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Hidradenitis

MedGen UID:
43115
Concept ID:
C0085160
Disease or Syndrome
Synonyms: Hidradenitides; Hidrosadenitides; Hidrosadenitis; Hydradenitides; Hydradenitis
SNOMED CT: Hidradenitis (69741000)
 
Monarch Initiative: MONDO:0002260

Definition

Inflammation of the apocrine sweat glands, characterized by redness, itching, pain or swelling of the sweat glands, usually in the axillae or groin. [from NCI]

Professional guidelines

PubMed

Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y
J Am Acad Dermatol 2019 Jul;81(1):76-90. Epub 2019 Mar 11 doi: 10.1016/j.jaad.2019.02.067. PMID: 30872156Free PMC Article
Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y
J Am Acad Dermatol 2019 Jul;81(1):91-101. Epub 2019 Mar 11 doi: 10.1016/j.jaad.2019.02.068. PMID: 30872149Free PMC Article
Saunte DML, Jemec GBE
JAMA 2017 Nov 28;318(20):2019-2032. doi: 10.1001/jama.2017.16691. PMID: 29183082

Recent clinical studies

Etiology

Nguyen TV, Damiani G, Orenstein LAV, Hamzavi I, Jemec GB
J Eur Acad Dermatol Venereol 2021 Jan;35(1):50-61. Epub 2020 Jul 16 doi: 10.1111/jdv.16677. PMID: 32460374
Goldburg SR, Strober BE, Payette MJ
J Am Acad Dermatol 2020 May;82(5):1045-1058. Epub 2019 Oct 9 doi: 10.1016/j.jaad.2019.08.090. PMID: 31604104
Goldburg SR, Strober BE, Payette MJ
J Am Acad Dermatol 2020 May;82(5):1061-1082. Epub 2019 Oct 9 doi: 10.1016/j.jaad.2019.08.089. PMID: 31604100
Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y
J Am Acad Dermatol 2019 Jul;81(1):76-90. Epub 2019 Mar 11 doi: 10.1016/j.jaad.2019.02.067. PMID: 30872156Free PMC Article
Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y
J Am Acad Dermatol 2019 Jul;81(1):91-101. Epub 2019 Mar 11 doi: 10.1016/j.jaad.2019.02.068. PMID: 30872149Free PMC Article

Diagnosis

Jenkins T, Isaac J, Edwards A, Okoye GA
Dermatol Clin 2023 Jul;41(3):471-479. Epub 2023 Apr 15 doi: 10.1016/j.det.2023.02.001. PMID: 37236715
Scala E, Cacciapuoti S, Garzorz-Stark N, Megna M, Marasca C, Seiringer P, Volz T, Eyerich K, Fabbrocini G
Cells 2021 Aug 15;10(8) doi: 10.3390/cells10082094. PMID: 34440863Free PMC Article
Goldburg SR, Strober BE, Payette MJ
J Am Acad Dermatol 2020 May;82(5):1045-1058. Epub 2019 Oct 9 doi: 10.1016/j.jaad.2019.08.090. PMID: 31604104
Saunte DML, Jemec GBE
JAMA 2017 Nov 28;318(20):2019-2032. doi: 10.1001/jama.2017.16691. PMID: 29183082
Lee EY, Alhusayen R, Lansang P, Shear N, Yeung J
Can Fam Physician 2017 Feb;63(2):114-120. PMID: 28209676Free PMC Article

Therapy

Kimball AB, Jemec GBE, Alavi A, Reguiai Z, Gottlieb AB, Bechara FG, Paul C, Giamarellos Bourboulis EJ, Villani AP, Schwinn A, Ruëff F, Pillay Ramaya L, Reich A, Lobo I, Sinclair R, Passeron T, Martorell A, Mendes-Bastos P, Kokolakis G, Becherel PA, Wozniak MB, Martinez AL, Wei X, Uhlmann L, Passera A, Keefe D, Martin R, Field C, Chen L, Vandemeulebroecke M, Ravichandran S, Muscianisi E
Lancet 2023 Mar 4;401(10378):747-761. Epub 2023 Feb 3 doi: 10.1016/S0140-6736(23)00022-3. PMID: 36746171
Searle T, Ali FR, Al-Niaimi F
J Dermatolog Treat 2022 Aug;33(5):2455-2458. Epub 2022 Apr 18 doi: 10.1080/09546634.2022.2062282. PMID: 35437093
Scala E, Cacciapuoti S, Garzorz-Stark N, Megna M, Marasca C, Seiringer P, Volz T, Eyerich K, Fabbrocini G
Cells 2021 Aug 15;10(8) doi: 10.3390/cells10082094. PMID: 34440863Free PMC Article
Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y
J Am Acad Dermatol 2019 Jul;81(1):76-90. Epub 2019 Mar 11 doi: 10.1016/j.jaad.2019.02.067. PMID: 30872156Free PMC Article
Lee EY, Alhusayen R, Lansang P, Shear N, Yeung J
Can Fam Physician 2017 Feb;63(2):114-120. PMID: 28209676Free PMC Article

