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Disorder of lens

MedGen UID:: 44102
•Concept ID:: C0023308
•: Disease or Syndrome

Synonyms:	Disease, Lens; Diseases, Lens; Lens Disease; Lens Diseases
SNOMED CT:	Disorder of lens (10810001)

Definition

A non-neoplastic or neoplastic disorder that affects the lens of the eye. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDisorder of lens

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Disorder of eye region
        Disorder of lens
        Aphakia
        Congenital aphakia
        Artificial Lens Implant Migration
        Cataract
        Acquired Cataract
        Acquired Bilateral Cataracts
        Acquired Unilateral Cataract
        Age-related cataract
        Induced Cataract
        Bilateral cataracts
        Congenital Bilateral Cataracts
        Capsular cataract
        Posterior capsular cataract
        Cataract 20 multiple types
        Christmas tree cataract
        Cortical cataract
        Anterior cortical cataract
        Cortical Cataract Grade 1
        Cortical Cataract Grade 2
        Cortical Cataract Grade 3
        Cortical Cataract Grade 4
        Posterior cortical cataract
        Developmental cataract
        Congenital Unilateral Cataract
        Juvenile cataract
        Myotonic cataract
        Nuclear sclerotic cataract
        Nuclear Cataract Grade 1
        Nuclear Cataract Grade 2
        Nuclear Cataract Grade 3
        Nuclear Cataract Grade 4
        Polar cataract
        Anterior polar cataract
        Posterior polar cataract
        Posterior subcapsular cataract
        Iridescent posterior subcapsular cataract
        Juvenile posterior subcapsular lenticular opacities
        Posterior Subcapsular Cataract Grade 1
        Posterior Subcapsular Cataract Grade 2
        Posterior Subcapsular Cataract Grade 3
        Posterior Subcapsular Cataract Grade 4
        Presenile cataracts
        Progressive cataract
        Secondary cataract
        Subcapsular cataract
        Anterior subcapsular cataract
        Tetanic cataract
        Zonular cataract
        Cataract 5 multiple types
        Coralliform cataract
        Coronary cataract
        Nuclear cataract
        Punctate cataract
        Sutural cataract
        Congenital anomaly of lens
        Ectopia lentis
        Ectopia lentis 1, isolated, autosomal dominant
        Ectopia lentis 2, isolated, autosomal recessive
        Ectopia lentis et pupillae
        Lens luxation
        Lens subluxation

Professional guidelines

PubMed

Biology of Inherited Cataracts and Opportunities for Treatment.

Shiels A, Hejtmancik JF
Annu Rev Vis Sci 2019 Sep 15;5:123-149. doi: 10.1146/annurev-vision-091517-034346. PMID: 31525139 Free PMC Article

Conjunctivitis: a systematic review of diagnosis and treatment.

Azari AA, Barney NP
JAMA 2013 Oct 23;310(16):1721-9. doi: 10.1001/jama.2013.280318. PMID: 24150468 Free PMC Article

Congenital and infantile cataract: aetiology and management.

Chan WH, Biswas S, Ashworth JL, Lloyd IC
Eur J Pediatr 2012 Apr;171(4):625-30. Epub 2012 Mar 1 doi: 10.1007/s00431-012-1700-1. PMID: 22383071

See all (927)

Recent clinical studies

Etiology

Cataract surgical reach: Falling short to catch white cataracts!

Rewri P, Lohan A, Aggarwal S, Chodhary P, Singhal A
Indian J Ophthalmol 2021 Jun;69(6):1575-1578. doi: 10.4103/ijo.IJO_2560_20. PMID: 34011744 Free PMC Article

Prevalence and risk factors for age-related cataract in Sweden.

Hugosson M, Ekström C
Ups J Med Sci 2020 Nov;125(4):311-315. Epub 2020 Aug 6 doi: 10.1080/03009734.2020.1802375. PMID: 32757792 Free PMC Article

Cataracts.

