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Amnestic Disorder Due to a General Medical Condition

MedGen UID:
452768
•Concept ID:
C0860625
•
Mental or Behavioral Dysfunction

Definition

A disorder involving memory impairment (either anterograde or retrograde) that is etiologically linked to the direct physiological consequence of a general medical condition. The memory impairment is not the result of a delirium or dementia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmnestic Disorder Due to a General Medical Condition

Recent clinical studies

Etiology

Plasma repressor element 1-silencing transcription factor levels are decreased in patients with Alzheimer's disease.
Wei M, Ni J, Shi J, Li T, Xu X, Li C, Qin B, Fan D, Xie H, Wang Z, Wang Y, Lu T, Tian J
BMC Geriatr 2022 Jun 1;22(1):471. doi: 10.1186/s12877-022-03163-8. PMID: 35650520Free PMC Article
Altered microbiomes distinguish Alzheimer's disease from amnestic mild cognitive impairment and health in a Chinese cohort.
Liu P, Wu L, Peng G, Han Y, Tang R, Ge J, Zhang L, Jia L, Yue S, Zhou K, Li L, Luo B, Wang B
Brain Behav Immun 2019 Aug;80:633-643. Epub 2019 May 4 doi: 10.1016/j.bbi.2019.05.008. PMID: 31063846
Neuropsychological Predictors of Long-Term (10 Years) Mild Cognitive Impairment Stability.
Alves L, Cardoso S, Maroco J, de Mendonça A, Guerreiro M, Silva D
J Alzheimers Dis 2018;62(4):1703-1711. doi: 10.3233/JAD-171034. PMID: 29614683
Substance use disorders and medical comorbidities among high-need, high-risk patients with diabetes.
Wu LT, Ghitza UE, Zhu H, Spratt S, Swartz M, Mannelli P
Drug Alcohol Depend 2018 May 1;186:86-93. Epub 2018 Mar 3 doi: 10.1016/j.drugalcdep.2018.01.008. PMID: 29554592Free PMC Article
A combination of galantamine and memantine modifies cognitive function in subjects with amnestic MCI.
Peters O, Lorenz D, Fesche A, Schmidtke K, Hüll M, Perneczky R, Rüther E, Möller HJ, Jessen F, Maier W, Kornhuber J, Jahn H, Luckhaus C, Gertz HJ, Schröder J, Pantel J, Teipel S, Wellek S, Frölich L, Heuser I
J Nutr Health Aging 2012;16(6):544-8. doi: 10.1007/s12603-012-0062-8. PMID: 22659994

Diagnosis

Plasma repressor element 1-silencing transcription factor levels are decreased in patients with Alzheimer's disease.
Wei M, Ni J, Shi J, Li T, Xu X, Li C, Qin B, Fan D, Xie H, Wang Z, Wang Y, Lu T, Tian J
BMC Geriatr 2022 Jun 1;22(1):471. doi: 10.1186/s12877-022-03163-8. PMID: 35650520Free PMC Article
Alzheimer disease.
Knopman DS, Amieva H, Petersen RC, Chételat G, Holtzman DM, Hyman BT, Nixon RA, Jones DT
Nat Rev Dis Primers 2021 May 13;7(1):33. doi: 10.1038/s41572-021-00269-y. PMID: 33986301Free PMC Article
Early History of Amnesia.
Langer KG
Front Neurol Neurosci 2019;44:64-74. Epub 2019 Apr 30 doi: 10.1159/000494953. PMID: 31220849
Altered microbiomes distinguish Alzheimer's disease from amnestic mild cognitive impairment and health in a Chinese cohort.
Liu P, Wu L, Peng G, Han Y, Tang R, Ge J, Zhang L, Jia L, Yue S, Zhou K, Li L, Luo B, Wang B
Brain Behav Immun 2019 Aug;80:633-643. Epub 2019 May 4 doi: 10.1016/j.bbi.2019.05.008. PMID: 31063846
Neuropsychological Predictors of Long-Term (10 Years) Mild Cognitive Impairment Stability.
Alves L, Cardoso S, Maroco J, de Mendonça A, Guerreiro M, Silva D
J Alzheimers Dis 2018;62(4):1703-1711. doi: 10.3233/JAD-171034. PMID: 29614683

