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Duodenogastric reflux

MedGen UID:
4420
•Concept ID:
C0013299
•
Disease or Syndrome
Synonyms: Duodenal Reflux; Duodenal Refluxs; Duodeno Gastric Reflux; Duodeno-Gastric Reflux; Duodenogastric Reflux; Reflux, Duodenal; Reflux, Duodeno-Gastric; Reflux, Duodenogastric
SNOMED CT: DGR - Duodenogastric reflux (9733003); Duodenogastric reflux (9733003)
 
Monarch Initiative: MONDO:0006735

Definition

Retrograde flow of duodenal contents (bile acids; pancreatic juice) into the stomach. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDuodenogastric reflux

Professional guidelines

PubMed

Consistent Efficacy of Wendan Decoction for the Treatment of Digestive Reflux Disorders.
Ling W, Huang Y, Xu JH, Li Y, Huang YM, Ling HB, Sui Y, Zhao HL
Am J Chin Med 2015;43(5):893-913. Epub 2015 Aug 4 doi: 10.1142/S0192415X15500524. PMID: 26243580
Review article: the role of bile and pepsin in the pathophysiology and treatment of gastro-oesophageal reflux disease.
Tack J
Aliment Pharmacol Ther 2006 Sep;24 Suppl 2:10-6. doi: 10.1111/j.1365-2036.2006.03040.x. PMID: 16939428
Truncal vagotomy, antrectomy and Roux-en-Y gastrojejunostomy in the treatment of duodenogastric reflux disease.
Civello IM, Brisinda G, Palermo A, Agresti M, Minelli S, Sganga G, Maria G
Dig Surg 1998;15(1):30-4. doi: 10.1159/000018583. PMID: 9845560

Recent clinical studies

Etiology

Bile reflux after bariatric surgery.
Dolores Frutos Bernal M
Cir Esp (Engl Ed) 2023 Oct;101 Suppl 4:S63-S68. Epub 2023 Nov 16 doi: 10.1016/j.cireng.2023.02.014. PMID: 37979939
The Relationship between Primary Duodenogastric Reflux and Helicobacter pylori Gastritis in Children.
Arslan M, Balamtekin N
Dig Dis 2022;40(3):276-281. Epub 2021 May 19 doi: 10.1159/000517263. PMID: 34010846
Effect of Duodenogastric Reflux on Dental Enamel.
Faraoni JJ, de Andrade JB, de Matos LLM, Palma-Dibb RG
Oral Health Prev Dent 2020 Sep 4;18:701-706. doi: 10.3290/j.ohpd.a45073. PMID: 32895652
Oxidative stress from reflux esophagitis to esophageal cancer: the alleviation with antioxidants.
Song JH, Han YM, Kim WH, Park JM, Jeong M, Go EJ, Hong SP, Hahm KB
Free Radic Res 2016 Oct;50(10):1071-1079. Epub 2016 May 19 doi: 10.1080/10715762.2016.1181262. PMID: 27109388
Duodenogastric reflux and foregut carcinogenesis.
Miwa K, Hattori T, Miyazaki I
Cancer 1995 Mar 15;75(6 Suppl):1426-32. doi: 10.1002/1097-0142(19950315)75:6+<1426::aid-cncr2820751506>3.0.co;2-#. PMID: 7889469

Diagnosis

Bile reflux after bariatric surgery.
Dolores Frutos Bernal M
Cir Esp (Engl Ed) 2023 Oct;101 Suppl 4:S63-S68. Epub 2023 Nov 16 doi: 10.1016/j.cireng.2023.02.014. PMID: 37979939
Duodenogastro-oesophageal reflux.
Vaezi MF, Richter JE
Baillieres Best Pract Res Clin Gastroenterol 2000 Oct;14(5):719-29. doi: 10.1053/bega.2000.0120. PMID: 11003805
Duodenogastric reflux: an update.
Girelli CM, Cuvello P, Limido E, Rocca F
Am J Gastroenterol 1996 Apr;91(4):648-53. PMID: 8677924
Alkaline reflux gastritis.
Burden WR, Hodges RP, Hsu M, O'Leary JP
Surg Clin North Am 1991 Feb;71(1):33-44. doi: 10.1016/s0039-6109(16)45331-4. PMID: 1989108
Nonulcer dyspepsia.
Thompson WG
Can Med Assoc J 1984 Mar 1;130(5):565-9. PMID: 6365298Free PMC Article

Therapy

Bile reflux after bariatric surgery.
Dolores Frutos Bernal M
Cir Esp (Engl Ed) 2023 Oct;101 Suppl 4:S63-S68. Epub 2023 Nov 16 doi: 10.1016/j.cireng.2023.02.014. PMID: 37979939
Systematic review: duodenogastroesophageal (biliary) reflux prevalence, symptoms, oesophageal lesions and treatment.
Basnayake C, Geeraerts A, Pauwels A, Koek G, Vaezi M, Vanuytsel T, Tack J
Aliment Pharmacol Ther 2021 Sep;54(6):755-778. Epub 2021 Jul 27 doi: 10.1111/apt.16533. PMID: 34313333
Effect of Duodenogastric Reflux on Dental Enamel.
Faraoni JJ, de Andrade JB, de Matos LLM, Palma-Dibb RG
Oral Health Prev Dent 2020 Sep 4;18:701-706. doi: 10.3290/j.ohpd.a45073. PMID: 32895652
Duodenogastro-oesophageal reflux.
Vaezi MF, Richter JE
Baillieres Best Pract Res Clin Gastroenterol 2000 Oct;14(5):719-29. doi: 10.1053/bega.2000.0120. PMID: 11003805
Alkaline reflux gastritis.
Burden WR, Hodges RP, Hsu M, O'Leary JP
Surg Clin North Am 1991 Feb;71(1):33-44. doi: 10.1016/s0039-6109(16)45331-4. PMID: 1989108

