U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Intra-Abdominal Hypertension

MedGen UID:
453249
•Concept ID:
C2242710
•
Disease or Syndrome
Synonyms: Hypertension, Intra-Abdominal; Hypertension, Intraabdominal; Hypertensions, Intra-Abdominal; Hypertensions, Intraabdominal; Intra Abdominal Hypertension; Intra-Abdominal Hypertensions; Intraabdominal Hypertension; Intraabdominal Hypertensions

Definition

Pathological elevation of intra-abdominal pressure (>12 mm Hg). It may develop as a result of SEPSIS; PANCREATITIS; capillary leaks, burns, or surgery. When the pressure is higher than 20 mm Hg, often with end-organ dysfunction, it is referred to as abdominal compartment syndrome. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntra-Abdominal Hypertension

Professional guidelines

PubMed

Management of the patient with the open abdomen.
Einav S, Zimmerman FS, Tankel J, Leone M
Curr Opin Crit Care 2021 Dec 1;27(6):726-732. doi: 10.1097/MCC.0000000000000879. PMID: 34561356
Abdominal compartment syndrome: Current concepts and management.
Montalvo-Jave EE, Espejel-Deloiza M, Chernitzky-Camaño J, Peña-Pérez CA, Rivero-Sigarroa E, Ortega-León LH
Rev Gastroenterol Mex (Engl Ed) 2020 Oct-Dec;85(4):443-451. Epub 2020 Aug 23 doi: 10.1016/j.rgmx.2020.03.003. PMID: 32847726
Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome.
Kirkpatrick AW, Roberts DJ, De Waele J, Jaeschke R, Malbrain ML, De Keulenaer B, Duchesne J, Bjorck M, Leppaniemi A, Ejike JC, Sugrue M, Cheatham M, Ivatury R, Ball CG, Reintam Blaser A, Regli A, Balogh ZJ, D'Amours S, Debergh D, Kaplan M, Kimball E, Olvera C; Pediatric Guidelines Sub-Committee for the World Society of the Abdominal Compartment Syndrome
Intensive Care Med 2013 Jul;39(7):1190-206. Epub 2013 May 15 doi: 10.1007/s00134-013-2906-z. PMID: 23673399Free PMC Article

Recent clinical studies

Etiology

Fluid management in acute kidney injury: from evaluating fluid responsiveness towards assessment of fluid tolerance.
Argaiz ER, Rola P, Haycock KH, Verbrugge FH
Eur Heart J Acute Cardiovasc Care 2022 Nov 2;11(10):786-793. doi: 10.1093/ehjacc/zuac104. PMID: 36069621
Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis.
He W, Chen P, Lei Y, Xia L, Liu P, Zhu Y, Zeng H, Wu Y, Ke H, Huang X, Cai W, Sun X, Huang W, Sutton R, Zhu Y, Lu N
Crit Care 2022 Mar 3;26(1):52. doi: 10.1186/s13054-022-03922-4. PMID: 35241135Free PMC Article
Management of the patient with the open abdomen.
Einav S, Zimmerman FS, Tankel J, Leone M
Curr Opin Crit Care 2021 Dec 1;27(6):726-732. doi: 10.1097/MCC.0000000000000879. PMID: 34561356
Abdominal compartment syndrome.
Sosa G, Gandham N, Landeras V, Calimag AP, Lerma E
Dis Mon 2019 Jan;65(1):5-19. Epub 2018 Nov 17 doi: 10.1016/j.disamonth.2018.04.003. PMID: 30454823
Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome.
Kirkpatrick AW, Roberts DJ, De Waele J, Jaeschke R, Malbrain ML, De Keulenaer B, Duchesne J, Bjorck M, Leppaniemi A, Ejike JC, Sugrue M, Cheatham M, Ivatury R, Ball CG, Reintam Blaser A, Regli A, Balogh ZJ, D'Amours S, Debergh D, Kaplan M, Kimball E, Olvera C; Pediatric Guidelines Sub-Committee for the World Society of the Abdominal Compartment Syndrome
Intensive Care Med 2013 Jul;39(7):1190-206. Epub 2013 May 15 doi: 10.1007/s00134-013-2906-z. PMID: 23673399Free PMC Article

