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Obstructive jaundice

MedGen UID:
43988
Concept ID:
C0022354
Disease or Syndrome
Synonyms: Cholestatic Jaundice; Jaundice, Cholestatic; Jaundice, Mechanical; Jaundice, Obstructive; Mechanical Jaundice; Obstructive Jaundice
SNOMED CT: Cholestatic jaundice syndrome (44018007); Cholestatic jaundice (44018007); Obstructive hyperbilirubinemia (59848001); Obstructive jaundice (59848001)
 
Monarch Initiative: MONDO:0006874

Definition

A finding indicating increased bilirubin levels in the blood and urine, due to intrahepatic or extrahepatic obstruction of the biliary system. [from NCI]

Professional guidelines

PubMed

Guardado NV, Llorente K, Blondeau B
Surg Oncol Clin N Am 2021 Jul;30(3):491-503. doi: 10.1016/j.soc.2021.03.001. PMID: 34053664
Löhr JM, Beuers U, Vujasinovic M, Alvaro D, Frøkjær JB, Buttgereit F, Capurso G, Culver EL, de-Madaria E, Della-Torre E, Detlefsen S, Dominguez-Muñoz E, Czubkowski P, Ewald N, Frulloni L, Gubergrits N, Duman DG, Hackert T, Iglesias-Garcia J, Kartalis N, Laghi A, Lammert F, Lindgren F, Okhlobystin A, Oracz G, Parniczky A, Mucelli RMP, Rebours V, Rosendahl J, Schleinitz N, Schneider A, van Bommel EF, Verbeke CS, Vullierme MP, Witt H; UEG guideline working group
United European Gastroenterol J 2020 Jul;8(6):637-666. Epub 2020 Jun 18 doi: 10.1177/2050640620934911. PMID: 32552502Free PMC Article
Madhani K, Farrell JJ
Gastrointest Endosc Clin N Am 2018 Oct;28(4):493-519. Epub 2018 Aug 1 doi: 10.1016/j.giec.2018.05.002. PMID: 30241640

Recent clinical studies

Etiology

Alatise OI, Owojuyigbe AM, Omisore AD, Ndububa DA, Aburime E, Dua KS, Asombang AW
Niger Postgrad Med J 2020 Oct-Dec;27(4):302-310. doi: 10.4103/npmj.npmj_242_20. PMID: 33154282
Pavlidis ET, Pavlidis TE
Hepatobiliary Pancreat Dis Int 2018 Feb;17(1):17-21. Epub 2018 Jan 31 doi: 10.1016/j.hbpd.2018.01.008. PMID: 29428098
Modha K
Tech Vasc Interv Radiol 2015 Dec;18(4):197-200. Epub 2015 Jul 16 doi: 10.1053/j.tvir.2015.07.002. PMID: 26615159
Wani BN, Jajoo SN
Trop Gastroenterol 2009 Oct-Dec;30(4):195-200. PMID: 20426278
BIRCH JR, SHEA J, CURRIE DJ
Can Med Assoc J 1964 Jun 27;90(26):1442-9. PMID: 14158553Free PMC Article

Diagnosis

Modha K
Tech Vasc Interv Radiol 2015 Dec;18(4):197-200. Epub 2015 Jul 16 doi: 10.1053/j.tvir.2015.07.002. PMID: 26615159
Wani BN, Jajoo SN
Trop Gastroenterol 2009 Oct-Dec;30(4):195-200. PMID: 20426278
Qin LX, Tang ZY
World J Gastroenterol 2003 Mar;9(3):385-91. doi: 10.3748/wjg.v9.i3.385. PMID: 12632482Free PMC Article
Bower TC, Nagorney DM
HPB Surg 1988 Sep;1(1):67-74; discussion 75-6. doi: 10.1155/1988/54294. PMID: 3153777Free PMC Article
BIRCH JR, SHEA J, CURRIE DJ
Can Med Assoc J 1964 Jun 27;90(26):1442-9. PMID: 14158553Free PMC Article

