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Paranoid personality disorder

MedGen UID:
45321
•Concept ID:
C0030477
•
Mental or Behavioral Dysfunction
Synonyms: Disorder, Paranoid Personality; Disorders, Paranoid Personality; Paranoid Personalities; Paranoid Personality; Paranoid Personality Disorder; Paranoid Personality Disorders; Personalities, Paranoid; Personality Disorder, Paranoid; Personality Disorders, Paranoid; Personality, Paranoid
SNOMED CT: Paranoid personality disorder (13601005)
 
Monarch Initiative: MONDO:0001163

Definition

A disorder characterized by an enduring pattern of behavior based on the pervasive belief that the motives of others are malevolent and that they should not be trusted. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParanoid personality disorder

Professional guidelines

PubMed

First treatment contact for ADHD: predictors of and gender differences in treatment seeking.
Dakwar E, Levin FR, Olfson M, Wang S, Kerridge B, Blanco C
Psychiatr Serv 2014 Dec 1;65(12):1465-73. Epub 2014 Oct 31 doi: 10.1176/appi.ps.201300298. PMID: 25081894Free PMC Article
Psychopharmacological treatment and course in paranoid personality disorder: a case series.
Birkeland SF
Int Clin Psychopharmacol 2013 Sep;28(5):283-5. doi: 10.1097/YIC.0b013e328363f676. PMID: 23820335
Gender bias in diagnostic criteria for personality disorders: an item response theory analysis.
Jane JS, Oltmanns TF, South SC, Turkheimer E
J Abnorm Psychol 2007 Feb;116(1):166-75. doi: 10.1037/0021-843X.116.1.166. PMID: 17324027Free PMC Article

Recent clinical studies

Etiology

Interpersonal sensitivity, bullying victimization and paranoid ideation among help-seeking adolescents and young adults.
Masillo A, Valmaggia LR, Saba R, Brandizzi M, Lo Cascio N, Telesforo L, Venturini P, Izzo A, Mattioli MT, D'Alema M, Girardi P, Fiori Nastro P
Early Interv Psychiatry 2019 Feb;13(1):57-63. Epub 2017 May 30 doi: 10.1111/eip.12447. PMID: 28560857
Paranoid personality disorder.
Triebwasser J, Chemerinski E, Roussos P, Siever LJ
J Pers Disord 2013 Dec;27(6):795-805. Epub 2012 Aug 28 doi: 10.1521/pedi_2012_26_055. PMID: 22928850
A comparative study of paranoid and schizoid personality disorders.
Fulton M, Winokur G
Am J Psychiatry 1993 Sep;150(9):1363-7. doi: 10.1176/ajp.150.9.1363. PMID: 8352347
Schizotypal and paranoid personality disorder in the relatives of patients with schizophrenia and affective disorders: a review.
Webb CT, Levinson DF
Schizophr Res 1993 Dec;11(1):81-92. doi: 10.1016/0920-9964(93)90041-g. PMID: 8297808
Delusional (paranoid) disorders.
Munro A
Can J Psychiatry 1988 Jun;33(5):399-404. doi: 10.1177/070674378803300516. PMID: 3044569

Diagnosis

Conceptualizing a less paranoid schizophrenia.
Long J, Hull R
Philos Ethics Humanit Med 2023 Nov 8;18(1):14. doi: 10.1186/s13010-023-00142-8. PMID: 37936219Free PMC Article
Paranoid personality disorder.
Triebwasser J, Chemerinski E, Roussos P, Siever LJ
J Pers Disord 2013 Dec;27(6):795-805. Epub 2012 Aug 28 doi: 10.1521/pedi_2012_26_055. PMID: 22928850
A comparative study of paranoid and schizoid personality disorders.
Fulton M, Winokur G
Am J Psychiatry 1993 Sep;150(9):1363-7. doi: 10.1176/ajp.150.9.1363. PMID: 8352347
Paranoid personality disorder: a synthesis of developmental, dynamic, and descriptive features.
Akhtar S
Am J Psychother 1990 Jan;44(1):5-25. doi: 10.1176/appi.psychotherapy.1990.44.1.5. PMID: 2183636
Delusional (paranoid) disorders.
Munro A
Can J Psychiatry 1988 Jun;33(5):399-404. doi: 10.1177/070674378803300516. PMID: 3044569