Thompson J, Lakhani N
Prim Care 2015 Sep;42(3):409-23. doi: 10.1016/j.pop.2015.05.012. PMID: 26319346

Cataract prevalence and prevention in Europe: a literature review.

Prokofyeva E, Wegener A, Zrenner E
Acta Ophthalmol 2013 Aug;91(5):395-405. Epub 2012 Jun 20 doi: 10.1111/j.1755-3768.2012.02444.x. PMID: 22715900

Exfoliation syndrome.

Ritch R, Schlötzer-Schrehardt U
Surv Ophthalmol 2001 Jan-Feb;45(4):265-315. doi: 10.1016/s0039-6257(00)00196-x. PMID: 11166342

See all (13184)

Diagnosis

Detecting Cataract Using Smartphones.

Askarian B, Ho P, Chong JW
IEEE J Transl Eng Health Med 2021;9:3800110. Epub 2021 Apr 20 doi: 10.1109/JTEHM.2021.3074597. PMID: 34786216 Free PMC Article

Congenital Cataract and Its Genetics: The Era of Next-Generation Sequencing.

Taylan Şekeroğlu H, Utine GE
Turk J Ophthalmol 2021 Apr 29;51(2):107-113. doi: 10.4274/tjo.galenos.2020.08377. PMID: 33951899 Free PMC Article

Cataracts.

Thompson J, Lakhani N
Prim Care 2015 Sep;42(3):409-23. doi: 10.1016/j.pop.2015.05.012. PMID: 26319346

Cataract prevalence and prevention in Europe: a literature review.

Prokofyeva E, Wegener A, Zrenner E
Acta Ophthalmol 2013 Aug;91(5):395-405. Epub 2012 Jun 20 doi: 10.1111/j.1755-3768.2012.02444.x. PMID: 22715900

Congenital and infantile cataract: aetiology and management.

Chan WH, Biswas S, Ashworth JL, Lloyd IC
Eur J Pediatr 2012 Apr;171(4):625-30. Epub 2012 Mar 1 doi: 10.1007/s00431-012-1700-1. PMID: 22383071

See all (8204)

Therapy

Early vitrectomy for exogenous endophthalmitis following surgery.

Muqit MM, Mehat M, Bunce C, Bainbridge JW
Cochrane Database Syst Rev 2022 Nov 18;11(11):CD013760. doi: 10.1002/14651858.CD013760.pub2. PMID: 36398614 Free PMC Article

Topical corticosteroids for dry eye.

Liu SH, Saldanha IJ, Abraham AG, Rittiphairoj T, Hauswirth S, Gregory D, Ifantides C, Li T
Cochrane Database Syst Rev 2022 Oct 21;10(10):CD015070. doi: 10.1002/14651858.CD015070.pub2. PMID: 36269562 Free PMC Article

Minimally Invasive Glaucoma Surgical Techniques for Open-Angle Glaucoma: An Overview of Cochrane Systematic Reviews and Network Meta-analysis.

Bicket AK, Le JT, Azuara-Blanco A, Gazzard G, Wormald R, Bunce C, Hu K, Jayaram H, King A, Otárola F, Nikita E, Shah A, Stead R, Tóth M, Li T
JAMA Ophthalmol 2021 Sep 1;139(9):983-989. doi: 10.1001/jamaophthalmol.2021.2351. PMID: 34264292 Free PMC Article

N-acetylcarnosine (NAC) drops for age-related cataract.

Dubois VD, Bastawrous A
Cochrane Database Syst Rev 2017 Feb 28;2(2):CD009493. doi: 10.1002/14651858.CD009493.pub2. PMID: 28245346 Free PMC Article

Cataract prevalence and prevention in Europe: a literature review.

Prokofyeva E, Wegener A, Zrenner E
Acta Ophthalmol 2013 Aug;91(5):395-405. Epub 2012 Jun 20 doi: 10.1111/j.1755-3768.2012.02444.x. PMID: 22715900

See all (9413)

Prognosis

Congenital primary aphakia.

