U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Yang deficiency

MedGen UID:
43139
•Concept ID:
C0085258
•
Pathologic Function
Synonyms: Deficiency, Yang; Hsu, Yang; Xu, Yang; Yang Deficiency; Yang Hsu; Yang Xu; Yangxu
SNOMED CT: Yang deficiency (370534002)

Definition

In the YIN-YANG system of philosophy and medicine, a lack of vital energy (called yangxu in Chinese). It manifests itself in various systemic and organic diseases. (The Pinyin Chinese-English Dictionary, 1979) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVYang deficiency

Professional guidelines

PubMed

Diagnostic and Categorization Criteria for Palpitations Below the Heart in Traditional Chinese Medicine: A Delphi Consensus Study.
Song C, Ye X, Fu H, Lin L, Jin Y, Liu F, Zhu W
Altern Ther Health Med 2021 Sep;27(5):68-72. PMID: 33128537
Exploring the mechanism of TCM formulae in the treatment of different types of coronary heart disease by network pharmacology and machining learning.
Yang J, Tian S, Zhao J, Zhang W
Pharmacol Res 2020 Sep;159:105034. Epub 2020 Jun 18 doi: 10.1016/j.phrs.2020.105034. PMID: 32565312
Clinical trials of traditional Chinese medicine in the treatment of diabetic nephropathy--a systematic review based on a subgroup analysis.
Liu X, Liu L, Chen P, Zhou L, Zhang Y, Wu Y, Jiang L, Cheng D, Huang W, Yi D
J Ethnopharmacol 2014 Feb 3;151(2):810-9. Epub 2013 Dec 1 doi: 10.1016/j.jep.2013.11.028. PMID: 24296085

Recent clinical studies

Etiology

Gut Microbiota and Urine Metabonomics Alterations in Constitution after Chinese Medicine and Lifestyle Intervention.
Jing Y, Han S, Chen J, Lai Y, Cheng J, Li F, Xiao Y, Jiang P, Sun X, Luo R, Zhao X, Liu Y
Am J Chin Med 2021;49(5):1165-1193. Epub 2021 Jun 3 doi: 10.1142/S0192415X21500567. PMID: 34107861
Efficacy and safety of Linggui Zhugan decoction in the treatment of chronic heart failure with Yang deficiency: A protocol for systematic review and meta-analysis.
Li Y, Wu H, Zhang B, Xu X, Wang Y, Song Q
Medicine (Baltimore) 2021 May 21;100(20):e26012. doi: 10.1097/MD.0000000000026012. PMID: 34011101Free PMC Article
The characteristics of intestinal flora of IBS-D with different syndromes.
Chao G, Zhang S
Immun Inflamm Dis 2020 Dec;8(4):615-628. Epub 2020 Sep 17 doi: 10.1002/iid3.348. PMID: 32940426Free PMC Article
Exploring the mechanism of TCM formulae in the treatment of different types of coronary heart disease by network pharmacology and machining learning.
Yang J, Tian S, Zhao J, Zhang W
Pharmacol Res 2020 Sep;159:105034. Epub 2020 Jun 18 doi: 10.1016/j.phrs.2020.105034. PMID: 32565312
Chinese herbal medicines for hypothyroidism.
Ke LQ, Hu Y, Yang K, Tong N
Cochrane Database Syst Rev 2015 Feb 12;(2):CD008779. doi: 10.1002/14651858.CD008779.pub2. PMID: 25914906

