U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hyaline degeneration

MedGen UID:
473044
•Concept ID:
C0333438
•
Pathologic Function
Synonyms: Hyaline thickening; Hyalinization; Hyalinosis
SNOMED CT: Hyaline degeneration (19010006); Hyaline thickening (19010006); Hyalinization (19010006); Hyalinosis (19010006)

Definition

A process of tissue replacement where the tissue is being replaced by hyaline or the tissue has degenerated to hyaline. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyaline degeneration

Professional guidelines

PubMed

Clinical value of contrast-enhanced ultrasound for the differential diagnosis of specific subtypes of uterine leiomyomas.
Li Z, Zhang P, Shen H, Ding B, Wang H, Li J, Shen Y
J Obstet Gynaecol Res 2021 Jan;47(1):311-319. Epub 2020 Oct 18 doi: 10.1111/jog.14527. PMID: 33073436
Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis, and treatment.
Murase E, Siegelman ES, Outwater EK, Perez-Jaffe LA, Tureck RW
Radiographics 1999 Sep-Oct;19(5):1179-97. doi: 10.1148/radiographics.19.5.g99se131179. PMID: 10489175
Diffuse, perinodular, and other patterns of hydropic degeneration within and adjacent to uterine leiomyomas. Problems in differential diagnosis.
Clement PB, Young RH, Scully RE
Am J Surg Pathol 1992 Jan;16(1):26-32. doi: 10.1097/00000478-199201000-00004. PMID: 1309411

Recent clinical studies

Etiology

Pathological features of Brucella spondylitis: A single-center study.
Ma H, Zhang N, Liu J, Wang X, Yang Z, Lou C, Ji J, Zhai X, Niu N
Ann Diagn Pathol 2022 Jun;58:151910. Epub 2022 Feb 2 doi: 10.1016/j.anndiagpath.2022.151910. PMID: 35134730
The radiologic (CT/MRI)-pathological correlations of the salivary duct carcinoma (SDC) with hyaline degeneration and peripheral nerve invasion.
Kazawa N, Shibamoto Y, Hirose Y, Yamashita Y
Dentomaxillofac Radiol 2021 Oct 1;50(7):20200603. Epub 2021 Apr 20 doi: 10.1259/dmfr.20200603. PMID: 33877880Free PMC Article
Leksell Stereotactic Radiosurgery for Cavernous Malformations.
Lunsford LD, Niranjan A, Kano H, Monaco Iii EA, Flickinger JC
Prog Neurol Surg 2019;34:260-266. Epub 2019 May 16 doi: 10.1159/000493072. PMID: 31096254
Leiomyoma: Its Variants And Secondary Changes A Five-Year Study.
Naz S, Rehman A, Riyaz A, Jehangir F, Naeem S, Iqbal T
J Ayub Med Coll Abbottabad 2019 Apr-Jun;31(2):192-195. PMID: 31094115
IV. Uterine fibroid embolization: follow-up.
Lipman JC, Smith SJ, Spies JB, Siskin GP, Machan LS, Bonn J, Worthington-Kirsch RL, Goodwin SC, Hovsepian DM
Tech Vasc Interv Radiol 2002 Mar;5(1):44-55. doi: 10.1053/tvir.2002.124102. PMID: 12098107

Diagnosis

Pathological features of Brucella spondylitis: A single-center study.
Ma H, Zhang N, Liu J, Wang X, Yang Z, Lou C, Ji J, Zhai X, Niu N
Ann Diagn Pathol 2022 Jun;58:151910. Epub 2022 Feb 2 doi: 10.1016/j.anndiagpath.2022.151910. PMID: 35134730
Glomus tumor of the crissum: A case report and review of literature.
Zheng Y, Liu X, Mao Y, Lin M
Indian J Pathol Microbiol 2022 Jan-Mar;65(1):164-166. doi: 10.4103/IJPM.IJPM_1237_20. PMID: 35074986
Clinicopathological features of phlebosclerotic colitis.
Xu J, Jin M, Jiang Z, Ke Q, Li A, Zhu T, Lai M
Pathol Res Pract 2020 Nov;216(11):153193. Epub 2020 Aug 28 doi: 10.1016/j.prp.2020.153193. PMID: 32927306
Morphology and Evaluation of Renal Fibrosis.
Chen PS, Li YP, Ni HF
Adv Exp Med Biol 2019;1165:17-36. doi: 10.1007/978-981-13-8871-2_2. PMID: 31399959
Hormonal pathology of the endometrium.
Deligdisch L
Mod Pathol 2000 Mar;13(3):285-94. doi: 10.1038/modpathol.3880050. PMID: 10757339