Prognosis

Sun Q, Broadaway KA, Edmiston SN, Fajgenbaum K, Miller-Fleming T, Westerkam LL, Melendez-Gonzalez M, Bui H, Blum FR, Levitt B, Lin L, Hao H, Harris KM, Liu Z, Thomas NE, Cox NJ, Li Y, Mohlke KL, Sayed CJ
JAMA Dermatol 2023 Sep 1;159(9):930-938. doi: 10.1001/jamadermatol.2023.2217. PMID: 37494057Free PMC Article
Johnston LA, Alhusayen R, Bourcier M, Delorme I, George R, O'Brien E, Wong SM, Poelman SM
J Cutan Med Surg 2022 Sep-Oct;26(2_suppl):2S-24S. Epub 2022 Aug 24 doi: 10.1177/12034754221116115. PMID: 36000460
Diotallevi F, Campanati A, Martina E, Radi G, Paolinelli M, Marani A, Molinelli E, Candelora M, Taus M, Galeazzi T, Nicolai A, Offidani A
Nutrients 2022 Jan 29;14(3) doi: 10.3390/nu14030591. PMID: 35276950Free PMC Article
Goldburg SR, Strober BE, Payette MJ
J Am Acad Dermatol 2020 May;82(5):1045-1058. Epub 2019 Oct 9 doi: 10.1016/j.jaad.2019.08.090. PMID: 31604104
Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y
J Am Acad Dermatol 2019 Jul;81(1):91-101. Epub 2019 Mar 11 doi: 10.1016/j.jaad.2019.02.068. PMID: 30872149Free PMC Article

Clinical prediction guides

Snyder CL, Gibson RS, Porter ML, Kimball AB
Immunotherapy 2023 Dec;15(17):1449-1457. Epub 2023 Oct 16 doi: 10.2217/imt-2023-0103. PMID: 37840286
Glatt S, Jemec GBE, Forman S, Sayed C, Schmieder G, Weisman J, Rolleri R, Seegobin S, Baeten D, Ionescu L, Zouboulis CC, Shaw S
JAMA Dermatol 2021 Nov 1;157(11):1279-1288. doi: 10.1001/jamadermatol.2021.2905. PMID: 34406364Free PMC Article
Jfri A, Nassim D, O'Brien E, Gulliver W, Nikolakis G, Zouboulis CC
JAMA Dermatol 2021 Aug 1;157(8):924-931. doi: 10.1001/jamadermatol.2021.1677. PMID: 34037678Free PMC Article
Nguyen TV, Damiani G, Orenstein LAV, Hamzavi I, Jemec GB
J Eur Acad Dermatol Venereol 2021 Jan;35(1):50-61. Epub 2020 Jul 16 doi: 10.1111/jdv.16677. PMID: 32460374
Tchero H, Herlin C, Bekara F, Fluieraru S, Teot L
Indian J Dermatol Venereol Leprol 2019 May-Jun;85(3):248-257. doi: 10.4103/ijdvl.IJDVL_69_18. PMID: 30924446

Recent systematic reviews

Arnold DD, Yalamanoglu A, Boyman O
Front Immunol 2022;13:888392. Epub 2022 Jul 6 doi: 10.3389/fimmu.2022.888392. PMID: 35874710Free PMC Article
Shih T, Lee K, Grogan T, De DR, Shi VY, Hsiao JL
Dermatol Ther 2022 Sep;35(9):e15691. Epub 2022 Jul 18 doi: 10.1111/dth.15691. PMID: 35790062Free PMC Article
Jfri A, Nassim D, O'Brien E, Gulliver W, Nikolakis G, Zouboulis CC
JAMA Dermatol 2021 Aug 1;157(8):924-931. doi: 10.1001/jamadermatol.2021.1677. PMID: 34037678Free PMC Article
Yee BE, Richards P, Sui JY, Marsch AF
Dermatol Ther 2020 Nov;33(6):e14252. Epub 2020 Sep 15 doi: 10.1111/dth.14252. PMID: 32860489
Tchero H, Herlin C, Bekara F, Fluieraru S, Teot L
Indian J Dermatol Venereol Leprol 2019 May-Jun;85(3):248-257. doi: 10.4103/ijdvl.IJDVL_69_18. PMID: 30924446

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