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Abortion, Septic

MedGen UID:
45
•Concept ID:
C0000817
•
Pathologic Function
Synonyms: Abortions, Septic; Septic Abortion; Septic Abortions

Definition

Any type of abortion, induced or spontaneous, that is associated with infection of the UTERUS and its appendages. It is characterized by FEVER, uterine tenderness, and foul discharge. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbortion, Septic

Professional guidelines

PubMed

Outcomes and management of pregnancy and puerperal group A streptococcal infections: A systematic review.
Harris K, Proctor LK, Shinar S, Philippopoulos E, Yudin MH, Murphy KE
Acta Obstet Gynecol Scand 2023 Feb;102(2):138-157. Epub 2023 Jan 12 doi: 10.1111/aogs.14500. PMID: 36636775Free PMC Article
Management of spontaneous abortion.
Griebel CP, Halvorsen J, Golemon TB, Day AA
Am Fam Physician 2005 Oct 1;72(7):1243-50. PMID: 16225027
Septic abortion--current management.
Caillouette JC
Calif Med 1970 Dec;113(6):44. PMID: 5486523Free PMC Article

Recent clinical studies

Etiology

Induced abortion.
ESHRE Capri Workshop Group
Hum Reprod 2017 Jun 1;32(6):1160-1169. doi: 10.1093/humrep/dex071. PMID: 28402552
Antibiotics for treating septic abortion.
Udoh A, Effa EE, Oduwole O, Okusanya BO, Okafo O
Cochrane Database Syst Rev 2016 Jul 1;7(7):CD011528. doi: 10.1002/14651858.CD011528.pub2. PMID: 27364644Free PMC Article
Obstetric infections.
Lapinsky SE
Crit Care Clin 2013 Jul;29(3):509-20. Epub 2013 Apr 30 doi: 10.1016/j.ccc.2013.03.006. PMID: 23830651
Management of spontaneous abortion.
Griebel CP, Halvorsen J, Golemon TB, Day AA
Am Fam Physician 2005 Oct 1;72(7):1243-50. PMID: 16225027
Spontaneous abortion.
McBride WZ
Am Fam Physician 1991 Jan;43(1):175-82. PMID: 1986486

Diagnosis

Induced abortion.
ESHRE Capri Workshop Group
Hum Reprod 2017 Jun 1;32(6):1160-1169. doi: 10.1093/humrep/dex071. PMID: 28402552
Maternal sepsis.
Morgan J, Roberts S
Obstet Gynecol Clin North Am 2013 Mar;40(1):69-87. doi: 10.1016/j.ogc.2012.11.007. PMID: 23466138
Management of spontaneous abortion.
Griebel CP, Halvorsen J, Golemon TB, Day AA
Am Fam Physician 2005 Oct 1;72(7):1243-50. PMID: 16225027
Septic abortion.
Stubblefield PG, Grimes DA
N Engl J Med 1994 Aug 4;331(5):310-4. doi: 10.1056/NEJM199408043310507. PMID: 8022443
Spontaneous abortion.
McBride WZ
Am Fam Physician 1991 Jan;43(1):175-82. PMID: 1986486

Therapy

Induced abortion.
ESHRE Capri Workshop Group
Hum Reprod 2017 Jun 1;32(6):1160-1169. doi: 10.1093/humrep/dex071. PMID: 28402552
Antibiotics for treating septic abortion.
Udoh A, Effa EE, Oduwole O, Okusanya BO, Okafo O
Cochrane Database Syst Rev 2016 Jul 1;7(7):CD011528. doi: 10.1002/14651858.CD011528.pub2. PMID: 27364644Free PMC Article
Treating spontaneous and induced septic abortions.
Eschenbach DA
Obstet Gynecol 2015 May;125(5):1042-1048. doi: 10.1097/AOG.0000000000000795. PMID: 25932831
Obstetric infections.
Lapinsky SE
Crit Care Clin 2013 Jul;29(3):509-20. Epub 2013 Apr 30 doi: 10.1016/j.ccc.2013.03.006. PMID: 23830651
Septic shock.
Sagarra M
Minn Med 1970 Apr;53(4):387-8. PMID: 5444022

Prognosis

Induced abortion.
ESHRE Capri Workshop Group
Hum Reprod 2017 Jun 1;32(6):1160-1169. doi: 10.1093/humrep/dex071. PMID: 28402552
Septic abortion.
Stubblefield PG, Grimes DA
N Engl J Med 1994 Aug 4;331(5):310-4. doi: 10.1056/NEJM199408043310507. PMID: 8022443
Abortion: epidemiology, safety, and technique.
Blumenthal PD
Curr Opin Obstet Gynecol 1992 Aug;4(4):506-12. PMID: 1504270
Spontaneous abortion.
McBride WZ
Am Fam Physician 1991 Jan;43(1):175-82. PMID: 1986486
Spontaneous abortion.
Boyd ME
Can J Surg 1989 Jul;32(4):260-4. PMID: 2660972

Clinical prediction guides

Disseminated intravascular coagulation in pregnancy: insights in pathophysiology, diagnosis and management.
Erez O, Mastrolia SA, Thachil J
Am J Obstet Gynecol 2015 Oct;213(4):452-63. Epub 2015 Mar 31 doi: 10.1016/j.ajog.2015.03.054. PMID: 25840271
Maternal sepsis: a Scottish population-based case-control study.
Acosta CD, Bhattacharya S, Tuffnell D, Kurinczuk JJ, Knight M
BJOG 2012 Mar;119(4):474-83. Epub 2012 Jan 18 doi: 10.1111/j.1471-0528.2011.03239.x. PMID: 22251396Free PMC Article
Inflammatory agents involved in septic miscarriage.
Aisemberg J, Vercelli C, Wolfson M, Salazar AI, Osycka-Salut C, Billi S, Ribeiro ML, Farina M, Franchi AM
Neuroimmunomodulation 2010;17(3):150-2. Epub 2010 Feb 4 doi: 10.1159/000258710. PMID: 20134189
The clinical course of patients with septic abortion admitted to an intensive care unit.
Finkielman JD, De Feo FD, Heller PG, Afessa B
Intensive Care Med 2004 Jun;30(6):1097-102. Epub 2004 Mar 9 doi: 10.1007/s00134-004-2207-7. PMID: 15007546
Postabortal sepsis.
Maitra N, Mani R, Trivedi C, Hazra M
J Indian Med Assoc 1994 Aug;92(8):266-7. PMID: 7963615

Recent systematic reviews

Antibiotics for treating septic abortion.
Udoh A, Effa EE, Oduwole O, Okusanya BO, Okafo O
Cochrane Database Syst Rev 2016 Jul 1;7(7):CD011528. doi: 10.1002/14651858.CD011528.pub2. PMID: 27364644Free PMC Article
Use of combined oral contraceptives post abortion.
Gaffield ME, Kapp N, Ravi A
Contraception 2009 Oct;80(4):355-62. Epub 2009 Jun 4 doi: 10.1016/j.contraception.2009.04.005. PMID: 19751858

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