Diagnosis

Study of Differential Serum Metabolites in Patients with Adenomatous Polyps of Colon and Yang-Deficiency Constitution Based on Ultra-Performance Liquid Chromatography-Mass Spectrometry.
Du WZ, Zhang AH, Ren JL, Lyu K, Tuo LY, Xu W
Chin J Integr Med 2022 May;28(5):403-409. Epub 2019 Nov 29 doi: 10.1007/s11655-019-3181-9. PMID: 31784934
Efficacy and safety of Linggui Zhugan decoction in the treatment of chronic heart failure with Yang deficiency: A protocol for systematic review and meta-analysis.
Li Y, Wu H, Zhang B, Xu X, Wang Y, Song Q
Medicine (Baltimore) 2021 May 21;100(20):e26012. doi: 10.1097/MD.0000000000026012. PMID: 34011101Free PMC Article
End-to-End syndrome differentiation of Yin deficiency and Yang deficiency in traditional Chinese medicine.
Hu Q, Yu T, Li J, Yu Q, Zhu L, Gu Y
Comput Methods Programs Biomed 2019 Jun;174:9-15. Epub 2018 Oct 16 doi: 10.1016/j.cmpb.2018.10.011. PMID: 30376987
Integrative metabolic and microbial profiling on patients with Spleen-yang-deficiency syndrome.
Lin Z, Ye W, Zu X, Xie H, Li H, Li Y, Zhang W
Sci Rep 2018 Apr 26;8(1):6619. doi: 10.1038/s41598-018-24130-7. PMID: 29700349Free PMC Article
Chinese herbal medicines for hypothyroidism.
Ke LQ, Hu Y, Yang K, Tong N
Cochrane Database Syst Rev 2015 Feb 12;(2):CD008779. doi: 10.1002/14651858.CD008779.pub2. PMID: 25914906

Therapy

Gut Microbiota and Urine Metabonomics Alterations in Constitution after Chinese Medicine and Lifestyle Intervention.
Jing Y, Han S, Chen J, Lai Y, Cheng J, Li F, Xiao Y, Jiang P, Sun X, Luo R, Zhao X, Liu Y
Am J Chin Med 2021;49(5):1165-1193. Epub 2021 Jun 3 doi: 10.1142/S0192415X21500567. PMID: 34107861
Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L
J Tradit Chin Med 2020 Aug;40(4):690-702. doi: 10.19852/j.cnki.jtcm.2020.04.019. PMID: 32744037
Exploring the mechanism of TCM formulae in the treatment of different types of coronary heart disease by network pharmacology and machining learning.
Yang J, Tian S, Zhao J, Zhang W
Pharmacol Res 2020 Sep;159:105034. Epub 2020 Jun 18 doi: 10.1016/j.phrs.2020.105034. PMID: 32565312
Chinese herbal medicines for hypothyroidism.
Ke LQ, Hu Y, Yang K, Tong N
Cochrane Database Syst Rev 2015 Feb 12;(2):CD008779. doi: 10.1002/14651858.CD008779.pub2. PMID: 25914906
Yang-tonifying traditional Chinese medicinal plants and their potential phytoandrogenic activity.
Edouard MJ, Miao L, Fan GW, Ojong BB, Zhen H, Zhang J, Gao XM, Zhu Y
Chin J Nat Med 2014 May;12(5):321-34. doi: 10.1016/S1875-5364(14)60040-6. PMID: 24856755

Prognosis

Dose-effect of long-snake-like moxibustion for chronic fatigue syndrome: a randomized controlled trial.
Luo H, Gong R, Zheng R, Tan J, Chen R, Wu J, Ma T
J Transl Med 2023 Jul 3;21(1):430. doi: 10.1186/s12967-023-04250-z. PMID: 37400824Free PMC Article
miRNA Expression Profile of Saliva in Subjects of Yang Deficiency Constitution and Yin Deficiency Constitution.
Chen Y, Wu Y, Yao H, Luo H, Lin B, Zhang X, Liang X, Sun R, Zhao S, Li Y, Zheng Y, Li L, Wang Q
Cell Physiol Biochem 2018;49(5):2088-2098. Epub 2018 Sep 24 doi: 10.1159/000493769. PMID: 30248664
Effects of symptoms and complementary and alternative medicine use on the yang deficiency pattern among breast cancer patients receiving chemotherapy.
Huang SM, Chien LY, Tai CJ, Chen PH, Lien PJ, Tai CJ
Complement Ther Med 2015 Apr;23(2):233-41. Epub 2015 Jan 12 doi: 10.1016/j.ctim.2015.01.004. PMID: 25847561
Features analysis on Traditional Chinese Medicine syndromes in patients with diabetic peripheral neuropathy.
Li M, Su H, Xiang Y, Zhang J, Zhao J, Lin L
J Tradit Chin Med 2013 Oct;33(5):637-41. doi: 10.1016/s0254-6272(14)60034-0. PMID: 24660588
Analysis on traditional Chinese medicine syndrome elements and relevant factors for senile diabetes.
Wei J, Wu R, Zhao D
J Tradit Chin Med 2013 Aug;33(4):473-8. doi: 10.1016/s0254-6272(13)60151-x. PMID: 24187868