Diagnosis

Intra-abdominal hypertension and abdominal compartment syndrome.
De Waele JJ
Curr Opin Crit Care 2022 Dec 1;28(6):695-701. Epub 2022 Oct 3 doi: 10.1097/MCC.0000000000000991. PMID: 36194128
Acute Kidney Injury in Patients with Liver Disease.
Cullaro G, Kanduri SR, Velez JCQ
Clin J Am Soc Nephrol 2022 Nov;17(11):1674-1684. Epub 2022 Jul 28 doi: 10.2215/CJN.03040322. PMID: 35902128Free PMC Article
Congestive nephropathy: a neglected entity? Proposal for diagnostic criteria and future perspectives.
Husain-Syed F, Gröne HJ, Assmus B, Bauer P, Gall H, Seeger W, Ghofrani A, Ronco C, Birk HW
ESC Heart Fail 2021 Feb;8(1):183-203. Epub 2020 Nov 30 doi: 10.1002/ehf2.13118. PMID: 33258308Free PMC Article
Abdominal compartment syndrome: Current concepts and management.
Montalvo-Jave EE, Espejel-Deloiza M, Chernitzky-Camaño J, Peña-Pérez CA, Rivero-Sigarroa E, Ortega-León LH
Rev Gastroenterol Mex (Engl Ed) 2020 Oct-Dec;85(4):443-451. Epub 2020 Aug 23 doi: 10.1016/j.rgmx.2020.03.003. PMID: 32847726
Abdominal compartment syndrome.
Sosa G, Gandham N, Landeras V, Calimag AP, Lerma E
Dis Mon 2019 Jan;65(1):5-19. Epub 2018 Nov 17 doi: 10.1016/j.disamonth.2018.04.003. PMID: 30454823

Therapy

Physiological and Pathophysiological Consequences of Mechanical Ventilation.
Silva PL, Ball L, Rocco PRM, Pelosi P
Semin Respir Crit Care Med 2022 Jun;43(3):321-334. Epub 2022 Apr 19 doi: 10.1055/s-0042-1744447. PMID: 35439832
Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis.
He W, Chen P, Lei Y, Xia L, Liu P, Zhu Y, Zeng H, Wu Y, Ke H, Huang X, Cai W, Sun X, Huang W, Sutton R, Zhu Y, Lu N
Crit Care 2022 Mar 3;26(1):52. doi: 10.1186/s13054-022-03922-4. PMID: 35241135Free PMC Article
Management of the patient with the open abdomen.
Einav S, Zimmerman FS, Tankel J, Leone M
Curr Opin Crit Care 2021 Dec 1;27(6):726-732. doi: 10.1097/MCC.0000000000000879. PMID: 34561356
The open abdomen in trauma and non-trauma patients: WSES guidelines.
Coccolini F, Roberts D, Ansaloni L, Ivatury R, Gamberini E, Kluger Y, Moore EE, Coimbra R, Kirkpatrick AW, Pereira BM, Montori G, Ceresoli M, Abu-Zidan FM, Sartelli M, Velmahos G, Fraga GP, Leppaniemi A, Tolonen M, Galante J, Razek T, Maier R, Bala M, Sakakushev B, Khokha V, Malbrain M, Agnoletti V, Peitzman A, Demetrashvili Z, Sugrue M, Di Saverio S, Martzi I, Soreide K, Biffl W, Ferrada P, Parry N, Montravers P, Melotti RM, Salvetti F, Valetti TM, Scalea T, Chiara O, Cimbanassi S, Kashuk JL, Larrea M, Hernandez JAM, Lin HF, Chirica M, Arvieux C, Bing C, Horer T, De Simone B, Masiakos P, Reva V, DeAngelis N, Kike K, Balogh ZJ, Fugazzola P, Tomasoni M, Latifi R, Naidoo N, Weber D, Handolin L, Inaba K, Hecker A, Kuo-Ching Y, Ordoñez CA, Rizoli S, Gomes CA, De Moya M, Wani I, Mefire AC, Boffard K, Napolitano L, Catena F
World J Emerg Surg 2018;13:7. Epub 2018 Feb 2 doi: 10.1186/s13017-018-0167-4. PMID: 29434652Free PMC Article
Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients: a systematic review with suggestions for clinical practice.
Malbrain ML, Marik PE, Witters I, Cordemans C, Kirkpatrick AW, Roberts DJ, Van Regenmortel N
Anaesthesiol Intensive Ther 2014 Nov-Dec;46(5):361-80. doi: 10.5603/AIT.2014.0060. PMID: 25432556

