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Pancreatic vasoactive intestinal peptide producing tumor

MedGen UID:: 453212
•Concept ID:: C2033037
•: Neoplastic Process

Synonyms:	Pancreatic Vasoactive Intestinal Peptide Producing Neoplasm; pancreatic vasoactive intestinal peptide producing neoplasm; Pancreatic Vasoactive Intestinal Peptide Producing Tumor; pancreatic vasoactive intestinal peptide producing tumor; Pancreatic VIP Producing Neoplasm; pancreatic VIP producing neoplasm; Pancreatic VIP Producing NET; pancreatic VIP producing NET; Pancreatic VIP Producing Tumor; pancreatic VIP producing tumor; pancreatic VIP producing tumour; Pancreatic VIP-Producing Neuroendocrine Tumor; pancreatic VIP-producing neuroendocrine tumor; pancreatic VIP-producing neuroendocrine tumour; Pancreatic Vipoma

Monarch Initiative:	MONDO:0003622

Definition

A usually malignant pancreatic neuroendocrine tumor producing vasoactive intestinal peptide (VIP). It is associated with watery diarrhea, hypokalemia, and hypochlorhydria or achlorhydria. One third of cases are metastatic at the time of diagnosis. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVPancreatic vasoactive intestinal peptide producing tumor

Disease
- Disorder by Site
  - Disorder of endocrine system
    - Neoplasm of the endocrine system
      - Functioning endocrine neoplasm
        Functional pancreatic neuroendocrine tumor
        Pancreatic vasoactive intestinal peptide producing tumor
        Malignant Pancreatic Vipoma

Professional guidelines

PubMed

Pancreatic neuroendocrine tumors: clinical features, diagnosis and medical treatment: advances.

Ito T, Igarashi H, Jensen RT
Best Pract Res Clin Gastroenterol 2012 Dec;26(6):737-53. doi: 10.1016/j.bpg.2012.12.003. PMID: 23582916 Free PMC Article

The surgical and systemic management of neuroendocrine tumors of the pancreas.

Abood GJ, Go A, Malhotra D, Shoup M
Surg Clin North Am 2009 Feb;89(1):249-66, x. doi: 10.1016/j.suc.2008.10.001. PMID: 19186239

Somatostatin and analogues in the treatment of VIPoma.

O'Dorisio TM, Gaginella TS, Mekhjian HS, Rao B, O'Dorisio MS
Ann N Y Acad Sci 1988;527:528-35. doi: 10.1111/j.1749-6632.1988.tb27006.x. PMID: 2898913

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Clinical resources

ClinicalTrials.gov

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Reviews

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Pancreatic vasoactive intestinal peptide producing tumor
Pancreatic vasoactive intestinal peptide producing tumor

MedGen
Pancreatic somatostatinoma
Pancreatic somatostatinoma

MedGen
arrd-19 Arrestin C-terminal-like domain-containing protein [Caenorhabditis elega...
arrd-19 Arrestin C-terminal-like domain-containing protein [Caenorhabditis elegans]
Gene ID:178764

Gene

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