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Yin deficiency

MedGen UID:
43138
•Concept ID:
C0085257
•
Pathologic Function
Synonyms: Deficiency, Yin; Hsu, Yin; Xu, Yin; Yin Deficiencies; Yin Deficiency; Yin Hsu; Yin Xu; Yinxu
SNOMED CT: Yin deficiency (370538004)

Definition

In the YIN-YANG system of philosophy and medicine, an insufficiency of body fluid (called yinxu), manifesting often as irritability, thirst, constipation, etc. (The Pinyin Chinese-English Dictionary, 1979). [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVYin deficiency

Professional guidelines

PubMed

Research progress in the prevention and treatment of insomnia with classical prescriptions.
Shi X, Chen L, Li W, Wang R
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2023 Oct 28;48(10):1494-1505. doi: 10.11817/j.issn.1672-7347.2023.230200. PMID: 38432879Free PMC Article
A real-world data analysis-based study of Chinese medicine treatment patterns after breast cancer surgery.
Hu L, Yang Y, Wang Z, Wen C, Cheng X
Medicine (Baltimore) 2023 Dec 15;102(50):e36642. doi: 10.1097/MD.0000000000036642. PMID: 38115283Free PMC Article
Appraisal of the Quality and Contents of Clinical Practice Guidelines for Hypertension Management in Chinese Medicine: A Systematic Review.
Yuwen Y, Han XJ, Weng WL, Zhao XY, Liu YQ, Li WQ, Liu DS, Wang YP, Lu AP
Chin J Integr Med 2018 Jul;24(7):545-550. Epub 2016 Dec 9 doi: 10.1007/s11655-016-2277-8. PMID: 27933511

Recent clinical studies

Etiology

The Effectiveness of a Traditional Chinese Medicine-Based Mobile Health App for Individuals With Prediabetes: Randomized Controlled Trial.
Chung HW, Tai CJ, Chang P, Su WL, Chien LY
JMIR Mhealth Uhealth 2023 Jun 20;11:e41099. doi: 10.2196/41099. PMID: 37338977Free PMC Article
Visual analysis and evaluation of clinical research on Traditional Chinese medicine compounds in treating insomnia of Yin deficiency syndrome.
Wu Q, Chen X, Gan G, Zhang Q, Yu L, Li C, Zhang Y, Ao M
J Ethnopharmacol 2022 Nov 15;298:115669. Epub 2022 Aug 27 doi: 10.1016/j.jep.2022.115669. PMID: 36031101
Clinical efficacy of Baihe Gujin decoction combined with anti-tuberculosis therapy for pulmonary tuberculosis with Yin-deficiency and Fire-hyperactivity syndrome.
Ge HB, Zhu J
J Int Med Res 2020 May;48(5):300060519875535. doi: 10.1177/0300060519875535. PMID: 32367748Free PMC Article
Gene Expression Profiles of HIV/AIDS Patients with Qi-Yin Deficiency and Dampness-Heat Retention.
Liu S, Chen Y, Xie S, Xu Q, Chen J, Wang C, Wang Z, Ma S, Wu X, Zhang N
J Altern Complement Med 2016 Nov;22(11):865-879. Epub 2016 Oct 19 doi: 10.1089/acm.2015.0350. PMID: 27759429Free PMC Article
The liver in traditional Chinese medicine.
Chen TS, Chen PS
J Gastroenterol Hepatol 1998 Apr;13(4):437-42. doi: 10.1111/j.1440-1746.1998.tb00662.x. PMID: 9641312