Ernst J, Medsinge A, Scanga HL, Hiasat J, Moore W, Ali A, Levin AV, Stahl ED, Nischal KK
J AAPOS 2022 Feb;26(1):4.e1-4.e5. Epub 2022 Jan 17 doi: 10.1016/j.jaapos.2021.09.008. PMID: 35051625

Congenital Cataract and Its Genetics: The Era of Next-Generation Sequencing.

Taylan Şekeroğlu H, Utine GE
Turk J Ophthalmol 2021 Apr 29;51(2):107-113. doi: 10.4274/tjo.galenos.2020.08377. PMID: 33951899 Free PMC Article

Incidence of cataract following implantation of a posterior-chamber phakic lens ICL (Implantable Collamer Lens) - long-term results.

Kocová H, Vlková E, Michalcová L, Rybárová N, Motyka O
Cesk Slov Oftalmol 2017 Fall;73(3):87-93. PMID: 29394074

Cataract.

Allen D
BMJ Clin Evid 2011 Feb 15;2011 PMID: 21718561 Free PMC Article

Cataract.

Allen D
BMJ Clin Evid 2008 Aug 14;2008 PMID: 19445812 Free PMC Article

See all (6283)

Clinical prediction guides

Congenital Cataract and Its Genetics: The Era of Next-Generation Sequencing.

Taylan Şekeroğlu H, Utine GE
Turk J Ophthalmol 2021 Apr 29;51(2):107-113. doi: 10.4274/tjo.galenos.2020.08377. PMID: 33951899 Free PMC Article

Cataract grading systems: a review of past and present.

Gali HE, Sella R, Afshari NA
Curr Opin Ophthalmol 2019 Jan;30(1):13-18. doi: 10.1097/ICU.0000000000000542. PMID: 30489359

Congenital and infantile cataract: aetiology and management.

Chan WH, Biswas S, Ashworth JL, Lloyd IC
Eur J Pediatr 2012 Apr;171(4):625-30. Epub 2012 Mar 1 doi: 10.1007/s00431-012-1700-1. PMID: 22383071

The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.

Chylack LT Jr, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY
Arch Ophthalmol 1993 Jun;111(6):831-6. doi: 10.1001/archopht.1993.01090060119035. PMID: 8512486

Traumatic cataract.

Ajamian PC
Optom Clin 1993;3(2):49-56. PMID: 8268696

See all (6444)

Recent systematic reviews

The Amyloid-β Pathway in Alzheimer's Disease.

Hampel H, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A
Mol Psychiatry 2021 Oct;26(10):5481-5503. Epub 2021 Aug 30 doi: 10.1038/s41380-021-01249-0. PMID: 34456336 Free PMC Article

Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study.

GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2021 Feb;9(2):e144-e160. Epub 2020 Dec 1 doi: 10.1016/S2214-109X(20)30489-7. PMID: 33275949 Free PMC Article

The Complications of Myopia: A Review and Meta-Analysis.

Haarman AEG, Enthoven CA, Tideman JWL, Tedja MS, Verhoeven VJM, Klaver CCW
Invest Ophthalmol Vis Sci 2020 Apr 9;61(4):49. doi: 10.1167/iovs.61.4.49. PMID: 32347918 Free PMC Article

Global causes of blindness and distance vision impairment 1990-2020: a systematic review and meta-analysis.

Flaxman SR, Bourne RRA, Resnikoff S, Ackland P, Braithwaite T, Cicinelli MV, Das A, Jonas JB, Keeffe J, Kempen JH, Leasher J, Limburg H, Naidoo K, Pesudovs K, Silvester A, Stevens GA, Tahhan N, Wong TY, Taylor HR; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2017 Dec;5(12):e1221-e1234. Epub 2017 Oct 11 doi: 10.1016/S2214-109X(17)30393-5. PMID: 29032195

Conjunctivitis: a systematic review of diagnosis and treatment.

Azari AA, Barney NP
JAMA 2013 Oct 23;310(16):1721-9. doi: 10.1001/jama.2013.280318. PMID: 24150468 Free PMC Article

See all (268)

MedGen

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Send to:

Disorder of lens

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

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