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Congenital megaureter

MedGen UID:
451022
Concept ID:
C0266324
Congenital Abnormality
Synonyms: Congenital dilatation of ureter; Congenital megaloureter
SNOMED CT: Congenital dilatation of ureter (718485003); Congenital megaloureter (718485003); Congenital megaureter (718485003)
 
HPO: HP:0008676

Definition

A developmental disturbance with extreme ureteral dilatation. [from HPO]

Term Hierarchy

Conditions with this feature

Congenital anomalies of kidney and urinary tract 2
MedGen UID:
1804316
Concept ID:
C5574705
Disease or Syndrome
Congenital anomalies of the kidneys and urinary tract (CAKUT) encompasses a spectrum of developmental disorders of the urinary tract that can range from mild vesicoureteral reflux to severe renal agenesis. Other phenotypes include renal duplication, small kidneys, ureteropelvic junction obstruction, hydronephrosis, and renal dysplasia. These abnormalities can result in kidney damage, and possibly renal failure (summary by Vivante et al., 2015). For a discussion of genetic heterogeneity of CAKUT, see 610805.

Professional guidelines

PubMed

Farrugia MK, Hitchcock R, Radford A, Burki T, Robb A, Murphy F; British Association of Paediatric Urologists
J Pediatr Urol 2014 Feb;10(1):26-33. Epub 2013 Oct 16 doi: 10.1016/j.jpurol.2013.09.018. PMID: 24206785
Caione P, Patricolo M, Lais A, Capitanucci ML, Capozza N, Ferro F
Fetal Diagn Ther 1996 May-Jun;11(3):205-9. doi: 10.1159/000264303. PMID: 8739588

Recent clinical studies

Etiology

Chu H, Cao YS, Deng QF, Mao CK
J Endourol 2023 Aug;37(8):889-894. Epub 2023 Jul 3 doi: 10.1089/end.2022.0834. PMID: 37265149
Ahram DF, Lim TY, Ke J, Jin G, Verbitsky M, Bodria M, Kil BH, Chatterjee D, Piva SE, Marasa M, Zhang JY, Cocchi E, Caridi G, Gucev Z, Lozanovski VJ, Pisani I, Izzi C, Savoldi G, Gnutti B, Capone VP, Morello W, Guarino S, Esposito P, Lambert S, Radhakrishnan J, Appel GB, Uy NS, Rao MK, Canetta PA, Bomback AS, Nestor JG, Hays T, Cohen DJ, Finale C, Wijk JAEV, La Scola C, Baraldi O, Tondolo F, Di Renzo D, Jamry-Dziurla A, Pezzutto A, Manca V, Mitrotti A, Santoro D, Conti G, Martino M, Giordano M, Gesualdo L, Zibar L, Masnata G, Bonomini M, Alberti D, La Manna G, Caliskan Y, Ranghino A, Marzuillo P, Kiryluk K, Krzemień G, Miklaszewska M, Lin F, Montini G, Scolari F, Fiaccadori E, Arapović A, Saraga M, McKiernan J, Alam S, Zaniew M, Szczepańska M, Szmigielska A, Sikora P, Drożdż D, Mizerska-Wasiak M, Mane S, Lifton RP, Tasic V, Latos-Bielenska A, Gharavi AG, Ghiggeri GM, Materna-Kiryluk A, Westland R, Sanna-Cherchi S
J Am Soc Nephrol 2023 Jun 1;34(6):1105-1119. Epub 2023 Mar 30 doi: 10.1681/ASN.0000000000000132. PMID: 36995132Free PMC Article
Fu W, Zhang X, Zhang X, Zhang P, Gao J, Dong J, Chen G, Xu A, Ma X, Li H, Shi L
PLoS One 2014;9(6):e99777. Epub 2014 Jun 12 doi: 10.1371/journal.pone.0099777. PMID: 24924420Free PMC Article
Biyani CS, Powell CS
J Endourol 2001 Oct;15(8):797-9. doi: 10.1089/089277901753205771. PMID: 11724117
Walsh G, Dubbins PA
AJR Am J Roentgenol 1996 Oct;167(4):897-900. doi: 10.2214/ajr.167.4.8819378. PMID: 8819378