Diagnosis

Visual analysis and evaluation of clinical research on Traditional Chinese medicine compounds in treating insomnia of Yin deficiency syndrome.
Wu Q, Chen X, Gan G, Zhang Q, Yu L, Li C, Zhang Y, Ao M
J Ethnopharmacol 2022 Nov 15;298:115669. Epub 2022 Aug 27 doi: 10.1016/j.jep.2022.115669. PMID: 36031101
Analysis of Traditional Chinese Medicine Diagnosis and Treatment Strategies for COVID-19 Based on "The Diagnosis and Treatment Program for Coronavirus Disease-2019" from Chinese Authority.
Zhao ZH, Zhou Y, Li WH, Huang QS, Tang ZH, Li H
Am J Chin Med 2020;48(5):1035-1049. doi: 10.1142/S0192415X20500500. PMID: 32668970
End-to-End syndrome differentiation of Yin deficiency and Yang deficiency in traditional Chinese medicine.
Hu Q, Yu T, Li J, Yu Q, Zhu L, Gu Y
Comput Methods Programs Biomed 2019 Jun;174:9-15. Epub 2018 Oct 16 doi: 10.1016/j.cmpb.2018.10.011. PMID: 30376987
Development and validation of the Yin deficiency scale.
Park YJ, Cho SW, Lee BH, Park YB
J Altern Complement Med 2013 Jan;19(1):50-6. Epub 2012 Sep 5 doi: 10.1089/acm.2011.0677. PMID: 22950657
The liver in traditional Chinese medicine.
Chen TS, Chen PS
J Gastroenterol Hepatol 1998 Apr;13(4):437-42. doi: 10.1111/j.1440-1746.1998.tb00662.x. PMID: 9641312

Therapy

The Effectiveness of a Traditional Chinese Medicine-Based Mobile Health App for Individuals With Prediabetes: Randomized Controlled Trial.
Chung HW, Tai CJ, Chang P, Su WL, Chien LY
JMIR Mhealth Uhealth 2023 Jun 20;11:e41099. doi: 10.2196/41099. PMID: 37338977Free PMC Article
Visual analysis and evaluation of clinical research on Traditional Chinese medicine compounds in treating insomnia of Yin deficiency syndrome.
Wu Q, Chen X, Gan G, Zhang Q, Yu L, Li C, Zhang Y, Ao M
J Ethnopharmacol 2022 Nov 15;298:115669. Epub 2022 Aug 27 doi: 10.1016/j.jep.2022.115669. PMID: 36031101
Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L
J Tradit Chin Med 2020 Aug;40(4):690-702. doi: 10.19852/j.cnki.jtcm.2020.04.019. PMID: 32744037
Clinical efficacy of Baihe Gujin decoction combined with anti-tuberculosis therapy for pulmonary tuberculosis with Yin-deficiency and Fire-hyperactivity syndrome.
Ge HB, Zhu J
J Int Med Res 2020 May;48(5):300060519875535. doi: 10.1177/0300060519875535. PMID: 32367748Free PMC Article
Characteristics of the traditional Liu-Wei-Di-Huang prescription reassessed in modern pharmacology.
Cheng XR, Qi CH, Wang TX, Zhou WX, Zhang YX
Chin J Nat Med 2019 Feb;17(2):103-121. doi: 10.1016/S1875-5364(19)30013-5. PMID: 30797417

Prognosis

Traditional Chinese medicine body constitution predicts new-onset diabetic albuminuria in patients with type 2 diabetes: Taichung diabetic body constitution prospective cohort study.
Lee CH, Tsai CI, Su YC, Lin SY, Lee IT, Li TC
Medicine (Baltimore) 2022 Dec 16;101(50):e32342. doi: 10.1097/MD.0000000000032342. PMID: 36550881Free PMC Article
Study on the differences of gut microbiota composition between phlegm-dampness syndrome and qi-yin deficiency syndrome in patients with metabolic syndrome.
Shang H, Zhang L, Xiao T, Zhang L, Ruan J, Zhang Q, Liu K, Yu Z, Ni Y, Wang B
Front Endocrinol (Lausanne) 2022;13:1063579. Epub 2022 Nov 9 doi: 10.3389/fendo.2022.1063579. PMID: 36440222Free PMC Article
miRNA Expression Profile of Saliva in Subjects of Yang Deficiency Constitution and Yin Deficiency Constitution.
Chen Y, Wu Y, Yao H, Luo H, Lin B, Zhang X, Liang X, Sun R, Zhao S, Li Y, Zheng Y, Li L, Wang Q
Cell Physiol Biochem 2018;49(5):2088-2098. Epub 2018 Sep 24 doi: 10.1159/000493769. PMID: 30248664
Acupuncture for Menopausal Hot Flashes: A Randomized Trial.
Ee C, Xue C, Chondros P, Myers SP, French SD, Teede H, Pirotta M
Ann Intern Med 2016 Feb 2;164(3):146-54. Epub 2016 Jan 19 doi: 10.7326/M15-1380. PMID: 26784863
Fire-heat and Qi deficiency syndromes as predictors of short-term prognosis of acute ischemic stroke.
Cheng SC, Lin CH, Chang YJ, Lee TH, Ryu SJ, Chen CH, Chang HK, Chang CJ, Hu WL, Hung YC
J Altern Complement Med 2013 Aug;19(8):721-8. Epub 2013 Apr 19 doi: 10.1089/acm.2012.0546. PMID: 23600945Free PMC Article

