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Childhood Malignant Liver Neoplasm

MedGen UID:
424855
Concept ID:
C2945767
Neoplastic Process
Synonyms: Childhood Cancer of Liver; Childhood Cancer of the Liver; Childhood Liver Cancer; Childhood Malignant Liver Tumor; Pediatric Cancer of Liver; Pediatric Cancer of the Liver; Pediatric Liver Cancer; Pediatric Malignant Liver Neoplasm

Definition

A malignant neoplasm that affects the liver and occurs during childhood. [from NCI]

Professional guidelines

PubMed

Stinco M, Rubino C, Trapani S, Indolfi G
World J Gastroenterol 2021 Sep 28;27(36):6053-6063. doi: 10.3748/wjg.v27.i36.6053. PMID: 34629819Free PMC Article
Yu W, Wu N, Li L, Wang J, OuYang H, Shen H
Endocr Pract 2020 Feb;26(2):207-217. Epub 2019 Oct 25 doi: 10.4158/EP-2019-0221. PMID: 31652102
Towbin AJ, Meyers RL, Woodley H, Miyazaki O, Weldon CB, Morland B, Hiyama E, Czauderna P, Roebuck DJ, Tiao GM
Pediatr Radiol 2018 Apr;48(4):536-554. Epub 2018 Feb 9 doi: 10.1007/s00247-018-4078-z. PMID: 29427028

Recent clinical studies

Etiology

Huang H, Wu L, Lu L, Zhang Z, Qiu B, Mo J, Luo Y, Xi Z, Feng M, Wan P, Zhu J, Yu D, Wu W, Tan K, Liu J, Sheng Q, Xu T, Huang J, Lv Z, Tang Y, Xia Q
Hepatology 2023 Jun 1;77(6):1911-1928. Epub 2023 Mar 29 doi: 10.1002/hep.32775. PMID: 36059151
Bendor CD, Bardugo A, Pinhas-Hamiel O, Afek A, Twig G
Cardiovasc Diabetol 2020 Jun 13;19(1):79. doi: 10.1186/s12933-020-01052-1. PMID: 32534575Free PMC Article
Ranganathan S, Lopez-Terrada D, Alaggio R
Pediatr Dev Pathol 2020 Mar-Apr;23(2):79-95. Epub 2019 Sep 25 doi: 10.1177/1093526619875228. PMID: 31554479
Towbin AJ, Meyers RL, Woodley H, Miyazaki O, Weldon CB, Morland B, Hiyama E, Czauderna P, Roebuck DJ, Tiao GM
Pediatr Radiol 2018 Apr;48(4):536-554. Epub 2018 Feb 9 doi: 10.1007/s00247-018-4078-z. PMID: 29427028
Alicandro G, Tavani A, La Vecchia C
Eur J Cancer Prev 2017 Sep;26(5):424-432. doi: 10.1097/CEJ.0000000000000341. PMID: 28288025

Diagnosis

Stinco M, Rubino C, Trapani S, Indolfi G
World J Gastroenterol 2021 Sep 28;27(36):6053-6063. doi: 10.3748/wjg.v27.i36.6053. PMID: 34629819Free PMC Article
Kim E, Viatour P
Exp Mol Med 2020 Dec;52(12):1898-1907. Epub 2020 Dec 2 doi: 10.1038/s12276-020-00527-1. PMID: 33268834Free PMC Article
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Ranganathan S, Lopez-Terrada D, Alaggio R
Pediatr Dev Pathol 2020 Mar-Apr;23(2):79-95. Epub 2019 Sep 25 doi: 10.1177/1093526619875228. PMID: 31554479
Indolfi G, Easterbrook P, Dusheiko G, Siberry G, Chang MH, Thorne C, Bulterys M, Chan PL, El-Sayed MH, Giaquinto C, Jonas MM, Meyers T, Walsh N, Wirth S, Penazzato M
Lancet Gastroenterol Hepatol 2019 Jun;4(6):466-476. Epub 2019 Apr 11 doi: 10.1016/S2468-1253(19)30042-1. PMID: 30982722

Therapy

Huang H, Wu L, Lu L, Zhang Z, Qiu B, Mo J, Luo Y, Xi Z, Feng M, Wan P, Zhu J, Yu D, Wu W, Tan K, Liu J, Sheng Q, Xu T, Huang J, Lv Z, Tang Y, Xia Q
Hepatology 2023 Jun 1;77(6):1911-1928. Epub 2023 Mar 29 doi: 10.1002/hep.32775. PMID: 36059151
Stinco M, Rubino C, Trapani S, Indolfi G
World J Gastroenterol 2021 Sep 28;27(36):6053-6063. doi: 10.3748/wjg.v27.i36.6053. PMID: 34629819Free PMC Article
Indolfi G, Easterbrook P, Dusheiko G, Siberry G, Chang MH, Thorne C, Bulterys M, Chan PL, El-Sayed MH, Giaquinto C, Jonas MM, Meyers T, Walsh N, Wirth S, Penazzato M
Lancet Gastroenterol Hepatol 2019 Jun;4(6):466-476. Epub 2019 Apr 11 doi: 10.1016/S2468-1253(19)30042-1. PMID: 30982722
Towbin AJ, Meyers RL, Woodley H, Miyazaki O, Weldon CB, Morland B, Hiyama E, Czauderna P, Roebuck DJ, Tiao GM
Pediatr Radiol 2018 Apr;48(4):536-554. Epub 2018 Feb 9 doi: 10.1007/s00247-018-4078-z. PMID: 29427028
Alicandro G, Tavani A, La Vecchia C
Eur J Cancer Prev 2017 Sep;26(5):424-432. doi: 10.1097/CEJ.0000000000000341. PMID: 28288025

