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X-Linked Inherited Disorder

MedGen UID:
443623
Concept ID:
C2828000
Disease or Syndrome

Definition

An inherited disorder affecting mostly males. It results from defective genes that are present on the X chromosome. [from NCI]

Professional guidelines

PubMed

Silva CAB, Andrade LGM, Vaisbich MH, Barreto FC
J Bras Nefrol 2022 Apr-Jun;44(2):249-267. doi: 10.1590/2175-8239-JBN-2021-0208. PMID: 35212703Free PMC Article
Hopkin RJ, Jefferies JL, Laney DA, Lawson VH, Mauer M, Taylor MR, Wilcox WR; Fabry Pediatric Expert Panel
Mol Genet Metab 2016 Feb;117(2):104-13. Epub 2015 Oct 23 doi: 10.1016/j.ymgme.2015.10.007. PMID: 26546059
Frank JE
Am Fam Physician 2005 Oct 1;72(7):1277-82. PMID: 16225031

Recent clinical studies

Etiology

Yoshida S, Kido J, Sawada T, Momosaki K, Sugawara K, Matsumoto S, Endo F, Nakamura K
Orphanet J Rare Dis 2020 Aug 26;15(1):220. doi: 10.1186/s13023-020-01494-6. PMID: 32843101Free PMC Article
Barman HA, Özcan S, Atıcı A, Özgökçe C, Öztürk A, Kafalı AE, Çakar NE, Tavşanlı ME, Küçük M, Şahin I, Okuyan E
Anatol J Cardiol 2020 Jan;23(2):79-85. doi: 10.14744/AnatolJCardiol.2019.84782. PMID: 32011328Free PMC Article
Olivieri LJ, Kellman P, McCarter RJ, Cross RR, Hansen MS, Spurney CF
J Cardiovasc Magn Reson 2016 Oct 28;18(1):72. doi: 10.1186/s12968-016-0292-8. PMID: 27788681Free PMC Article
de Winter CF, van Dijk F, Stolker JJ, Hennekam RC
J Intellect Disabil Res 2009 Apr;53(4):319-28. Epub 2009 Feb 2 doi: 10.1111/j.1365-2788.2009.01156.x. PMID: 19187102
Winter PC, Butler EE
Ulster Med J 1993 Apr;62(1):21-8. PMID: 8100097Free PMC Article

Diagnosis

Germain DP
Orphanet J Rare Dis 2010 Nov 22;5:30. doi: 10.1186/1750-1172-5-30. PMID: 21092187Free PMC Article
Sodi A, Bini A, Mignani R, Minuti B, Menchini U
Int Ophthalmol 2009 Oct;29(5):435-7. Epub 2008 Sep 11 doi: 10.1007/s10792-008-9252-0. PMID: 18784903
Frank JE
Am Fam Physician 2005 Oct 1;72(7):1277-82. PMID: 16225031
Mehndiratta MM, Rao KB, Garg S, Pandey S
J Assoc Physicians India 2005 Jun;53:562-3. PMID: 16121813
Nassogne MC, Sharrard M, Hertz-Pannier L, Armengaud D, Touati G, Delonlay-Debeney P, Zerah M, Brunelle F, Saudubray JM
Childs Nerv Syst 2002 Dec;18(12):729-31. Epub 2002 Jul 27 doi: 10.1007/s00381-002-0630-z. PMID: 12483361

Therapy

Umer M, Motwani M, Jefferies JL, Nagueh SF, Kalra DK
Curr Probl Cardiol 2023 Jan;48(1):101439. Epub 2022 Oct 4 doi: 10.1016/j.cpcardiol.2022.101439. PMID: 36202174
Dinu IR, Firu ŞG
Rom J Morphol Embryol 2021 Jan-Mar;62(1):5-11. doi: 10.47162/RJME.62.1.01. PMID: 34609404Free PMC Article
Germain DP
Orphanet J Rare Dis 2010 Nov 22;5:30. doi: 10.1186/1750-1172-5-30. PMID: 21092187Free PMC Article
Germain DP
Expert Opin Investig Drugs 2002 Oct;11(10):1467-76. doi: 10.1517/13543784.11.10.1467. PMID: 12387706
Cavazzana-Calvo M, Hacein-Bey S, de Saint Basile G, Gross F, Yvon E, Nusbaum P, Selz F, Hue C, Certain S, Casanova JL, Bousso P, Deist FL, Fischer A
Science 2000 Apr 28;288(5466):669-72. doi: 10.1126/science.288.5466.669. PMID: 10784449

Prognosis

Dowling P, Murphy S, Zweyer M, Raucamp M, Swandulla D, Ohlendieck K
Expert Rev Mol Diagn 2019 Aug;19(8):739-755. Epub 2019 Aug 2 doi: 10.1080/14737159.2019.1648214. PMID: 31359811
Chiarelli LR, Morera SM, Bianchi P, Fermo E, Zanella A, Galizzi A, Valentini G
PLoS One 2012;7(2):e32065. Epub 2012 Feb 14 doi: 10.1371/journal.pone.0032065. PMID: 22348148Free PMC Article
Frantz MC, Pontz BF, Arnold W
ORL J Otorhinolaryngol Relat Spec 2008;70(3):210-3. Epub 2008 Apr 8 doi: 10.1159/000124297. PMID: 18401198
Nassogne MC, Sharrard M, Hertz-Pannier L, Armengaud D, Touati G, Delonlay-Debeney P, Zerah M, Brunelle F, Saudubray JM
Childs Nerv Syst 2002 Dec;18(12):729-31. Epub 2002 Jul 27 doi: 10.1007/s00381-002-0630-z. PMID: 12483361
Sawaya RA, Mourad FH, Najjar S, Mikati M, Raymond GV
Eur Neurol 1999;42(3):169-72. doi: 10.1159/000008093. PMID: 10529544

Clinical prediction guides

Bayram E, Topcu Y, Akinci G, Hiz S, Cakmakci H
Ann Saudi Med 2013 Jan-Feb;33(1):73-5. doi: 10.5144/0256-4947.2012.01.7.1545. PMID: 22750766Free PMC Article
Chiarelli LR, Morera SM, Bianchi P, Fermo E, Zanella A, Galizzi A, Valentini G
PLoS One 2012;7(2):e32065. Epub 2012 Feb 14 doi: 10.1371/journal.pone.0032065. PMID: 22348148Free PMC Article
Friso A, Tomanin R, Alba S, Gasparotto N, Puicher EP, Fusco M, Hortelano G, Muenzer J, Marin O, Zacchello F, Scarpa M
J Gene Med 2005 Nov;7(11):1482-91. doi: 10.1002/jgm.790. PMID: 15966019
Germain DP
Expert Opin Investig Drugs 2002 Oct;11(10):1467-76. doi: 10.1517/13543784.11.10.1467. PMID: 12387706
Coude FX, Ogier H, Charpentier C, Thomassin G, Checoury A, Amedee-Manesme O, Saudubray JM, Frezal J
Hum Genet 1981;59(3):263-5. doi: 10.1007/BF00283677. PMID: 7199025

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