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Plummer-Vinson syndrome

MedGen UID:
45967
•Concept ID:
C0032249
•
Disease or Syndrome
Synonyms: Dysphagia sideropenica; Kelly's syndrome; Paterson's syndrome; Paterson-Brown-Kelly syndrome; Paterson-Kelly syndrome
SNOMED CT: Brown-Kelly-Paterson syndrome (80126007); Plummer-Vinson-Patterson-Kelly syndrome (80126007); Plummer-Vinson syndrome (80126007); Paterson-Kelly syndrome (80126007); Sideropenic dysphagia (80126007)
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
•Concept ID:
CN307042
•
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
See: This record
Unknown inheritance (Orphanet)
 
Monarch Initiative: MONDO:0018895
Orphanet: ORPHA54028

Definition

Plummer-Vinson or Paterson-Kelly syndrome presents as a classical triad of dysphagia, iron-deficiency anemia and esophageal webs. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPlummer-Vinson syndrome
Follow this link to review classifications for Plummer-Vinson syndrome in Orphanet.

Professional guidelines

PubMed

Koilonychia: an update on pathophysiology, differential diagnosis and clinical relevance.
Walker J, Baran R, Vélez N, Jellinek N
J Eur Acad Dermatol Venereol 2016 Nov;30(11):1985-1991. Epub 2016 Aug 17 doi: 10.1111/jdv.13610. PMID: 27531645
Screening diagnosis and staging of esophageal cancer.
Lightdale CJ, Winawer SJ
Semin Oncol 1984 Jun;11(2):101-12. PMID: 6729490

Recent clinical studies

Etiology

Plummer-Vinson Syndrome: A Rare Cause of Dysphagia in an Octogenarian.
Harmouch F, Liaquat H, Chaput KJ, Geme B
Am J Case Rep 2021 Apr 24;22:e929899. doi: 10.12659/AJCR.929899. PMID: 33895769Free PMC Article
Plummer-Vinson syndrome: A decade's experience of 132 cases from a single center.
Patil M, Malipatel R, Devarbhavi H
J Gastroenterol Hepatol 2021 Jan;36(1):181-185. Epub 2020 Jun 29 doi: 10.1111/jgh.15139. PMID: 32525241
PLUMMER VINSON SYNDROME--is it common in males?
Bakshi SS
Arq Gastroenterol 2015 Jul-Sep;52(3):250-2. doi: 10.1590/S0004-28032015000300018. PMID: 26486296
Plummer-Vinson syndrome.
Hefaiedh R, Boutreaa Y, Ouakaa-Kchaou A, Gargouri D, Elloumi H, Kochlef A, Romani M, Kilani A, Kharrat J, Ghorbel A
Tunis Med 2010 Oct;88(10):721-4. PMID: 20890819
Plummer-Vinson syndrome.
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article

Diagnosis

Plummer-Vinson syndrome in primary Sjögren syndrome: a case-based review.
de Carvalho JF, Lerner A
Immunol Res 2022 Feb;70(1):19-22. Epub 2021 Oct 14 doi: 10.1007/s12026-021-09243-y. PMID: 34651287
Plummer-Vinson Syndrome.
Liu CC, Lin YS
Ear Nose Throat J 2019 Jun;98(5):259-260. doi: 10.1177/0145561319850412. PMID: 31208220
Orofacial manifestations of hematological disorders: anemia and hemostatic disorders.
Adeyemo TA, Adeyemo WL, Adediran A, Akinbami AJ, Akanmu AS
Indian J Dent Res 2011 May-Jun;22(3):454-61. doi: 10.4103/0970-9290.87070. PMID: 22048588
Plummer-Vinson syndrome.
Hefaiedh R, Boutreaa Y, Ouakaa-Kchaou A, Gargouri D, Elloumi H, Kochlef A, Romani M, Kilani A, Kharrat J, Ghorbel A
Tunis Med 2010 Oct;88(10):721-4. PMID: 20890819
Plummer-Vinson syndrome.
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article

Therapy

Paterson-Brown-Kelly syndrome.
Bakshi SS
Gastroenterol Hepatol 2018 Dec;41(10):650-651. Epub 2018 Jun 6 doi: 10.1016/j.gastrohep.2018.05.010. PMID: 29884482
Plummer-Vinson Syndrome.
Bakshi SS
Mayo Clin Proc 2016 Mar;91(3):404. doi: 10.1016/j.mayocp.2015.11.002. PMID: 26944249
Plummer-Vinson syndrome.
Phatak S, Redkar N, Patil MA, Kuwar A
BMJ Case Rep 2012 Jul 25;2012 doi: 10.1136/bcr-2012-006403. PMID: 22843759Free PMC Article
Plummer-Vinson syndrome.
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Plummer-Vinson syndrome.
Atmatzidis K, Papaziogas B, Pavlidis T, Mirelis Ch, Papaziogas T
Dis Esophagus 2003;16(2):154-7. doi: 10.1046/j.1442-2050.2003.00316.x. PMID: 12823219

Prognosis

Plummer-Vinson syndrome: A decade's experience of 132 cases from a single center.
Patil M, Malipatel R, Devarbhavi H
J Gastroenterol Hepatol 2021 Jan;36(1):181-185. Epub 2020 Jun 29 doi: 10.1111/jgh.15139. PMID: 32525241
Plummer-Vinson syndrome.
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Plummer-Vinson syndrome and dilation therapy: a report of two cases.
Demirci F, Savaş MC, Kepkep N, Okan V, Yilmaz M, Büyükberber M, Gülşen MT
Turk J Gastroenterol 2005 Dec;16(4):224-7. PMID: 16547853
Plummer-Vinson syndrome. A case report and literature review.
Hoffman RM, Jaffe PE
Arch Intern Med 1995 Oct 9;155(18):2008-11. doi: 10.1001/archinte.155.18.2008. PMID: 7575056
Rise and fall of the Plummer-Vinson syndrome.
Chen TS, Chen PS
J Gastroenterol Hepatol 1994 Nov-Dec;9(6):654-8. doi: 10.1111/j.1440-1746.1994.tb01581.x. PMID: 7865729

Clinical prediction guides

Plummer-Vinson Syndrome in Children.
Butori M, Mahmoudi S, Dugelay-Ecochard E, Belarbi N, Bellaïche M, Hugot JP, Viala J
J Pediatr Gastroenterol Nutr 2015 Nov;61(5):547-52. doi: 10.1097/MPG.0000000000000842. PMID: 26502163
Plummer-Vinson syndrome.
Hefaiedh R, Boutreaa Y, Ouakaa-Kchaou A, Gargouri D, Elloumi H, Kochlef A, Romani M, Kilani A, Kharrat J, Ghorbel A
Tunis Med 2010 Oct;88(10):721-4. PMID: 20890819
Plummer-Vinson syndrome.
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
The Brown Kelly-Paterson or Plummer-Vinson syndrome: an old score finally settled.
Slater SD
J R Coll Physicians Lond 1991 Jul;25(3):257-8. PMID: 1801780Free PMC Article
Nutrition and cancer.
Wynder EL
Fed Proc 1976 May 1;35(6):1309-15. PMID: 770204

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