Prognosis

Pyloroplasty and the risk of Barrett's esophagus in patients with gastroparesis.
Alkhayyat M, Sanghi V, Qapaja T, Butler R, Rouphael C, McMichael J, Goldblum J, Sanaka MR, Thota PN
Dis Esophagus 2020 Nov 18;33(11) doi: 10.1093/dote/doaa049. PMID: 32556104Free PMC Article
Current status in remnant gastric cancer after distal gastrectomy.
Ohira M, Toyokawa T, Sakurai K, Kubo N, Tanaka H, Muguruma K, Yashiro M, Onoda N, Hirakawa K
World J Gastroenterol 2016 Feb 28;22(8):2424-33. doi: 10.3748/wjg.v22.i8.2424. PMID: 26937131Free PMC Article
Current status of function-preserving surgery for gastric cancer.
Saito T, Kurokawa Y, Takiguchi S, Mori M, Doki Y
World J Gastroenterol 2014 Dec 14;20(46):17297-304. doi: 10.3748/wjg.v20.i46.17297. PMID: 25516640Free PMC Article
Duodenogastro-oesophageal reflux.
Vaezi MF, Richter JE
Baillieres Best Pract Res Clin Gastroenterol 2000 Oct;14(5):719-29. doi: 10.1053/bega.2000.0120. PMID: 11003805
Nonulcer dyspepsia.
Thompson WG
Can Med Assoc J 1984 Mar 1;130(5):565-9. PMID: 6365298Free PMC Article

Clinical prediction guides

CHANGES IN SERUM SOMATOSTATIN AND GASTRIN LEVELS IN PATIENTS AFTER CHOLECYSTECTOMY AND GASTROESOPHAGEAL REFLUX DISEASE.
Sirchak YS, Kydybyts SS, Bedey NV, Chendey VI, Stan MP, Chobej SM
Wiad Lek 2023;76(3):548-553. doi: 10.36740/WLek202303113. PMID: 37057778
Pyloroplasty and the risk of Barrett's esophagus in patients with gastroparesis.
Alkhayyat M, Sanghi V, Qapaja T, Butler R, Rouphael C, McMichael J, Goldblum J, Sanaka MR, Thota PN
Dis Esophagus 2020 Nov 18;33(11) doi: 10.1093/dote/doaa049. PMID: 32556104Free PMC Article
Current status of function-preserving surgery for gastric cancer.
Saito T, Kurokawa Y, Takiguchi S, Mori M, Doki Y
World J Gastroenterol 2014 Dec 14;20(46):17297-304. doi: 10.3748/wjg.v20.i46.17297. PMID: 25516640Free PMC Article
Clinical value of endoscopy and histology in the diagnosis of duodenogastric reflux disease.
Stein HJ, Smyrk TC, DeMeester TR, Rouse J, Hinder RA
Surgery 1992 Oct;112(4):796-803; discussion 803-4. PMID: 1411953
Reflux gastritis.
Dixon MF
Acta Gastroenterol Belg 1989 May-Aug;52(3-4):292-6. PMID: 2637575

Recent systematic reviews

Systematic review: duodenogastroesophageal (biliary) reflux prevalence, symptoms, oesophageal lesions and treatment.
Basnayake C, Geeraerts A, Pauwels A, Koek G, Vaezi M, Vanuytsel T, Tack J
Aliment Pharmacol Ther 2021 Sep;54(6):755-778. Epub 2021 Jul 27 doi: 10.1111/apt.16533. PMID: 34313333
Consistent Efficacy of Wendan Decoction for the Treatment of Digestive Reflux Disorders.
Ling W, Huang Y, Xu JH, Li Y, Huang YM, Ling HB, Sui Y, Zhao HL
Am J Chin Med 2015;43(5):893-913. Epub 2015 Aug 4 doi: 10.1142/S0192415X15500524. PMID: 26243580
Common Mechanism of Pathogenesis in Gastrointestinal Diseases Implied by Consistent Efficacy of Single Chinese Medicine Formula: A PRISMA-Compliant Systematic Review and Meta-Analysis.
Ling W, Li Y, Jiang W, Sui Y, Zhao HL
Medicine (Baltimore) 2015 Jul;94(27):e1111. doi: 10.1097/MD.0000000000001111. PMID: 26166106Free PMC Article
Systematic review: the application of molecular pathogenesis to prevention and treatment of oesophageal adenocarcinoma.
Peters CJ, Fitzgerald RC
Aliment Pharmacol Ther 2007 Jun 1;25(11):1253-69. doi: 10.1111/j.1365-2036.2007.03325.x. PMID: 17509094

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