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Pneumocephalus

MedGen UID:
45970
•Concept ID:
C0032268
•
Disease or Syndrome
Synonyms: Airocele, Cranial; Airoceles, Cranial; Cranial Airocele; Cranial Airoceles; Cranial Pneumocyst; Cranial Pneumocysts; Gas, Intracranial; Intracranial Gas; Pneumocyst, Cranial; Pneumocysts, Cranial
SNOMED CT: Pneumocephalus (14415006); Airocele (14415006)

Definition

The presence of air or gas within the cranial cavity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPneumocephalus

Professional guidelines

PubMed

Postoperative Obstructive Sleep Apnea Management Following Endoscopic Pituitary Surgery: A Systematic Review.
Risbud A, Kuan EC, Wu AW, Mamelak AN, Tang DM
World Neurosurg 2023 Aug;176:143-148. Epub 2023 May 4 doi: 10.1016/j.wneu.2023.04.116. PMID: 37149088
Assessment of safety and effectiveness of non-neurosurgical management for minimal traumatic brain injury (TBI).
Chen JW, Yengo-Kahn A, Chotai S, Bhamidipati A, Smith C, Davis P, Reynolds RA, Boyd MP, Barrett TW, Compton ES, Dennis BM, Norris MS, Patel MB, Schwarz JP, Thomason NR, Thompson RC, Guillamondegui OD
Injury 2023 Jan;54(1):82-86. Epub 2022 Aug 6 doi: 10.1016/j.injury.2022.08.009. PMID: 36028374
Occurrence and management of postoperative pneumocephalus using the semi-sitting position in vestibular schwannoma surgery.
Machetanz K, Leuze F, Mounts K, Trakolis L, Gugel I, Grimm F, Tatagiba M, Naros G
Acta Neurochir (Wien) 2020 Nov;162(11):2629-2636. Epub 2020 Jul 25 doi: 10.1007/s00701-020-04504-5. PMID: 32712719Free PMC Article

Recent clinical studies

Etiology

MER and increased operative time are not risk factors for the formation of pneumocephalus during DBS.
Iess G, Bonomo G, Levi V, Aquino D, Zekaj E, Mezza F, Servello D
Sci Rep 2023 Jun 8;13(1):9324. doi: 10.1038/s41598-023-30289-5. PMID: 37291256Free PMC Article
Postoperative pneumocephalus and recurrence and outcome of chronic subdural hematoma: a systematic review and meta-analysis.
Guo X, Wu L, Ou Y, Yu X, Zhu B, Yang C, Liu W
Neurosurg Rev 2022 Dec 9;46(1):13. doi: 10.1007/s10143-022-01925-x. PMID: 36481957
Lumbar drains: Practical understanding and application for the otolaryngologist.
Livingston AJ, Laing B, Zwagerman NT, Harris MS
Am J Otolaryngol 2020 Nov-Dec;41(6):102740. Epub 2020 Sep 19 doi: 10.1016/j.amjoto.2020.102740. PMID: 32979671
Take it seriously or not: postoperative pneumocephalus in CSDH patients?
Huang GH, Li XC, Ren L, Dai RX, Sun ZL, Jiang XF, Feng DF
Br J Neurosurg 2020 Jun;34(3):284-289. Epub 2020 Feb 23 doi: 10.1080/02688697.2020.1729343. PMID: 32090624
Neurologic Complications and Treatment.
Welch KC
Otolaryngol Clin North Am 2015 Oct;48(5):769-82. Epub 2015 Jul 2 doi: 10.1016/j.otc.2015.05.005. PMID: 26143103

Diagnosis

Pituitary Adenoma "Pneumo-Apoplexy".
Almeida AI, Sousa JM, Sampaio L
World Neurosurg 2023 Apr;172:10-11. Epub 2023 Jan 20 doi: 10.1016/j.wneu.2023.01.052. PMID: 36682526
Air travel with pneumocephalus: a systematic review.
Bichsel O, Hauck A, Oertel M
Acta Neurochir (Wien) 2022 Sep;164(9):2395-2400. Epub 2022 Jul 6 doi: 10.1007/s00701-022-05297-5. PMID: 35794427Free PMC Article
Tension Pneumocephalus.
Prichard RG
R I Med J (2013) 2021 Jun 1;104(5):47-48. PMID: 34044439
Causes of pneumocephalus and when to be concerned about it.
Cunqueiro A, Scheinfeld MH
Emerg Radiol 2018 Aug;25(4):331-340. Epub 2018 Mar 15 doi: 10.1007/s10140-018-1595-x. PMID: 29546674
Spontaneous otogenic pneumocephalus.
Mohammed el R, Profant M
Acta Otolaryngol 2011 Jun;131(6):670-4. Epub 2011 Jan 24 doi: 10.3109/00016489.2010.541941. PMID: 21254960

Therapy

MER and increased operative time are not risk factors for the formation of pneumocephalus during DBS.
Iess G, Bonomo G, Levi V, Aquino D, Zekaj E, Mezza F, Servello D
Sci Rep 2023 Jun 8;13(1):9324. doi: 10.1038/s41598-023-30289-5. PMID: 37291256Free PMC Article
Techniques for pneumocephalus and brain shift reduction in DBS surgery: a review of the literature.
Beggio G, Raneri F, Rustemi O, Scerrati A, Zambon G, Piacentino M
Neurosurg Rev 2020 Feb;43(1):95-99. Epub 2020 Jan 2 doi: 10.1007/s10143-019-01220-2. PMID: 31897886
Image: Extensive Pneumocephalus.
Liu H, Wang W
World Neurosurg 2018 Jan;109:127-128. Epub 2017 Sep 30 doi: 10.1016/j.wneu.2017.09.151. PMID: 28974412
Tension pneumocephalus.
Pulickal GG, Sitoh YY, Ng WH
Singapore Med J 2014 Mar;55(3):e46-8. doi: 10.11622/smedj.2014041. PMID: 24664394Free PMC Article
Imaging of the post-operative cranium.
Sinclair AG, Scoffings DJ
Radiographics 2010 Mar;30(2):461-82. doi: 10.1148/rg.302095115. PMID: 20228329