Therapy

Paranoid personality disorder in the United States: the role of race, illicit drug use, and income.
Raza GT, DeMarce JM, Lash SJ, Parker JD
J Ethn Subst Abuse 2014;13(3):247-57. doi: 10.1080/15332640.2013.850463. PMID: 25176118
Paranoid personality disorder and the schizophrenia spectrum-Where to draw the line?
Birkeland SF
Personal Ment Health 2013 Aug;7(3):254-8. doi: 10.1002/pmh.1244. PMID: 24343968
Psychopharmacological treatment and course in paranoid personality disorder: a case series.
Birkeland SF
Int Clin Psychopharmacol 2013 Sep;28(5):283-5. doi: 10.1097/YIC.0b013e328363f676. PMID: 23820335
Assumptions in borderline personality disorder: specificity, stability and relationship with etiological factors.
Arntz A, Dietzel R, Dreessen L
Behav Res Ther 1999 Jun;37(6):545-57. doi: 10.1016/s0005-7967(98)00152-1. PMID: 10372468
Querulous behavior.
Ungvari GS, Pang AH, Wong CK
Med Sci Law 1997 Jul;37(3):265-70. doi: 10.1177/002580249703700315. PMID: 9264237

Prognosis

Conceptualizing a less paranoid schizophrenia.
Long J, Hull R
Philos Ethics Humanit Med 2023 Nov 8;18(1):14. doi: 10.1186/s13010-023-00142-8. PMID: 37936219Free PMC Article
Parents' Personality Disorders as Predictor of Substance Use Disorder in Children and Adolescents.
Mohammadi MR, Hojjat SK, Mostafavi SA, Khaleghi A, Hooshyari Z, Ahmadi N, Kaviyani F, Norozi Khalili M
Arch Iran Med 2021 Jun 1;24(6):478-486. doi: 10.34172/aim.2021.69. PMID: 34488311
Interpersonal sensitivity, bullying victimization and paranoid ideation among help-seeking adolescents and young adults.
Masillo A, Valmaggia LR, Saba R, Brandizzi M, Lo Cascio N, Telesforo L, Venturini P, Izzo A, Mattioli MT, D'Alema M, Girardi P, Fiori Nastro P
Early Interv Psychiatry 2019 Feb;13(1):57-63. Epub 2017 May 30 doi: 10.1111/eip.12447. PMID: 28560857
Vocational functioning in schizotypal and paranoid personality disorders.
McGurk SR, Mueser KT, Mischel R, Adams R, Harvey PD, McClure MM, Look AE, Leung WW, Siever LJ
Psychiatry Res 2013 Dec 15;210(2):498-504. Epub 2013 Aug 8 doi: 10.1016/j.psychres.2013.06.019. PMID: 23932840
A comparative study of paranoid and schizoid personality disorders.
Fulton M, Winokur G
Am J Psychiatry 1993 Sep;150(9):1363-7. doi: 10.1176/ajp.150.9.1363. PMID: 8352347

Clinical prediction guides

Relationship of DRD5 and MAO-B VNTR polymorphisms with paranoid and antisocial personality disorders in polydrug users.
O'Higgins M, Benito A, Real-López M, Gil-Miravet I, Ochoa E, Haro G
Personal Ment Health 2023 Feb;17(1):77-86. Epub 2022 Aug 12 doi: 10.1002/pmh.1563. PMID: 35961947
Parents' Personality Disorders as Predictor of Substance Use Disorder in Children and Adolescents.
Mohammadi MR, Hojjat SK, Mostafavi SA, Khaleghi A, Hooshyari Z, Ahmadi N, Kaviyani F, Norozi Khalili M
Arch Iran Med 2021 Jun 1;24(6):478-486. doi: 10.34172/aim.2021.69. PMID: 34488311
Interpersonal sensitivity, bullying victimization and paranoid ideation among help-seeking adolescents and young adults.
Masillo A, Valmaggia LR, Saba R, Brandizzi M, Lo Cascio N, Telesforo L, Venturini P, Izzo A, Mattioli MT, D'Alema M, Girardi P, Fiori Nastro P
Early Interv Psychiatry 2019 Feb;13(1):57-63. Epub 2017 May 30 doi: 10.1111/eip.12447. PMID: 28560857
Dependent and paranoid personality patterns in myotonic dystrophy type 1.
Peric S, Sreckov M, Basta I, Lavrnic D, Vujnic M, Marjanovic I, Rakocevic Stojanovic V
Acta Neurol Scand 2014 Apr;129(4):219-25. Epub 2013 Sep 3 doi: 10.1111/ane.12173. PMID: 24032453
Vocational functioning in schizotypal and paranoid personality disorders.
McGurk SR, Mueser KT, Mischel R, Adams R, Harvey PD, McClure MM, Look AE, Leung WW, Siever LJ
Psychiatry Res 2013 Dec 15;210(2):498-504. Epub 2013 Aug 8 doi: 10.1016/j.psychres.2013.06.019. PMID: 23932840

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