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Epiphysiolysis

MedGen UID:: 4510
•Concept ID:: C0014571
•: Disease or Syndrome

Synonyms:

Epiphyses, Slipped; Epiphysiolyses; Slipped Epiphyses

Definition

Abnormal separation of an epiphysis from the shaft of a bone. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVEpiphysiolysis

Pathological process
- Disease
  - Disorder by Site
    - Connective and Soft Tissue Disorder
      - Musculoskeletal system disorder
        Disorder of bone
        Epiphysiolysis
        Proximal femoral epiphysiolysis

Professional guidelines

PubMed

Early GH Treatment Is Effective and Well Tolerated in Children With Turner Syndrome: NordiNet® IOS and Answer Program.

Backeljauw P, Blair JC, Ferran JM, Kelepouris N, Miller BS, Pietropoli A, Polak M, Sävendahl L, Verlinde F, Rohrer TR
J Clin Endocrinol Metab 2023 Sep 18;108(10):2653-2665. doi: 10.1210/clinem/dgad159. PMID: 36947589 Free PMC Article

Trends in the Presentation, Management, and Outcomes of Little League Shoulder.

Heyworth BE, Kramer DE, Martin DJ, Micheli LJ, Kocher MS, Bae DS
Am J Sports Med 2016 Jun;44(6):1431-8. Epub 2016 Mar 16 doi: 10.1177/0363546516632744. PMID: 26983458

Treatment in fractures of the odontoid process.

Fujii E, Kobayashi K, Hirabayashi K
Spine (Phila Pa 1976) 1988 Jun;13(6):604-9. PMID: 3175749

See all (4)

Recent clinical studies

Etiology

The torsion of the proximal femur in cementless total hip arthroplasty: a 3-dimensional evaluation.

Wettstein M, Mouhsine E, Aubaniac JM, Audigé L, Ollivier M, Leyvraz PF, Argenson JN
Hip Int 2023 Mar;33(2):254-261. Epub 2021 Aug 26 doi: 10.1177/11207000211037196. PMID: 34445907

The Feasibility of C1-C2 Screw-rod Fixation in the Children 5 Years of Age and Younger.

Burkhardt BW, Podolski W, Pitzen TR, Ruf M
J Pediatr Orthop 2021 Sep 1;41(8):e651-e658. doi: 10.1097/BPO.0000000000001899. PMID: 34238864

Hip pathology in Majewski osteodysplastic primordial dwarfism type II.

Karatas AF, Bober MB, Rogers K, Duker AL, Ditro CP, Mackenzie WG
J Pediatr Orthop 2014 Sep;34(6):585-90. doi: 10.1097/BPO.0000000000000183. PMID: 24705347

Shoulder injuries in the skeletally immature baseball pitcher and recommendations for the prevention of injury.

Zaremski JL, Krabak BJ
PM R 2012 Jul;4(7):509-16. doi: 10.1016/j.pmrj.2012.04.005. PMID: 22814728

Patterns of osteoarthritis of the hip.

Solomon L
J Bone Joint Surg Br 1976 May;58(2):176-83. doi: 10.1302/0301-620X.58B2.932079. PMID: 932079

See all (39)

Diagnosis

The torsion of the proximal femur in cementless total hip arthroplasty: a 3-dimensional evaluation.

Wettstein M, Mouhsine E, Aubaniac JM, Audigé L, Ollivier M, Leyvraz PF, Argenson JN
Hip Int 2023 Mar;33(2):254-261. Epub 2021 Aug 26 doi: 10.1177/11207000211037196. PMID: 34445907

Slipped capital femoral epiphysis: Diagnostic pitfalls and therapeutic options.

Panuccio E, Priano D, Caccavella V, Memeo A
Pediatr Med Chir 2022 Oct 28;44(s1) doi: 10.4081/pmc.2022.296. PMID: 37184314

Transphyseal elbow fracture in newborn: review of literature.

Ratti C, Guindani N, Riva G, Callegari L, Grassi FA, Murena L
Musculoskelet Surg 2015 Sep;99 Suppl 1:S99-105. Epub 2015 May 10 doi: 10.1007/s12306-015-0366-z. PMID: 25957551

Upper and lower limb length equalization: diagnosis, limb lengthening and curtailment, epiphysiodesis.

Burnei G, Vlad C, Gavriliu S, Georgescu I, Hodorogea D, Pârvan A, Burnei C, El Nayef T, Drăghici I
Rom J Intern Med 2012 Jan-Mar;50(1):43-59. PMID: 22788093

Patterns of osteoarthritis of the hip.

Solomon L
J Bone Joint Surg Br 1976 May;58(2):176-83. doi: 10.1302/0301-620X.58B2.932079. PMID: 932079

See all (47)

Therapy

Early GH Treatment Is Effective and Well Tolerated in Children With Turner Syndrome: NordiNet® IOS and Answer Program.