Therapy

A comparative histopathological study of vocal fold polyps in smokers versus non-smokers.
Effat KG, Milad M
J Laryngol Otol 2015 May;129(5):484-8. Epub 2015 Mar 19 doi: 10.1017/S002221511500064X. PMID: 25788125
Verrucous form of chilblain lupus erythematosus.
Pock L, Petrovská P, Becvár R, Mandys V, Hercogová J
J Eur Acad Dermatol Venereol 2001 Sep;15(5):448-51. doi: 10.1046/j.1468-3083.2001.00346.x. PMID: 11763388
Hormonal pathology of the endometrium.
Deligdisch L
Mod Pathol 2000 Mar;13(3):285-94. doi: 10.1038/modpathol.3880050. PMID: 10757339
Pathologic changes in gonadotropin releasing hormone agonist analogue treated uterine leiomyomata.
Deligdisch L, Hirschmann S, Altchek A
Fertil Steril 1997 May;67(5):837-41. doi: 10.1016/s0015-0282(97)81394-5. PMID: 9130887
Comparison of skin and muscle biopsies before and after pentoxifylline treatment in patients with leg ulcers due to deep venous incompetence.
Angelides NS, von der Ahe CW, Themistocleus P
Int Angiol 1991 Apr-Jun;10(2):72-6. PMID: 1861090

Prognosis

Clinicopathological features of low-grade malignant endolymphatic sac tumors.
Wang HQ, Jie L, Shi HY
Pathol Res Pract 2018 Mar;214(3):431-435. Epub 2017 Dec 14 doi: 10.1016/j.prp.2017.12.007. PMID: 29482989
Retroperitoneal ancient schwannoma - case presentation.
Meşină C, Mogoantă SŞ, Cristian DA, Dumitrescu TV, Drăgoescu PO, Meşină-Botoran MI, Ciurea ME, Ghiluşi MC, Ciobanu D
Rom J Morphol Embryol 2015;56(4):1517-22. PMID: 26743303
Lipofibroadenoma of the thymus: a case report.
Qu G, Yu G, Zhang Q, Ma J, Wang X
Diagn Pathol 2013 Jul 15;8:117. doi: 10.1186/1746-1596-8-117. PMID: 23856156Free PMC Article
IV. Uterine fibroid embolization: follow-up.
Lipman JC, Smith SJ, Spies JB, Siskin GP, Machan LS, Bonn J, Worthington-Kirsch RL, Goodwin SC, Hovsepian DM
Tech Vasc Interv Radiol 2002 Mar;5(1):44-55. doi: 10.1053/tvir.2002.124102. PMID: 12098107
MR detection of degenerating uterine leiomyomas.
Okizuka H, Sugimura K, Takemori M, Obayashi C, Kitao M, Ishida T
J Comput Assist Tomogr 1993 Sep-Oct;17(5):760-6. doi: 10.1097/00004728-199309000-00018. PMID: 8370831

Clinical prediction guides

Mixed epithelial and stromal tumor of the kidney: A retrospective clinicopathological evaluation.
Feng R, Zhang T, Ke C, Tao Y, Wang Y
Ann Diagn Pathol 2023 Apr;63:152088. Epub 2022 Dec 23 doi: 10.1016/j.anndiagpath.2022.152088. PMID: 36577187
Pathological features of Brucella spondylitis: A single-center study.
Ma H, Zhang N, Liu J, Wang X, Yang Z, Lou C, Ji J, Zhai X, Niu N
Ann Diagn Pathol 2022 Jun;58:151910. Epub 2022 Feb 2 doi: 10.1016/j.anndiagpath.2022.151910. PMID: 35134730
The radiologic (CT/MRI)-pathological correlations of the salivary duct carcinoma (SDC) with hyaline degeneration and peripheral nerve invasion.
Kazawa N, Shibamoto Y, Hirose Y, Yamashita Y
Dentomaxillofac Radiol 2021 Oct 1;50(7):20200603. Epub 2021 Apr 20 doi: 10.1259/dmfr.20200603. PMID: 33877880Free PMC Article
Analysis of 4 imaging features in patients with COVID-19.
Jin J, Gao DH, Mo X, Tan SP, Kou ZX, Chen YB, Cao JB, Chen WJ, Zhang YM, Li BQ, Huang KL, Xu BR, Tang XL, Wang YL
BMC Med Imaging 2020 Jul 23;20(1):84. doi: 10.1186/s12880-020-00484-1. PMID: 32703209Free PMC Article
Histological and biochemical evidence related to the collagen quality in torn rotator cuff tendons.
Varitimidis SE, Dailiana ZH, Christou D, Grafanaki K, Ioannou MG, Stathopoulos C, Malizos KN
Acta Orthop Belg 2016 Aug;82(2):179-188. PMID: 27682278

Recent systematic reviews

Primary pulmonary hyalinizing clear cell carcinoma with vocal-cord squamous cell carcinoma: a case report with systematic review.
Li Z, Li W, Xue L
Diagn Pathol 2023 Aug 8;18(1):90. doi: 10.1186/s13000-023-01376-y. PMID: 37553667Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...