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Plummer-Vinson syndrome

MedGen UID:
45967
Concept ID:
C0032249
Disease or Syndrome
Synonyms: Dysphagia sideropenica; Kelly's syndrome; Paterson's syndrome; Paterson-Brown-Kelly syndrome; Paterson-Kelly syndrome
SNOMED CT: Brown-Kelly-Paterson syndrome (80126007); Plummer-Vinson-Patterson-Kelly syndrome (80126007); Plummer-Vinson syndrome (80126007); Paterson-Kelly syndrome (80126007); Sideropenic dysphagia (80126007)
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
Concept ID:
CN307042
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
 
Monarch Initiative: MONDO:0018895
Orphanet: ORPHA54028

Definition

Plummer-Vinson or Paterson-Kelly syndrome presents as a classical triad of dysphagia, iron-deficiency anemia and esophageal webs. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPlummer-Vinson syndrome
Follow this link to review classifications for Plummer-Vinson syndrome in Orphanet.

Professional guidelines

PubMed

Walker J, Baran R, Vélez N, Jellinek N
J Eur Acad Dermatol Venereol 2016 Nov;30(11):1985-1991. Epub 2016 Aug 17 doi: 10.1111/jdv.13610. PMID: 27531645
Lightdale CJ, Winawer SJ
Semin Oncol 1984 Jun;11(2):101-12. PMID: 6729490

Recent clinical studies

Etiology

Harmouch F, Liaquat H, Chaput KJ, Geme B
Am J Case Rep 2021 Apr 24;22:e929899. doi: 10.12659/AJCR.929899. PMID: 33895769Free PMC Article
Patil M, Malipatel R, Devarbhavi H
J Gastroenterol Hepatol 2021 Jan;36(1):181-185. Epub 2020 Jun 29 doi: 10.1111/jgh.15139. PMID: 32525241
Shah KR, Boland CR, Patel M, Thrash B, Menter A
J Am Acad Dermatol 2013 Feb;68(2):189.e1-21; quiz 210. doi: 10.1016/j.jaad.2012.10.037. PMID: 23317980
Hefaiedh R, Boutreaa Y, Ouakaa-Kchaou A, Gargouri D, Elloumi H, Kochlef A, Romani M, Kilani A, Kharrat J, Ghorbel A
Tunis Med 2010 Oct;88(10):721-4. PMID: 20890819
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article

Diagnosis

Binet Q, Delorme A
N Engl J Med 2024 Feb 15;390(7):652. Epub 2024 Feb 10 doi: 10.1056/NEJMicm2309721. PMID: 38345572
de Carvalho JF, Lerner A
Immunol Res 2022 Feb;70(1):19-22. Epub 2021 Oct 14 doi: 10.1007/s12026-021-09243-y. PMID: 34651287
Liu CC, Lin YS
Ear Nose Throat J 2019 Jun;98(5):259-260. doi: 10.1177/0145561319850412. PMID: 31208220
Adeyemo TA, Adeyemo WL, Adediran A, Akinbami AJ, Akanmu AS
Indian J Dent Res 2011 May-Jun;22(3):454-61. doi: 10.4103/0970-9290.87070. PMID: 22048588
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article

Therapy

Bakshi SS
Gastroenterol Hepatol 2018 Dec;41(10):650-651. Epub 2018 Jun 6 doi: 10.1016/j.gastrohep.2018.05.010. PMID: 29884482
Bakshi SS
Mayo Clin Proc 2016 Mar;91(3):404. doi: 10.1016/j.mayocp.2015.11.002. PMID: 26944249
Phatak S, Redkar N, Patil MA, Kuwar A
BMJ Case Rep 2012 Jul 25;2012 doi: 10.1136/bcr-2012-006403. PMID: 22843759Free PMC Article
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Atmatzidis K, Papaziogas B, Pavlidis T, Mirelis Ch, Papaziogas T
Dis Esophagus 2003;16(2):154-7. doi: 10.1046/j.1442-2050.2003.00316.x. PMID: 12823219

Prognosis

Patil M, Malipatel R, Devarbhavi H
J Gastroenterol Hepatol 2021 Jan;36(1):181-185. Epub 2020 Jun 29 doi: 10.1111/jgh.15139. PMID: 32525241
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Demirci F, Savaş MC, Kepkep N, Okan V, Yilmaz M, Büyükberber M, Gülşen MT
Turk J Gastroenterol 2005 Dec;16(4):224-7. PMID: 16547853
Hoffman RM, Jaffe PE
Arch Intern Med 1995 Oct 9;155(18):2008-11. doi: 10.1001/archinte.155.18.2008. PMID: 7575056
Chen TS, Chen PS
J Gastroenterol Hepatol 1994 Nov-Dec;9(6):654-8. doi: 10.1111/j.1440-1746.1994.tb01581.x. PMID: 7865729

Clinical prediction guides

Butori M, Mahmoudi S, Dugelay-Ecochard E, Belarbi N, Bellaïche M, Hugot JP, Viala J
J Pediatr Gastroenterol Nutr 2015 Nov;61(5):547-52. doi: 10.1097/MPG.0000000000000842. PMID: 26502163
Hefaiedh R, Boutreaa Y, Ouakaa-Kchaou A, Gargouri D, Elloumi H, Kochlef A, Romani M, Kilani A, Kharrat J, Ghorbel A
Tunis Med 2010 Oct;88(10):721-4. PMID: 20890819
Novacek G
Orphanet J Rare Dis 2006 Sep 15;1:36. doi: 10.1186/1750-1172-1-36. PMID: 16978405Free PMC Article
Slater SD
J R Coll Physicians Lond 1991 Jul;25(3):257-8. PMID: 1801780Free PMC Article
Wynder EL
Fed Proc 1976 May 1;35(6):1309-15. PMID: 770204

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