep 20 doi: 10.1097/NSG.0000000000000059. PMID: 39302751
Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation.
Kato M, Miyamoto M, Takayanagi F, Ando Y, Fujita Y, Nakayama M, Yoshihara S
J Immunol Res 2023;2023:4075264. Epub 2023 Mar 9 doi: 10.1155/2023/4075264. PMID: 36937005Free PMC Article
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Allergen immunotherapy for allergic respiratory diseases.
Cappella A, Durham SR
Hum Vaccin Immunother 2012 Oct;8(10):1499-512. Epub 2012 Oct 1 doi: 10.4161/hv.21629. PMID: 23095870Free PMC Article
Seasonal allergy and seasonal decrements in athletic performance.
Komarow HD, Postolache TT
Clin Sports Med 2005 Apr;24(2):e35-50, xiii. doi: 10.1016/j.csm.2004.12.006. PMID: 15892916Free PMC Article

Diagnosis

Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation.
Kato M, Miyamoto M, Takayanagi F, Ando Y, Fujita Y, Nakayama M, Yoshihara S
J Immunol Res 2023;2023:4075264. Epub 2023 Mar 9 doi: 10.1155/2023/4075264. PMID: 36937005Free PMC Article
Diagnosed Allergic Conditions in Children Aged 0-17 Years: United States, 2021.
Zablotsky B, Black LI, Akinbami LJ
NCHS Data Brief 2023 Jan;(459):1-8. PMID: 36700870
Ocular disorders associated with PCSK9 inhibitors: A pharmacovigilance disproportionality analysis.
Zhao X, Wu J, Zhu S
Br J Clin Pharmacol 2023 Feb;89(2):458-469. Epub 2022 Aug 26 doi: 10.1111/bcp.15494. PMID: 35973681
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Seasonal allergy and seasonal decrements in athletic performance.
Komarow HD, Postolache TT
Clin Sports Med 2005 Apr;24(2):e35-50, xiii. doi: 10.1016/j.csm.2004.12.006. PMID: 15892916Free PMC Article

Therapy

Tezepelumab reduces exacerbations across all seasons in patients with severe, uncontrolled asthma (NAVIGATOR).
Pavord ID, Hoyte FCL, Lindsley AW, Ambrose CS, Spahn JD, Roseti SL, Cook B, Griffiths JM, Hellqvist Å, Martin N, Llanos JP, Martin N, Colice G, Corren J
Ann Allergy Asthma Immunol 2023 Nov;131(5):587-597.e3. Epub 2023 Aug 23 doi: 10.1016/j.anai.2023.08.015. PMID: 37619779
Targeted Delivery of Montelukast for the Treatment of Alzheimer's Disease.
Datusalia AK, Singh G, Yadav N, Gaun S, Manik M, Singh RK
CNS Neurol Disord Drug Targets 2022;21(10):913-925. doi: 10.2174/1871527320666210902163756. PMID: 34477536
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Seasonal allergy and seasonal decrements in athletic performance.
Komarow HD, Postolache TT
Clin Sports Med 2005 Apr;24(2):e35-50, xiii. doi: 10.1016/j.csm.2004.12.006. PMID: 15892916Free PMC Article
Allergen biodistribution in humans.
Bagnasco M, Morbelli S, Altrinetti V, Falagiani P, Mariani G, Passalacqua G
Chem Immunol Allergy 2003;82:33-43. doi: 10.1159/000071538. PMID: 12947990

Prognosis

MiR-328-3p promotes TGF-β1-induced proliferation, migration, and inflammation of airway smooth muscle cells by regulating the PTEN/Akt pathway.
Gao J, Wu XL
Allergol Immunopathol (Madr) 2023;51(2):151-159. Epub 2023 Mar 1 doi: 10.15586/aei.v51i2.767. PMID: 36916101
Exposure to Respirable Particulate Matter and Its Association with Respiratory Outcomes in Beauty Salon Personnel.
Vinnikov D, Romanova Z, Raushanova A, Beisbekova A, Vitale E, Bimuratova G, Rapisarda V
Int J Environ Res Public Health 2023 Jan 30;20(3) doi: 10.3390/ijerph20032429. PMID: 36767795Free PMC Article
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Could seasonal allergy be a risk factor for acute rhinosinusitis in children?
Leo G, Incorvaia C, Cazzavillan A, Consonni D, Zuccotti GV
J Laryngol Otol 2018 Feb;132(2):150-153. Epub 2018 Jan 18 doi: 10.1017/S0022215118000038. PMID: 29343309
Allergen biodistribution in humans.
Bagnasco M, Morbelli S, Altrinetti V, Falagiani P, Mariani G, Passalacqua G
Chem Immunol Allergy 2003;82:33-43. doi: 10.1159/000071538. PMID: 12947990

Clinical prediction guides

Allergen immunotherapy effectively reduces the risk of exacerbations and lower respiratory tract infections in both seasonal and perennial allergic asthma: a nationwide epidemiological study.
Woehlk C, Von Bülow A, Ghanizada M, Søndergaard MB, Hansen S, Porsbjerg C
Eur Respir J 2022 Nov;60(5) Epub 2022 Nov 17 doi: 10.1183/13993003.00446-2022. PMID: 35618279
Determining the minimal important differences in the RQLQ score with grass and tree allergy immunotherapy versus placebo in adults with moderate-to-severe allergy.
Blaiss MS, Gronskyte Juhl R, Siew LQC, Hammerby E, Devillier P
Allergy 2022 Jun;77(6):1843-1851. Epub 2022 Jan 22 doi: 10.1111/all.15207. PMID: 34986506Free PMC Article
Sensitization against Fungi in Patients with Airway Allergies over 20 Years in Germany.
Forkel S, Beutner C, Schröder SS, Bader O, Gupta S, Fuchs T, Schön MP, Geier J, Buhl T
Int Arch Allergy Immunol 2021;182(6):515-523. Epub 2021 Mar 29 doi: 10.1159/000512230. PMID: 33780961Free PMC Article
Conjunctival provocation tests: prediction of seasonal allergy.
Schröder J, Mösges R
Curr Opin Allergy Clin Immunol 2018 Oct;18(5):393-397. doi: 10.1097/ACI.0000000000000470. PMID: 30020256
Communicating efficacy information based on composite scores in direct-to-consumer prescription drug advertising.
Williams PA, O'Donoghue AC, Sullivan HW, Willoughby JF, Squire C, Parvanta S, Betts KR
Patient Educ Couns 2016 Apr;99(4):583-590. Epub 2015 Nov 5 doi: 10.1016/j.pec.2015.10.019. PMID: 26589655Free PMC Article

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