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Nephrogenic adenoma

MedGen UID:
452429
Concept ID:
C0334039
Neoplastic Process
Synonyms: Nephrogenic Adenoma; nephrogenic adenoma; Nephrogenic Metaplasia; Nephrogenic metaplasia
SNOMED CT: Nephrogenic metaplasia (78236000); Nephrogenic adenoma (78236000)
 
Monarch Initiative: MONDO:0004191

Definition

So-called nephrogenic adenoma is a distinct metaplastic lesion of the urothelium characterized by aggregates of cuboidal or hobnail cells. These cells line thin papillary fronds on the surface or form tubular structures within the lamina propria. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNephrogenic adenoma

Professional guidelines

PubMed

Gordetsky J, Gennaro KH, Selph JP, Rais-Bahrami S
Urology 2016 Sep;95:29-33. Epub 2016 Apr 29 doi: 10.1016/j.urology.2016.04.032. PMID: 27138263
Zhong M, Gersbach E, Rohan SM, Yang XJ
Arch Pathol Lab Med 2013 Mar;137(3):371-81. doi: 10.5858/arpa.2012-0076-RA. PMID: 23451748
Paner GP, Luthringer DJ, Amin MB
Arch Pathol Lab Med 2008 Sep;132(9):1388-96. doi: 10.5858/2008-132-1388-BPIDIP. PMID: 18788849

Recent clinical studies

Etiology

Li L, Williamson SR, Castillo RP, Delma KS, Gonzalgo ML, Epstein JI, Kryvenko ON
Am J Surg Pathol 2023 Jan 1;47(1):37-46. Epub 2022 Nov 4 doi: 10.1097/PAS.0000000000001986. PMID: 36395466
Samaratunga H, Delahunt B, Yaxley J, Egevad L
Pathology 2021 Jan;53(1):44-55. Epub 2020 Oct 15 doi: 10.1016/j.pathol.2020.08.005. PMID: 33070959
Turcan D, Acikalin MF, Yilmaz E, Canaz F, Arik D
Pathol Res Pract 2017 Jul;213(7):831-835. Epub 2017 Mar 25 doi: 10.1016/j.prp.2017.03.001. PMID: 28554748
Gordetsky J, Gennaro KH, Selph JP, Rais-Bahrami S
Urology 2016 Sep;95:29-33. Epub 2016 Apr 29 doi: 10.1016/j.urology.2016.04.032. PMID: 27138263
Porcaro AB, D'Amico A, Ficarra V, Balzarro M, Righetti R, Martignoni G, Cavalleri S, Malossini G
Urol Int 2001;66(3):152-5. doi: 10.1159/000056596. PMID: 11316978

Diagnosis

Kryvenko ON, Wasco MJ, Williamson SR
Arch Pathol Lab Med 2022 May 1;147(5):552-558. doi: 10.5858/arpa.2021-0620-OA. PMID: 35976666
Santi R, Angulo JC, Nesi G, de Petris G, Kuroda N, Hes O, López JI
Pathol Res Pract 2019 Oct;215(10):152561. Epub 2019 Jul 25 doi: 10.1016/j.prp.2019.152561. PMID: 31358481
Kryvenko ON, Epstein JI
Ann Diagn Pathol 2019 Feb;38:11-19. Epub 2018 Sep 26 doi: 10.1016/j.anndiagpath.2018.09.012. PMID: 30380401
Amin W, Parwani AV
Pathol Res Pract 2010 Oct 15;206(10):659-62. Epub 2010 Jul 8 doi: 10.1016/j.prp.2010.06.001. PMID: 20619548
McIntire TL, Soloway MS, Murphy WM
Urology 1987 Mar;29(3):237-41. doi: 10.1016/0090-4295(87)90060-4. PMID: 3548004

Therapy

North D, Jaw J, Hill P, Bateman S, Barraclough N, Langham R
Transplant Proc 2017 Dec;49(10):2381-2383. doi: 10.1016/j.transproceed.2017.09.003. PMID: 29198684
Alexiev BA, Papadimitriou JC, Drachenberg CB
Pathol Res Pract 2015 Sep;211(9):697-701. Epub 2015 Jun 11 doi: 10.1016/j.prp.2015.06.006. PMID: 26189101
Franke EI, Misseri R, Cain MP, Kaefer M, Meldrum KK, Fan R, Rink RC
J Urol 2011 Oct;186(4 Suppl):1586-9. doi: 10.1016/j.juro.2011.04.015. PMID: 21862049
Nakatani T, Kuratsukuri K, Uchida J, Sugimura K, Kuroki Y, Morikawa Y
Hinyokika Kiyo 2002 Jul;48(7):463-6. PMID: 12229190
Fournier G, Menut P, Moal MC, Hardy E, Volant A, Mangin P
J Urol 1996 Jul;156(1):41-4. doi: 10.1016/s0022-5347(01)65932-9. PMID: 8648834

Prognosis

Samaratunga H, Delahunt B, Yaxley J, Egevad L
Pathology 2021 Jan;53(1):44-55. Epub 2020 Oct 15 doi: 10.1016/j.pathol.2020.08.005. PMID: 33070959
Turcan D, Acikalin MF, Yilmaz E, Canaz F, Arik D
Pathol Res Pract 2017 Jul;213(7):831-835. Epub 2017 Mar 25 doi: 10.1016/j.prp.2017.03.001. PMID: 28554748
Venyo AK
Int J Surg Oncol 2015;2015:790235. Epub 2015 Jan 20 doi: 10.1155/2015/790235. PMID: 25685552Free PMC Article
Alexiev BA, LeVea CM
Int J Surg Pathol 2012 Apr;20(2):123-31. Epub 2012 Mar 13 doi: 10.1177/1066896912439095. PMID: 22415059
Amin W, Parwani AV
Pathol Res Pract 2010 Oct 15;206(10):659-62. Epub 2010 Jul 8 doi: 10.1016/j.prp.2010.06.001. PMID: 20619548

Clinical prediction guides

Li L, Williamson SR, Castillo RP, Delma KS, Gonzalgo ML, Epstein JI, Kryvenko ON
Am J Surg Pathol 2023 Jan 1;47(1):37-46. Epub 2022 Nov 4 doi: 10.1097/PAS.0000000000001986. PMID: 36395466
Turcan D, Acikalin MF, Yilmaz E, Canaz F, Arik D
Pathol Res Pract 2017 Jul;213(7):831-835. Epub 2017 Mar 25 doi: 10.1016/j.prp.2017.03.001. PMID: 28554748
López JI, Schiavo-Lena M, Corominas-Cishek A, Yagüe A, Bauleth K, Guarch R, Hes O, Tardanico R
Virchows Arch 2013 Dec;463(6):819-25. Epub 2013 Oct 19 doi: 10.1007/s00428-013-1497-y. PMID: 24142157
Alexiev BA, LeVea CM
Int J Surg Pathol 2012 Apr;20(2):123-31. Epub 2012 Mar 13 doi: 10.1177/1066896912439095. PMID: 22415059
Amin W, Parwani AV
Pathol Res Pract 2010 Oct 15;206(10):659-62. Epub 2010 Jul 8 doi: 10.1016/j.prp.2010.06.001. PMID: 20619548

Recent systematic reviews

Picozzi S, Casellato S, Bozzini G, Ratti D, Macchi A, Rubino B, Pace G, Carmignani L
Urol Oncol 2013 Nov;31(8):1584-90. Epub 2012 Apr 19 doi: 10.1016/j.urolonc.2012.03.009. PMID: 22520573

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