Diagnosis

Ahram DF, Lim TY, Ke J, Jin G, Verbitsky M, Bodria M, Kil BH, Chatterjee D, Piva SE, Marasa M, Zhang JY, Cocchi E, Caridi G, Gucev Z, Lozanovski VJ, Pisani I, Izzi C, Savoldi G, Gnutti B, Capone VP, Morello W, Guarino S, Esposito P, Lambert S, Radhakrishnan J, Appel GB, Uy NS, Rao MK, Canetta PA, Bomback AS, Nestor JG, Hays T, Cohen DJ, Finale C, Wijk JAEV, La Scola C, Baraldi O, Tondolo F, Di Renzo D, Jamry-Dziurla A, Pezzutto A, Manca V, Mitrotti A, Santoro D, Conti G, Martino M, Giordano M, Gesualdo L, Zibar L, Masnata G, Bonomini M, Alberti D, La Manna G, Caliskan Y, Ranghino A, Marzuillo P, Kiryluk K, Krzemień G, Miklaszewska M, Lin F, Montini G, Scolari F, Fiaccadori E, Arapović A, Saraga M, McKiernan J, Alam S, Zaniew M, Szczepańska M, Szmigielska A, Sikora P, Drożdż D, Mizerska-Wasiak M, Mane S, Lifton RP, Tasic V, Latos-Bielenska A, Gharavi AG, Ghiggeri GM, Materna-Kiryluk A, Westland R, Sanna-Cherchi S
J Am Soc Nephrol 2023 Jun 1;34(6):1105-1119. Epub 2023 Mar 30 doi: 10.1681/ASN.0000000000000132. PMID: 36995132Free PMC Article
Farrugia MK, Hitchcock R, Radford A, Burki T, Robb A, Murphy F; British Association of Paediatric Urologists
J Pediatr Urol 2014 Feb;10(1):26-33. Epub 2013 Oct 16 doi: 10.1016/j.jpurol.2013.09.018. PMID: 24206785
Li TR, Du XK, Huo TL
Chin Med Sci J 2011 Jun;26(2):103-8. doi: 10.1016/s1001-9294(11)60028-x. PMID: 21703118
Vlad M, Ionescu N, Ispas AT, Ungureanu E, Stoica C
Rom J Morphol Embryol 2007;48(4):381-90. PMID: 18060188
Lockhart JL, Singer AM, Glenn JF
J Urol 1979 Sep;122(3):310-4. doi: 10.1016/s0022-5347(17)56380-6. PMID: 470000

Therapy

Ghersin E, Brook OR, Meretik S, Kaftori JK, Ofer A, Amendola MA, Engel A
AJR Am J Roentgenol 2004 Dec;183(6):1691-6. doi: 10.2214/ajr.183.6.01831691. PMID: 15547210

Prognosis

Ahram DF, Lim TY, Ke J, Jin G, Verbitsky M, Bodria M, Kil BH, Chatterjee D, Piva SE, Marasa M, Zhang JY, Cocchi E, Caridi G, Gucev Z, Lozanovski VJ, Pisani I, Izzi C, Savoldi G, Gnutti B, Capone VP, Morello W, Guarino S, Esposito P, Lambert S, Radhakrishnan J, Appel GB, Uy NS, Rao MK, Canetta PA, Bomback AS, Nestor JG, Hays T, Cohen DJ, Finale C, Wijk JAEV, La Scola C, Baraldi O, Tondolo F, Di Renzo D, Jamry-Dziurla A, Pezzutto A, Manca V, Mitrotti A, Santoro D, Conti G, Martino M, Giordano M, Gesualdo L, Zibar L, Masnata G, Bonomini M, Alberti D, La Manna G, Caliskan Y, Ranghino A, Marzuillo P, Kiryluk K, Krzemień G, Miklaszewska M, Lin F, Montini G, Scolari F, Fiaccadori E, Arapović A, Saraga M, McKiernan J, Alam S, Zaniew M, Szczepańska M, Szmigielska A, Sikora P, Drożdż D, Mizerska-Wasiak M, Mane S, Lifton RP, Tasic V, Latos-Bielenska A, Gharavi AG, Ghiggeri GM, Materna-Kiryluk A, Westland R, Sanna-Cherchi S
J Am Soc Nephrol 2023 Jun 1;34(6):1105-1119. Epub 2023 Mar 30 doi: 10.1681/ASN.0000000000000132. PMID: 36995132Free PMC Article
Goh AC, Link RE
Urology 2011 Mar;77(3):742-5. doi: 10.1016/j.urology.2010.05.051. PMID: 20801491
Biyani CS, Powell CS
J Endourol 2001 Oct;15(8):797-9. doi: 10.1089/089277901753205771. PMID: 11724117
Walsh G, Dubbins PA
AJR Am J Roentgenol 1996 Oct;167(4):897-900. doi: 10.2214/ajr.167.4.8819378. PMID: 8819378
Lockhart JL, Singer AM, Glenn JF
J Urol 1979 Sep;122(3):310-4. doi: 10.1016/s0022-5347(17)56380-6. PMID: 470000

Clinical prediction guides

Almeida GL, Busato WF, de Cobelli O
Actas Urol Esp 2014 Mar;38(2):127-32. Epub 2013 Aug 1 doi: 10.1016/j.acuro.2013.04.011. PMID: 23910727
Li TR, Du XK, Huo TL
Chin Med Sci J 2011 Jun;26(2):103-8. doi: 10.1016/s1001-9294(11)60028-x. PMID: 21703118
Walsh G, Dubbins PA
AJR Am J Roentgenol 1996 Oct;167(4):897-900. doi: 10.2214/ajr.167.4.8819378. PMID: 8819378
Caione P, Patricolo M, Lais A, Capitanucci ML, Capozza N, Ferro F
Fetal Diagn Ther 1996 May-Jun;11(3):205-9. doi: 10.1159/000264303. PMID: 8739588

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