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Enlarged uterus

MedGen UID:
452126
•Concept ID:
C0151994
•
Finding
Synonyms: Enlarged Uterus; Large uterus; Uterine enlargement
SNOMED CT: Enlarged uterus (198319004); Uterine enlargement (198319004); Large uterus (198319004)
 
HPO: HP:0100878

Definition

An increase in the overall dimensions or volume of the uterus compared to normal. [from NCI]

Professional guidelines

PubMed

Long-term efficacy and safety of levonorgestrel releasing intrauterine system in the treatment of adenomyosis: evidence mapping.
Shi J, Gu Z, Wu Y, Li X, Zhang J, Zhang C, Yan H, Dai Y, Leng J
Arch Gynecol Obstet 2024 Jul;310(1):55-67. Epub 2024 Jun 5 doi: 10.1007/s00404-024-07546-7. PMID: 38836931
Diagnosis and initial management of dysmenorrhea.
Osayande AS, Mehulic S
Am Fam Physician 2014 Mar 1;89(5):341-6. PMID: 24695505
Diagnosis, treatment and need for hysterectomy in management of postcaesarean section vesicouterine fistula.
Ali-El-Dein B, El-Tabey N, El-Hefnawy A, Osman Y, Soliman S, Shaaban AA
Scand J Urol 2014 Oct;48(5):460-5. Epub 2014 Apr 3 doi: 10.3109/21681805.2014.903511. PMID: 24694181

Recent clinical studies

Etiology

Recurrence of Uterine Fibroids After Conservative Surgery or Radiological Procedures: a Narrative Review.
Capezzuoli T, Aslan B, Vannuccini S, Orlandi G, La Torre F, Sorbi F, Fambrini M, Petraglia F
Reprod Sci 2024 May;31(5):1171-1178. Epub 2023 Dec 18 doi: 10.1007/s43032-023-01418-2. PMID: 38110820
Identifying Patterns of Symptom Distress in Pregnant Women: A Pilot Study.
Lee CF, Wen FH, Hsiung Y, Huang JP, Chang CW, Chen HH
Int J Environ Res Public Health 2021 Jun 11;18(12) doi: 10.3390/ijerph18126333. PMID: 34208074Free PMC Article
Characteristics of ovarian endometrioma during pregnancy.
Takami M, Kajiyama R, Miyagi E, Aoki S
J Obstet Gynaecol Res 2021 Sep;47(9):3250-3256. Epub 2021 Jun 21 doi: 10.1111/jog.14862. PMID: 34155737
Reproductive outcomes after hydatiform mole and gestational trophoblastic neoplasia.
Gadducci A, Lanfredini N, Cosio S
Gynecol Endocrinol 2015;31(9):673-8. Epub 2015 Aug 18 doi: 10.3109/09513590.2015.1054803. PMID: 26288335
Impact of myomas on the results of transcervical resection of the endometrium.
Christoffersen C, Kahr HS, Sørensen SS
J Minim Invasive Gynecol 2014 Sep-Oct;21(5):811-7. Epub 2014 Mar 26 doi: 10.1016/j.jmig.2014.03.010. PMID: 24681167

Diagnosis

Clinical practice. Uterine fibroids.
Stewart EA
N Engl J Med 2015 Apr 23;372(17):1646-55. doi: 10.1056/NEJMcp1411029. PMID: 25901428
Diagnosis and initial management of dysmenorrhea.
Osayande AS, Mehulic S
Am Fam Physician 2014 Mar 1;89(5):341-6. PMID: 24695505
The sonographic diagnosis of adenomyosis.
Andreotti RF, Fleischer AC
Ultrasound Q 2005 Sep;21(3):167-70. doi: 10.1097/01.ruq.0000174751.34633.9a. PMID: 16096612
MRI of gynaecological solid masses.
Tanaka YO, Nishida M, Yamaguchi M, Kohno K, Saida Y, Itai Y
Clin Radiol 2000 Dec;55(12):899-911. doi: 10.1053/crad.2000.0600. PMID: 11124069
Adenomyosis.
Siegler AM, Camilien L
J Reprod Med 1994 Nov;39(11):841-53. PMID: 7853271