Clinical prediction guides

The Effectiveness of a Traditional Chinese Medicine-Based Mobile Health App for Individuals With Prediabetes: Randomized Controlled Trial.
Chung HW, Tai CJ, Chang P, Su WL, Chien LY
JMIR Mhealth Uhealth 2023 Jun 20;11:e41099. doi: 10.2196/41099. PMID: 37338977Free PMC Article
Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L
J Tradit Chin Med 2020 Aug;40(4):690-702. doi: 10.19852/j.cnki.jtcm.2020.04.019. PMID: 32744037
Clinical efficacy of Baihe Gujin decoction combined with anti-tuberculosis therapy for pulmonary tuberculosis with Yin-deficiency and Fire-hyperactivity syndrome.
Ge HB, Zhu J
J Int Med Res 2020 May;48(5):300060519875535. doi: 10.1177/0300060519875535. PMID: 32367748Free PMC Article
End-to-End syndrome differentiation of Yin deficiency and Yang deficiency in traditional Chinese medicine.
Hu Q, Yu T, Li J, Yu Q, Zhu L, Gu Y
Comput Methods Programs Biomed 2019 Jun;174:9-15. Epub 2018 Oct 16 doi: 10.1016/j.cmpb.2018.10.011. PMID: 30376987
Development and validation of the Yin deficiency scale.
Park YJ, Cho SW, Lee BH, Park YB
J Altern Complement Med 2013 Jan;19(1):50-6. Epub 2012 Sep 5 doi: 10.1089/acm.2011.0677. PMID: 22950657

Recent systematic reviews

Treatment of type 2 diabetes mellitus using the traditional Chinese medicine Jinlida as an add-on medication: A systematic review and meta-analysis of randomized controlled trials.
Zhao X, Liu L, Liu J
Front Endocrinol (Lausanne) 2022;13:1018450. Epub 2022 Oct 17 doi: 10.3389/fendo.2022.1018450. PMID: 36325446Free PMC Article
Correlation between TCM Constitutional Types and Lung Carcinoma in Various Geographical Areas: A Systematic Review and Meta-Analysis.
Yu X, Yan L, Lan Q, Wan L, Xiong J, Zhang L, Nie H, Ding Z
Contrast Media Mol Imaging 2022;2022:5660231. Epub 2022 Aug 17 doi: 10.1155/2022/5660231. PMID: 36072639Free PMC Article
The association between blood lipid and phlegm turbidity syndrome of angina pectoris: a systematic review and meta-analysis.
Kong D, Wang Y, Liu Y, Zhang Z, Liu G, Qi W, Xiao L, Yuan D, Yang G
Complement Ther Med 2014 Aug;22(4):801-13. Epub 2014 May 27 doi: 10.1016/j.ctim.2014.05.008. PMID: 25146084
Tai chi for primary prevention of cardiovascular disease.
Hartley L, Flowers N, Lee MS, Ernst E, Rees K
Cochrane Database Syst Rev 2014 Apr 9;(4):CD010366. doi: 10.1002/14651858.CD010366.pub2. PMID: 24715694
Traditional Chinese medicine syndrome distribution in chronic hepatitis B populations: a systematic review.
Zeng XX, Bian ZX, Wu TX, Fu SF, Ziea E, Woon WT
Am J Chin Med 2011;39(6):1061-74. doi: 10.1142/S0192415X11009408. PMID: 22083981

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