Prognosis

Management of the patient with the open abdomen.
Einav S, Zimmerman FS, Tankel J, Leone M
Curr Opin Crit Care 2021 Dec 1;27(6):726-732. doi: 10.1097/MCC.0000000000000879. PMID: 34561356
Intra-abdominal hypertension and abdominal compartment syndrome: a current review.
Kimball EJ
Curr Opin Crit Care 2021 Apr 1;27(2):164-168. doi: 10.1097/MCC.0000000000000797. PMID: 33480617
Management of peripartum intra-abdominal hypertension and abdominal compartment syndrome.
Lozada MJ, Goyal V, Levin D, Walden RL, Osmundson SS, Pacheco LD, Malbrain MLNG
Acta Obstet Gynecol Scand 2019 Nov;98(11):1386-1397. Epub 2019 Jun 18 doi: 10.1111/aogs.13638. PMID: 31070780Free PMC Article
Abdominal Compliance and Laparoscopy: A Review.
Ott DE
JSLS 2019 Jan-Mar;23(1) doi: 10.4293/JSLS.2018.00080. PMID: 30828242Free PMC Article
Intra-abdominal hypertension and abdominal compartment syndrome in pediatrics. A review.
Thabet FC, Ejike JC
J Crit Care 2017 Oct;41:275-282. Epub 2017 Jun 7 doi: 10.1016/j.jcrc.2017.06.004. PMID: 28614762

Clinical prediction guides

Intra-Abdominal Hypertension: A Systemic Complication of Severe Acute Pancreatitis.
Mancilla Asencio C, Berger Fleiszig Z
Medicina (Kaunas) 2022 Jun 10;58(6) doi: 10.3390/medicina58060785. PMID: 35744049Free PMC Article
Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis.
He W, Chen P, Lei Y, Xia L, Liu P, Zhu Y, Zeng H, Wu Y, Ke H, Huang X, Cai W, Sun X, Huang W, Sutton R, Zhu Y, Lu N
Crit Care 2022 Mar 3;26(1):52. doi: 10.1186/s13054-022-03922-4. PMID: 35241135Free PMC Article
Abdominal Compliance and Laparoscopy: A Review.
Ott DE
JSLS 2019 Jan-Mar;23(1) doi: 10.4293/JSLS.2018.00080. PMID: 30828242Free PMC Article
Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients: a systematic review with suggestions for clinical practice.
Malbrain ML, Marik PE, Witters I, Cordemans C, Kirkpatrick AW, Roberts DJ, Van Regenmortel N
Anaesthesiol Intensive Ther 2014 Nov-Dec;46(5):361-80. doi: 10.5603/AIT.2014.0060. PMID: 25432556
Abdominal compartment syndrome.
Mayer D, Veith FJ, Lachat M, Pfammatter T, Hechelhammer L, Rancic Z
Minerva Chir 2010 Jun;65(3):329-46. PMID: 20668421

Recent systematic reviews

Intra-abdominal hypertension and increased acute kidney injury risk: a systematic review and meta-analysis.
Sun J, Sun H, Sun Z, Yang X, Zhou S, Wei J
J Int Med Res 2021 May;49(5):3000605211016627. doi: 10.1177/03000605211016627. PMID: 34053324Free PMC Article
Incidence of Intra-Abdominal Hypertension and Abdominal Compartment Syndrome: A Systematic Review.
Khot Z, Murphy PB, Sela N, Parry NG, Vogt K, Ball IM
J Intensive Care Med 2021 Feb;36(2):197-202. Epub 2019 Dec 6 doi: 10.1177/0885066619892225. PMID: 31808368
Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine.
Reintam Blaser A, Preiser JC, Fruhwald S, Wilmer A, Wernerman J, Benstoem C, Casaer MP, Starkopf J, van Zanten A, Rooyackers O, Jakob SM, Loudet CI, Bear DE, Elke G, Kott M, Lautenschläger I, Schäper J, Gunst J, Stoppe C, Nobile L, Fuhrmann V, Berger MM, Oudemans-van Straaten HM, Arabi YM, Deane AM; Working Group on Gastrointestinal Function within the Section of Metabolism, Endocrinology and Nutrition (MEN Section) of ESICM
Crit Care 2020 May 15;24(1):224. doi: 10.1186/s13054-020-02889-4. PMID: 32414423Free PMC Article
Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients: a systematic review with suggestions for clinical practice.
Malbrain ML, Marik PE, Witters I, Cordemans C, Kirkpatrick AW, Roberts DJ, Van Regenmortel N
Anaesthesiol Intensive Ther 2014 Nov-Dec;46(5):361-80. doi: 10.5603/AIT.2014.0060. PMID: 25432556
A systematic review on intra-abdominal pressure in severely burned patients.
Strang SG, Van Lieshout EM, Breederveld RS, Van Waes OJ
Burns 2014 Feb;40(1):9-16. Epub 2013 Sep 17 doi: 10.1016/j.burns.2013.07.001. PMID: 24050978

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...