Prognosis

Clinical Significance of Pneumocephalus in Pediatric Mild Traumatic Brain Injury.
Hanalioglu D, Elbir C, Sahin OS, Ercandirli AK, Sahin B, Turkoglu ME, Kertmen HH, Hanalioglu S
Pediatr Emerg Care 2023 Nov 1;39(11):836-840. Epub 2023 Oct 8 doi: 10.1097/PEC.0000000000003060. PMID: 37815282
MER and increased operative time are not risk factors for the formation of pneumocephalus during DBS.
Iess G, Bonomo G, Levi V, Aquino D, Zekaj E, Mezza F, Servello D
Sci Rep 2023 Jun 8;13(1):9324. doi: 10.1038/s41598-023-30289-5. PMID: 37291256Free PMC Article
Air travel with pneumocephalus: a systematic review.
Bichsel O, Hauck A, Oertel M
Acta Neurochir (Wien) 2022 Sep;164(9):2395-2400. Epub 2022 Jul 6 doi: 10.1007/s00701-022-05297-5. PMID: 35794427Free PMC Article
Take it seriously or not: postoperative pneumocephalus in CSDH patients?
Huang GH, Li XC, Ren L, Dai RX, Sun ZL, Jiang XF, Feng DF
Br J Neurosurg 2020 Jun;34(3):284-289. Epub 2020 Feb 23 doi: 10.1080/02688697.2020.1729343. PMID: 32090624
Mount Fuji Sign.
Bhoil R, Kumar R, Chopra R, Bhoil S
Intern Emerg Med 2020 Jun;15(4):715-716. Epub 2020 Jan 1 doi: 10.1007/s11739-019-02262-6. PMID: 31893347

Clinical prediction guides

Clinical Significance of Pneumocephalus in Pediatric Mild Traumatic Brain Injury.
Hanalioglu D, Elbir C, Sahin OS, Ercandirli AK, Sahin B, Turkoglu ME, Kertmen HH, Hanalioglu S
Pediatr Emerg Care 2023 Nov 1;39(11):836-840. Epub 2023 Oct 8 doi: 10.1097/PEC.0000000000003060. PMID: 37815282
MER and increased operative time are not risk factors for the formation of pneumocephalus during DBS.
Iess G, Bonomo G, Levi V, Aquino D, Zekaj E, Mezza F, Servello D
Sci Rep 2023 Jun 8;13(1):9324. doi: 10.1038/s41598-023-30289-5. PMID: 37291256Free PMC Article
Non-acute subdural hematoma: estimation of recurrence using CT-volumetric measurements.
Opsenak R, Hanko M, Benco M, Snopko P, Richterova R, Kolarovszki B
Bratisl Lek Listy 2023;124(1):3-11. doi: 10.4149/BLL_2023_001. PMID: 36519601
Take it seriously or not: postoperative pneumocephalus in CSDH patients?
Huang GH, Li XC, Ren L, Dai RX, Sun ZL, Jiang XF, Feng DF
Br J Neurosurg 2020 Jun;34(3):284-289. Epub 2020 Feb 23 doi: 10.1080/02688697.2020.1729343. PMID: 32090624
Image: Extensive Pneumocephalus.
Liu H, Wang W
World Neurosurg 2018 Jan;109:127-128. Epub 2017 Sep 30 doi: 10.1016/j.wneu.2017.09.151. PMID: 28974412

Recent systematic reviews

Use of oxygen therapy for pneumocephalus: a systematic review.
Kim BJH, Ji MY, Chen JCC, Correia JA, Law AJJ, Kow CY
Neurosurg Rev 2024 Jan 4;47(1):30. doi: 10.1007/s10143-023-02261-4. PMID: 38172487
Postoperative pneumocephalus and recurrence and outcome of chronic subdural hematoma: a systematic review and meta-analysis.
Guo X, Wu L, Ou Y, Yu X, Zhu B, Yang C, Liu W
Neurosurg Rev 2022 Dec 9;46(1):13. doi: 10.1007/s10143-022-01925-x. PMID: 36481957
Air travel with pneumocephalus: a systematic review.
Bichsel O, Hauck A, Oertel M
Acta Neurochir (Wien) 2022 Sep;164(9):2395-2400. Epub 2022 Jul 6 doi: 10.1007/s00701-022-05297-5. PMID: 35794427Free PMC Article
Burr hole drainage and burr hole drainage with irrigation to treat chronic subdural hematoma: A systematic review and meta-analysis.
Yuan Y, Wang QP, Cao YL, Zhang H, Burkutally MSN, Budryte K, Xiong N
Medicine (Baltimore) 2018 Aug;97(33):e11827. doi: 10.1097/MD.0000000000011827. PMID: 30113471Free PMC Article
A systematic review of causes of sudden and severe headache (Thunderclap Headache): should lists be evidence based?
Devenney E, Neale H, Forbes RB
J Headache Pain 2014 Aug 14;15(1):49. doi: 10.1186/1129-2377-15-49. PMID: 25123846Free PMC Article

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