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Radiation-Related Sarcoma

MedGen UID:
457674
•Concept ID:
C2985448
•
Neoplastic Process

Definition

A sarcoma that arises in the bones or soft tissues following exposure to ionizing or non-ionizing radiation. [from NCI]

Professional guidelines

PubMed

Radiation-Related New Primary Solid Cancers in the Childhood Cancer Survivor Study: Comparative Radiation Dose Response and Modification of Treatment Effects.
Inskip PD, Sigurdson AJ, Veiga L, Bhatti P, Ronckers C, Rajaraman P, Boukheris H, Stovall M, Smith S, Hammond S, Henderson TO, Watt TC, Mertens AC, Leisenring W, Stratton K, Whitton J, Donaldson SS, Armstrong GT, Robison LL, Neglia JP
Int J Radiat Oncol Biol Phys 2016 Mar 15;94(4):800-7. Epub 2015 Dec 15 doi: 10.1016/j.ijrobp.2015.11.046. PMID: 26972653Free PMC Article
Retroperitoneal soft tissue sarcoma: an analysis of radiation and surgical treatment.
Ballo MT, Zagars GK, Pollock RE, Benjamin RS, Feig BW, Cormier JN, Hunt KK, Patel SR, Trent JC, Beddar S, Pisters PW
Int J Radiat Oncol Biol Phys 2007 Jan 1;67(1):158-63. Epub 2006 Nov 2 doi: 10.1016/j.ijrobp.2006.08.025. PMID: 17084545
Outcome of radiation-related osteosarcoma after treatment of childhood and adolescent cancer: a study of 23 cases.
Tabone MD, Terrier P, Pacquement H, Brunat-Mentigny M, Schmitt C, Babin-Boilletot A, Mahmoud HH, Kalifa C
J Clin Oncol 1999 Sep;17(9):2789-95. doi: 10.1200/JCO.1999.17.9.2789. PMID: 10561354

Recent clinical studies

Diagnosis

Postirradiation soft tissue sarcoma occurring in breast cancer patients: report of seven cases and results of combination chemotherapy.
Kuten A, Sapir D, Cohen Y, Haim N, Borovik R, Robinson E
J Surg Oncol 1985 Mar;28(3):168-71. doi: 10.1002/jso.2930280304. PMID: 3838353

Therapy

Unusual Presentation of Postradiation Sarcoma With Subsequent Intestinal Metastasis Revealed by 18F-FDG PET/CT.
Lee TH, Chang CP, Wu YH, Huang WS
Clin Nucl Med 2017 Oct;42(10):e438-e440. doi: 10.1097/RLU.0000000000001779. PMID: 28759523
Postirradiation soft tissue sarcoma occurring in breast cancer patients: report of seven cases and results of combination chemotherapy.
Kuten A, Sapir D, Cohen Y, Haim N, Borovik R, Robinson E
J Surg Oncol 1985 Mar;28(3):168-71. doi: 10.1002/jso.2930280304. PMID: 3838353

Supplemental Content

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