Therapy

Intravenous infusion route in maternal resuscitation: a scoping review.
Nakamura E, Takahashi S, Matsunaga S, Tanaka H, Furuta M, Sakurai A; Japan Resuscitation Council (JRC), Guideline Editorial Committee
BMC Emerg Med 2021 Dec 3;21(1):151. doi: 10.1186/s12873-021-00546-9. PMID: 34861839Free PMC Article
Reproductive outcomes after hydatiform mole and gestational trophoblastic neoplasia.
Gadducci A, Lanfredini N, Cosio S
Gynecol Endocrinol 2015;31(9):673-8. Epub 2015 Aug 18 doi: 10.3109/09513590.2015.1054803. PMID: 26288335
Clinical practice. Uterine fibroids.
Stewart EA
N Engl J Med 2015 Apr 23;372(17):1646-55. doi: 10.1056/NEJMcp1411029. PMID: 25901428
Diagnosis and initial management of dysmenorrhea.
Osayande AS, Mehulic S
Am Fam Physician 2014 Mar 1;89(5):341-6. PMID: 24695505
Diffusely enlarged uterus: evaluation with MR imaging.
Kido A, Togashi K, Koyama T, Yamaoka T, Fujiwara T, Fujii S
Radiographics 2003 Nov-Dec;23(6):1423-39. doi: 10.1148/rg.236035033. PMID: 14615554

Prognosis

Identifying Patterns of Symptom Distress in Pregnant Women: A Pilot Study.
Lee CF, Wen FH, Hsiung Y, Huang JP, Chang CW, Chen HH
Int J Environ Res Public Health 2021 Jun 11;18(12) doi: 10.3390/ijerph18126333. PMID: 34208074Free PMC Article
Characteristics of ovarian endometrioma during pregnancy.
Takami M, Kajiyama R, Miyagi E, Aoki S
J Obstet Gynaecol Res 2021 Sep;47(9):3250-3256. Epub 2021 Jun 21 doi: 10.1111/jog.14862. PMID: 34155737
Reproductive outcomes after hydatiform mole and gestational trophoblastic neoplasia.
Gadducci A, Lanfredini N, Cosio S
Gynecol Endocrinol 2015;31(9):673-8. Epub 2015 Aug 18 doi: 10.3109/09513590.2015.1054803. PMID: 26288335
Diagnosis and initial management of dysmenorrhea.
Osayande AS, Mehulic S
Am Fam Physician 2014 Mar 1;89(5):341-6. PMID: 24695505
Impact of myomas on the results of transcervical resection of the endometrium.
Christoffersen C, Kahr HS, Sørensen SS
J Minim Invasive Gynecol 2014 Sep-Oct;21(5):811-7. Epub 2014 Mar 26 doi: 10.1016/j.jmig.2014.03.010. PMID: 24681167

Clinical prediction guides

Myoma expulsion after embolization: case report and literature review.
Silva MCA, da Costa REAR, Júnior WOS, Carvalho AP, Vieira SC
Pan Afr Med J 2022;43:210. Epub 2022 Dec 28 doi: 10.11604/pamj.2022.43.210.38030. PMID: 36942141Free PMC Article
Identifying Patterns of Symptom Distress in Pregnant Women: A Pilot Study.
Lee CF, Wen FH, Hsiung Y, Huang JP, Chang CW, Chen HH
Int J Environ Res Public Health 2021 Jun 11;18(12) doi: 10.3390/ijerph18126333. PMID: 34208074Free PMC Article
Characteristics of ovarian endometrioma during pregnancy.
Takami M, Kajiyama R, Miyagi E, Aoki S
J Obstet Gynaecol Res 2021 Sep;47(9):3250-3256. Epub 2021 Jun 21 doi: 10.1111/jog.14862. PMID: 34155737
Impact of myomas on the results of transcervical resection of the endometrium.
Christoffersen C, Kahr HS, Sørensen SS
J Minim Invasive Gynecol 2014 Sep-Oct;21(5):811-7. Epub 2014 Mar 26 doi: 10.1016/j.jmig.2014.03.010. PMID: 24681167
History of adenomyosis.
Benagiano G, Brosens I
Best Pract Res Clin Obstet Gynaecol 2006 Aug;20(4):449-63. Epub 2006 Mar 2 doi: 10.1016/j.bpobgyn.2006.01.007. PMID: 16515887

Recent systematic reviews

A Case Series of Patients with Large Uterine Fibroids and Venous Thromboembolisms.
Cai E, Shao YH, Suarthana E, Bergeron A, Mansour FW, Krishnamurthy S
J Obstet Gynaecol Can 2021 Mar;43(3):352-360. Epub 2020 Nov 5 doi: 10.1016/j.jogc.2020.10.009. PMID: 33303409

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