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Motion sickness

MedGen UID:
44503
•Concept ID:
C0026603
•
Disease or Syndrome
Synonyms: Motion Sickness; Sickness, Motion
SNOMED CT: Motion sickness (37031009); Travel sickness (37031009); Riders' vertigo (37031009)
 
Monarch Initiative: MONDO:0008015
OMIM®: 158280

Definition

A sensation of discomfort that results from a discordant relationship between visualized movement and any movement sensed by the vestibular system, which is characterized by dizziness, nausea, and vomiting. [from NCI]

Clinical features

From HPO
Abnormality of the nervous system
MedGen UID:
105425
•Concept ID:
C0497552
•
Congenital Abnormality
An abnormality of the nervous system.
See: Feature record | Search on this feature

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMotion sickness

Professional guidelines

PubMed

Motion sickness: current concepts and management.
Keshavarz B, Golding JF
Curr Opin Neurol 2022 Feb 1;35(1):107-112. doi: 10.1097/WCO.0000000000001018. PMID: 34839340
Management of postoperative nausea and vomiting in adults: current controversies.
Rajan N, Joshi GP
Curr Opin Anaesthesiol 2021 Dec 1;34(6):695-702. doi: 10.1097/ACO.0000000000001063. PMID: 34560688
The Neurophysiology and Treatment of Motion Sickness.
Koch A, Cascorbi I, Westhofen M, Dafotakis M, Klapa S, Kuhtz-Buschbeck JP
Dtsch Arztebl Int 2018 Oct 12;115(41):687-696. doi: 10.3238/arztebl.2018.0687. PMID: 30406755Free PMC Article

Recent clinical studies

Etiology

Motion sickness: current concepts and management.
Keshavarz B, Golding JF
Curr Opin Neurol 2022 Feb 1;35(1):107-112. doi: 10.1097/WCO.0000000000001018. PMID: 34839340
Chronic Dizziness.
Cha YH
Continuum (Minneap Minn) 2021 Apr 1;27(2):420-446. doi: 10.1212/CON.0000000000000932. PMID: 34351113
Motion sickness.
Golding JF
Handb Clin Neurol 2016;137:371-90. doi: 10.1016/B978-0-444-63437-5.00027-3. PMID: 27638085
Self-driving carsickness.
Diels C, Bos JE
Appl Ergon 2016 Mar;53 Pt B:374-82. Epub 2015 Oct 9 doi: 10.1016/j.apergo.2015.09.009. PMID: 26446454
Motion sickness.
Golding JF, Gresty MA
Curr Opin Neurol 2005 Feb;18(1):29-34. doi: 10.1097/00019052-200502000-00007. PMID: 15655399

Diagnosis

Chronic Dizziness.
Cha YH
Continuum (Minneap Minn) 2021 Apr 1;27(2):420-446. doi: 10.1212/CON.0000000000000932. PMID: 34351113
Advice for travelers.
Med Lett Drugs Ther 2019 Oct 7;61(1582):153-160. PMID: 31599872
The Neurophysiology and Treatment of Motion Sickness.
Koch A, Cascorbi I, Westhofen M, Dafotakis M, Klapa S, Kuhtz-Buschbeck JP
Dtsch Arztebl Int 2018 Oct 12;115(41):687-696. doi: 10.3238/arztebl.2018.0687. PMID: 30406755Free PMC Article
Motion Sickness: Current Knowledge and Recent Advance.
Zhang LL, Wang JQ, Qi RR, Pan LL, Li M, Cai YL
CNS Neurosci Ther 2016 Jan;22(1):15-24. Epub 2015 Oct 9 doi: 10.1111/cns.12468. PMID: 26452639Free PMC Article
Space motion sickness.
Lackner JR, Dizio P
Exp Brain Res 2006 Nov;175(3):377-99. Epub 2006 Oct 5 doi: 10.1007/s00221-006-0697-y. PMID: 17021896

Therapy

The Neurophysiology and Treatment of Motion Sickness.
Koch A, Cascorbi I, Westhofen M, Dafotakis M, Klapa S, Kuhtz-Buschbeck JP
Dtsch Arztebl Int 2018 Oct 12;115(41):687-696. doi: 10.3238/arztebl.2018.0687. PMID: 30406755Free PMC Article
Evidence-based analysis of risk factors for postoperative nausea and vomiting.
Apfel CC, Heidrich FM, Jukar-Rao S, Jalota L, Hornuss C, Whelan RP, Zhang K, Cakmakkaya OS
Br J Anaesth 2012 Nov;109(5):742-53. Epub 2012 Oct 3 doi: 10.1093/bja/aes276. PMID: 23035051
Sensation of presence and cybersickness in applications of virtual reality for advanced rehabilitation.
Kiryu T, So RH
J Neuroeng Rehabil 2007 Sep 25;4:34. doi: 10.1186/1743-0003-4-34. PMID: 17894857Free PMC Article
Space motion sickness.
Lackner JR, Dizio P
Exp Brain Res 2006 Nov;175(3):377-99. Epub 2006 Oct 5 doi: 10.1007/s00221-006-0697-y. PMID: 17021896
Motion sickness.
Golding JF, Gresty MA
Curr Opin Neurol 2005 Feb;18(1):29-34. doi: 10.1097/00019052-200502000-00007. PMID: 15655399

