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Adrenal hemorrhage

MedGen UID:
472896
•Concept ID:
C0151693
•
Pathologic Function
Synonym: Adrenal Hemorrhage
SNOMED CT: Adrenal hemorrhage (49111001)

Definition

Hemorrhage and necrosis of the adrenal gland tissue. Bilateral and extensive hemorrhage may lead to acute adrenal insufficiency, shock, and death. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdrenal hemorrhage

Professional guidelines

PubMed

Imaging modalities and management of prenatally diagnosed suprarenal masses: an updated literature review and the experience at a high volume Fetal Treatment Center.
Schwab ME, Braun HJ, Padilla BE
J Matern Fetal Neonatal Med 2022 Jan;35(2):308-315. Epub 2020 Jan 26 doi: 10.1080/14767058.2020.1716719. PMID: 31984817Free PMC Article
Clinical update on the management of adrenal hemorrhage.
Simon DR, Palese MA
Curr Urol Rep 2009 Jan;10(1):78-83. doi: 10.1007/s11934-009-0014-y. PMID: 19116100
Bilateral massive adrenal hemorrhage: early recognition and treatment.
Rao RH, Vagnucci AH, Amico JA
Ann Intern Med 1989 Feb 1;110(3):227-35. doi: 10.7326/0003-4819-110-3-227. PMID: 2643380

Recent clinical studies

Etiology

Adrenal Hemorrhage: A Review.
Doiron T, Odom LA, Magann EF
Obstet Gynecol Surv 2023 Jan;78(1):69-74. doi: 10.1097/OGX.0000000000001080. PMID: 36607202
Approach to the Patient With Adrenal Hemorrhage.
Elhassan YS, Ronchi CL, Wijewickrama P, Baldeweg SE
J Clin Endocrinol Metab 2023 Mar 10;108(4):995-1006. doi: 10.1210/clinem/dgac672. PMID: 36404284Free PMC Article
Adrenal hemorrhage: A single center experience and literature review.
Karwacka IM, Obołończyk Ł, Sworczak K
Adv Clin Exp Med 2018 May;27(5):681-687. doi: 10.17219/acem/68897. PMID: 29616752
Fondaparinux-associated heparin-induced thrombocytopenia.
Bhatt VR, Aryal MR, Shrestha R, Armitage JO
Eur J Haematol 2013 Nov;91(5):437-41. Epub 2013 Aug 20 doi: 10.1111/ejh.12179. PMID: 23905719
Adrenal crisis.
Chin R
Crit Care Clin 1991 Jan;7(1):23-42. PMID: 2007218

Diagnosis

Adrenal Hemorrhage: A Review.
Doiron T, Odom LA, Magann EF
Obstet Gynecol Surv 2023 Jan;78(1):69-74. doi: 10.1097/OGX.0000000000001080. PMID: 36607202
Adrenal hemorrhage and hemorrhagic masses; diagnostic workup and imaging findings.
Badawy M, Gaballah AH, Ganeshan D, Abdelalziz A, Remer EM, Alsabbagh M, Westphalen A, Siddiqui MA, Taffel MT, Itani M, Shaaban AM, Elsayes KM
Br J Radiol 2021 Nov 1;94(1127):20210753. Epub 2021 Aug 31 doi: 10.1259/bjr.20210753. PMID: 34464549Free PMC Article
Adrenal hemorrhage: A single center experience and literature review.
Karwacka IM, Obołończyk Ł, Sworczak K
Adv Clin Exp Med 2018 May;27(5):681-687. doi: 10.17219/acem/68897. PMID: 29616752
Adrenal imaging.
Korobkin M, Francis IR
Semin Ultrasound CT MR 1995 Aug;16(4):317-30. doi: 10.1016/0887-2171(95)90036-5. PMID: 7576778
Adrenal crisis.
Chin R
Crit Care Clin 1991 Jan;7(1):23-42. PMID: 2007218