Clinical prediction guides

Gut microbiota and differential genes-maintained homeostasis is key to maintaining health of individuals with Yang-deficiency constitution.
Zhang HX, Wang LM, Guo JP, Wang JA, Zhang QQ, Wang YT, Liu X, Zhang LH, Shi LL, Wu HX, Cao X
J Tradit Chin Med 2022 Feb;42(1):96-101. doi: 10.19852/j.cnki.jtcm.20211012.001. PMID: 35294128Free PMC Article
Gut Microbiota and Urine Metabonomics Alterations in Constitution after Chinese Medicine and Lifestyle Intervention.
Jing Y, Han S, Chen J, Lai Y, Cheng J, Li F, Xiao Y, Jiang P, Sun X, Luo R, Zhao X, Liu Y
Am J Chin Med 2021;49(5):1165-1193. Epub 2021 Jun 3 doi: 10.1142/S0192415X21500567. PMID: 34107861
Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L
J Tradit Chin Med 2020 Aug;40(4):690-702. doi: 10.19852/j.cnki.jtcm.2020.04.019. PMID: 32744037
End-to-End syndrome differentiation of Yin deficiency and Yang deficiency in traditional Chinese medicine.
Hu Q, Yu T, Li J, Yu Q, Zhu L, Gu Y
Comput Methods Programs Biomed 2019 Jun;174:9-15. Epub 2018 Oct 16 doi: 10.1016/j.cmpb.2018.10.011. PMID: 30376987
miRNA Expression Profile of Saliva in Subjects of Yang Deficiency Constitution and Yin Deficiency Constitution.
Chen Y, Wu Y, Yao H, Luo H, Lin B, Zhang X, Liang X, Sun R, Zhao S, Li Y, Zheng Y, Li L, Wang Q
Cell Physiol Biochem 2018;49(5):2088-2098. Epub 2018 Sep 24 doi: 10.1159/000493769. PMID: 30248664

Recent systematic reviews

A systematic review of traditional uses, phytochemistry, pharmacology and toxicity of Epimedium koreanum Nakai.
Qian HQ, Wu DC, Li CY, Liu XR, Han XK, Peng Y, Zhang H, Zhao BY, Zhao Y
J Ethnopharmacol 2024 Jan 10;318(Pt B):116957. Epub 2023 Aug 6 doi: 10.1016/j.jep.2023.116957. PMID: 37544344
Correlation between TCM Constitutional Types and Lung Carcinoma in Various Geographical Areas: A Systematic Review and Meta-Analysis.
Yu X, Yan L, Lan Q, Wan L, Xiong J, Zhang L, Nie H, Ding Z
Contrast Media Mol Imaging 2022;2022:5660231. Epub 2022 Aug 17 doi: 10.1155/2022/5660231. PMID: 36072639Free PMC Article
Chinese herbal medicines for hypothyroidism.
Ke LQ, Hu Y, Yang K, Tong N
Cochrane Database Syst Rev 2015 Feb 12;(2):CD008779. doi: 10.1002/14651858.CD008779.pub2. PMID: 25914906
The association between blood lipid and phlegm turbidity syndrome of angina pectoris: a systematic review and meta-analysis.
Kong D, Wang Y, Liu Y, Zhang Z, Liu G, Qi W, Xiao L, Yuan D, Yang G
Complement Ther Med 2014 Aug;22(4):801-13. Epub 2014 May 27 doi: 10.1016/j.ctim.2014.05.008. PMID: 25146084
Traditional Chinese medicine syndrome distribution in chronic hepatitis B populations: a systematic review.
Zeng XX, Bian ZX, Wu TX, Fu SF, Ziea E, Woon WT
Am J Chin Med 2011;39(6):1061-74. doi: 10.1142/S0192415X11009408. PMID: 22083981

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...