Prognosis

Clavería-Cabello A, Herranz JM, Latasa MU, Arechederra M, Uriarte I, Pineda-Lucena A, Prosper F, Berraondo P, Alonso C, Sangro B, García Marin JJ, Martinez-Chantar ML, Ciordia S, Corrales FJ, Francalanci P, Alaggio R, Zucman-Rossi J, Indersie E, Cairo S, Domingo-Sàbat M, Zanatto L, Sancho-Bru P, Armengol C, Berasain C, Fernandez-Barrena MG, Avila MA
J Hepatol 2023 Oct;79(4):989-1005. Epub 2023 Jun 10 doi: 10.1016/j.jhep.2023.05.031. PMID: 37302584
Kim E, Viatour P
Exp Mol Med 2020 Dec;52(12):1898-1907. Epub 2020 Dec 2 doi: 10.1038/s12276-020-00527-1. PMID: 33268834Free PMC Article
Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Bendor CD, Bardugo A, Pinhas-Hamiel O, Afek A, Twig G
Cardiovasc Diabetol 2020 Jun 13;19(1):79. doi: 10.1186/s12933-020-01052-1. PMID: 32534575Free PMC Article
Ranganathan S, Lopez-Terrada D, Alaggio R
Pediatr Dev Pathol 2020 Mar-Apr;23(2):79-95. Epub 2019 Sep 25 doi: 10.1177/1093526619875228. PMID: 31554479

Clinical prediction guides

Li N, Zhu Q, Tian Y, Ahn KJ, Wang X, Cramer Z, Jou J, Folkert IW, Yu P, Adams-Tzivelekidis S, Sehgal P, Mahmoud NN, Aarons CB, Roses RE, Thomas-Tikhonenko A, Furth EE, Stanger BZ, Rustgi A, Haldar M, Katona BW, Tan K, Lengner CJ
Nat Commun 2023 Nov 30;14(1):7915. doi: 10.1038/s41467-023-43746-6. PMID: 38036590Free PMC Article
Murthy AB, Palaniappan V, Karthikeyan K, Anbarasan V
Int J Dermatol 2023 Oct;62(10):1218-1227. Epub 2023 Aug 27 doi: 10.1111/ijd.16817. PMID: 37634201
Clavería-Cabello A, Herranz JM, Latasa MU, Arechederra M, Uriarte I, Pineda-Lucena A, Prosper F, Berraondo P, Alonso C, Sangro B, García Marin JJ, Martinez-Chantar ML, Ciordia S, Corrales FJ, Francalanci P, Alaggio R, Zucman-Rossi J, Indersie E, Cairo S, Domingo-Sàbat M, Zanatto L, Sancho-Bru P, Armengol C, Berasain C, Fernandez-Barrena MG, Avila MA
J Hepatol 2023 Oct;79(4):989-1005. Epub 2023 Jun 10 doi: 10.1016/j.jhep.2023.05.031. PMID: 37302584
Younossi ZM, Marchesini G, Pinto-Cortez H, Petta S
Transplantation 2019 Jan;103(1):22-27. doi: 10.1097/TP.0000000000002484. PMID: 30335697
Meyers RL, Maibach R, Hiyama E, Häberle B, Krailo M, Rangaswami A, Aronson DC, Malogolowkin MH, Perilongo G, von Schweinitz D, Ansari M, Lopez-Terrada D, Tanaka Y, Alaggio R, Leuschner I, Hishiki T, Schmid I, Watanabe K, Yoshimura K, Feng Y, Rinaldi E, Saraceno D, Derosa M, Czauderna P
Lancet Oncol 2017 Jan;18(1):122-131. Epub 2016 Nov 22 doi: 10.1016/S1470-2045(16)30598-8. PMID: 27884679Free PMC Article

Recent systematic reviews

Wang YT, Hu KR, Zhao J, Ai FL, Shi YL, Wang XW, Yang WY, Wang JX, Ai LM, Wan X
Biomed Environ Sci 2023 Jan 20;36(1):24-37. doi: 10.3967/bes2023.003. PMID: 36650679
Bendor CD, Bardugo A, Pinhas-Hamiel O, Afek A, Twig G
Cardiovasc Diabetol 2020 Jun 13;19(1):79. doi: 10.1186/s12933-020-01052-1. PMID: 32534575Free PMC Article
Dasgupta P, Henshaw C, Youlden DR, Aitken JF, Sullivan A, Irving H, Baade PD
Paediatr Perinat Epidemiol 2020 Sep;34(5):609-617. Epub 2020 Apr 26 doi: 10.1111/ppe.12671. PMID: 32337759
Yu W, Wu N, Li L, Wang J, OuYang H, Shen H
Endocr Pract 2020 Feb;26(2):207-217. Epub 2019 Oct 25 doi: 10.4158/EP-2019-0221. PMID: 31652102
Mulder RL, van Dalen EC, Van den Hof M, Bresters D, Koot BG, Castellino SM, Loke Y, Leclercq E, Post PN, Caron HN, Postma A, Kremer LC
Cochrane Database Syst Rev 2011 Jul 6;2011(7):CD008205. doi: 10.1002/14651858.CD008205.pub2. PMID: 21735424Free PMC Article

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