Therapy

Confusion and Hallucination in a Geriatric Patient. Pitfalls of a Rare Differential: Case Report of an Anti-LGI1-Encephalitis.
Meier L, Weinrebe W, Annoni JM, Petersen JA
Clin Interv Aging 2022;17:1423-1432. Epub 2022 Sep 26 doi: 10.2147/CIA.S380316. PMID: 36187571Free PMC Article
MRI-based comparative study of different mild cognitive impairment subtypes: protocol for an observational case-control study.
Yu Y, Zhao W, Li S, Yin C
BMJ Open 2017 Mar 8;7(3):e013432. doi: 10.1136/bmjopen-2016-013432. PMID: 28274963Free PMC Article
Anti-dementia drugs-related changes in gait performance while single and dual tasking in patients with Alzheimer disease: a meta-analysis.
Beauchet O, Launay CP, Montero-Odasso M, Annweiler C, Allali G
Curr Alzheimer Res 2015;12(8):761-71. doi: 10.2174/1567205012666150710111341. PMID: 26159199
A combination of galantamine and memantine modifies cognitive function in subjects with amnestic MCI.
Peters O, Lorenz D, Fesche A, Schmidtke K, Hüll M, Perneczky R, Rüther E, Möller HJ, Jessen F, Maier W, Kornhuber J, Jahn H, Luckhaus C, Gertz HJ, Schröder J, Pantel J, Teipel S, Wellek S, Frölich L, Heuser I
J Nutr Health Aging 2012;16(6):544-8. doi: 10.1007/s12603-012-0062-8. PMID: 22659994

Prognosis

Alzheimer disease.
Knopman DS, Amieva H, Petersen RC, Chételat G, Holtzman DM, Hyman BT, Nixon RA, Jones DT
Nat Rev Dis Primers 2021 May 13;7(1):33. doi: 10.1038/s41572-021-00269-y. PMID: 33986301Free PMC Article
Early History of Amnesia.
Langer KG
Front Neurol Neurosci 2019;44:64-74. Epub 2019 Apr 30 doi: 10.1159/000494953. PMID: 31220849
Altered microbiomes distinguish Alzheimer's disease from amnestic mild cognitive impairment and health in a Chinese cohort.
Liu P, Wu L, Peng G, Han Y, Tang R, Ge J, Zhang L, Jia L, Yue S, Zhou K, Li L, Luo B, Wang B
Brain Behav Immun 2019 Aug;80:633-643. Epub 2019 May 4 doi: 10.1016/j.bbi.2019.05.008. PMID: 31063846
Neuropsychological Predictors of Long-Term (10 Years) Mild Cognitive Impairment Stability.
Alves L, Cardoso S, Maroco J, de Mendonça A, Guerreiro M, Silva D
J Alzheimers Dis 2018;62(4):1703-1711. doi: 10.3233/JAD-171034. PMID: 29614683
Substance use disorders and medical comorbidities among high-need, high-risk patients with diabetes.
Wu LT, Ghitza UE, Zhu H, Spratt S, Swartz M, Mannelli P
Drug Alcohol Depend 2018 May 1;186:86-93. Epub 2018 Mar 3 doi: 10.1016/j.drugalcdep.2018.01.008. PMID: 29554592Free PMC Article

Clinical prediction guides

Plasma repressor element 1-silencing transcription factor levels are decreased in patients with Alzheimer's disease.
Wei M, Ni J, Shi J, Li T, Xu X, Li C, Qin B, Fan D, Xie H, Wang Z, Wang Y, Lu T, Tian J
BMC Geriatr 2022 Jun 1;22(1):471. doi: 10.1186/s12877-022-03163-8. PMID: 35650520Free PMC Article
Altered microbiomes distinguish Alzheimer's disease from amnestic mild cognitive impairment and health in a Chinese cohort.
Liu P, Wu L, Peng G, Han Y, Tang R, Ge J, Zhang L, Jia L, Yue S, Zhou K, Li L, Luo B, Wang B
Brain Behav Immun 2019 Aug;80:633-643. Epub 2019 May 4 doi: 10.1016/j.bbi.2019.05.008. PMID: 31063846
Neuropsychological Predictors of Long-Term (10 Years) Mild Cognitive Impairment Stability.
Alves L, Cardoso S, Maroco J, de Mendonça A, Guerreiro M, Silva D
J Alzheimers Dis 2018;62(4):1703-1711. doi: 10.3233/JAD-171034. PMID: 29614683
Substance use disorders and medical comorbidities among high-need, high-risk patients with diabetes.
Wu LT, Ghitza UE, Zhu H, Spratt S, Swartz M, Mannelli P
Drug Alcohol Depend 2018 May 1;186:86-93. Epub 2018 Mar 3 doi: 10.1016/j.drugalcdep.2018.01.008. PMID: 29554592Free PMC Article
A combination of galantamine and memantine modifies cognitive function in subjects with amnestic MCI.
Peters O, Lorenz D, Fesche A, Schmidtke K, Hüll M, Perneczky R, Rüther E, Möller HJ, Jessen F, Maier W, Kornhuber J, Jahn H, Luckhaus C, Gertz HJ, Schröder J, Pantel J, Teipel S, Wellek S, Frölich L, Heuser I
J Nutr Health Aging 2012;16(6):544-8. doi: 10.1007/s12603-012-0062-8. PMID: 22659994

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