Therapy

Adrenal Hemorrhage: A Review.
Doiron T, Odom LA, Magann EF
Obstet Gynecol Surv 2023 Jan;78(1):69-74. doi: 10.1097/OGX.0000000000001080. PMID: 36607202
Adrenal hemorrhage: A single center experience and literature review.
Karwacka IM, Obołończyk Ł, Sworczak K
Adv Clin Exp Med 2018 May;27(5):681-687. doi: 10.17219/acem/68897. PMID: 29616752
Bilateral adrenal hemorrhage.
Fakih H, Beel BC, Shychuk A, Ataya A
Intensive Care Med 2017 Mar;43(3):447-448. Epub 2016 Oct 13 doi: 10.1007/s00134-016-4587-x. PMID: 27738706
Fondaparinux-associated heparin-induced thrombocytopenia.
Bhatt VR, Aryal MR, Shrestha R, Armitage JO
Eur J Haematol 2013 Nov;91(5):437-41. Epub 2013 Aug 20 doi: 10.1111/ejh.12179. PMID: 23905719
Bilateral massive adrenal hemorrhage: early recognition and treatment.
Rao RH, Vagnucci AH, Amico JA
Ann Intern Med 1989 Feb 1;110(3):227-35. doi: 10.7326/0003-4819-110-3-227. PMID: 2643380

Prognosis

Adrenal hemorrhage: A single center experience and literature review.
Karwacka IM, Obołończyk Ł, Sworczak K
Adv Clin Exp Med 2018 May;27(5):681-687. doi: 10.17219/acem/68897. PMID: 29616752
Bilateral adrenal hemorrhage.
Fakih H, Beel BC, Shychuk A, Ataya A
Intensive Care Med 2017 Mar;43(3):447-448. Epub 2016 Oct 13 doi: 10.1007/s00134-016-4587-x. PMID: 27738706
Fondaparinux-associated heparin-induced thrombocytopenia.
Bhatt VR, Aryal MR, Shrestha R, Armitage JO
Eur J Haematol 2013 Nov;91(5):437-41. Epub 2013 Aug 20 doi: 10.1111/ejh.12179. PMID: 23905719
Traumatic adrenal injuries.
Gabal-Shehab L, Alagiri M
J Urol 2005 Apr;173(4):1330-1. doi: 10.1097/01.ju.0000155459.11926.61. PMID: 15758794
Bilateral massive adrenal hemorrhage: early recognition and treatment.
Rao RH, Vagnucci AH, Amico JA
Ann Intern Med 1989 Feb 1;110(3):227-35. doi: 10.7326/0003-4819-110-3-227. PMID: 2643380

Clinical prediction guides

Severity of traumatic adrenal injury does not meaningfully affect clinical outcomes.
Nguyen J, Ude N, Holloway N, Tootla Y, Archer-Arroyo K, Novack J, Tran J, Isaacson A, Drake M, Smith RN, Sciarretta J, Udobi K, Sola R Jr, Williams K, Butler C, Grant AA, Morse BC, Herr KD
Emerg Radiol 2022 Oct;29(5):895-901. Epub 2022 Jul 13 doi: 10.1007/s10140-022-02069-7. PMID: 35829928
Imaging modalities and management of prenatally diagnosed suprarenal masses: an updated literature review and the experience at a high volume Fetal Treatment Center.
Schwab ME, Braun HJ, Padilla BE
J Matern Fetal Neonatal Med 2022 Jan;35(2):308-315. Epub 2020 Jan 26 doi: 10.1080/14767058.2020.1716719. PMID: 31984817Free PMC Article
Adrenal hemorrhage: A single center experience and literature review.
Karwacka IM, Obołończyk Ł, Sworczak K
Adv Clin Exp Med 2018 May;27(5):681-687. doi: 10.17219/acem/68897. PMID: 29616752
From the radiologic pathology archives: Adrenal tumors and tumor-like conditions in the adult: radiologic-pathologic correlation.
Lattin GE Jr, Sturgill ED, Tujo CA, Marko J, Sanchez-Maldonado KW, Craig WD, Lack EE
Radiographics 2014 May-Jun;34(3):805-29. doi: 10.1148/rg.343130127. PMID: 24819798
Fondaparinux-associated heparin-induced thrombocytopenia.
Bhatt VR, Aryal MR, Shrestha R, Armitage JO
Eur J Haematol 2013 Nov;91(5):437-41. Epub 2013 Aug 20 doi: 10.1111/ejh.12179. PMID: 23905719

Recent systematic reviews

Bilateral massive adrenal hemorrhage.
Rao RH
Med Clin North Am 1995 Jan;79(1):107-29. doi: 10.1016/s0025-7125(16)30087-6. PMID: 7808087

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