Therapy

Teoh AYB, Napoleon B, Kunda R, Arcidiacono PG, Kongkam P, Larghi A, Van der Merwe S, Jacques J, Legros R, Thawee RE, Saxena P, Aerts M, Archibugi L, Chan SM, Fumex F, Kaffes AJ, Ma MTW, Messaoudi N, Rizzatti G, Ng KKC, Ng EKW, Chiu PWY
Gastroenterology 2023 Aug;165(2):473-482.e2. Epub 2023 Apr 28 doi: 10.1053/j.gastro.2023.04.016. PMID: 37121331
Pavlidis ET, Pavlidis TE
Hepatobiliary Pancreat Dis Int 2018 Feb;17(1):17-21. Epub 2018 Jan 31 doi: 10.1016/j.hbpd.2018.01.008. PMID: 29428098
Ogura T, Higuchi K
World J Gastroenterol 2015 Jan 28;21(4):1049-52. doi: 10.3748/wjg.v21.i4.1049. PMID: 25632176Free PMC Article
Minami Y, Kudo M
Dig Dis 2012;30(6):592-7. Epub 2012 Dec 13 doi: 10.1159/000343087. PMID: 23258100
Adam A
Cardiovasc Intervent Radiol 1994 May-Jun;17(3):127-32. doi: 10.1007/BF00195504. PMID: 8087827

Prognosis

Shen WJ, Chen G, Wang M, Zheng S
World J Pediatr 2019 Apr;15(2):117-123. Epub 2018 Nov 21 doi: 10.1007/s12519-018-0203-1. PMID: 30465125
Cai JS, Qiang S, Bao-Bing Y
Scand J Gastroenterol 2017 Jan;52(1):34-43. Epub 2016 Sep 9 doi: 10.1080/00365521.2016.1224382. PMID: 27610642
Siriwardena AK, Siriwardena AM
BMJ 2014 Oct 31;349:g6385. doi: 10.1136/bmj.g6385. PMID: 25361852
Navaneethan U, Jayanthi V, Mohan P
Minerva Gastroenterol Dietol 2011 Mar;57(1):97-104. PMID: 21372774
Pannala R, Chari ST
Curr Opin Gastroenterol 2008 Sep;24(5):591-6. doi: 10.1097/MOG.0b013e32830b10d2. PMID: 19122500

Clinical prediction guides

Shen WJ, Chen G, Wang M, Zheng S
World J Pediatr 2019 Apr;15(2):117-123. Epub 2018 Nov 21 doi: 10.1007/s12519-018-0203-1. PMID: 30465125
Modha K
Tech Vasc Interv Radiol 2015 Dec;18(4):197-200. Epub 2015 Jul 16 doi: 10.1053/j.tvir.2015.07.002. PMID: 26615159
Sugumar A, Chari ST
J Gastroenterol Hepatol 2011 Sep;26(9):1368-73. doi: 10.1111/j.1440-1746.2011.06843.x. PMID: 21884246
Toomey DP, Swan N, Torreggiani W, Conlon KC
Br J Surg 2007 Sep;94(9):1067-74. doi: 10.1002/bjs.5893. PMID: 17701958
Goodnight JE Jr, Blaisdell FW
Surg Clin North Am 1981 Aug;61(4):973-9. doi: 10.1016/s0039-6109(16)42493-x. PMID: 7025304

Recent systematic reviews

Pang L, Wu S, Kong J
Digestion 2023;104(2):85-96. Epub 2023 Jan 6 doi: 10.1159/000528020. PMID: 36617409Free PMC Article
Rizzo A, Ricci AD, Frega G, Palloni A, DE Lorenzo S, Abbati F, Mollica V, Tavolari S, DI Marco M, Brandi G
In Vivo 2020 Jul-Aug;34(4):1701-1714. doi: 10.21873/invivo.11964. PMID: 32606139Free PMC Article
Moole H, Bechtold M, Puli SR
World J Surg Oncol 2016 Jul 11;14(1):182. doi: 10.1186/s12957-016-0933-2. PMID: 27400651Free PMC Article
Itoi T, Sofuni A, Itokawa F, Tsuchiya T, Kurihara T, Ishii K, Tsuji S, Ikeuchi N, Umeda J, Moriyasu F, Tsuchida A
J Hepatobiliary Pancreat Sci 2010 Sep;17(5):611-6. Epub 2009 Oct 6 doi: 10.1007/s00534-009-0196-1. PMID: 19806298
Garcea G, Ong SL, Dennison AR, Berry DP, Maddern GJ
Dig Dis Sci 2009 Jun;54(6):1184-98. Epub 2008 Sep 4 doi: 10.1007/s10620-008-0479-4. PMID: 18770035

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