Long-Term Improvement and Safety of Aripiprazole for Irritability and Adaptive Function in Asian Children and Adolescents with Autistic Disorder: A 52-Week, Multinational, Multicenter, Open-Label Study.

Kim BU, Kim HW, Park EJ, Kim JH, Boon-Yasidhi V, Tarugsa J, Reyes A, Manalo SG, Joung YS
J Child Adolesc Psychopharmacol 2022 Sep;32(7):390-399. doi: 10.1089/cap.2022.0004. PMID: 36112116

Effectiveness and Overall Safety of NutropinAq(®) for Growth Hormone Deficiency and Other Paediatric Growth Hormone Disorders: Completion of the International Cooperative Growth Study, NutropinAq(®) European Registry (iNCGS).

Coutant R, Bosch Muñoz J, Dumitrescu CP, Schnabel D, Sert C, Perrot V, Dattani M
Front Endocrinol (Lausanne) 2021;12:676083. Epub 2021 May 25 doi: 10.3389/fendo.2021.676083. PMID: 34113318 Free PMC Article

Epiphysiolysis of the femoral neck due to closed reduction of an adolescent hip dislocation with a 4-year follow-up: a case report and review of the literature.

Rajani R, Wise B, Oswald T, Roberson J
J Pediatr Orthop B 2015 Jan;24(1):40-5. doi: 10.1097/BPB.0000000000000118. PMID: 25438107

1,25-dihydroxycholecalciferol in renal osteodystrophy. Epiphysiolysis--anticonvulsant therapy.

Pierides AM, Ellis HA, Dellagrammatikas H, Scott JE, Norman AW
Arch Dis Child 1977 Jun;52(6):464-72. doi: 10.1136/adc.52.6.464. PMID: 879832 Free PMC Article

See all (20)

Prognosis

Slipped capital femoral epiphysis: Diagnostic pitfalls and therapeutic options.

Panuccio E, Priano D, Caccavella V, Memeo A
Pediatr Med Chir 2022 Oct 28;44(s1) doi: 10.4081/pmc.2022.296. PMID: 37184314

Transphyseal elbow fracture in newborn: review of literature.

Ratti C, Guindani N, Riva G, Callegari L, Grassi FA, Murena L
Musculoskelet Surg 2015 Sep;99 Suppl 1:S99-105. Epub 2015 May 10 doi: 10.1007/s12306-015-0366-z. PMID: 25957551

Pediatric distal forearm and wrist injury: an imaging review.

Little JT, Klionsky NB, Chaturvedi A, Soral A, Chaturvedi A
Radiographics 2014 Mar-Apr;34(2):472-90. doi: 10.1148/rg.342135073. PMID: 24617692

Osteitis pubis in athletes. Infection, inflammation or injury?

Fricker PA, Taunton JE, Ammann W
Sports Med 1991 Oct;12(4):266-79. doi: 10.2165/00007256-199112040-00005. PMID: 1784877

See all (27)

Clinical prediction guides

Early GH Treatment Is Effective and Well Tolerated in Children With Turner Syndrome: NordiNet® IOS and Answer Program.

Kim BU, Kim HW, Park EJ, Kim JH, Boon-Yasidhi V, Tarugsa J, Reyes A, Manalo SG, Joung YS
J Child Adolesc Psychopharmacol 2022 Sep;32(7):390-399. doi: 10.1089/cap.2022.0004. PMID: 36112116

Intraoperative blood salvage in proximal femur epiphysiolysis surgical treatment with hip controlled dislocation technique: a case series study.

Colares PGB, Carlos LMB, Ramos MCMF, Campos CPS, Nascimento VDD, Cassiano JGM, Valente TM
Braz J Anesthesiol 2021 Sep-Oct;71(5):545-549. Epub 2021 Jun 11 doi: 10.1016/j.bjane.2021.02.061. PMID: 34097945 Free PMC Article

The role of trauma mechanism, fracture pattern and fixation technique on clinical outcomes and epiphyseal growth arrest in the surgical treatment of distal tibial epiphysiolysis.

Aslantaş FÇ, Yalın M, İlter MH, Bayrak A, Edipoğlu E, Tanrıverdi B, Duramaz A, Bilgili MG
Ulus Travma Acil Cerrahi Derg 2020 May;26(3):425-430. doi: 10.14744/tjtes.2019.27354. PMID: 32436969

Proximal femoral epiphysiolysis in the neonate.

Ogden JA, Lee KE, Rudicel SA, Pelker RR
J Pediatr Orthop 1984 May;4(3):285-92. doi: 10.1097/01241398-198405000-00002. PMID: 6736231

See all (17)

Recent systematic reviews

Mechanism and predisposing factors for proximal tibial epiphysiolysis in adolescents during sports activities.

Steiger CN, Ceroni D
Int Orthop 2019 Jun;43(6):1395-1403. Epub 2018 Sep 29 doi: 10.1007/s00264-018-4168-4. PMID: 30267244

See all (1)

MedGen

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Epiphysiolysis

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity