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Inflammatory disease

MedGen UID:
452939
•Concept ID:
C1290884
•
Disease or Syndrome
Synonyms: anatomical structure inflammation; inflammation of anatomical structure; Inflammatory Disease; inflammatory disease; Inflammatory Disorder; Inflammatory disorder; inflammatory disorder
SNOMED CT: Inflammatory disorder (128139000); Inflammatory disease (128139000)
 
Monarch Initiative: MONDO:0021166

Definition

An infectious or non infectious disorder characterized by signs and symptoms derived from focal or extensive tissue infiltration by acute (e.g., polymorphonuclear) or chronic (e.g., lymphocytic-plasmacytic) inflammatory cells. Representative examples of infectious disorders include viral infections, bacterial infections, and parasitic infections. Representative examples of non-infectious inflammatory disorders include inflammatory bowel disease and inflammatory polyps. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInflammatory disease

Professional guidelines

PubMed

Ectopic Pregnancy: Diagnosis and Management.
Hendriks E, Rosenberg R, Prine L
Am Fam Physician 2020 May 15;101(10):599-606. PMID: 32412215
Pelvic Inflammatory Disease: Diagnosis, Management, and Prevention.
Curry A, Williams T, Penny ML
Am Fam Physician 2019 Sep 15;100(6):357-364. PMID: 31524362
Pulmonary arterial hypertension: pathogenesis and clinical management.
Thenappan T, Ormiston ML, Ryan JJ, Archer SL
BMJ 2018 Mar 14;360:j5492. doi: 10.1136/bmj.j5492. PMID: 29540357Free PMC Article

Recent clinical studies

Etiology

Etiology and Diagnosis of Pelvic Inflammatory Disease: Looking Beyond Gonorrhea and Chlamydia.
Mitchell CM, Anyalechi GE, Cohen CR, Haggerty CL, Manhart LE, Hillier SL
J Infect Dis 2021 Aug 16;224(12 Suppl 2):S29-S35. doi: 10.1093/infdis/jiab067. PMID: 34396407Free PMC Article
Bacterial vaginosis and its association with infertility, endometritis, and pelvic inflammatory disease.
Ravel J, Moreno I, Simón C
Am J Obstet Gynecol 2021 Mar;224(3):251-257. Epub 2020 Oct 19 doi: 10.1016/j.ajog.2020.10.019. PMID: 33091407
Pelvic Inflammatory Disease: Diagnosis, Management, and Prevention.
Curry A, Williams T, Penny ML
Am Fam Physician 2019 Sep 15;100(6):357-364. PMID: 31524362
Acute Pelvic Pain.
Dewey K, Wittrock C
Emerg Med Clin North Am 2019 May;37(2):207-218. doi: 10.1016/j.emc.2019.01.012. PMID: 30940367
Pelvic inflammatory disease: current concepts in pathogenesis, diagnosis and treatment.
Mitchell C, Prabhu M
Infect Dis Clin North Am 2013 Dec;27(4):793-809. Epub 2013 Oct 31 doi: 10.1016/j.idc.2013.08.004. PMID: 24275271Free PMC Article

Diagnosis

Pelvic inflammatory disease: diagnosis and treatment in the emergency department.
Taira T, Broussard N, Bugg C
Emerg Med Pract 2022 Dec;24(12):1-24. Epub 2022 Dec 2 PMID: 36378827
Bacterial vaginosis and its association with infertility, endometritis, and pelvic inflammatory disease.
Ravel J, Moreno I, Simón C
Am J Obstet Gynecol 2021 Mar;224(3):251-257. Epub 2020 Oct 19 doi: 10.1016/j.ajog.2020.10.019. PMID: 33091407
Pelvic Inflammatory Disease: Diagnosis, Management, and Prevention.
Curry A, Williams T, Penny ML
Am Fam Physician 2019 Sep 15;100(6):357-364. PMID: 31524362
Pelvic inflammatory disease.
Brunham RC, Gottlieb SL, Paavonen J
N Engl J Med 2015 May 21;372(21):2039-48. doi: 10.1056/NEJMra1411426. PMID: 25992748
Pelvic inflammatory disease: current concepts in pathogenesis, diagnosis and treatment.
Mitchell C, Prabhu M
Infect Dis Clin North Am 2013 Dec;27(4):793-809. Epub 2013 Oct 31 doi: 10.1016/j.idc.2013.08.004. PMID: 24275271Free PMC Article

Therapy

An Update on the Management of Childhood-Onset Systemic Lupus Erythematosus.
Trindade VC, Carneiro-Sampaio M, Bonfa E, Silva CA
Paediatr Drugs 2021 Jul;23(4):331-347. Epub 2021 Jul 10 doi: 10.1007/s40272-021-00457-z. PMID: 34244988Free PMC Article
10 Years of belimumab experience: What have we learnt?
Levy RA, Gonzalez-Rivera T, Khamashta M, Fox NL, Jones-Leone A, Rubin B, Burriss SW, Gairy K, Maurik AV, Roth DA
Lupus 2021 Oct;30(11):1705-1721. Epub 2021 Jul 8 doi: 10.1177/09612033211028653. PMID: 34238087Free PMC Article
Antibiotic therapy for pelvic inflammatory disease.
Savaris RF, Fuhrich DG, Maissiat J, Duarte RV, Ross J
Cochrane Database Syst Rev 2020 Aug 20;8(8):CD010285. doi: 10.1002/14651858.CD010285.pub3. PMID: 32820536Free PMC Article
Ocrelizumab and Other CD20(+) B-Cell-Depleting Therapies in Multiple Sclerosis.
Gelfand JM, Cree BAC, Hauser SL
Neurotherapeutics 2017 Oct;14(4):835-841. doi: 10.1007/s13311-017-0557-4. PMID: 28695471Free PMC Article
Update on the classification and treatment of localized scleroderma.
Bielsa Marsol I
Actas Dermosifiliogr 2013 Oct;104(8):654-66. Epub 2013 Aug 13 doi: 10.1016/j.adengl.2012.10.012. PMID: 23948159

Prognosis

Multisystem inflammatory syndrome (MIS-C): a systematic review and meta-analysis of clinical characteristics, treatment, and outcomes.
Santos MO, Gonçalves LC, Silva PAN, Moreira ALE, Ito CRM, Peixoto FAO, Wastowski IJ, Carneiro LC, Avelino MAG
J Pediatr (Rio J) 2022 Jul-Aug;98(4):338-349. Epub 2021 Dec 3 doi: 10.1016/j.jped.2021.08.006. PMID: 34863701Free PMC Article
The rising incidence of heterotopic pregnancy: Current perspectives and associations with in-vitro fertilization.
Maleki A, Khalid N, Rajesh Patel C, El-Mahdi E
Eur J Obstet Gynecol Reprod Biol 2021 Nov;266:138-144. Epub 2021 Oct 4 doi: 10.1016/j.ejogrb.2021.09.031. PMID: 34653918
A Review of the Challenges and Complexities in the Diagnosis, Etiology, Epidemiology, and Pathogenesis of Pelvic Inflammatory Disease.
Hillier SL, Bernstein KT, Aral S
J Infect Dis 2021 Aug 16;224(12 Suppl 2):S23-S28. doi: 10.1093/infdis/jiab116. PMID: 34396398Free PMC Article
Pneumonia and Streptococcus pneumoniae vaccine.
Kim GL, Seon SH, Rhee DK
Arch Pharm Res 2017 Aug;40(8):885-893. Epub 2017 Jul 22 doi: 10.1007/s12272-017-0933-y. PMID: 28735461Free PMC Article
Gonorrhea: new challenges.
Skerlev M, Čulav-Košćak I
Clin Dermatol 2014 Mar-Apr;32(2):275-81. doi: 10.1016/j.clindermatol.2013.08.010. PMID: 24559563

Clinical prediction guides

Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy: An Expert Consensus Document.
Ammirati E, Frigerio M, Adler ED, Basso C, Birnie DH, Brambatti M, Friedrich MG, Klingel K, Lehtonen J, Moslehi JJ, Pedrotti P, Rimoldi OE, Schultheiss HP, Tschöpe C, Cooper LT Jr, Camici PG
Circ Heart Fail 2020 Nov;13(11):e007405. Epub 2020 Nov 12 doi: 10.1161/CIRCHEARTFAILURE.120.007405. PMID: 33176455Free PMC Article
A Clinician's Guide to Celiac Disease HLA Genetics.
Brown NK, Guandalini S, Semrad C, Kupfer SS
Am J Gastroenterol 2019 Oct;114(10):1587-1592. doi: 10.14309/ajg.0000000000000310. PMID: 31274511
Measuring hand grip strength in rheumatoid arthritis.
Higgins SC, Adams J, Hughes R
Rheumatol Int 2018 May;38(5):707-714. Epub 2018 Apr 6 doi: 10.1007/s00296-018-4024-2. PMID: 29626222
Update on Lupus Nephritis.
Almaani S, Meara A, Rovin BH
Clin J Am Soc Nephrol 2017 May 8;12(5):825-835. Epub 2016 Nov 7 doi: 10.2215/CJN.05780616. PMID: 27821390Free PMC Article
Myocarditis.
Fung G, Luo H, Qiu Y, Yang D, McManus B
Circ Res 2016 Feb 5;118(3):496-514. doi: 10.1161/CIRCRESAHA.115.306573. PMID: 26846643

Recent systematic reviews

Diet and Systemic Lupus Erythematosus (SLE): From Supplementation to Intervention.
Jiao H, Acar G, Robinson GA, Ciurtin C, Jury EC, Kalea AZ
Int J Environ Res Public Health 2022 Sep 20;19(19) doi: 10.3390/ijerph191911895. PMID: 36231195Free PMC Article
Multisystem inflammatory syndrome (MIS-C): a systematic review and meta-analysis of clinical characteristics, treatment, and outcomes.
Santos MO, Gonçalves LC, Silva PAN, Moreira ALE, Ito CRM, Peixoto FAO, Wastowski IJ, Carneiro LC, Avelino MAG
J Pediatr (Rio J) 2022 Jul-Aug;98(4):338-349. Epub 2021 Dec 3 doi: 10.1016/j.jped.2021.08.006. PMID: 34863701Free PMC Article
Multisystem inflammatory syndrome in children related to COVID-19: a systematic review.
Hoste L, Van Paemel R, Haerynck F
Eur J Pediatr 2021 Jul;180(7):2019-2034. Epub 2021 Feb 18 doi: 10.1007/s00431-021-03993-5. PMID: 33599835Free PMC Article
Systematic Review of Safety and Efficacy of Rituximab in Treating Immune-Mediated Disorders.
Kaegi C, Wuest B, Schreiner J, Steiner UC, Vultaggio A, Matucci A, Crowley C, Boyman O
Front Immunol 2019;10:1990. Epub 2019 Sep 6 doi: 10.3389/fimmu.2019.01990. PMID: 31555262Free PMC Article
Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation.
Irwin MR, Olmstead R, Carroll JE
Biol Psychiatry 2016 Jul 1;80(1):40-52. Epub 2015 Jun 1 doi: 10.1016/j.biopsych.2015.05.014. PMID: 26140821Free PMC Article

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