Prognosis

Motion sickness.
Golding JF
Handb Clin Neurol 2016;137:371-90. doi: 10.1016/B978-0-444-63437-5.00027-3. PMID: 27638085
Motion Sickness: Current Knowledge and Recent Advance.
Zhang LL, Wang JQ, Qi RR, Pan LL, Li M, Cai YL
CNS Neurosci Ther 2016 Jan;22(1):15-24. Epub 2015 Oct 9 doi: 10.1111/cns.12468. PMID: 26452639Free PMC Article
Self-driving carsickness.
Diels C, Bos JE
Appl Ergon 2016 Mar;53 Pt B:374-82. Epub 2015 Oct 9 doi: 10.1016/j.apergo.2015.09.009. PMID: 26446454
Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting.
Horn CC, Wallisch WJ, Homanics GE, Williams JP
Eur J Pharmacol 2014 Jan 5;722:55-66. Epub 2013 Oct 26 doi: 10.1016/j.ejphar.2013.10.037. PMID: 24495419Free PMC Article
Motion sickness.
Bles W, Bos JE, Kruit H
Curr Opin Neurol 2000 Feb;13(1):19-25. doi: 10.1097/00019052-200002000-00005. PMID: 10719645

Clinical prediction guides

Motion sickness.
Golding JF
Handb Clin Neurol 2016;137:371-90. doi: 10.1016/B978-0-444-63437-5.00027-3. PMID: 27638085
Motion Sickness: Current Knowledge and Recent Advance.
Zhang LL, Wang JQ, Qi RR, Pan LL, Li M, Cai YL
CNS Neurosci Ther 2016 Jan;22(1):15-24. Epub 2015 Oct 9 doi: 10.1111/cns.12468. PMID: 26452639Free PMC Article
Self-driving carsickness.
Diels C, Bos JE
Appl Ergon 2016 Mar;53 Pt B:374-82. Epub 2015 Oct 9 doi: 10.1016/j.apergo.2015.09.009. PMID: 26446454
Space motion sickness.
Lackner JR, Dizio P
Exp Brain Res 2006 Nov;175(3):377-99. Epub 2006 Oct 5 doi: 10.1007/s00221-006-0697-y. PMID: 17021896
Motion sickness.
Bles W, Bos JE, Kruit H
Curr Opin Neurol 2000 Feb;13(1):19-25. doi: 10.1097/00019052-200002000-00005. PMID: 10719645

Recent systematic reviews

Pharmacological and non-pharmacological countermeasures to Space Motion Sickness: a systematic review.
Khalid A, Prusty PP, Arshad I, Gustafson HE, Jalaly I, Nockels K, Bentley BL, Goel R, Ferrè ER
Front Neural Circuits 2023;17:1150233. Epub 2023 Jun 16 doi: 10.3389/fncir.2023.1150233. PMID: 37396400Free PMC Article
Clinical characteristics of visual motion hypersensitivity: a systematic review.
Wibble T, Pansell T
Exp Brain Res 2023 Jul;241(7):1707-1719. Epub 2023 Jun 21 doi: 10.1007/s00221-023-06652-3. PMID: 37341755Free PMC Article
Neural networks involved in nausea in adult humans: A systematic review.
Varangot-Reille C, Sanger GJ, Andrews PLR, Herranz-Gomez A, Suso-Martí L, de la Nava J, Cuenca-Martínez F
Auton Neurosci 2023 Mar;245:103059. Epub 2022 Dec 20 doi: 10.1016/j.autneu.2022.103059. PMID: 36580746
Antihistamines for motion sickness.
Karrim N, Byrne R, Magula N, Saman Y
Cochrane Database Syst Rev 2022 Oct 17;10(10):CD012715. doi: 10.1002/14651858.CD012715.pub2. PMID: 36250781Free PMC Article
Scopolamine (hyoscine) for preventing and treating motion sickness.
Spinks A, Wasiak J
Cochrane Database Syst Rev 2011 Jun 15;2011(6):CD002851. doi: 10.1002/14651858.CD002851.pub4. PMID: 21678338Free PMC Article

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